Public Health-Driven Research and Innovation for Next-Generation Influenza Vaccines, European Union.
Identifieur interne : 000177 ( PubMed/Curation ); précédent : 000176; suivant : 000178Public Health-Driven Research and Innovation for Next-Generation Influenza Vaccines, European Union.
Auteurs : Adoraci N Navarro-Torné ; Finnian Hanrahan ; Barbara Kerstiëns ; Pilar Aguar ; Line MatthiessenSource :
- Emerging infectious diseases [ 1080-6059 ] ; 2019.
Descripteurs français
- KwdFr :
- MESH :
- immunologie : Vaccins antigrippaux, Virus de la grippe A.
- épidémiologie : Grippe humaine.
- Biotechnologie, Grippe humaine, Humains, Recherche, Santé publique, Union européenne.
English descriptors
- KwdEn :
- MESH :
- chemical , immunology : Influenza Vaccines.
- epidemiology : Influenza, Human.
- immunology : Influenza A virus.
- prevention & control : Influenza, Human.
- Biotechnology, European Union, Humans, Public Health, Research, Vaccinology.
Abstract
Influenza virus infections are a major public health threat. Vaccination is available, but unpredictable antigenic changes in circulating strains require annual modification of seasonal influenza vaccines. Vaccine effectiveness has proven limited, particularly in certain groups, such as the elderly. Moreover, preparedness for upcoming pandemics is challenging because we can predict neither the strain that will cause the next pandemic nor the severity of the pandemic. The European Union fosters research and innovation to develop novel vaccines that evoke broadly protective and long-lasting immune responses against both seasonal and pandemic influenza, underpinned by a political commitment to global public health.
DOI: 10.3201/eid2502.180359
PubMed: 30666948
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<front><div type="abstract" xml:lang="en">Influenza virus infections are a major public health threat. Vaccination is available, but unpredictable antigenic changes in circulating strains require annual modification of seasonal influenza vaccines. Vaccine effectiveness has proven limited, particularly in certain groups, such as the elderly. Moreover, preparedness for upcoming pandemics is challenging because we can predict neither the strain that will cause the next pandemic nor the severity of the pandemic. The European Union fosters research and innovation to develop novel vaccines that evoke broadly protective and long-lasting immune responses against both seasonal and pandemic influenza, underpinned by a political commitment to global public health.</div>
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