ParkinsonFranceV1, Hal, Corpus, bibRecord, 000632

Lifetime of Itrel II pulse generators for subthalamic nucleus stimulation in Parkinson's disease.

Identifieur interne : 000632 ( Hal/Corpus ); précédent : 000631; suivant : 000633

Lifetime of Itrel II pulse generators for subthalamic nucleus stimulation in Parkinson's disease.

Auteurs : Mathieu Anheim ; Valérie Fraix ; Stéphan Chabardès ; Paul Krack ; Alim-Louis Benabid ; Pierre Pollak

Source :

Movement Disorders [ 0885-3185 ] ; 2007-12.

RBID : Hal:inserm-00382268

Abstract

The efficacy of bilateral subthalamic nucleus (STN) stimulation in Parkinson's disease (PD) is well-established but little is known about the lifetime of implanted pulse generators (IPG). To investigate the lifetime of the bilaterally implanted Itrel II(R) (Medtronic, Minneapolis) pulse generator, the first 49 consecutive patients with PD having been operated on at our center for bilateral STN chronic stimulation were reviewed with noting of the stimulation parameters in use prior to IPG replacement. The mean electrical voltage was 3.2 +/- 0.3 V, mean pulse width was 65 +/- 10 mus, and mean frequency was 145 +/- 16 Hz. Replacement of an IPG was anticipated in 25% due to unilateral low-battery signaling, or end of life. In either case, replacement of the contralateral IPG was undertaken simultaneously. The mean IPG lifetime was 83 +/- 14 [40-113] months. The IPG lifetime correlated with the total electrical energy delivered (P = 0.002, r = -0.496). Unilateral IPG end-of-life generally led to subacute worsening of contralateral parkinsonism. In 25% of patients, there was also a worsening of axial symptoms leading to potential medical emergencies such as falls (10%), aspiration pneumonia (10%), or psychosis (5%). A close monitoring of patients and an anticipation of IPG replacement in the case of a low-battery signal are recommended.

Url:

