PandemieGrippaleV1, PubMed, Curation, bibRecord, 000737

Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses.

Identifieur interne : 000737 ( PubMed/Curation ); précédent : 000736; suivant : 000738

Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses.

Source :

PLoS pathogens [ 1553-7374 ] ; 2014.

RBID : pubmed:25411973

Descripteurs français

KwdFr :
- Animaux, Cellules rénales canines Madin-Darby, Chiens, Chine, Données de séquences moléculaires, Furets, Grippe chez les oiseaux (génétique), Grippe chez les oiseaux (transmission), Grippe humaine (génétique), Grippe humaine (transmission), Humains, Maladies de la volaille (génétique), Maladies de la volaille (transmission), Maladies de la volaille (virologie), Poulets, Sous-type H9N2 du virus de la grippe A (génétique), Sous-type H9N2 du virus de la grippe A (isolement et purification), Sous-type H9N2 du virus de la grippe A (pathogénicité), Séquence nucléotidique, Variation génétique.
MESH :
- génétique : Grippe chez les oiseaux, Grippe humaine, Maladies de la volaille, Sous-type H9N2 du virus de la grippe A.
- isolement et purification : Sous-type H9N2 du virus de la grippe A.
- pathogénicité : Sous-type H9N2 du virus de la grippe A.
- virologie : Maladies de la volaille.
- Animaux, Cellules rénales canines Madin-Darby, Chiens, Chine, Données de séquences moléculaires, Furets, Grippe chez les oiseaux, Grippe humaine, Humains, Maladies de la volaille, Poulets, Séquence nucléotidique, Variation génétique.
Wicri :
- geographic : République populaire de Chine.

English descriptors

KwdEn :
- Animals, Base Sequence, Chickens, China, Dogs, Ferrets, Genetic Variation, Humans, Influenza A Virus, H9N2 Subtype (genetics), Influenza A Virus, H9N2 Subtype (isolation & purification), Influenza A Virus, H9N2 Subtype (pathogenicity), Influenza in Birds (genetics), Influenza in Birds (transmission), Influenza, Human (genetics), Influenza, Human (transmission), Madin Darby Canine Kidney Cells, Molecular Sequence Data, Poultry Diseases (genetics), Poultry Diseases (transmission), Poultry Diseases (virology).
MESH :
- geographic : China.
- genetics : Influenza A Virus, H9N2 Subtype, Influenza in Birds, Influenza, Human, Poultry Diseases.
- isolation & purification : Influenza A Virus, H9N2 Subtype.
- pathogenicity : Influenza A Virus, H9N2 Subtype.
- transmission : Influenza in Birds, Influenza, Human, Poultry Diseases.
- virology : Poultry Diseases.
- Animals, Base Sequence, Chickens, Dogs, Ferrets, Genetic Variation, Humans, Madin Darby Canine Kidney Cells, Molecular Sequence Data.

Abstract

H9N2 subtype influenza viruses have been detected in different species of wild birds and domestic poultry in many countries for several decades. Because these viruses are of low pathogenicity in poultry, their eradication is not a priority for animal disease control in many countries, which has allowed them to continue to evolve and spread. Here, we characterized the genetic variation, receptor-binding specificity, replication capability, and transmission in mammals of a series of H9N2 influenza viruses that were detected in live poultry markets in southern China between 2009 and 2013. Thirty-five viruses represented 17 genotypes on the basis of genomic diversity, and one specific "internal-gene-combination" predominated among the H9N2 viruses. This gene combination was also present in the H7N9 and H10N8 viruses that have infected humans in China. All of the 35 viruses preferentially bound to the human-like receptor, although two also retained the ability to bind to the avian-like receptor. Six of nine viruses tested were transmissible in ferrets by respiratory droplet; two were highly transmissible. Some H9N2 viruses readily acquired the 627K or 701N mutation in their PB2 gene upon infection of ferrets, further enhancing their virulence and transmission in mammals. Our study indicates that the widespread dissemination of H9N2 viruses poses a threat to human health not only because of the potential of these viruses to cause an influenza pandemic, but also because they can function as "vehicles" to deliver different subtypes of influenza viruses from avian species to humans.

