Characteristics and outcome of ill critical patients with influenza A infection.
Identifieur interne : 000274 ( PubMed/Curation ); précédent : 000273; suivant : 000275Characteristics and outcome of ill critical patients with influenza A infection.
Auteurs : Rania Bouneb [Tunisie] ; Manel Mellouli [Tunisie] ; Houda Bensoltane [Tunisie] ; Jamila Baroudi [Tunisie] ; Imed Chouchene [Tunisie] ; Mohamed Boussarsar [Tunisie]Source :
- The Pan African medical journal [ 1937-8688 ] ; 2018.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Analyse multivariée, Broncho-pneumopathie chronique obstructive, Facteurs de l'âge, Facteurs de risque, Facteurs sexuels, Femelle, Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains, Maladie grave, Modèles logistiques, Mâle, RT-PCR, Saisons, Sous-type H1N1 du virus de la grippe A (isolement et purification), Syndrome de détresse respiratoire de l'adulte (épidémiologie), Tunisie (épidémiologie), Unités de soins intensifs, Études de cohortes, Études rétrospectives.
- MESH :
- isolement et purification : Sous-type H1N1 du virus de la grippe A.
- virologie : Grippe humaine.
- épidémiologie : Grippe humaine, Syndrome de détresse respiratoire de l'adulte, Tunisie.
- Adulte, Adulte d'âge moyen, Analyse multivariée, Broncho-pneumopathie chronique obstructive, Facteurs de l'âge, Facteurs de risque, Facteurs sexuels, Femelle, Humains, Maladie grave, Modèles logistiques, Mâle, RT-PCR, Saisons, Unités de soins intensifs, Études de cohortes, Études rétrospectives.
English descriptors
- KwdEn :
- Adult, Age Factors, Cohort Studies, Critical Illness, Female, Humans, Influenza A Virus, H1N1 Subtype (isolation & purification), Influenza, Human (epidemiology), Influenza, Human (virology), Intensive Care Units, Logistic Models, Male, Middle Aged, Multivariate Analysis, Pulmonary Disease, Chronic Obstructive, Respiratory Distress Syndrome, Adult (epidemiology), Retrospective Studies, Reverse Transcriptase Polymerase Chain Reaction, Risk Factors, Seasons, Sex Factors, Tunisia (epidemiology).
- MESH :
- epidemiology : Influenza, Human, Respiratory Distress Syndrome, Adult, Tunisia.
- isolation & purification : Influenza A Virus, H1N1 Subtype.
- virology : Influenza, Human.
- Adult, Age Factors, Cohort Studies, Critical Illness, Female, Humans, Intensive Care Units, Logistic Models, Male, Middle Aged, Multivariate Analysis, Pulmonary Disease, Chronic Obstructive, Retrospective Studies, Reverse Transcriptase Polymerase Chain Reaction, Risk Factors, Seasons, Sex Factors.
Abstract
To describe all patients admitted to Tunisian intensive care unit with a diagnosis of influenza A/H1N1 virus infection after the 2009 influenza pandemic and to analyse their characteristics, predictors of complications and outcome.
DOI: 10.11604/pamj.2018.29.174.13098
PubMed: 30050638
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respiratoire de l'adulte</term><term>Tunisie</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>Cohort Studies</term><term>Critical Illness</term><term>Female</term><term>Humans</term><term>Intensive Care Units</term><term>Logistic Models</term><term>Male</term><term>Middle Aged</term><term>Multivariate Analysis</term><term>Pulmonary Disease, Chronic Obstructive</term><term>Retrospective Studies</term><term>Reverse Transcriptase Polymerase Chain Reaction</term><term>Risk Factors</term><term>Seasons</term><term>Sex Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse multivariée</term><term>Broncho-pneumopathie chronique obstructive</term><term>Facteurs de l'âge</term><term>Facteurs de risque</term><term>Facteurs sexuels</term><term>Femelle</term><term>Humains</term><term>Maladie grave</term><term>Modèles logistiques</term><term>Mâle</term><term>RT-PCR</term><term>Saisons</term><term>Unités de soins intensifs</term><term>Études de cohortes</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To describe all patients admitted to Tunisian intensive care unit with a diagnosis of influenza A/H1N1 virus infection after the 2009 influenza pandemic and to analyse their characteristics, predictors of complications and outcome.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30050638</PMID><DateCompleted><Year>2018</Year><Month>08</Month><Day>13</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>14</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1937-8688</ISSN><JournalIssue CitedMedium="Internet"><Volume>29</Volume><PubDate><Year>2018</Year></PubDate></JournalIssue><Title>The Pan African medical journal</Title><ISOAbbreviation>Pan Afr Med J</ISOAbbreviation></Journal><ArticleTitle>Characteristics and outcome of ill critical patients with influenza A infection.</ArticleTitle><Pagination><MedlinePgn>174</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.11604/pamj.2018.29.174.13098</ELocationID><Abstract><AbstractText Label="Introduction" NlmCategory="UNASSIGNED">To describe all patients admitted to Tunisian intensive care unit with a diagnosis of influenza A/H1N1 virus infection after the 2009 influenza pandemic and to analyse their characteristics, predictors of complications and outcome.