http://www.hal.inserm.fr/inserm-00382268

DOI: 10.1002/mds.21726

Links to Exploration step

Hal:inserm-00382268

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lifetime of Itrel II pulse generators for subthalamic nucleus stimulation in Parkinson's disease.</title>
<author><name sortKey="Anheim, Mathieu" sort="Anheim, Mathieu" uniqKey="Anheim M" first="Mathieu" last="Anheim">Mathieu Anheim</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-14242" status="VALID"><orgName>Département de neurologie</orgName>
<desc><address><addrLine>Grenoble</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation><relation active="#struct-300071" type="direct"></relation>
<relation active="#struct-51016" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Fraix, Valerie" sort="Fraix, Valerie" uniqKey="Fraix V" first="Valérie" last="Fraix">Valérie Fraix</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-14242" status="VALID"><orgName>Département de neurologie</orgName>
<desc><address><addrLine>Grenoble</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation><relation active="#struct-300071" type="direct"></relation>
<relation active="#struct-51016" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Chabardes, Stephan" sort="Chabardes, Stephan" uniqKey="Chabardes S" first="Stéphan" last="Chabardès">Stéphan Chabardès</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-92131" status="VALID">  <orgName>Département de neurochirurgie</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
  <listRelation>    <relation active="#struct-51016" type="direct"></relation>
    <relation active="#struct-300071" type="direct"></relation>
  </listRelation>
<tutelles><tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Krack, Paul" sort="Krack, Paul" uniqKey="Krack P" first="Paul" last="Krack">Paul Krack</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-14242" status="VALID"><orgName>Département de neurologie</orgName>
<desc><address><addrLine>Grenoble</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation><relation active="#struct-300071" type="direct"></relation>
<relation active="#struct-51016" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Benabid, Alim Louis" sort="Benabid, Alim Louis" uniqKey="Benabid A" first="Alim-Louis" last="Benabid">Alim-Louis Benabid</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-92131" status="VALID">  <orgName>Département de neurochirurgie</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
  <listRelation>    <relation active="#struct-51016" type="direct"></relation>
    <relation active="#struct-300071" type="direct"></relation>
  </listRelation>
<tutelles><tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-14242" status="VALID"><orgName>Département de neurologie</orgName>
<desc><address><addrLine>Grenoble</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation><relation active="#struct-300071" type="direct"></relation>
<relation active="#struct-51016" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:inserm-00382268</idno>
<idno type="halId">inserm-00382268</idno>
<idno type="halUri">http://www.hal.inserm.fr/inserm-00382268</idno>
<idno type="url">http://www.hal.inserm.fr/inserm-00382268</idno>
<idno type="doi">10.1002/mds.21726</idno>
<date when="2007-12">2007-12</date>
<idno type="wicri:Area/Hal/Corpus">000632</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Lifetime of Itrel II pulse generators for subthalamic nucleus stimulation in Parkinson's disease.</title>
<author><name sortKey="Anheim, Mathieu" sort="Anheim, Mathieu" uniqKey="Anheim M" first="Mathieu" last="Anheim">Mathieu Anheim</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-14242" status="VALID"><orgName>Département de neurologie</orgName>
<desc><address><addrLine>Grenoble</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation><relation active="#struct-300071" type="direct"></relation>
<relation active="#struct-51016" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Fraix, Valerie" sort="Fraix, Valerie" uniqKey="Fraix V" first="Valérie" last="Fraix">Valérie Fraix</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-14242" status="VALID"><orgName>Département de neurologie</orgName>
<desc><address><addrLine>Grenoble</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation><relation active="#struct-300071" type="direct"></relation>
<relation active="#struct-51016" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Chabardes, Stephan" sort="Chabardes, Stephan" uniqKey="Chabardes S" first="Stéphan" last="Chabardès">Stéphan Chabardès</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-92131" status="VALID">  <orgName>Département de neurochirurgie</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
  <listRelation>    <relation active="#struct-51016" type="direct"></relation>
    <relation active="#struct-300071" type="direct"></relation>
  </listRelation>
<tutelles><tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Krack, Paul" sort="Krack, Paul" uniqKey="Krack P" first="Paul" last="Krack">Paul Krack</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-14242" status="VALID"><orgName>Département de neurologie</orgName>
<desc><address><addrLine>Grenoble</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation><relation active="#struct-300071" type="direct"></relation>
<relation active="#struct-51016" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Benabid, Alim Louis" sort="Benabid, Alim Louis" uniqKey="Benabid A" first="Alim-Louis" last="Benabid">Alim-Louis Benabid</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-92131" status="VALID">  <orgName>Département de neurochirurgie</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
  <listRelation>    <relation active="#struct-51016" type="direct"></relation>
    <relation active="#struct-300071" type="direct"></relation>
  </listRelation>
<tutelles><tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-14242" status="VALID"><orgName>Département de neurologie</orgName>
<desc><address><addrLine>Grenoble</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation><relation active="#struct-300071" type="direct"></relation>
<relation active="#struct-51016" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID">  <orgName>CHU Grenoble</orgName>
