Influenza: lessons from past pandemics, warnings from current incidents.
Identifieur interne : 001E51 ( PubMed/Corpus ); précédent : 001E50; suivant : 001E52Influenza: lessons from past pandemics, warnings from current incidents.
Auteurs : Taisuke Horimoto ; Yoshihiro KawaokaSource :
- Nature reviews. Microbiology [ 1740-1526 ] ; 2005.
English descriptors
- KwdEn :
- Animals, Antiviral Agents (therapeutic use), Biomarkers (metabolism), Disease Outbreaks (prevention & control), Humans, Influenza A virus (pathogenicity), Influenza A virus (physiology), Influenza Vaccines (therapeutic use), Influenza in Birds (epidemiology), Influenza in Birds (prevention & control), Influenza in Birds (virology), Influenza, Human (epidemiology), Influenza, Human (prevention & control), Influenza, Human (virology), Poultry, Virulence.
- MESH :
- chemical , metabolism : Biomarkers.
- chemical , therapeutic use : Antiviral Agents, Influenza Vaccines.
- epidemiology : Influenza in Birds, Influenza, Human.
- pathogenicity : Influenza A virus.
- physiology : Influenza A virus.
- prevention & control : Disease Outbreaks, Influenza in Birds, Influenza, Human.
- virology : Influenza in Birds, Influenza, Human.
- Animals, Humans, Poultry, Virulence.
Abstract
Recent outbreaks of highly pathogenic avian influenza A virus infections (H5 and H7 subtypes) in poultry and in humans (through direct contact with infected birds) have had important economic repercussions and have raised concerns that a new influenza pandemic will occur in the near future. The eradication of pathogenic avian influenza viruses seems to be the most effective way to prevent influenza pandemics, although this strategy has not proven successful so far. Here, we review the molecular factors that contribute to the emergence of pandemic strains.
DOI: 10.1038/nrmicro1208
PubMed: 16064053
Links to Exploration step
pubmed:16064053Le document en format XML
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Microbiology</title><idno type="ISSN">1740-1526</idno><imprint><date when="2005" type="published">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antiviral Agents (therapeutic use)</term><term>Biomarkers (metabolism)</term><term>Disease Outbreaks (prevention & control)</term><term>Humans</term><term>Influenza A virus (pathogenicity)</term><term>Influenza A virus (physiology)</term><term>Influenza Vaccines (therapeutic use)</term><term>Influenza in Birds (epidemiology)</term><term>Influenza in Birds (prevention & control)</term><term>Influenza in Birds (virology)</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (prevention & control)</term><term>Influenza, Human (virology)</term><term>Poultry</term><term>Virulence</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Biomarkers</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term><term>Influenza Vaccines</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza in Birds</term><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Disease Outbreaks</term><term>Influenza in Birds</term><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza in Birds</term><term>Influenza, Human</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Humans</term><term>Poultry</term><term>Virulence</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Recent outbreaks of highly pathogenic avian influenza A virus infections (H5 and H7 subtypes) in poultry and in humans (through direct contact with infected birds) have had important economic repercussions and have raised concerns that a new influenza pandemic will occur in the near future. The eradication of pathogenic avian influenza viruses seems to be the most effective way to prevent influenza pandemics, although this strategy has not proven successful so far. Here, we review the molecular factors that contribute to the emergence of pandemic strains.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">16064053</PMID><DateCompleted><Year>2005</Year><Month>08</Month><Day>31</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1740-1526</ISSN><JournalIssue CitedMedium="Print"><Volume>3</Volume><Issue>8</Issue><PubDate><Year>2005</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Nature reviews. Microbiology</Title><ISOAbbreviation>Nat. Rev. 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