The 2009 A (H1N1) influenza virus pandemic: A review.
Identifieur interne : 001142 ( PubMed/Checkpoint ); précédent : 001141; suivant : 001143The 2009 A (H1N1) influenza virus pandemic: A review.
Auteurs : Marc P. Girard [France] ; John S. Tam ; Olga M. Assossou ; Marie Paule KienySource :
- Vaccine [ 1873-2518 ] ; 2010.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Antiviraux (pharmacologie), Coût de la maladie, Enfant, Enfant d'âge préscolaire, Facteurs de risque, Femelle, Flambées de maladies, Grippe humaine (), Grippe humaine (transmission), Grippe humaine (virologie), Grippe humaine (épidémiologie), Grossesse, Humains, Jeune adulte, Nourrisson, Sous-type H1N1 du virus de la grippe A (), Sous-type H1N1 du virus de la grippe A (génétique), Sous-type H1N1 du virus de la grippe A (immunologie), Suidae, Sujet âgé, Sujet âgé de 80 ans ou plus, Vaccins antigrippaux (immunologie).
- MESH :
- génétique : Sous-type H1N1 du virus de la grippe A.
- immunologie : Sous-type H1N1 du virus de la grippe A, Vaccins antigrippaux.
- pharmacologie : Antiviraux.
- virologie : Grippe humaine.
- épidémiologie : Grippe humaine.
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Coût de la maladie, Enfant, Enfant d'âge préscolaire, Facteurs de risque, Femelle, Flambées de maladies, Grippe humaine, Grossesse, Humains, Jeune adulte, Nourrisson, Sous-type H1N1 du virus de la grippe A, Suidae, Sujet âgé, Sujet âgé de 80 ans ou plus.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Animals, Antiviral Agents (pharmacology), Child, Child, Preschool, Cost of Illness, Disease Outbreaks, Female, Humans, Infant, Influenza A Virus, H1N1 Subtype (drug effects), Influenza A Virus, H1N1 Subtype (genetics), Influenza A Virus, H1N1 Subtype (immunology), Influenza Vaccines (immunology), Influenza, Human (epidemiology), Influenza, Human (prevention & control), Influenza, Human (transmission), Influenza, Human (virology), Middle Aged, Pregnancy, Risk Factors, Swine, Young Adult.
- MESH :
- chemical , immunology : Influenza Vaccines.
- chemical , pharmacology : Antiviral Agents.
- drug effects : Influenza A Virus, H1N1 Subtype.
- epidemiology : Influenza, Human.
- genetics : Influenza A Virus, H1N1 Subtype.
- immunology : Influenza A Virus, H1N1 Subtype.
- prevention & control : Influenza, Human.
- transmission : Influenza, Human.
- virology : Influenza, Human.
- Adolescent, Adult, Aged, Aged, 80 and over, Animals, Child, Child, Preschool, Cost of Illness, Disease Outbreaks, Female, Humans, Infant, Middle Aged, Pregnancy, Risk Factors, Swine, Young Adult.
Abstract
In March and early April 2009 a new swine-origin influenza virus (S-OIV), A (H1N1), emerged in Mexico and the USA. The virus quickly spread worldwide through human-to-human transmission. In view of the number of countries and communities which were reporting human cases, the World Health Organization raised the influenza pandemic alert to the highest level (level 6) on June 11, 2009. The propensity of the virus to primarily affect children, young adults and pregnant women, especially those with an underlying lung or cardiac disease condition, and the substantial increase in rate of hospitalizations, prompted the efforts of the pharmaceutical industry, including new manufacturers from China, Thailand, India and South America, to develop pandemic H1N1 influenza vaccines. All currently registered vaccines were tested for safety and immunogenicity in clinical trials on human volunteers. All were found to be safe and to elicit potentially protective antibody responses after the administration of a single dose of vaccine, including split inactivated vaccines with or without adjuvant, whole-virion vaccines and live-attenuated vaccines. The need for an increased surveillance of influenza virus circulation in swine is outlined.
DOI: 10.1016/j.vaccine.2010.05.031
PubMed: 20553769
Affiliations:
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pubmed:20553769Le document en format XML
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<front><div type="abstract" xml:lang="en">In March and early April 2009 a new swine-origin influenza virus (S-OIV), A (H1N1), emerged in Mexico and the USA. The virus quickly spread worldwide through human-to-human transmission. In view of the number of countries and communities which were reporting human cases, the World Health Organization raised the influenza pandemic alert to the highest level (level 6) on June 11, 2009. The propensity of the virus to primarily affect children, young adults and pregnant women, especially those with an underlying lung or cardiac disease condition, and the substantial increase in rate of hospitalizations, prompted the efforts of the pharmaceutical industry, including new manufacturers from China, Thailand, India and South America, to develop pandemic H1N1 influenza vaccines. All currently registered vaccines were tested for safety and immunogenicity in clinical trials on human volunteers. All were found to be safe and to elicit potentially protective antibody responses after the administration of a single dose of vaccine, including split inactivated vaccines with or without adjuvant, whole-virion vaccines and live-attenuated vaccines. The need for an increased surveillance of influenza virus circulation in swine is outlined.</div>
</front>
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<Abstract><AbstractText>In March and early April 2009 a new swine-origin influenza virus (S-OIV), A (H1N1), emerged in Mexico and the USA. The virus quickly spread worldwide through human-to-human transmission. In view of the number of countries and communities which were reporting human cases, the World Health Organization raised the influenza pandemic alert to the highest level (level 6) on June 11, 2009. The propensity of the virus to primarily affect children, young adults and pregnant women, especially those with an underlying lung or cardiac disease condition, and the substantial increase in rate of hospitalizations, prompted the efforts of the pharmaceutical industry, including new manufacturers from China, Thailand, India and South America, to develop pandemic H1N1 influenza vaccines. All currently registered vaccines were tested for safety and immunogenicity in clinical trials on human volunteers. All were found to be safe and to elicit potentially protective antibody responses after the administration of a single dose of vaccine, including split inactivated vaccines with or without adjuvant, whole-virion vaccines and live-attenuated vaccines. The need for an increased surveillance of influenza virus circulation in swine is outlined.</AbstractText>
<CopyrightInformation>Copyright 2010. Published by Elsevier Ltd.</CopyrightInformation>
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<ForeName>Marc P</ForeName>
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