Ident. | Authors (with country if any) | Title |
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000305 (2003) |
Stephen J. Crocker [Canada] ; Patrice D. Smith ; Vernice Jackson-Lewis ; Wiplore R. Lamba ; Shawn P. Hayley ; Erich Grimm ; Steve M. Callaghan ; Ruth S. Slack ; Edon Melloni ; Serge Przedborski ; George S. Robertson ; Hymie Anisman ; Zul Merali ; David S. Park | Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease. |
000365 (2003) |
Patrice D. Smith [Canada] ; Stephen J. Crocker [Canada] ; Vernice Jackson-Lewis ; Kelly L. Jordan-Sciutto [États-Unis] ; Shawn Hayley [Canada] ; Matthew P. Mount [Canada] ; Michael J. O'Hare [Canada] ; Steven Callaghan [Canada] ; Ruth S. Slack [Canada] ; Serge Przedborski [États-Unis] ; Hymie Anisman [Canada] ; David S. Park [Canada] | Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease |
000451 (2004) |
Patrice D. Smith [Canada] ; Michael J. O'Hare ; David S. Park | CDKs: taking on a role as mediators of dopaminergic loss in Parkinson's disease. |
000481 (2004) |
Suneil K. Kalia [Canada] ; Sang Lee ; Patrice D. Smith ; Li Liu ; Stephen J. Crocker ; Thorhildur E. Thorarinsdottir ; John R. Glover ; Edward A. Fon ; David S. Park ; Andres M. Lozano | BAG5 inhibits parkin and enhances dopaminergic neuron degeneration. |
000519 (2005) |
Raymond H. Kim [Canada] ; Patrice D. Smith [Canada] ; Hossein Aleyasin [Canada] ; Shawn Hayley [Canada] ; Matthew P. Mount [Canada] ; Scott Pownall [Canada] ; Andrew Wakeham [Canada] ; Annick J. You-Ten [Canada] ; Suneil K. Kalia [Canada] ; Patrick Horne [Canada] ; David Westaway [Canada] ; Andres M. Lozano [Canada] ; Hymie Anisman [Canada] ; David S. Park [Canada] ; Tak W. Mak [Canada] | Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress |
000746 (2007) |
Matthew P. Mount [Canada] ; Arman Lira ; David Grimes ; Patrice D. Smith ; Sylvie Faucher ; Ruth Slack ; Hymie Anisman ; Shawn Hayley ; David S. Park | Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons. |
000785 (2007) |
Dianbo Qu [Canada] ; Juliet Rashidian ; Matthew P. Mount ; Hossein Aleyasin ; Mohammad Parsanejad ; Arman Lira ; Emdadul Haque ; Yi Zhang ; Steve Callaghan ; Mireille Daigle ; Maxime W C. Rousseaux ; Ruth S. Slack ; Paul R. Albert ; Inez Vincent ; John M. Woulfe ; David S. Park | Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease. |
000840 (2007) |
Hossein Aleyasin [Canada] ; Maxime W. C. Rousseaux [Canada] ; Maryam Phillips [Canada] ; Raymond H. Kim [Canada] ; Ross J. Bland [États-Unis] ; Steve Callaghan [Canada] ; Ruth S. Slack [Canada] ; Matthew J. During [États-Unis] ; Tak W. Mak [Canada] ; David S. Park [Canada] | The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage |
000866 (2008) |
M. Emdadul Haque [Canada] ; Kelly J. Thomas [États-Unis] ; Cheryl D'Souza [Canada] ; Steve Callaghan [Canada] ; Tohru Kitada [États-Unis] ; Ruth S. Slack [Canada] ; Paul Fraser [Canada] ; Mark R. Cookson [États-Unis] ; Anurag Tandon [Canada] ; David S. Park [Canada] | Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP |
000A58 (2009) |
Isabella Irrcher [Canada] ; David S. Park | Parkinson's disease: to live or die by autophagy. |
000B33 (2009) |
Katerina Venderova [Canada] ; Ghassan Kabbach ; Elizabeth Abdel-Messih ; Yi Zhang ; Robin J. Parks ; Yuzuru Imai ; Stephan Gehrke ; Johnny Ngsee ; Matthew J. Lavoie ; Ruth S. Slack ; Yong Rao ; Zhuohua Zhang ; Bingwei Lu ; M Emdadul Haque ; David S. Park | Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease. |