DOI: 10.1371/journal.ppat.1004508
PubMed: 25411973

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000737

Links to Exploration step

pubmed:25411973

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses.</title>
<author><name sortKey="Li, Xuyong" sort="Li, Xuyong" uniqKey="Li X" first="Xuyong" last="Li">Xuyong Li</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shi, Jianzhong" sort="Shi, Jianzhong" uniqKey="Shi J" first="Jianzhong" last="Shi">Jianzhong Shi</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Guo, Jing" sort="Guo, Jing" uniqKey="Guo J" first="Jing" last="Guo">Jing Guo</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deng, Guohua" sort="Deng, Guohua" uniqKey="Deng G" first="Guohua" last="Deng">Guohua Deng</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhang, Qianyi" sort="Zhang, Qianyi" uniqKey="Zhang Q" first="Qianyi" last="Zhang">Qianyi Zhang</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Jinliang" sort="Wang, Jinliang" uniqKey="Wang J" first="Jinliang" last="Wang">Jinliang Wang</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="He, Xijun" sort="He, Xijun" uniqKey="He X" first="Xijun" last="He">Xijun He</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Kaicheng" sort="Wang, Kaicheng" uniqKey="Wang K" first="Kaicheng" last="Wang">Kaicheng Wang</name>
<affiliation wicri:level="1"><nlm:affiliation>Laboratory of Avian Disease Surveillance, China Animal Health and Epidemiology Center, Qingdao, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Laboratory of Avian Disease Surveillance, China Animal Health and Epidemiology Center, Qingdao</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chen, Jiming" sort="Chen, Jiming" uniqKey="Chen J" first="Jiming" last="Chen">Jiming Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>Laboratory of Avian Disease Surveillance, China Animal Health and Epidemiology Center, Qingdao, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Laboratory of Avian Disease Surveillance, China Animal Health and Epidemiology Center, Qingdao</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, Yuanyuan" sort="Li, Yuanyuan" uniqKey="Li Y" first="Yuanyuan" last="Li">Yuanyuan Li</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fan, Jun" sort="Fan, Jun" uniqKey="Fan J" first="Jun" last="Fan">Jun Fan</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kong, Huiui" sort="Kong, Huiui" uniqKey="Kong H" first="Huiui" last="Kong">Huiui Kong</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gu, Chunyang" sort="Gu, Chunyang" uniqKey="Gu C" first="Chunyang" last="Gu">Chunyang Gu</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Guan, Yuantao" sort="Guan, Yuantao" uniqKey="Guan Y" first="Yuantao" last="Guan">Yuantao Guan</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Suzuki, Yasuo" sort="Suzuki, Yasuo" uniqKey="Suzuki Y" first="Yasuo" last="Suzuki">Yasuo Suzuki</name>
<affiliation wicri:level="1"><nlm:affiliation>College of Life and Health Sciences, Chubu University, Aichi, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>College of Life and Health Sciences, Chubu University, Aichi</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kawaoka, Yoshihiro" sort="Kawaoka, Yoshihiro" uniqKey="Kawaoka Y" first="Yoshihiro" last="Kawaoka">Yoshihiro Kawaoka</name>
<affiliation wicri:level="1"><nlm:affiliation>International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liu, Liling" sort="Liu, Liling" uniqKey="Liu L" first="Liling" last="Liu">Liling Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jiang, Yongping" sort="Jiang, Yongping" uniqKey="Jiang Y" first="Yongping" last="Jiang">Yongping Jiang</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tian, Guobin" sort="Tian, Guobin" uniqKey="Tian G" first="Guobin" last="Tian">Guobin Tian</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, Yanbing" sort="Li, Yanbing" uniqKey="Li Y" first="Yanbing" last="Li">Yanbing Li</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bu, Zhigao" sort="Bu, Zhigao" uniqKey="Bu Z" first="Zhigao" last="Bu">Zhigao Bu</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chen, Hualan" sort="Chen, Hualan" uniqKey="Chen H" first="Hualan" last="Chen">Hualan Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2014">2014</date>
<idno type="RBID">pubmed:25411973</idno>
<idno type="pmid">25411973</idno>
<idno type="doi">10.1371/journal.ppat.1004508</idno>
<idno type="wicri:Area/PubMed/Corpus">000737</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000737</idno>
<idno type="wicri:Area/PubMed/Curation">000737</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000737</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses.</title>
<author><name sortKey="Li, Xuyong" sort="Li, Xuyong" uniqKey="Li X" first="Xuyong" last="Li">Xuyong Li</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shi, Jianzhong" sort="Shi, Jianzhong" uniqKey="Shi J" first="Jianzhong" last="Shi">Jianzhong Shi</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Guo, Jing" sort="Guo, Jing" uniqKey="Guo J" first="Jing" last="Guo">Jing Guo</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deng, Guohua" sort="Deng, Guohua" uniqKey="Deng G" first="Guohua" last="Deng">Guohua Deng</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhang, Qianyi" sort="Zhang, Qianyi" uniqKey="Zhang Q" first="Qianyi" last="Zhang">Qianyi Zhang</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Jinliang" sort="Wang, Jinliang" uniqKey="Wang J" first="Jinliang" last="Wang">Jinliang Wang</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="He, Xijun" sort="He, Xijun" uniqKey="He X" first="Xijun" last="He">Xijun He</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Kaicheng" sort="Wang, Kaicheng" uniqKey="Wang K" first="Kaicheng" last="Wang">Kaicheng Wang</name>
