Exhaled air and aerosolized droplet dispersion during application of a jet nebulizer.
Identifieur interne : 001799 ( PubMed/Corpus ); précédent : 001798; suivant : 001800Exhaled air and aerosolized droplet dispersion during application of a jet nebulizer.
Auteurs : David S. Hui ; Benny K. Chow ; Leo C Y. Chu ; Susanna S. Ng ; Stephen D. Hall ; Tony Gin ; Matthew T V. ChanSource :
- Chest [ 1931-3543 ] ; 2009.
English descriptors
- KwdEn :
- Aerosols, Air Movements, Exhalation, Hospital Units, Humans, Infectious Disease Transmission, Patient-to-Professional, Influenza, Human (transmission), Lung Compliance, Lung Injury (physiopathology), Lung Injury (therapy), Manikins, Masks, Nebulizers and Vaporizers, Oxygen Consumption, Respiratory System, Ventilation.
- MESH :
- chemical : Aerosols.
- physiopathology : Lung Injury.
- therapy : Lung Injury.
- transmission : Influenza, Human.
- Air Movements, Exhalation, Hospital Units, Humans, Infectious Disease Transmission, Patient-to-Professional, Lung Compliance, Manikins, Masks, Nebulizers and Vaporizers, Oxygen Consumption, Respiratory System, Ventilation.
Abstract
As part of our influenza pandemic preparedness, we studied the dispersion distances of exhaled air and aerosolized droplets during application of a jet nebulizer to a human patient simulator (HPS) programmed at normal lung condition and different severities of lung injury.
DOI: 10.1378/chest.08-1998
PubMed: 19265085
Links to Exploration step
pubmed:19265085Le document en format XML
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<term>Infectious Disease Transmission, Patient-to-Professional</term>
<term>Influenza, Human (transmission)</term>
<term>Lung Compliance</term>
<term>Lung Injury (physiopathology)</term>
<term>Lung Injury (therapy)</term>
<term>Manikins</term>
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<term>Nebulizers and Vaporizers</term>
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<front><div type="abstract" xml:lang="en">As part of our influenza pandemic preparedness, we studied the dispersion distances of exhaled air and aerosolized droplets during application of a jet nebulizer to a human patient simulator (HPS) programmed at normal lung condition and different severities of lung injury.</div>
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<DateCompleted><Year>2009</Year>
<Month>04</Month>
<Day>09</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>03</Month>
<Day>26</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1931-3543</ISSN>
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<Issue>3</Issue>
<PubDate><Year>2009</Year>
<Month>Mar</Month>
</PubDate>
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<Title>Chest</Title>
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<ArticleTitle>Exhaled air and aerosolized droplet dispersion during application of a jet nebulizer.</ArticleTitle>
<Pagination><MedlinePgn>648-654</MedlinePgn>
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<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">As part of our influenza pandemic preparedness, we studied the dispersion distances of exhaled air and aerosolized droplets during application of a jet nebulizer to a human patient simulator (HPS) programmed at normal lung condition and different severities of lung injury.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The experiments were conducted in a hospital isolation room with a pressure of - 5 Pa. Airflow was marked with intrapulmonary smoke. The jet nebulizer was driven by air at a constant flow rate of 6 L/min, with the mask reservoir filled with sterile water and attached to the HPS via a nebulizer mask. The exhaled leakage jet plume was revealed by a laser light sheet and images captured by high-definition video. Smoke concentration in the plume was estimated from the light scattered by smoke and droplet particles.</AbstractText>
<AbstractText Label="FINDINGS" NlmCategory="RESULTS">The maximum dispersion distance of smoke particles through the nebulizer side vent was 0.45 m lateral to the HPS at normal lung condition (oxygen consumption, 200 mL/min; lung compliance, 70 mL/cm H(2)O), but it increased to 0.54 m in mild lung injury (oxygen consumption, 300 mL/min; lung compliance, 35 mL/cm H(2)O), and beyond 0.8 m in severe lung injury (oxygen consumption, 500 mL/min; lung compliance, 10 mL/cm H(2)O). More extensive leakage through the side vents of the nebulizer mask was noted with more severe lung injury.</AbstractText>
<AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">Health-care workers should take extra protective precaution within at least 0.8 m from patients with febrile respiratory illness of unknown etiology receiving treatment via a jet nebulizer even in an isolation room with negative pressure.</AbstractText>
</Abstract>
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<AffiliationInfo><Affiliation>Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The University of New South Wales, Australia. Electronic address: dschui@cuhk.edu.hk.</Affiliation>
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