Pathology of Symptomatic Tremors
Identifieur interne : 001471 ( Istex/Checkpoint ); précédent : 001470; suivant : 001472Pathology of Symptomatic Tremors
Auteurs : Marie Vidailhet [France] ; Charles-Pierre Jedynak [France] ; Pierre Pollak [France] ; Yves Agid [France]Source :
- Movement Disorders [ 0885-3185 ] ; 1998.
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- KwdEn :
Abstract
Symptomatic tremors are labeled in the literature under different names including rubral tremor, midbrain tremor, thalamic tremor, myorhythmia, Holmes' tremor, cerebellar tremor, and goal‐directed tremor. The most common tremor is a delayed‐onset postural and action tremor with a low frequency of 3 Hz and a proximal distribution. Resting irregular tremor is sometimes present. Mild cerebellar dysmetria is often detected. The lesions are mainly located in the thalamus, the brain stem, and the cerebellum, with secondary interruption and degeneration of various pathways and olivary hypertrophy. The more consistent lesions are found in the cerebello‐thalamocortical and dentato‐rubro‐olivary pathways. The role of superimposed dysfunction of the nigrostriatal system may account for the rest component. The role of the basal ganglia in the emergence and control of tremor is poorly understood.
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DOI: 10.1002/mds.870131309
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<front><div type="abstract" xml:lang="en">Symptomatic tremors are labeled in the literature under different names including rubral tremor, midbrain tremor, thalamic tremor, myorhythmia, Holmes' tremor, cerebellar tremor, and goal‐directed tremor. The most common tremor is a delayed‐onset postural and action tremor with a low frequency of 3 Hz and a proximal distribution. Resting irregular tremor is sometimes present. Mild cerebellar dysmetria is often detected. The lesions are mainly located in the thalamus, the brain stem, and the cerebellum, with secondary interruption and degeneration of various pathways and olivary hypertrophy. The more consistent lesions are found in the cerebello‐thalamocortical and dentato‐rubro‐olivary pathways. The role of superimposed dysfunction of the nigrostriatal system may account for the rest component. The role of the basal ganglia in the emergence and control of tremor is poorly understood.</div>
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