  <desc>    <address>      <country key="FR"></country>
    </address>
  </desc>
</org>
</tutelle>
<tutelle active="#struct-51016" type="direct"><org type="institution" xml:id="struct-51016" status="OLD">  <idno type="IdRef">026404796</idno>
  <orgName>Université Joseph Fourier - Grenoble 1</orgName>
  <orgName type="acronym">UJF</orgName>
  <date type="end">2015-12-31</date>
  <desc>    <address>      <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
      <country key="FR"></country>
    </address>
    <ref type="url">http://www.ujf-grenoble.fr/</ref>
  </desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
</analytic>
<idno type="DOI">10.1002/mds.21726</idno>
<series><title level="j">Movement Disorders</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date type="datePub">2007-12</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The efficacy of bilateral subthalamic nucleus (STN) stimulation in Parkinson's disease (PD) is well-established but little is known about the lifetime of implanted pulse generators (IPG). To investigate the lifetime of the bilaterally implanted Itrel II(R) (Medtronic, Minneapolis) pulse generator, the first 49 consecutive patients with PD having been operated on at our center for bilateral STN chronic stimulation were reviewed with noting of the stimulation parameters in use prior to IPG replacement. The mean electrical voltage was 3.2 +/- 0.3 V, mean pulse width was 65 +/- 10 mus, and mean frequency was 145 +/- 16 Hz. Replacement of an IPG was anticipated in 25% due to unilateral low-battery signaling, or end of life. In either case, replacement of the contralateral IPG was undertaken simultaneously. The mean IPG lifetime was 83 +/- 14 [40-113] months. The IPG lifetime correlated with the total electrical energy delivered (P = 0.002, r = -0.496). Unilateral IPG end-of-life generally led to subacute worsening of contralateral parkinsonism. In 25% of patients, there was also a worsening of axial symptoms leading to potential medical emergencies such as falls (10%), aspiration pneumonia (10%), or psychosis (5%). A close monitoring of patients and an anticipation of IPG replacement in the case of a low-battery signal are recommended.</div>
</front>
</TEI>
<hal api="V3">          <titleStmt>            <title xml:lang="en">Lifetime of Itrel II pulse generators for subthalamic nucleus stimulation in Parkinson's disease.</title>
            <author role="aut">              <persName>                <forename type="first">Mathieu</forename>
                <surname>Anheim</surname>
              </persName>
              <idno type="halauthorid">228212</idno>
              <affiliation ref="#struct-14242"></affiliation>
            </author>
            <author role="aut">              <persName>                <forename type="first">Valérie</forename>
                <surname>Fraix</surname>
              </persName>
              <idno type="halauthorid">296411</idno>
              <affiliation ref="#struct-14242"></affiliation>
            </author>
            <author role="aut">              <persName>                <forename type="first">Stéphan</forename>
                <surname>Chabardès</surname>
              </persName>
              <idno type="halauthorid">402664</idno>
              <affiliation ref="#struct-92131"></affiliation>
            </author>
            <author role="aut">              <persName>                <forename type="first">Paul</forename>
                <surname>Krack</surname>
              </persName>
              <idno type="halauthorid">296412</idno>
              <affiliation ref="#struct-14242"></affiliation>
            </author>
            <author role="aut">              <persName>                <forename type="first">Alim-Louis</forename>
                <surname>Benabid</surname>
              </persName>
              <idno type="halauthorid">296407</idno>
              <affiliation ref="#struct-92131"></affiliation>
            </author>
            <author role="aut">              <persName>                <forename type="first">Pierre</forename>
                <surname>Pollak</surname>
              </persName>
              <idno type="halauthorid">233619</idno>
              <affiliation ref="#struct-14242"></affiliation>
            </author>
            <editor role="depositor">              <persName>                <forename>Jean-Paul</forename>
                <surname>Issartel</surname>
              </persName>
              <email type="md5">cd02e0e31e31c3aad10ee791497a6afd</email>
              <email type="domain">ujf-grenoble.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>            <edition n="v1" type="current">              <date type="whenSubmitted">2009-05-07 16:23:12</date>
              <date type="whenModified">2009-05-07 17:03:50</date>
              <date type="whenReleased">2009-05-07 17:03:50</date>
              <date type="whenProduced">2007-12</date>
            </edition>
            <respStmt>              <resp>contributor</resp>
              <name key="140381">                <persName>                  <forename>Jean-Paul</forename>
                  <surname>Issartel</surname>
                </persName>
                <email type="md5">cd02e0e31e31c3aad10ee791497a6afd</email>
                <email type="domain">ujf-grenoble.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>            <distributor>CCSD</distributor>
            <idno type="halId">inserm-00382268</idno>
            <idno type="halUri">http://www.hal.inserm.fr/inserm-00382268</idno>
            <idno type="halBibtex">anheim:inserm-00382268</idno>
            <idno type="halRefHtml">Movement Disorders, Wiley, 2007, 22 (16), pp.2436-9. <10.1002/mds.21726></idno>
            <idno type="halRef">Movement Disorders, Wiley, 2007, 22 (16), pp.2436-9. <10.1002/mds.21726></idno>
          </publicationStmt>
          <seriesStmt>            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="UNIV-GRENOBLE1" p="UGA">Université Joseph Fourier - Grenoble I</idno>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
          </seriesStmt>
