ParkinsonFranceV1, Hal, Corpus, bibRecord, 000854

Paradoxical increase of tyroxine hydroxylase-immunoreactive retinopetal fibers in the weaver mouse.

Identifieur interne : 000854 ( Hal/Corpus ); précédent : 000853; suivant : 000855

Paradoxical increase of tyroxine hydroxylase-immunoreactive retinopetal fibers in the weaver mouse.

Auteurs : A. Simon ; C. Savy ; E. Martin-Martinelli ; A. Douhou ; F. Frederic ; C. Verney ; J. Nguyen-Legros ; R. Raisman-Vozari

Source :

Brain Research [ 0006-8993 ] ; 2000.

RBID : Hal:hal-00080506

English descriptors

mix :
- Development, Parkinson's disease, Retinopetal fibres, Tyrosine hydroxylase, Weaver mouse, Whole-mounted retina, neuronal death.

Abstract

Weaver mice undergo apoptosis of the granule cell precursors of the cerebellum and nonapoptotic death of mesencephalic dopaminergic cells during post-natal development. In contrast, the number of retinal dopaminergic cells was transiently increased in weaver compared to control mice [C. Savy, E. Martin-Martinelli, A. Simon, C. Duyckaerts, C. Verney, C. Adelbrecht, R. Raisman-Vozari, J. Nguyen-Legros, Altered development of dopaminergic cells in the retina of weaver mice, J. Comp. Neurol. 1999;412:656-668]. While re-examining the retinas, we observed, in the nerve fiber layer, retinopetal tyrosine hydroxylase-immunoreactive fibers, which were dramatically increased in number throughout development and adulthood in the weaver compared to control mice.

Url:

https://hal.archives-ouvertes.fr/hal-00080506

DOI: 10.1016/S0165-3806(00)00030-4

Links to Exploration step

Hal:hal-00080506

Le document en format XML

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<imprint><date type="datePub">2000</date>
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<profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>Development</term>
<term>Parkinson's disease</term>
<term>Retinopetal fibres</term>
<term>Tyrosine hydroxylase</term>
<term>Weaver mouse</term>
<term>Whole-mounted retina</term>
<term>neuronal death</term>
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<front><div type="abstract" xml:lang="en">Weaver mice undergo apoptosis of the granule cell precursors of the cerebellum and nonapoptotic death of mesencephalic dopaminergic cells during post-natal development. In contrast, the number of retinal dopaminergic cells was transiently increased in weaver compared to control mice [C. Savy, E. Martin-Martinelli, A. Simon, C. Duyckaerts, C. Verney, C. Adelbrecht, R. Raisman-Vozari, J. Nguyen-Legros, Altered development of dopaminergic cells in the retina of weaver mice, J. Comp. Neurol. 1999;412:656-668]. While re-examining the retinas, we observed, in the nerve fiber layer, retinopetal tyrosine hydroxylase-immunoreactive fibers, which were dramatically increased in number throughout development and adulthood in the weaver compared to control mice.</div>
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            <author role="aut">              <persName>                <forename type="first">A.</forename>
                <surname>Simon</surname>
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            <author role="aut">              <persName>                <forename type="first">C.</forename>
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            <author role="aut">              <persName>                <forename type="first">A.</forename>
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            <author role="aut">              <persName>                <forename type="first">F.</forename>
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              <email type="domain">snv.jussieu.fr</email>
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            <author role="aut">              <persName>                <forename type="first">C.</forename>
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            <author role="aut">              <persName>                <forename type="first">J.</forename>
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            <author role="aut">              <persName>                <forename type="first">R.</forename>
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              <email type="domain">cfx.ap-hop-paris.fr</email>
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            <funder>This work was supported by INSERM</funder>
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                <author role="aut">                  <persName>                    <forename type="first">C.</forename>
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                  <email type="domain">snv.jussieu.fr</email>
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                <author role="aut">                  <persName>                    <forename type="first">C.</forename>
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                </author>
                <author role="aut">                  <persName>                    <forename type="first">J.</forename>
                    <surname>Nguyen-Legros</surname>
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                  <idno type="halauthorid">107581</idno>
                  <affiliation ref="#struct-15416"></affiliation>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">R.</forename>
                    <surname>Raisman-Vozari</surname>
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                <term xml:lang="en">Tyrosine hydroxylase</term>
                <term xml:lang="en">Weaver mouse</term>
                <term xml:lang="en">Retinopetal fibres</term>
                <term xml:lang="en">Development</term>
                <term xml:lang="en">neuronal death</term>
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            <abstract xml:lang="en">Weaver mice undergo apoptosis of the granule cell precursors of the cerebellum and nonapoptotic death of mesencephalic dopaminergic cells during post-natal development. In contrast, the number of retinal dopaminergic cells was transiently increased in weaver compared to control mice [C. Savy, E. Martin-Martinelli, A. Simon, C. Duyckaerts, C. Verney, C. Adelbrecht, R. Raisman-Vozari, J. Nguyen-Legros, Altered development of dopaminergic cells in the retina of weaver mice, J. Comp. Neurol. 1999;412:656-668]. While re-examining the retinas, we observed, in the nerve fiber layer, retinopetal tyrosine hydroxylase-immunoreactive fibers, which were dramatically increased in number throughout development and adulthood in the weaver compared to control mice.</abstract>
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	La maladie de Parkinson en France (serveur d'exploration)
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La maladie de Parkinson en France (serveur d'exploration)

Paradoxical increase of tyroxine hydroxylase-immunoreactive retinopetal fibers in the weaver mouse.

Paradoxical increase of tyroxine hydroxylase-immunoreactive retinopetal fibers in the weaver mouse.

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