Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic.
Identifieur interne : 000035 ( PubMed/Curation ); précédent : 000034; suivant : 000036Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic.
Auteurs : Livio Luzi [Italie] ; Maria Grazia Radaelli [Italie]Source :
- Acta diabetologica [ 1432-5233 ] ; 2020.
Descripteurs français
- KwdFr :
- Excrétion virale, Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains, Infections à coronavirus (), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Obésité (immunologie), Obésité (physiopathologie), Obésité (virologie), Obésité (épidémiologie), Pandémies (), Pneumopathie virale (), Pneumopathie virale (virologie), Pneumopathie virale (épidémiologie), Prévalence, Quarantaine.
- MESH :
- immunologie : Obésité.
- physiopathologie : Obésité.
- virologie : Grippe humaine, Infections à coronavirus, Obésité, Pneumopathie virale.
- épidémiologie : Grippe humaine, Infections à coronavirus, Obésité, Pneumopathie virale.
- Excrétion virale, Humains, Infections à coronavirus, Pandémies, Pneumopathie virale, Prévalence, Quarantaine.
English descriptors
- KwdEn :
- Betacoronavirus (isolation & purification), Coronavirus Infections (epidemiology), Coronavirus Infections (prevention & control), Coronavirus Infections (virology), Humans, Influenza, Human (epidemiology), Influenza, Human (virology), Obesity (epidemiology), Obesity (immunology), Obesity (physiopathology), Obesity (virology), Pandemics (prevention & control), Pneumonia, Viral (epidemiology), Pneumonia, Viral (prevention & control), Pneumonia, Viral (virology), Prevalence, Quarantine, Virus Shedding.
- MESH :
- epidemiology : Coronavirus Infections, Influenza, Human, Obesity, Pneumonia, Viral.
- immunology : Obesity.
- isolation & purification : Betacoronavirus.
- physiopathology : Obesity.
- prevention & control : Coronavirus Infections, Pandemics, Pneumonia, Viral.
- virology : Coronavirus Infections, Influenza, Human, Obesity, Pneumonia, Viral.
- Humans, Prevalence, Quarantine, Virus Shedding.
Abstract
Analyze the relationship between obesity and influenza.
DOI: 10.1007/s00592-020-01522-8
PubMed: 32249357
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pubmed:32249357Le document en format XML
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<author><name sortKey="Luzi, Livio" sort="Luzi, Livio" uniqKey="Luzi L" first="Livio" last="Luzi">Livio Luzi</name>
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<author><name sortKey="Radaelli, Maria Grazia" sort="Radaelli, Maria Grazia" uniqKey="Radaelli M" first="Maria Grazia" last="Radaelli">Maria Grazia Radaelli</name>
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<term>Coronavirus Infections (virology)</term>
<term>Humans</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (virology)</term>
<term>Obesity (epidemiology)</term>
<term>Obesity (immunology)</term>
<term>Obesity (physiopathology)</term>
<term>Obesity (virology)</term>
<term>Pandemics (prevention & control)</term>
<term>Pneumonia, Viral (epidemiology)</term>
<term>Pneumonia, Viral (prevention & control)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Excrétion virale</term>
<term>Grippe humaine (virologie)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Humains</term>
<term>Infections à coronavirus ()</term>
<term>Infections à coronavirus (virologie)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Obésité (immunologie)</term>
<term>Obésité (physiopathologie)</term>
<term>Obésité (virologie)</term>
<term>Obésité (épidémiologie)</term>
<term>Pandémies ()</term>
<term>Pneumopathie virale ()</term>
<term>Pneumopathie virale (virologie)</term>
<term>Pneumopathie virale (épidémiologie)</term>
<term>Prévalence</term>
<term>Quarantaine</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Influenza, Human</term>
<term>Obesity</term>
<term>Pneumonia, Viral</term>
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<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Obésité</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Obesity</term>
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<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Betacoronavirus</term>
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<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Obésité</term>
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<term>Pandemics</term>
<term>Pneumonia, Viral</term>
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<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe humaine</term>
<term>Infections à coronavirus</term>
<term>Obésité</term>
<term>Pneumopathie virale</term>
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<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Influenza, Human</term>
<term>Obesity</term>
<term>Pneumonia, Viral</term>
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<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Grippe humaine</term>
<term>Infections à coronavirus</term>
<term>Obésité</term>
<term>Pneumopathie virale</term>
</keywords>
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<term>Prevalence</term>
<term>Quarantine</term>
<term>Virus Shedding</term>
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<term>Humains</term>
<term>Infections à coronavirus</term>
<term>Pandémies</term>
<term>Pneumopathie virale</term>
<term>Prévalence</term>
<term>Quarantaine</term>
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<front><div type="abstract" xml:lang="en">Analyze the relationship between obesity and influenza.</div>
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<pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">32249357</PMID>
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<Month>05</Month>
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<Issue>6</Issue>
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<Title>Acta diabetologica</Title>
<ISOAbbreviation>Acta Diabetol</ISOAbbreviation>
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<ArticleTitle>Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic.</ArticleTitle>
<Pagination><MedlinePgn>759-764</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1007/s00592-020-01522-8</ELocationID>
<Abstract><AbstractText Label="AIMS" NlmCategory="OBJECTIVE">Analyze the relationship between obesity and influenza.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Basal hormone milieu, defective response of both innate and adaptive immune system and sedentariness are major determinants in the severity of influenza viral infection in obese patients. Being overweight not only increases the risk of infection and of complications for the single obese person, but a large prevalence of obese individuals within the population might increase the chance of appearance of more virulent viral strain, prolongs the virus shedding throughout the total population and eventually might increase overall mortality rate of an influenza pandemic.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Waiting for the development of a vaccination against COVID-19, isolation of positive cases and social distancing are the primary interventions. Nonetheless, evidence from previous influenza pandemics suggests the following interventions aimed at improving immune response: (1) lose weight with a mild caloric restriction; (2) include AMPK activators and PPAR gamma activators in the drug treatment for obesity associated with diabetes; and (3) practice mild-to-moderate physical exercise.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Due to prolonged viral shedding, quarantine in obese subjects should likely be longer than normal weight individuals.</AbstractText>
</Abstract>
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<ForeName>Livio</ForeName>
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<AffiliationInfo><Affiliation>Department of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, Milan, Italy. livio.luzi@multimedica.it.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Biomedical Sciences and Health, Università degli Studi di Milano, Milan, Italy. livio.luzi@multimedica.it.</Affiliation>
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<Author ValidYN="Y"><LastName>Radaelli</LastName>
<ForeName>Maria Grazia</ForeName>
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<AffiliationInfo><Affiliation>Department of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, Milan, Italy.</Affiliation>
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<MeshHeading><DescriptorName UI="D009765" MajorTopicYN="N">Obesity</DescriptorName>
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