<affiliation wicri:level="1"><nlm:affiliation>Laboratory of Avian Disease Surveillance, China Animal Health and Epidemiology Center, Qingdao, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Laboratory of Avian Disease Surveillance, China Animal Health and Epidemiology Center, Qingdao</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chen, Jiming" sort="Chen, Jiming" uniqKey="Chen J" first="Jiming" last="Chen">Jiming Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>Laboratory of Avian Disease Surveillance, China Animal Health and Epidemiology Center, Qingdao, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Laboratory of Avian Disease Surveillance, China Animal Health and Epidemiology Center, Qingdao</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, Yuanyuan" sort="Li, Yuanyuan" uniqKey="Li Y" first="Yuanyuan" last="Li">Yuanyuan Li</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fan, Jun" sort="Fan, Jun" uniqKey="Fan J" first="Jun" last="Fan">Jun Fan</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kong, Huiui" sort="Kong, Huiui" uniqKey="Kong H" first="Huiui" last="Kong">Huiui Kong</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gu, Chunyang" sort="Gu, Chunyang" uniqKey="Gu C" first="Chunyang" last="Gu">Chunyang Gu</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Guan, Yuantao" sort="Guan, Yuantao" uniqKey="Guan Y" first="Yuantao" last="Guan">Yuantao Guan</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Suzuki, Yasuo" sort="Suzuki, Yasuo" uniqKey="Suzuki Y" first="Yasuo" last="Suzuki">Yasuo Suzuki</name>
<affiliation wicri:level="1"><nlm:affiliation>College of Life and Health Sciences, Chubu University, Aichi, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>College of Life and Health Sciences, Chubu University, Aichi</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kawaoka, Yoshihiro" sort="Kawaoka, Yoshihiro" uniqKey="Kawaoka Y" first="Yoshihiro" last="Kawaoka">Yoshihiro Kawaoka</name>
<affiliation wicri:level="1"><nlm:affiliation>International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liu, Liling" sort="Liu, Liling" uniqKey="Liu L" first="Liling" last="Liu">Liling Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jiang, Yongping" sort="Jiang, Yongping" uniqKey="Jiang Y" first="Yongping" last="Jiang">Yongping Jiang</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tian, Guobin" sort="Tian, Guobin" uniqKey="Tian G" first="Guobin" last="Tian">Guobin Tian</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, Yanbing" sort="Li, Yanbing" uniqKey="Li Y" first="Yanbing" last="Li">Yanbing Li</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bu, Zhigao" sort="Bu, Zhigao" uniqKey="Bu Z" first="Zhigao" last="Bu">Zhigao Bu</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chen, Hualan" sort="Chen, Hualan" uniqKey="Chen H" first="Hualan" last="Chen">Hualan Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS pathogens</title>
<idno type="eISSN">1553-7374</idno>
<imprint><date when="2014" type="published">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Base Sequence</term>
<term>Chickens</term>
<term>China</term>
<term>Dogs</term>
<term>Ferrets</term>
<term>Genetic Variation</term>
<term>Humans</term>
<term>Influenza A Virus, H9N2 Subtype (genetics)</term>
<term>Influenza A Virus, H9N2 Subtype (isolation & purification)</term>
<term>Influenza A Virus, H9N2 Subtype (pathogenicity)</term>
<term>Influenza in Birds (genetics)</term>
<term>Influenza in Birds (transmission)</term>
<term>Influenza, Human (genetics)</term>
<term>Influenza, Human (transmission)</term>
<term>Madin Darby Canine Kidney Cells</term>
<term>Molecular Sequence Data</term>
<term>Poultry Diseases (genetics)</term>
<term>Poultry Diseases (transmission)</term>
<term>Poultry Diseases (virology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Cellules rénales canines Madin-Darby</term>
<term>Chiens</term>
<term>Chine</term>
<term>Données de séquences moléculaires</term>
<term>Furets</term>
<term>Grippe chez les oiseaux (génétique)</term>
<term>Grippe chez les oiseaux (transmission)</term>
<term>Grippe humaine (génétique)</term>
<term>Grippe humaine (transmission)</term>
<term>Humains</term>
<term>Maladies de la volaille (génétique)</term>
<term>Maladies de la volaille (transmission)</term>
<term>Maladies de la volaille (virologie)</term>
<term>Poulets</term>
<term>Sous-type H9N2 du virus de la grippe A (génétique)</term>
<term>Sous-type H9N2 du virus de la grippe A (isolement et purification)</term>
<term>Sous-type H9N2 du virus de la grippe A (pathogénicité)</term>
<term>Séquence nucléotidique</term>
<term>Variation génétique</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>China</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A Virus, H9N2 Subtype</term>
<term>Influenza in Birds</term>
<term>Influenza, Human</term>
<term>Poultry Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Grippe chez les oiseaux</term>
<term>Grippe humaine</term>
<term>Maladies de la volaille</term>
<term>Sous-type H9N2 du virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H9N2 Subtype</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Sous-type H9N2 du virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Influenza A Virus, H9N2 Subtype</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Sous-type H9N2 du virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Influenza in Birds</term>
<term>Influenza, Human</term>
<term>Poultry Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Maladies de la volaille</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Poultry Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Base Sequence</term>
<term>Chickens</term>
<term>Dogs</term>
<term>Ferrets</term>
<term>Genetic Variation</term>
<term>Humans</term>
<term>Madin Darby Canine Kidney Cells</term>
<term>Molecular Sequence Data</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Cellules rénales canines Madin-Darby</term>
<term>Chiens</term>
<term>Chine</term>
<term>Données de séquences moléculaires</term>
<term>Furets</term>
<term>Grippe chez les oiseaux</term>
<term>Grippe humaine</term>
<term>Humains</term>
<term>Maladies de la volaille</term>
<term>Poulets</term>
<term>Séquence nucléotidique</term>
<term>Variation génétique</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>République populaire de Chine</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">H9N2 subtype influenza viruses have been detected in different species of wild birds and domestic poultry in many countries for several decades. Because these viruses are of low pathogenicity in poultry, their eradication is not a priority for animal disease control in many countries, which has allowed them to continue to evolve and spread. Here, we characterized the genetic variation, receptor-binding specificity, replication capability, and transmission in mammals of a series of H9N2 influenza viruses that were detected in live poultry markets in southern China between 2009 and 2013. Thirty-five viruses represented 17 genotypes on the basis of genomic diversity, and one specific "internal-gene-combination" predominated among the H9N2 viruses. This gene combination was also present in the H7N9 and H10N8 viruses that have infected humans in China. All of the 35 viruses preferentially bound to the human-like receptor, although two also retained the ability to bind to the avian-like receptor. Six of nine viruses tested were transmissible in ferrets by respiratory droplet; two were highly transmissible. Some H9N2 viruses readily acquired the 627K or 701N mutation in their PB2 gene upon infection of ferrets, further enhancing their virulence and transmission in mammals. Our study indicates that the widespread dissemination of H9N2 viruses poses a threat to human health not only because of the potential of these viruses to cause an influenza pandemic, but also because they can function as "vehicles" to deliver different subtypes of influenza viruses from avian species to humans. </div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25411973</PMID>
<DateCompleted><Year>2015</Year>
<Month>10</Month>
<Day>13</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1553-7374</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>10</Volume>
<Issue>11</Issue>
<PubDate><Year>2014</Year>
<Month>Nov</Month>
</PubDate>
</JournalIssue>
<Title>PLoS pathogens</Title>
<ISOAbbreviation>PLoS Pathog.</ISOAbbreviation>
</Journal>
<ArticleTitle>Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses.</ArticleTitle>
<Pagination><MedlinePgn>e1004508</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.ppat.1004508</ELocationID>
<Abstract><AbstractText>H9N2 subtype influenza viruses have been detected in different species of wild birds and domestic poultry in many countries for several decades. Because these viruses are of low pathogenicity in poultry, their eradication is not a priority for animal disease control in many countries, which has allowed them to continue to evolve and spread. Here, we characterized the genetic variation, receptor-binding specificity, replication capability, and transmission in mammals of a series of H9N2 influenza viruses that were detected in live poultry markets in southern China between 2009 and 2013. Thirty-five viruses represented 17 genotypes on the basis of genomic diversity, and one specific "internal-gene-combination" predominated among the H9N2 viruses. This gene combination was also present in the H7N9 and H10N8 viruses that have infected humans in China. All of the 35 viruses preferentially bound to the human-like receptor, although two also retained the ability to bind to the avian-like receptor. Six of nine viruses tested were transmissible in ferrets by respiratory droplet; two were highly transmissible. Some H9N2 viruses readily acquired the 627K or 701N mutation in their PB2 gene upon infection of ferrets, further enhancing their virulence and transmission in mammals. Our study indicates that the widespread dissemination of H9N2 viruses poses a threat to human health not only because of the potential of these viruses to cause an influenza pandemic, but also because they can function as "vehicles" to deliver different subtypes of influenza viruses from avian species to humans. </AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Xuyong</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Shi</LastName>
<ForeName>Jianzhong</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Guo</LastName>
<ForeName>Jing</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Deng</LastName>
<ForeName>Guohua</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Qianyi</ForeName>
<Initials>Q</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Jinliang</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>He</LastName>
<ForeName>Xijun</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Kaicheng</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Laboratory of Avian Disease Surveillance, China Animal Health and Epidemiology Center, Qingdao, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Jiming</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Laboratory of Avian Disease Surveillance, China Animal Health and Epidemiology Center, Qingdao, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Yuanyuan</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fan</LastName>
<ForeName>Jun</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kong</LastName>
<ForeName>Huiui</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gu</LastName>
<ForeName>Chunyang</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Guan</LastName>
<ForeName>Yuantao</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Suzuki</LastName>
<ForeName>Yasuo</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>College of Life and Health Sciences, Chubu University, Aichi, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kawaoka</LastName>
<ForeName>Yoshihiro</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Liling</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jiang</LastName>
<ForeName>Yongping</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tian</LastName>
<ForeName>Guobin</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Yanbing</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bu</LastName>
<ForeName>Zhigao</ForeName>
<Initials>Z</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Hualan</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<DataBankList CompleteYN="Y"><DataBank><DataBankName>GENBANK</DataBankName>
<AccessionNumberList><AccessionNumber>KM113042</AccessionNumber>
<AccessionNumber>KM113043</AccessionNumber>
<AccessionNumber>KM113044</AccessionNumber>
<AccessionNumber>KM113045</AccessionNumber>
<AccessionNumber>KM113046</AccessionNumber>
<AccessionNumber>KM113047</AccessionNumber>
<AccessionNumber>KM113048</AccessionNumber>
<AccessionNumber>KM113049</AccessionNumber>
<AccessionNumber>KM113050</AccessionNumber>
<AccessionNumber>KM113051</AccessionNumber>
<AccessionNumber>KM113052</AccessionNumber>
<AccessionNumber>KM113053</AccessionNumber>
<AccessionNumber>KM113054</AccessionNumber>
<AccessionNumber>KM113055</AccessionNumber>
<AccessionNumber>KM113056</AccessionNumber>
<AccessionNumber>KM113057</AccessionNumber>
<AccessionNumber>KM113058</AccessionNumber>
<AccessionNumber>KM113059</AccessionNumber>
<AccessionNumber>KM113060</AccessionNumber>
<AccessionNumber>KM113061</AccessionNumber>
<AccessionNumber>KM113062</AccessionNumber>
<AccessionNumber>KM113063</AccessionNumber>
<AccessionNumber>KM113064</AccessionNumber>
<AccessionNumber>KM113065</AccessionNumber>
<AccessionNumber>KM113066</AccessionNumber>
<AccessionNumber>KM113067</AccessionNumber>
<AccessionNumber>KM113068</AccessionNumber>
<AccessionNumber>KM113069</AccessionNumber>
<AccessionNumber>KM113070</AccessionNumber>
<AccessionNumber>KM113071</AccessionNumber>
<AccessionNumber>KM113072</AccessionNumber>
<AccessionNumber>KM113073</AccessionNumber>
<AccessionNumber>KM113074</AccessionNumber>
<AccessionNumber>KM113075</AccessionNumber>
<AccessionNumber>KM113076</AccessionNumber>
<AccessionNumber>KM113077</AccessionNumber>
<AccessionNumber>KM113078</AccessionNumber>
<AccessionNumber>KM113079</AccessionNumber>
<AccessionNumber>KM113080</AccessionNumber>
<AccessionNumber>KM113081</AccessionNumber>
<AccessionNumber>KM113082</AccessionNumber>
<AccessionNumber>KM113083</AccessionNumber>
<AccessionNumber>KM113084</AccessionNumber>
<AccessionNumber>KM113085</AccessionNumber>
<AccessionNumber>KM113086</AccessionNumber>
<AccessionNumber>KM113087</AccessionNumber>
<AccessionNumber>KM113088</AccessionNumber>
<AccessionNumber>KM113089</AccessionNumber>
<AccessionNumber>KM113090</AccessionNumber>
<AccessionNumber>KM113091</AccessionNumber>
<AccessionNumber>KM113092</AccessionNumber>
<AccessionNumber>KM113093</AccessionNumber>
<AccessionNumber>KM113094</AccessionNumber>
<AccessionNumber>KM113095</AccessionNumber>
<AccessionNumber>KM113096</AccessionNumber>
<AccessionNumber>KM113097</AccessionNumber>
<AccessionNumber>KM113098</AccessionNumber>
<AccessionNumber>KM113099</AccessionNumber>
<AccessionNumber>KM113100</AccessionNumber>
<AccessionNumber>KM113101</AccessionNumber>
<AccessionNumber>KM113102</AccessionNumber>
<AccessionNumber>KM113103</AccessionNumber>
<AccessionNumber>KM113104</AccessionNumber>
<AccessionNumber>KM113105</AccessionNumber>
<AccessionNumber>KM113106</AccessionNumber>
<AccessionNumber>KM113107</AccessionNumber>
<AccessionNumber>KM113108</AccessionNumber>
<AccessionNumber>KM113109</AccessionNumber>
<AccessionNumber>KM113110</AccessionNumber>
<AccessionNumber>KM113111</AccessionNumber>
<AccessionNumber>KM113112</AccessionNumber>
<AccessionNumber>KM113113</AccessionNumber>
<AccessionNumber>KM113114</AccessionNumber>
<AccessionNumber>KM113115</AccessionNumber>
<AccessionNumber>KM113116</AccessionNumber>
<AccessionNumber>KM113117</AccessionNumber>
<AccessionNumber>KM113118</AccessionNumber>
<AccessionNumber>KM113119</AccessionNumber>
<AccessionNumber>KM113120</AccessionNumber>
<AccessionNumber>KM113121</AccessionNumber>
<AccessionNumber>KM113122</AccessionNumber>
<AccessionNumber>KM113123</AccessionNumber>
<AccessionNumber>KM113124</AccessionNumber>
<AccessionNumber>KM113125</AccessionNumber>
<AccessionNumber>KM113126</AccessionNumber>
<AccessionNumber>KM113127</AccessionNumber>
<AccessionNumber>KM113128</AccessionNumber>
<AccessionNumber>KM113129</AccessionNumber>
<AccessionNumber>KM113130</AccessionNumber>
<AccessionNumber>KM113131</AccessionNumber>
<AccessionNumber>KM113132</AccessionNumber>
<AccessionNumber>KM113133</AccessionNumber>
<AccessionNumber>KM113134</AccessionNumber>
<AccessionNumber>KM113135</AccessionNumber>
<AccessionNumber>KM113136</AccessionNumber>
<AccessionNumber>KM113137</AccessionNumber>
<AccessionNumber>KM113138</AccessionNumber>
<AccessionNumber>KM113139</AccessionNumber>
<AccessionNumber>KM113140</AccessionNumber>
<AccessionNumber>KM113141</AccessionNumber>
<AccessionNumber>KM113142</AccessionNumber>
<AccessionNumber>KM113143</AccessionNumber>
<AccessionNumber>KM113144</AccessionNumber>
<AccessionNumber>KM113145</AccessionNumber>
<AccessionNumber>KM113146</AccessionNumber>
<AccessionNumber>KM113147</AccessionNumber>
<AccessionNumber>KM113148</AccessionNumber>
<AccessionNumber>KM113149</AccessionNumber>
<AccessionNumber>KM113150</AccessionNumber>
<AccessionNumber>KM113151</AccessionNumber>
<AccessionNumber>KM113152</AccessionNumber>
<AccessionNumber>KM113153</AccessionNumber>
<AccessionNumber>KM113154</AccessionNumber>
<AccessionNumber>KM113155</AccessionNumber>
<AccessionNumber>KM113156</AccessionNumber>
<AccessionNumber>KM113157</AccessionNumber>
<AccessionNumber>KM113158</AccessionNumber>
<AccessionNumber>KM113159</AccessionNumber>
<AccessionNumber>KM113160</AccessionNumber>
<AccessionNumber>KM113161</AccessionNumber>
<AccessionNumber>KM113162</AccessionNumber>
<AccessionNumber>KM113163</AccessionNumber>
<AccessionNumber>KM113164</AccessionNumber>
<AccessionNumber>KM113165</AccessionNumber>
<AccessionNumber>KM113166</AccessionNumber>
<AccessionNumber>KM113167</AccessionNumber>
<AccessionNumber>KM113168</AccessionNumber>
<AccessionNumber>KM113169</AccessionNumber>
<AccessionNumber>KM113170</AccessionNumber>
<AccessionNumber>KM113171</AccessionNumber>
<AccessionNumber>KM113172</AccessionNumber>
<AccessionNumber>KM113173</AccessionNumber>
<AccessionNumber>KM113174</AccessionNumber>
<AccessionNumber>KM113175</AccessionNumber>
<AccessionNumber>KM113176</AccessionNumber>
<AccessionNumber>KM113177</AccessionNumber>
<AccessionNumber>KM113178</AccessionNumber>
<AccessionNumber>KM113179</AccessionNumber>
<AccessionNumber>KM113180</AccessionNumber>
<AccessionNumber>KM113181</AccessionNumber>
<AccessionNumber>KM113182</AccessionNumber>
<AccessionNumber>KM113183</AccessionNumber>
<AccessionNumber>KM113184</AccessionNumber>
<AccessionNumber>KM113185</AccessionNumber>
<AccessionNumber>KM113186</AccessionNumber>
<AccessionNumber>KM113187</AccessionNumber>
<AccessionNumber>KM113188</AccessionNumber>
<AccessionNumber>KM113189</AccessionNumber>
<AccessionNumber>KM113190</AccessionNumber>
<AccessionNumber>KM113191</AccessionNumber>
<AccessionNumber>KM113192</AccessionNumber>
<AccessionNumber>KM113193</AccessionNumber>
<AccessionNumber>KM113194</AccessionNumber>
<AccessionNumber>KM113195</AccessionNumber>
<AccessionNumber>KM113196</AccessionNumber>
<AccessionNumber>KM113197</AccessionNumber>
<AccessionNumber>KM113198</AccessionNumber>
<AccessionNumber>KM113199</AccessionNumber>
<AccessionNumber>KM113200</AccessionNumber>
<AccessionNumber>KM113201</AccessionNumber>
<AccessionNumber>KM113202</AccessionNumber>
<AccessionNumber>KM113203</AccessionNumber>
<AccessionNumber>KM113204</AccessionNumber>
<AccessionNumber>KM113205</AccessionNumber>
<AccessionNumber>KM113206</AccessionNumber>
<AccessionNumber>KM113207</AccessionNumber>
<AccessionNumber>KM113208</AccessionNumber>
<AccessionNumber>KM113209</AccessionNumber>
<AccessionNumber>KM113210</AccessionNumber>
<AccessionNumber>KM113211</AccessionNumber>
<AccessionNumber>KM113212</AccessionNumber>
<AccessionNumber>KM113213</AccessionNumber>
<AccessionNumber>KM113214</AccessionNumber>
<AccessionNumber>KM113215</AccessionNumber>
<AccessionNumber>KM113216</AccessionNumber>
<AccessionNumber>KM113217</AccessionNumber>
<AccessionNumber>KM113218</AccessionNumber>
<AccessionNumber>KM113219</AccessionNumber>
<AccessionNumber>KM113220</AccessionNumber>
<AccessionNumber>KM113221</AccessionNumber>
<AccessionNumber>KM113222</AccessionNumber>
<AccessionNumber>KM113223</AccessionNumber>
<AccessionNumber>KM113224</AccessionNumber>
<AccessionNumber>KM113225</AccessionNumber>
<AccessionNumber>KM113226</AccessionNumber>
<AccessionNumber>KM113227</AccessionNumber>
<AccessionNumber>KM113228</AccessionNumber>
<AccessionNumber>KM113229</AccessionNumber>
<AccessionNumber>KM113230</AccessionNumber>
<AccessionNumber>KM113231</AccessionNumber>
<AccessionNumber>KM113232</AccessionNumber>
<AccessionNumber>KM113233</AccessionNumber>
<AccessionNumber>KM113234</AccessionNumber>
<AccessionNumber>KM113235</AccessionNumber>
<AccessionNumber>KM113236</AccessionNumber>
<AccessionNumber>KM113237</AccessionNumber>
<AccessionNumber>KM113238</AccessionNumber>
<AccessionNumber>KM113239</AccessionNumber>
<AccessionNumber>KM113240</AccessionNumber>
<AccessionNumber>KM113241</AccessionNumber>
<AccessionNumber>KM113242</AccessionNumber>
<AccessionNumber>KM113243</AccessionNumber>
<AccessionNumber>KM113244</AccessionNumber>
<AccessionNumber>KM113245</AccessionNumber>
<AccessionNumber>KM113246</AccessionNumber>
<AccessionNumber>KM113247</AccessionNumber>
<AccessionNumber>KM113248</AccessionNumber>
<AccessionNumber>KM113249</AccessionNumber>
<AccessionNumber>KM113250</AccessionNumber>
<AccessionNumber>KM113251</AccessionNumber>
<AccessionNumber>KM113252</AccessionNumber>
<AccessionNumber>KM113253</AccessionNumber>
<AccessionNumber>KM113254</AccessionNumber>
<AccessionNumber>KM113255</AccessionNumber>
<AccessionNumber>KM113256</AccessionNumber>
<AccessionNumber>KM113257</AccessionNumber>
<AccessionNumber>KM113258</AccessionNumber>
<AccessionNumber>KM113259</AccessionNumber>
<AccessionNumber>KM113260</AccessionNumber>
<AccessionNumber>KM113261</AccessionNumber>
<AccessionNumber>KM113262</AccessionNumber>
<AccessionNumber>KM113263</AccessionNumber>
<AccessionNumber>KM113264</AccessionNumber>
<AccessionNumber>KM113265</AccessionNumber>
<AccessionNumber>KM113266</AccessionNumber>
<AccessionNumber>KM113267</AccessionNumber>
<AccessionNumber>KM113268</AccessionNumber>
<AccessionNumber>KM113269</AccessionNumber>
<AccessionNumber>KM113270</AccessionNumber>
<AccessionNumber>KM113271</AccessionNumber>
<AccessionNumber>KM113272</AccessionNumber>
<AccessionNumber>KM113273</AccessionNumber>
<AccessionNumber>KM113274</AccessionNumber>
<AccessionNumber>KM113275</AccessionNumber>
<AccessionNumber>KM113276</AccessionNumber>
<AccessionNumber>KM113277</AccessionNumber>
<AccessionNumber>KM113278</AccessionNumber>
<AccessionNumber>KM113279</AccessionNumber>
<AccessionNumber>KM113280</AccessionNumber>
<AccessionNumber>KM113281</AccessionNumber>
<AccessionNumber>KM113282</AccessionNumber>
<AccessionNumber>KM113283</AccessionNumber>
<AccessionNumber>KM113284</AccessionNumber>
<AccessionNumber>KM113285</AccessionNumber>
<AccessionNumber>KM113286</AccessionNumber>
<AccessionNumber>KM113287</AccessionNumber>
<AccessionNumber>KM113288</AccessionNumber>
<AccessionNumber>KM113289</AccessionNumber>
<AccessionNumber>KM113290</AccessionNumber>
<AccessionNumber>KM113291</AccessionNumber>
<AccessionNumber>KM113292</AccessionNumber>
<AccessionNumber>KM113293</AccessionNumber>
<AccessionNumber>KM113294</AccessionNumber>
<AccessionNumber>KM113295</AccessionNumber>
<AccessionNumber>KM113296</AccessionNumber>
<AccessionNumber>KM113297</AccessionNumber>
<AccessionNumber>KM113298</AccessionNumber>
<AccessionNumber>KM113299</AccessionNumber>
<AccessionNumber>KM113300</AccessionNumber>
<AccessionNumber>KM113301</AccessionNumber>
<AccessionNumber>KM113302</AccessionNumber>
<AccessionNumber>KM113303</AccessionNumber>
<AccessionNumber>KM113304</AccessionNumber>
<AccessionNumber>KM113305</AccessionNumber>
<AccessionNumber>KM113306</AccessionNumber>
<AccessionNumber>KM113307</AccessionNumber>
<AccessionNumber>KM113308</AccessionNumber>
<AccessionNumber>KM113309</AccessionNumber>
<AccessionNumber>KM113310</AccessionNumber>
<AccessionNumber>KM113311</AccessionNumber>
<AccessionNumber>KM113312</AccessionNumber>
<AccessionNumber>KM113313</AccessionNumber>
<AccessionNumber>KM113314</AccessionNumber>
<AccessionNumber>KM113315</AccessionNumber>
<AccessionNumber>KM113316</AccessionNumber>
<AccessionNumber>KM113317</AccessionNumber>
<AccessionNumber>KM113318</AccessionNumber>
<AccessionNumber>KM113319</AccessionNumber>
<AccessionNumber>KM113320</AccessionNumber>
<AccessionNumber>KM113321</AccessionNumber>
</AccessionNumberList>
</DataBank>
</DataBankList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2014</Year>
<Month>11</Month>
<Day>20</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>PLoS Pathog</MedlineTA>
<NlmUniqueID>101238921</NlmUniqueID>
<ISSNLinking>1553-7366</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>PLoS Pathog. 2020 Jan 8;16(1):e1008284</RefSource>
<PMID Version="1">31914139</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001483" MajorTopicYN="N">Base Sequence</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002645" MajorTopicYN="N">Chickens</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002681" MajorTopicYN="N" Type="Geographic">China</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004285" MajorTopicYN="N">Dogs</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005289" MajorTopicYN="N">Ferrets</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014644" MajorTopicYN="Y">Genetic Variation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053127" MajorTopicYN="Y">Influenza A Virus, H9N2 Subtype</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005585" MajorTopicYN="Y">Influenza in Birds</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="Y">Influenza, Human</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D061985" MajorTopicYN="N">Madin Darby Canine Kidney Cells</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008969" MajorTopicYN="N">Molecular Sequence Data</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011201" MajorTopicYN="N">Poultry Diseases</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year>
<Month>05</Month>
<Day>09</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2014</Year>
<Month>10</Month>
<Day>08</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2014</Year>
<Month>11</Month>
<Day>21</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2014</Year>
<Month>11</Month>
<Day>21</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2015</Year>
<Month>10</Month>
<Day>16</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">25411973</ArticleId>
<ArticleId IdType="doi">10.1371/journal.ppat.1004508</ArticleId>
<ArticleId IdType="pii">PPATHOGENS-D-14-01090</ArticleId>
<ArticleId IdType="pmc">PMC4239090</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Virology. 2001 Mar 15;281(2):156-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11277689</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2014 Mar;88(6):3568-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24403592</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2001 Sep 7;293(5536):1840-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11546875</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Antimicrob Agents Chemother. 2001 Oct;45(10):2723-32</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11557461</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2001 Oct;75(20):9679-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11559800</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1356-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14745020</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2004 Feb 21;363(9409):587-93</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14987882</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10452-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15235128</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Microbes Infect. 2004 Aug;6(10):919-25</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15310468</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Avian Dis. 1970 May;14(2):240-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">5427232</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1983 Jun;127(2):361-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6868370</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1988 Mar;163(1):247-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3348002</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 1989 Jun;159(6):1050-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2723453</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Res. 1996 Oct;44(2):79-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8879138</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1998 Sep;72(9):7626-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9696865</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 1999 Sep 11;354(9182):916-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10489954</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2005 Sep 15;340(1):70-83</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16026813</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Sep;79(18):12058-64</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16140781</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2005 Nov;43(11):5760-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16272514</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2007 Feb 2;315(5812):655-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17272724</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Aug;81(16):8515-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17553873</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2008 Feb;82(3):1146-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18032512</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2008;3(8):e2923</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18698430</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Microbiol. 