000C13 (2010) |
Hossein Aleyasin [Canada] ; Maxime W. C. Rousseaux [Canada] ; Paul C. Marcogliese [Canada] ; Sarah J. Hewitt [Canada] ; Isabella Irrcher [Canada] ; Alvin P. Joselin [Canada] ; Mohammad Parsanejad [Canada] ; Raymond H. Kim [Canada] ; Patrizia Rizzu [Pays-Bas] ; Steve M. Callaghan [Canada] ; Ruth S. Slack [Canada] ; Tak W. Mak [Canada] ; David S. Park [Canada, Corée du Sud] | DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway |
000C32 (2010) |
Subhas C. Biswas [États-Unis] ; Yi Zhang [Canada] ; Grace Iyirhiaro [Canada] ; Ryan T. Willett [États-Unis] ; Yasmilde Rodriguez Gonzalez [Canada] ; Sean P. Cregan ; Ruth S. Slack [Canada] ; David S. Park [Canada] ; Lloyd A. Greene [États-Unis] | SERTAD1 PLAYS AN ESSENTIAL ROLE IN DEVELOPMENTAL AND PATHOLOGICAL NEURON DEATH |
000E77 (2011) |
Mansoureh Hakimi [Canada] ; Thirumahal Selvanantham [Canada] ; Erika Swinton [Canada] ; Ruth F. Padmore [Canada] ; Youren Tong [États-Unis] ; Ghassan Kabbach [Canada] ; Katerina Venderova [Canada] ; Stephen E. Girardin [Canada] ; Dennis E. Bulman [Canada] ; Clemens R. Scherzer [États-Unis] ; Matthew J. Lavoie [États-Unis] ; Denis Gris [États-Unis] ; David S. Park [Canada] ; Jonathan B. Angel [Canada] ; Jie Shen [États-Unis] ; Dana J. Philpott [Canada] ; Michael G. Schlossmacher [Canada] | Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures |
000F02 (2011) |
Arman Lira ; Jerzy Kulczycki ; Ruth Slack ; Hymie Anisman ; David S. Park | Involvement of the Fcγ Receptor in a Chronic N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Dopaminergic Loss* |
001002 (2012) |
Maria Xilouri [Grèce] ; Elli Kyratzi ; Pothitos M. Pitychoutis ; Zoi Papadopoulou-Daifoti ; Celine Perier ; Miquel Vila ; Matina Maniati ; Ayse Ulusoy ; Deniz Kirik ; David S. Park ; Keiji Wada ; Leonidas Stefanis | Selective neuroprotective effects of the S18Y polymorphic variant of UCH-L1 in the dopaminergic system. |
001069 (2012) |
Andrew W. Greene [Canada] ; Karl Grenier ; Miguel A. Aguileta ; Stephanie Muise ; Rasoul Farazifard ; M Emdadul Haque ; Heidi M. Mcbride ; David S. Park ; Edward A. Fon | Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. |
001126 (2012) |
M. Emdadul Haque ; Matthew P. Mount ; Farzaneh Safarpour ; Elizabeth Abdel-Messih ; Steve Callaghan ; Chantal Mazerolle ; Tohru Kitada ; Ruth S. Slack ; Valerie Wallace ; Jie Shen ; Hymie Anisman ; David S. Park | Inactivation of Pink1 Gene in Vivo Sensitizes Dopamine-producing Neurons to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and Can Be Rescued by Autosomal Recessive Parkinson Disease Genes, Parkin or DJ-1 |
001223 (2012) |
Katerina Venderova [États-Unis] ; David S. Park [Canada] | Programmed Cell Death in Parkinson's Disease |
001264 (2012) |
Maxime W. C. Rousseaux ; Paul C. Marcogliese ; Dianbo Qu ; Sarah J. Hewitt ; Sarah Seang ; Raymond H. Kim ; Ruth S. Slack ; Michael G. Schlossmacher ; Diane C. Lagace ; Tak W. Mak ; David S. Park [Corée du Sud] | Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease |
001419 (2013) |
Matthew P. Mount ; Yi Zhang ; Mandana Amini ; Steve Callaghan ; Jerzy Kulczycki ; Zixu Mao ; Ruth S. Slack ; Hymie Anisman ; David S. Park | Perturbation of Transcription Factor Nur77 Expression Mediated by Myocyte Enhancer Factor 2D (MEF2D) Regulates Dopaminergic Neuron Loss in Response to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)* |