</AbstractText><AbstractText Label="Methods" NlmCategory="UNASSIGNED">All patients with influenza > 18-years-old hospitalized to the ICU department of Tunisian University hospital of Sousse, between December 1, 2009 and March 31, 2016, with a positive influenza A/H1N1/09 reverse transcriptase polymerase chain reaction (RT-PCR) from a nasopharyngeal specimen were included, were included.</AbstractText><AbstractText Label="Results" NlmCategory="UNASSIGNED">40 cases were admitted to intensive care units. During the reporting period, 22 deaths in intensive care units (55%) were reported, the median age was 53 years (IQR 37-61), 24 (61%) were male, The median scores SAPS II and SOFA were respectively 29 (IQR 23-36) and 6 (IQR 3-10), 27% had chronic obstructive pulmonary disease (COPD), 33.3% diabetic and no patients were vaccinated against influenza A. The cause of admission was in 72.5% of the cases was hypoxemic pneumonae. By using a logistic regression, we found after adjustment to age, that acute respiratory distress syndrome (ARDS) (OR = 27; 95%CI: 3.62-203.78) was the only factor significantly associated with severe outcomes of the cases.</AbstractText><AbstractText Label="Conclusion" NlmCategory="UNASSIGNED">Patients in the first post pandemic season were significantly older and more frequently had underlying medical conditions. Multivariate analysis showed that older male patients with chronic lung disease were at increased risk for a severe clinical outcome.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bouneb</LastName><ForeName>Rania</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Intensive Care Unit, University Hospital of Farhat Hached, Susah, Tunisia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mellouli</LastName><ForeName>Manel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Preventive Medicine, Faculty of Medicine, Susah, Tunisia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bensoltane</LastName><ForeName>Houda</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Emergency, University Hospital of Farhat Hached, Susah, Tunisia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Baroudi</LastName><ForeName>Jamila</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Intensive Care Unit, University Hospital of Farhat Hached, Susah, Tunisia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chouchene</LastName><ForeName>Imed</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Intensive Care Unit, University Hospital of Farhat Hached, Susah, Tunisia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boussarsar</LastName><ForeName>Mohamed</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Intensive Care Unit, University Hospital of Farhat Hached, Susah, Tunisia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2018</Year><Month>03</Month><Day>26</Day></ArticleDate></Article><MedlineJournalInfo><Country>Uganda</Country><MedlineTA>Pan Afr Med J</MedlineTA><NlmUniqueID>101517926</NlmUniqueID></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000367" MajorTopicYN="N">Age Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016638" MajorTopicYN="N">Critical Illness</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D053118" MajorTopicYN="N">Influenza A Virus, H1N1 Subtype</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007362" MajorTopicYN="Y">Intensive Care Units</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016015" MajorTopicYN="N">Logistic Models</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015999" MajorTopicYN="N">Multivariate Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D029424" MajorTopicYN="N">Pulmonary Disease, Chronic Obstructive</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012128" MajorTopicYN="N">Respiratory Distress Syndrome, Adult</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020133" MajorTopicYN="N">Reverse Transcriptase Polymerase Chain Reaction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012621" MajorTopicYN="N">Seasons</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012737" MajorTopicYN="N">Sex Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014416" MajorTopicYN="N">Tunisia</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">H1N1</Keyword><Keyword MajorTopicYN="N">influenza virus</Keyword><Keyword MajorTopicYN="N">intensive care unit</Keyword><Keyword MajorTopicYN="N">prognosis</Keyword><Keyword MajorTopicYN="N">risk factors</Keyword><Keyword MajorTopicYN="N">symptoms</Keyword><Keyword MajorTopicYN="N">treatment</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>06</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>03</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>7</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>7</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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