          <notesStmt>            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>            <biblStruct>              <analytic>                <title xml:lang="en">Lifetime of Itrel II pulse generators for subthalamic nucleus stimulation in Parkinson's disease.</title>
                <author role="aut">                  <persName>                    <forename type="first">Mathieu</forename>
                    <surname>Anheim</surname>
                  </persName>
                  <idno type="halauthorid">228212</idno>
                  <affiliation ref="#struct-14242"></affiliation>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Valérie</forename>
                    <surname>Fraix</surname>
                  </persName>
                  <idno type="halauthorid">296411</idno>
                  <affiliation ref="#struct-14242"></affiliation>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Stéphan</forename>
                    <surname>Chabardès</surname>
                  </persName>
                  <idno type="halauthorid">402664</idno>
                  <affiliation ref="#struct-92131"></affiliation>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Paul</forename>
                    <surname>Krack</surname>
                  </persName>
                  <idno type="halauthorid">296412</idno>
                  <affiliation ref="#struct-14242"></affiliation>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Alim-Louis</forename>
                    <surname>Benabid</surname>
                  </persName>
                  <idno type="halauthorid">296407</idno>
                  <affiliation ref="#struct-92131"></affiliation>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Pierre</forename>
                    <surname>Pollak</surname>
                  </persName>
                  <idno type="halauthorid">233619</idno>
                  <affiliation ref="#struct-14242"></affiliation>
                </author>
              </analytic>
              <monogr>                <idno type="halJournalId" status="VALID">17211</idno>
                <idno type="issn">0885-3185</idno>
                <idno type="eissn">1531-8257</idno>
                <title level="j">Movement Disorders</title>
                <imprint>                  <publisher>Wiley</publisher>
                  <biblScope unit="volume">22</biblScope>
                  <biblScope unit="issue">16</biblScope>
                  <biblScope unit="pp">2436-9</biblScope>
                  <date type="datePub">2007-12</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1002/mds.21726</idno>
              <idno type="pubmed">17960811</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>            <langUsage>              <language ident="en">English</language>
            </langUsage>
            <textClass>              <classCode scheme="mesh">Aged</classCode>
              <classCode scheme="mesh">Deep Brain Stimulation</classCode>
              <classCode scheme="mesh">Subthalamic Nucleus</classCode>
              <classCode scheme="mesh">Electrodes, Implanted</classCode>
              <classCode scheme="mesh">Female</classCode>
              <classCode scheme="mesh">Follow-Up Studies</classCode>
              <classCode scheme="mesh">Humans</classCode>
              <classCode scheme="mesh">Male</classCode>
              <classCode scheme="mesh">Middle Aged</classCode>
              <classCode scheme="mesh">Parkinson Disease</classCode>
              <classCode scheme="mesh">Retrospective Studies</classCode>
              <classCode scheme="halDomain" n="sdv.neu">Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">The efficacy of bilateral subthalamic nucleus (STN) stimulation in Parkinson's disease (PD) is well-established but little is known about the lifetime of implanted pulse generators (IPG). To investigate the lifetime of the bilaterally implanted Itrel II(R) (Medtronic, Minneapolis) pulse generator, the first 49 consecutive patients with PD having been operated on at our center for bilateral STN chronic stimulation were reviewed with noting of the stimulation parameters in use prior to IPG replacement. The mean electrical voltage was 3.2 +/- 0.3 V, mean pulse width was 65 +/- 10 mus, and mean frequency was 145 +/- 16 Hz. Replacement of an IPG was anticipated in 25% due to unilateral low-battery signaling, or end of life. In either case, replacement of the contralateral IPG was undertaken simultaneously. The mean IPG lifetime was 83 +/- 14 [40-113] months. The IPG lifetime correlated with the total electrical energy delivered (P = 0.002, r = -0.496). Unilateral IPG end-of-life generally led to subacute worsening of contralateral parkinsonism. In 25% of patients, there was also a worsening of axial symptoms leading to potential medical emergencies such as falls (10%), aspiration pneumonia (10%), or psychosis (5%). A close monitoring of patients and an anticipation of IPG replacement in the case of a low-battery signal are recommended.</abstract>
            <particDesc>              <org type="consortium">Collaboration</org>
            </particDesc>
          </profileDesc>
        </hal>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Hal/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000632 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Hal/Corpus/biblio.hfd -nk 000632 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    ParkinsonFranceV1
   |flux=    Hal
   |étape=   Corpus
   |type=    RBID
   |clé=     Hal:inserm-00382268
   |texte=   Lifetime of Itrel II pulse generators for subthalamic nucleus stimulation in Parkinson's disease.
}}

This area was generated with Dilib version V0.6.29.
Data generation: Wed May 17 19:46:39 2017. Site generation: Mon Mar 4 15:48:15 2024

	La maladie de Parkinson en France (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

La maladie de Parkinson en France (serveur d'exploration)

Lifetime of Itrel II pulse generators for subthalamic nucleus stimulation in Parkinson's disease.

Lifetime of Itrel II pulse generators for subthalamic nucleus stimulation in Parkinson's disease.

Source :

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri