Using Clinical Research Networks to Assess Severity of an Emerging Influenza Pandemic.
Identifieur interne : 000301 ( PubMed/Corpus ); précédent : 000300; suivant : 000302Using Clinical Research Networks to Assess Severity of an Emerging Influenza Pandemic.
Auteurs : Lone Simonsen ; Elizabeth Higgs ; Robert J. Taylor ; Deborah Wentworth ; Al Cozzi-Lepri ; Sarah Pett ; Dominic E. Dwyer ; Richard Davey ; Ruth Lynfield ; Marcelo Losso ; Kathleen Morales ; Marshall J. Glesby ; Jozef Weckx ; Dianne Carey ; Cliff Lane ; Jens LundgrenSource :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2018.
English descriptors
- KwdEn :
- MESH :
- mortality : Influenza, Human.
- statistics & numerical data : Hospitalization.
- Adolescent, Adult, Aged, Aged, 80 and over, Health Behavior, Humans, Middle Aged, Pandemics, Retrospective Studies, Seasons, Severity of Illness Index, Young Adult.
Abstract
Early clinical severity assessments during the 2009 influenza A H1N1 pandemic (pH1N1) overestimated clinical severity due to selection bias and other factors. We retrospectively investigated how to use data from the International Network for Strategic Initiatives in Global HIV Trials, a global clinical influenza research network, to make more accurate case fatality ratio (CFR) estimates early in a future pandemic, an essential part of pandemic response.
DOI: 10.1093/cid/ciy088
PubMed: 29746631
Links to Exploration step
pubmed:29746631Le document en format XML
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Taylor</name><affiliation><nlm:affiliation>Sage Analytica, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Wentworth, Deborah" sort="Wentworth, Deborah" uniqKey="Wentworth D" first="Deborah" last="Wentworth">Deborah Wentworth</name><affiliation><nlm:affiliation>Division of Biostatistics, University of Minnesota, Minneapolis.</nlm:affiliation></affiliation></author><author><name sortKey="Cozzi Lepri, Al" sort="Cozzi Lepri, Al" uniqKey="Cozzi Lepri A" first="Al" last="Cozzi-Lepri">Al Cozzi-Lepri</name><affiliation><nlm:affiliation>University College, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Pett, Sarah" sort="Pett, Sarah" uniqKey="Pett S" first="Sarah" last="Pett">Sarah Pett</name><affiliation><nlm:affiliation>Medical Research Council Clinical Trials Unit and Clinical Research Group, University College, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Dwyer, Dominic E" sort="Dwyer, Dominic E" uniqKey="Dwyer D" first="Dominic E" last="Dwyer">Dominic E. Dwyer</name><affiliation><nlm:affiliation>Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, Westmead Hospital and University of Sydney, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Davey, Richard" sort="Davey, Richard" uniqKey="Davey R" first="Richard" last="Davey">Richard Davey</name><affiliation><nlm:affiliation>National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Lynfield, Ruth" sort="Lynfield, Ruth" uniqKey="Lynfield R" first="Ruth" last="Lynfield">Ruth Lynfield</name><affiliation><nlm:affiliation>Minnesota Department of Health, St. Paul.</nlm:affiliation></affiliation></author><author><name sortKey="Losso, Marcelo" sort="Losso, Marcelo" uniqKey="Losso M" first="Marcelo" last="Losso">Marcelo Losso</name><affiliation><nlm:affiliation>Hospital J.M. Ramos Mejía, Buenos Aires, Argentina.</nlm:affiliation></affiliation></author><author><name sortKey="Morales, Kathleen" sort="Morales, Kathleen" uniqKey="Morales K" first="Kathleen" last="Morales">Kathleen Morales</name><affiliation><nlm:affiliation>Sage Analytica, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Glesby, Marshall J" sort="Glesby, Marshall J" uniqKey="Glesby M" first="Marshall J" last="Glesby">Marshall J. Glesby</name><affiliation><nlm:affiliation>Weill Cornell Medical College, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Weckx, Jozef" sort="Weckx, Jozef" uniqKey="Weckx J" first="Jozef" last="Weckx">Jozef Weckx</name><affiliation><nlm:affiliation>Testumed Vereniging zonder winstoogmerk, Tessenderlo, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Carey, Dianne" sort="Carey, Dianne" uniqKey="Carey D" first="Dianne" last="Carey">Dianne Carey</name><affiliation><nlm:affiliation>The Kirby Institute, University of New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Lane, Cliff" sort="Lane, Cliff" uniqKey="Lane C" first="Cliff" last="Lane">Cliff Lane</name><affiliation><nlm:affiliation>National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Lundgren, Jens" sort="Lundgren, Jens" uniqKey="Lundgren J" first="Jens" last="Lundgren">Jens Lundgren</name><affiliation><nlm:affiliation>Rigshospitalet and Faculty of Health Sciences, University of Copenhagen, Denmark.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2018">2018</date><idno type="RBID">pubmed:29746631</idno><idno type="pmid">29746631</idno><idno type="doi">10.1093/cid/ciy088</idno><idno type="wicri:Area/PubMed/Corpus">000301</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000301</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Using Clinical Research Networks to Assess Severity of an Emerging Influenza Pandemic.</title><author><name sortKey="Simonsen, Lone" sort="Simonsen, Lone" uniqKey="Simonsen L" first="Lone" last="Simonsen">Lone Simonsen</name><affiliation><nlm:affiliation>Rigshospitalet and Faculty of Health Sciences, University of Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Higgs, Elizabeth" sort="Higgs, Elizabeth" uniqKey="Higgs E" first="Elizabeth" last="Higgs">Elizabeth Higgs</name><affiliation><nlm:affiliation>National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Taylor, Robert J" sort="Taylor, Robert J" uniqKey="Taylor R" first="Robert J" last="Taylor">Robert J. Taylor</name><affiliation><nlm:affiliation>Sage Analytica, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Wentworth, Deborah" sort="Wentworth, Deborah" uniqKey="Wentworth D" first="Deborah" last="Wentworth">Deborah Wentworth</name><affiliation><nlm:affiliation>Division of Biostatistics, University of Minnesota, Minneapolis.</nlm:affiliation></affiliation></author><author><name sortKey="Cozzi Lepri, Al" sort="Cozzi Lepri, Al" uniqKey="Cozzi Lepri A" first="Al" last="Cozzi-Lepri">Al Cozzi-Lepri</name><affiliation><nlm:affiliation>University College, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Pett, Sarah" sort="Pett, Sarah" uniqKey="Pett S" first="Sarah" last="Pett">Sarah Pett</name><affiliation><nlm:affiliation>Medical Research Council Clinical Trials Unit and Clinical Research Group, University College, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Dwyer, Dominic E" sort="Dwyer, Dominic E" uniqKey="Dwyer D" first="Dominic E" last="Dwyer">Dominic E. Dwyer</name><affiliation><nlm:affiliation>Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, Westmead Hospital and University of Sydney, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Davey, Richard" sort="Davey, Richard" uniqKey="Davey R" first="Richard" last="Davey">Richard Davey</name><affiliation><nlm:affiliation>National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Lynfield, Ruth" sort="Lynfield, Ruth" uniqKey="Lynfield R" first="Ruth" last="Lynfield">Ruth Lynfield</name><affiliation><nlm:affiliation>Minnesota Department of Health, St. Paul.</nlm:affiliation></affiliation></author><author><name sortKey="Losso, Marcelo" sort="Losso, Marcelo" uniqKey="Losso M" first="Marcelo" last="Losso">Marcelo Losso</name><affiliation><nlm:affiliation>Hospital J.M. Ramos Mejía, Buenos Aires, Argentina.</nlm:affiliation></affiliation></author><author><name sortKey="Morales, Kathleen" sort="Morales, Kathleen" uniqKey="Morales K" first="Kathleen" last="Morales">Kathleen Morales</name><affiliation><nlm:affiliation>Sage Analytica, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Glesby, Marshall J" sort="Glesby, Marshall J" uniqKey="Glesby M" first="Marshall J" last="Glesby">Marshall J. Glesby</name><affiliation><nlm:affiliation>Weill Cornell Medical College, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Weckx, Jozef" sort="Weckx, Jozef" uniqKey="Weckx J" first="Jozef" last="Weckx">Jozef Weckx</name><affiliation><nlm:affiliation>Testumed Vereniging zonder winstoogmerk, Tessenderlo, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Carey, Dianne" sort="Carey, Dianne" uniqKey="Carey D" first="Dianne" last="Carey">Dianne Carey</name><affiliation><nlm:affiliation>The Kirby Institute, University of New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Lane, Cliff" sort="Lane, Cliff" uniqKey="Lane C" first="Cliff" last="Lane">Cliff Lane</name><affiliation><nlm:affiliation>National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Lundgren, Jens" sort="Lundgren, Jens" uniqKey="Lundgren J" first="Jens" last="Lundgren">Jens Lundgren</name><affiliation><nlm:affiliation>Rigshospitalet and Faculty of Health Sciences, University of Copenhagen, Denmark.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</title><idno type="eISSN">1537-6591</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Health Behavior</term><term>Hospitalization (statistics & numerical data)</term><term>Humans</term><term>Influenza, Human (mortality)</term><term>Middle Aged</term><term>Pandemics</term><term>Retrospective Studies</term><term>Seasons</term><term>Severity of Illness Index</term><term>Young Adult</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Health Behavior</term><term>Humans</term><term>Middle Aged</term><term>Pandemics</term><term>Retrospective Studies</term><term>Seasons</term><term>Severity of Illness Index</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Early clinical severity assessments during the 2009 influenza A H1N1 pandemic (pH1N1) overestimated clinical severity due to selection bias and other factors. We retrospectively investigated how to use data from the International Network for Strategic Initiatives in Global HIV Trials, a global clinical influenza research network, to make more accurate case fatality ratio (CFR) estimates early in a future pandemic, an essential part of pandemic response.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29746631</PMID><DateCompleted><Year>2019</Year><Month>11</Month><Day>04</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>06</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1537-6591</ISSN><JournalIssue CitedMedium="Internet"><Volume>67</Volume><Issue>3</Issue><PubDate><Year>2018</Year><Month>07</Month><Day>18</Day></PubDate></JournalIssue><Title>Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</Title><ISOAbbreviation>Clin. Infect. Dis.</ISOAbbreviation></Journal><ArticleTitle>Using Clinical Research Networks to Assess Severity of an Emerging Influenza Pandemic.</ArticleTitle><Pagination><MedlinePgn>341-349</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/cid/ciy088</ELocationID><Abstract><AbstractText Label="Background">Early clinical severity assessments during the 2009 influenza A H1N1 pandemic (pH1N1) overestimated clinical severity due to selection bias and other factors. We retrospectively investigated how to use data from the International Network for Strategic Initiatives in Global HIV Trials, a global clinical influenza research network, to make more accurate case fatality ratio (CFR) estimates early in a future pandemic, an essential part of pandemic response.</AbstractText><AbstractText Label="Methods">We estimated the CFR of medically attended influenza (CFRMA) as the product of probability of hospitalization given confirmed outpatient influenza and the probability of death given hospitalization with confirmed influenza for the pandemic (2009-2011) and post-pandemic (2012-2015) periods. We used literature survey results on health-seeking behavior to convert that estimate to CFR among all infected persons (CFRAR).</AbstractText><AbstractText Label="Results">During the pandemic period, 5.0% (3.1%-6.9%) of 561 pH1N1-positive outpatients were hospitalized. Of 282 pH1N1-positive inpatients, 8.5% (5.7%-12.6%) died. CFRMA for pH1N1 was 0.4% (0.2%-0.6%) in the pandemic period 2009-2011 but declined 5-fold in young adults during the post-pandemic period compared to the level of seasonal influenza in the post-pandemic period 2012-2015. CFR for influenza-negative patients did not change over time. We estimated the 2009 pandemic CFRAR to be 0.025%, 16-fold lower than CFRMA.</AbstractText><AbstractText Label="Conclusions">Data from a clinical research network yielded accurate pandemic severity estimates, including increased severity among younger people. Going forward, clinical research networks with a global presence and standardized protocols would substantially aid rapid assessment of clinical severity.</AbstractText><AbstractText Label="Clinical Trials Registration">NCT01056354 and NCT01056185</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Simonsen</LastName><ForeName>Lone</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Rigshospitalet and Faculty of Health Sciences, University of Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Science and Environment, Roskilde University, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Higgs</LastName><ForeName>Elizabeth</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Taylor</LastName><ForeName>Robert J</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>Sage Analytica, Bethesda, Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wentworth</LastName><ForeName>Deborah</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Division of Biostatistics, University of Minnesota, Minneapolis.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cozzi-Lepri</LastName><ForeName>Al</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>University College, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pett</LastName><ForeName>Sarah</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Medical Research Council Clinical Trials Unit and Clinical Research Group, University College, London, United Kingdom.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Kirby Institute, University of New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dwyer</LastName><ForeName>Dominic E</ForeName><Initials>DE</Initials><AffiliationInfo><Affiliation>Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, Westmead Hospital and University of Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Davey</LastName><ForeName>Richard</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lynfield</LastName><ForeName>Ruth</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Minnesota Department of Health, St. Paul.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Losso</LastName><ForeName>Marcelo</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Hospital J.M. Ramos Mejía, Buenos Aires, Argentina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Morales</LastName><ForeName>Kathleen</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Sage Analytica, Bethesda, Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Glesby</LastName><ForeName>Marshall J</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>Weill Cornell Medical College, New York, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weckx</LastName><ForeName>Jozef</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Testumed Vereniging zonder winstoogmerk, Tessenderlo, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Carey</LastName><ForeName>Dianne</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>The Kirby Institute, University of New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lane</LastName><ForeName>Cliff</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lundgren</LastName><ForeName>Jens</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Rigshospitalet and Faculty of Health Sciences, University of Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>INSIGHT FLU002 and FLU003 Study Groups</CollectiveName></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>ClinicalTrials.gov</DataBankName><AccessionNumberList><AccessionNumber>NCT01056354</AccessionNumber><AccessionNumber>NCT01056185</AccessionNumber></AccessionNumberList></DataBank></DataBankList><GrantList CompleteYN="Y"><Grant><GrantID>MC_UU_12023/22</GrantID><Acronym>MRC_</Acronym><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>HHSN261200800001E</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016448">Multicenter Study</PublicationType><PublicationType UI="D064888">Observational Study</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Clin Infect Dis</MedlineTA><NlmUniqueID>9203213</NlmUniqueID><ISSNLinking>1058-4838</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015438" MajorTopicYN="Y">Health Behavior</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="Y">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012621" MajorTopicYN="N">Seasons</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012720" MajorTopicYN="N">Severity of Illness Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><InvestigatorList><Investigator ValidYN="Y"><LastName>Munroe</LastName><ForeName>David</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rappoport</LastName><ForeName>Claire</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schwarze</LastName><ForeName>Siegfried</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Aagaard</LastName><ForeName>Bitten</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Adzic</LastName><ForeName>Dejan</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Grarup</LastName><ForeName>Jesper</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Herrero</LastName><ForeName>Patricia</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jansson</LastName><ForeName>Per</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jakobsen</LastName><ForeName>Marie Louise</ForeName><Initials>ML</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jensen</LastName><ForeName>Birgitte</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jensen</LastName><ForeName>Karoline B</ForeName><Initials>KB</Initials></Investigator><Investigator ValidYN="Y"><LastName>Juncher</LastName><ForeName>Heidi</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kjær</LastName><ForeName>Jesper</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lundgren</LastName><ForeName>Jens</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lopez</LastName><ForeName>Paco</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mocroft</LastName><ForeName>Amanda</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pearson</LastName><ForeName>Mary</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Portas</LastName><ForeName>Begoña</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sabin</LastName><ForeName>Caroline</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tillmann</LastName><ForeName>Klaus</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Babiker</LastName><ForeName>Abdel</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Braimah</LastName><ForeName>Nafisah</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Collaco-Moraes</LastName><ForeName>Yolanda</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hudson</LastName><ForeName>Fleur</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kummeling</LastName><ForeName>Ischa</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pacciarini</LastName><ForeName>Filippo</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Paton</LastName><ForeName>Nick</ForeName><Initials>N</Initials></Investigator><Investigator 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ValidYN="Y"><LastName>Reilly</LastName><ForeName>Cavan</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schultz</LastName><ForeName>Terri</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Thompson</LastName><ForeName>Greg</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wyman</LastName><ForeName>Nicole</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Avihingsanon</LastName><ForeName>Anchalee</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Cassar</LastName><ForeName>Lara</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Charoentonpuban</LastName><ForeName>Kanlaya</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Emery</LastName><ForeName>Sean</ForeName><Initials>S</Initials></Investigator><Investigator 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ValidYN="Y"><LastName>Klinker</LastName><ForeName>Hartwig</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rockstroh</LastName><ForeName>Juergen</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Stephan</LastName><ForeName>Christoph</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Antoniadou</LastName><ForeName>Anastasia</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Koratzanis</LastName><ForeName>Georgios</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Koulouris</LastName><ForeName>Nikolaos</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Polixronopoulos</LastName><ForeName>Vlassis</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sambatakou</LastName><ForeName>Helen</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vasilopoulos</LastName><ForeName>Nikolaos</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Maagaard</LastName><ForeName>Anne</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mendo</LastName><ForeName>Fernando</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Salazar</LastName><ForeName>Raul</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bakowska</LastName><ForeName>Elzbieta</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Horban</LastName><ForeName>Andrzej</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Padayatchi</LastName><ForeName>Nesri</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dalmau</LastName><ForeName>David</ForeName><Initials>D</Initials></Investigator><Investigator 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ValidYN="Y"><LastName>Gordin</LastName><ForeName>Fred M</ForeName><Initials>FM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gulick</LastName><ForeName>Roy</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gurka</LastName><ForeName>David</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hodder</LastName><ForeName>Sally</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Markowitz</LastName><ForeName>Norman</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Novak</LastName><ForeName>Richard M</ForeName><Initials>RM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Paez</LastName><ForeName>Armando</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Patil</LastName><ForeName>Namrata</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Reboli</LastName><ForeName>Annette</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sands</LastName><ForeName>Michael</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schooley</LastName><ForeName>Robert</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Simon</LastName><ForeName>Gary L</ForeName><Initials>GL</Initials></Investigator><Investigator ValidYN="Y"><LastName>Temesgen</LastName><ForeName>Zelalem</ForeName><Initials>Z</Initials></Investigator><Investigator ValidYN="Y"><LastName>Timpone</LastName><ForeName>Joseph</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Uslan</LastName><ForeName>Daniel Z</ForeName><Initials>DZ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wade</LastName><ForeName>Barbara Heeter</ForeName><Initials>BH</Initials></Investigator></InvestigatorList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>08</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>04</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>5</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>11</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>5</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">29746631</ArticleId><ArticleId IdType="pii">4993975</ArticleId><ArticleId IdType="doi">10.1093/cid/ciy088</ArticleId><ArticleId IdType="pmc">PMC6248856</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>JAMA. 2009 Nov 4;302(17):1880-7</Citation><ArticleIdList><ArticleId IdType="pubmed">19822626</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Negl Trop Dis. 2015 Jul 16;9(7):e0003846</Citation><ArticleIdList><ArticleId IdType="pubmed">26181387</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2011 Jul;85(14):6923-9</Citation><ArticleIdList><ArticleId IdType="pubmed">21593168</ArticleId></ArticleIdList></Reference><Reference><Citation>Ann Saudi Med. 2010 Jan-Feb;30(1):11-4</Citation><ArticleIdList><ArticleId IdType="pubmed">20103952</ArticleId></ArticleIdList></Reference><Reference><Citation>Epidemiol Infect. 2010 Nov;138(11):1531-41</Citation><ArticleIdList><ArticleId IdType="pubmed">20594381</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2009 Nov 12;361(20):1935-44</Citation><ArticleIdList><ArticleId IdType="pubmed">19815859</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Infect Dis. 2011 Mar 16;11:68</Citation><ArticleIdList><ArticleId IdType="pubmed">21410965</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2013;8(2):e57121</Citation><ArticleIdList><ArticleId IdType="pubmed">23468921</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2013 Jan;19(1):85-91</Citation><ArticleIdList><ArticleId IdType="pubmed">23260039</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Epidemiol. 2014 Nov 15;180(10):1036-46</Citation><ArticleIdList><ArticleId IdType="pubmed">25255809</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2008 Jan 15;197(2):270-8</Citation><ArticleIdList><ArticleId IdType="pubmed">18194088</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2009 Jun 19;324(5934):1557-61</Citation><ArticleIdList><ArticleId IdType="pubmed">19433588</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2014 Jul 08;9(7):e101785</Citation><ArticleIdList><ArticleId IdType="pubmed">25004134</ArticleId></ArticleIdList></Reference><Reference><Citation>Euro Surveill. 2009 Aug 27;14(34):null</Citation><ArticleIdList><ArticleId IdType="pubmed">19712648</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Med. 2013 Nov;10(11):e1001558</Citation><ArticleIdList><ArticleId IdType="pubmed">24302890</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Curr. 2010 Mar 20;2:RRN1153</Citation><ArticleIdList><ArticleId IdType="pubmed">20352125</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Med. 2009 Dec;6(12):e1000207</Citation><ArticleIdList><ArticleId IdType="pubmed">19997612</ArticleId></ArticleIdList></Reference><Reference><Citation>Influenza Other Respir Viruses. 2011 May;5(3):148-56</Citation><ArticleIdList><ArticleId IdType="pubmed">21477133</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Epidemiol. 2013 Apr 15;177(8):834-40</Citation><ArticleIdList><ArticleId IdType="pubmed">23459950</ArticleId></ArticleIdList></Reference><Reference><Citation>Antimicrob Resist Infect Control. 2012 Sep 21;1(1):30</Citation><ArticleIdList><ArticleId IdType="pubmed">22995284</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2009 Jun 18;360(25):2605-15</Citation><ArticleIdList><ArticleId IdType="pubmed">19423869</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2016 Feb 15;213(4):574-8</Citation><ArticleIdList><ArticleId IdType="pubmed">26374911</ArticleId></ArticleIdList></Reference><Reference><Citation>Influenza Other Respir Viruses. 2013 Sep;7(5):872-86</Citation><ArticleIdList><ArticleId IdType="pubmed">23331969</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Respir Med. 2014 Jun;2(6):445-54</Citation><ArticleIdList><ArticleId IdType="pubmed">24717637</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2011 Jul 22;29 Suppl 2:B56-62</Citation><ArticleIdList><ArticleId IdType="pubmed">21757105</ArticleId></ArticleIdList></Reference><Reference><Citation>Wkly Epidemiol Rec. 2009 May 22;84(21):185-9</Citation><ArticleIdList><ArticleId IdType="pubmed">19462531</ArticleId></ArticleIdList></Reference><Reference><Citation>Epidemiology. 2013 Nov;24(6):830-41</Citation><ArticleIdList><ArticleId IdType="pubmed">24045719</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA. 2009 Nov 4;302(17):1896-902</Citation><ArticleIdList><ArticleId IdType="pubmed">19887665</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Infect Dis. 2012 Sep;12(9):687-95</Citation><ArticleIdList><ArticleId IdType="pubmed">22738893</ArticleId></ArticleIdList></Reference><Reference><Citation>Euro Surveill. 2009 Jul 30;14(30):19284</Citation><ArticleIdList><ArticleId 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