2008 Sep 18;131(1-2):82-92</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18403137</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2008 Nov;82(21):10854-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18715930</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2009 Jan;5(1):e1000252</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19119420</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2009 Feb 5;384(1):28-32</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19117585</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2009 May 5;106(18):7565-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19380727</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2009 Jun 11;360(24):2583-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19516044</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2009 Sep;83(17):8428-38</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19553328</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2009 Dec;5(12):e1000709</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20041223</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2010 Sep;84(17):8389-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20538856</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4164-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21368167</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2011 Jun;92(Pt 6):1435-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21367983</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Virol. 2011 Jun;51(2):132-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21530384</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2011 May;7(5):e1002068</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21637809</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12084-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21730147</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2011 Dec;85(24):13271-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21994462</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2012;7(5):e36374</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22623954</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2012 Jun 21;486(7403):420-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22722205</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2012 Jun 22;336(6088):1534-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22723413</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2012 Sep;86(18):9666-74</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22740390</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2012;7(8):e43948</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22928049</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Med Virol. 2013 Apr;85(4):670-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23400898</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Public Health. 2013 Apr;6(2):69-79</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23537819</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2013 May 16;368(20):1888-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23577628</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2013 Jun 1;381(9881):1916-25</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23623390</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2013 Jun 21;340(6139):1459-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23641061</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2013 Jul 26;341(6144):410-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23868922</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2013 Sep;87(17):9452-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23804642</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2013 Sep 26;501(7468):551-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23842494</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2013 Nov;57(9):1367-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23881153</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Public Health. 2013 Dec;6(6):438-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23999337</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2014 Apr;95(Pt 4):779-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24394699</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2014 Apr;88(8):3953-64</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24501418</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 2014 Apr 10;157(2):329-39</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24725402</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Virol. 2014 Oct;159(10):2575-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24838853</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Zoonoses Public Health. 2015 Mar;62(2):131-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24803167</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2014 Feb 22;383(9918):714-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24507376</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2001 May;75(10):4896-901</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11312361</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/PubMed/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000737 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000737 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    PandemieGrippaleV1
   |flux=    PubMed
   |étape=   Curation
   |type=    RBID
   |clé=     pubmed:25411973
   |texte=   Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i   -Sk "pubmed:25411973" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a PandemieGrippaleV1

This area was generated with Dilib version V0.6.34.
Data generation: Wed Jun 10 11:04:28 2020. Site generation: Sun Mar 28 09:10:28 2021

	Serveur d'exploration sur les pandémies grippales
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur les pandémies grippales

Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses.

Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki