PandemieGrippaleV1, PubMed, Checkpoint, bibRecord, 000159

Comparative effectiveness of H7N9 vaccines in healthy individuals.

Identifieur interne : 000159 ( PubMed/Checkpoint ); précédent : 000158; suivant : 000160

Comparative effectiveness of H7N9 vaccines in healthy individuals.

Auteurs : Dan Zheng [République populaire de Chine] ; Feixia Gao [République populaire de Chine] ; Cheng Zhao [République populaire de Chine] ; Yahong Ding [République populaire de Chine] ; Yemin Cao [République populaire de Chine] ; Tianhan Yang [République populaire de Chine] ; Xuesong Xu [République populaire de Chine] ; Ze Chen [République populaire de Chine]

Source :

Human vaccines & immunotherapeutics [ 2164-554X ] ; 2019.

RBID : pubmed:30148691

Descripteurs français

KwdFr :
- Adjuvants immunologiques (administration et posologie), Adjuvants immunologiques (normes), Essais contrôlés randomisés comme sujet, Femelle, Grippe humaine (), Humains, Immunogénicité des vaccins, Mâle, Sous-type H7N9 du virus de la grippe A, Vaccins antigrippaux (immunologie), Vaccins antigrippaux (normes).
MESH :
- administration et posologie : Adjuvants immunologiques.
- immunologie : Vaccins antigrippaux.
- normes : Adjuvants immunologiques, Vaccins antigrippaux.
- Essais contrôlés randomisés comme sujet, Femelle, Grippe humaine, Humains, Immunogénicité des vaccins, Mâle, Sous-type H7N9 du virus de la grippe A.

English descriptors

KwdEn :
- Adjuvants, Immunologic (administration & dosage), Adjuvants, Immunologic (standards), Female, Humans, Immunogenicity, Vaccine, Influenza A Virus, H7N9 Subtype, Influenza Vaccines (immunology), Influenza Vaccines (standards), Influenza, Human (prevention & control), Male, Randomized Controlled Trials as Topic.
MESH :
- chemical , administration & dosage : Adjuvants, Immunologic.
- chemical , immunology : Influenza Vaccines.
- chemical , standards : Adjuvants, Immunologic, Influenza Vaccines.
- prevention & control : Influenza, Human.
- Female, Humans, Immunogenicity, Vaccine, Influenza A Virus, H7N9 Subtype, Male, Randomized Controlled Trials as Topic.

Abstract

Avian H7N9 influenza viruses possess a potential pandemic threat to public health worldwide, and have caused severe infection and high mortality in humans. A series of clinical trials of H7N9 vaccines have been completed. Meta-analyses need to be performed to assess the immunogenicity and safety of H7N9 vaccines.

DOI: 10.1080/21645515.2018.1515454
PubMed: 30148691

Affiliations:

République populaire de Chine

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 000253
to stream PubMed, to step Curation: 000253

Links to Exploration step

pubmed:30148691

Le document en format XML

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<term>Humans</term>
<term>Immunogenicity, Vaccine</term>
<term>Influenza A Virus, H7N9 Subtype</term>
<term>Influenza Vaccines (immunology)</term>
<term>Influenza Vaccines (standards)</term>
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<term>Femelle</term>
<term>Grippe humaine ()</term>
<term>Humains</term>
<term>Immunogénicité des vaccins</term>
<term>Mâle</term>
<term>Sous-type H7N9 du virus de la grippe A</term>
<term>Vaccins antigrippaux (immunologie)</term>
<term>Vaccins antigrippaux (normes)</term>
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<front><div type="abstract" xml:lang="en">Avian H7N9 influenza viruses possess a potential pandemic threat to public health worldwide, and have caused severe infection and high mortality in humans. A series of clinical trials of H7N9 vaccines have been completed. Meta-analyses need to be performed to assess the immunogenicity and safety of H7N9 vaccines.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30148691</PMID>
<DateCompleted><Year>2020</Year>
<Month>02</Month>
<Day>18</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>03</Month>
<Day>09</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2164-554X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>15</Volume>
<Issue>1</Issue>
<PubDate><Year>2019</Year>
</PubDate>
</JournalIssue>
<Title>Human vaccines & immunotherapeutics</Title>
<ISOAbbreviation>Hum Vaccin Immunother</ISOAbbreviation>
</Journal>
<ArticleTitle>Comparative effectiveness of H7N9 vaccines in healthy individuals.</ArticleTitle>
<Pagination><MedlinePgn>80-90</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1080/21645515.2018.1515454</ELocationID>
<Abstract><AbstractText Label="BACKGROUND">Avian H7N9 influenza viruses possess a potential pandemic threat to public health worldwide, and have caused severe infection and high mortality in humans. A series of clinical trials of H7N9 vaccines have been completed. Meta-analyses need to be performed to assess the immunogenicity and safety of H7N9 vaccines.</AbstractText>
<AbstractText Label="METHODS">Database research with defined selection criteria was conducted in PubMed, Cochrane Central Register of Controlled Trials, the World Health Organization's International Clinical Trials Registry Platform, ClinicalTrials.gov, etc. Data from randomized clinical trials regarding the immunogenicity and safety of H7N9 vaccines were collected and meta-analyzed.</AbstractText>
<AbstractText Label="RESULTS">For non-adjuvanted H7N9 vaccines, high dose formulations induced limited immunogenicity and increased the risk of local and systemic adverse events, simultaneously. For adjuvanted H7N9 vaccines, on the one hand, ISCOMATRIX, MF59, AS03 and aluminium adjuvants applied in H7N9 vaccines could improve immune responses effectively, and non-aluminium adjuvants had superior performance in saving vaccine dose; on the other hand, aluminium adjuvant had the advantages of safety amongst these adjuvants applied in H7N9 vaccines.</AbstractText>
<AbstractText Label="CONCLUSION">H7N9 influenza vaccines with adjuvant might represent the optimal available option in an influenza pandemic, at present.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zheng</LastName>
<ForeName>Dan</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>a Department of Research and Development , Shanghai Institute of Biological Products , Shanghai , China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>b Shanghai TCM-Integrated Hospital , Shanghai University of Traditional Chinese Medicine , Shanghai , China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>c Department of Vascular Disease , Shanghai TCM-Integrated Institute of Vascular Disease , Shanghai , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gao</LastName>
<ForeName>Feixia</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>a Department of Research and Development , Shanghai Institute of Biological Products , Shanghai , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhao</LastName>
<ForeName>Cheng</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>b Shanghai TCM-Integrated Hospital , Shanghai University of Traditional Chinese Medicine , Shanghai , China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>c Department of Vascular Disease , Shanghai TCM-Integrated Institute of Vascular Disease , Shanghai , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ding</LastName>
<ForeName>Yahong</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>a Department of Research and Development , Shanghai Institute of Biological Products , Shanghai , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cao</LastName>
<ForeName>Yemin</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>b Shanghai TCM-Integrated Hospital , Shanghai University of Traditional Chinese Medicine , Shanghai , China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>c Department of Vascular Disease , Shanghai TCM-Integrated Institute of Vascular Disease , Shanghai , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yang</LastName>
<ForeName>Tianhan</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>a Department of Research and Development , Shanghai Institute of Biological Products , Shanghai , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Xu</LastName>
<ForeName>Xuesong</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>d Huadong Hospital Affiliated to Fudan University , Shanghai , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Ze</ForeName>
<Initials>Z</Initials>
<AffiliationInfo><Affiliation>a Department of Research and Development , Shanghai Institute of Biological Products , Shanghai , China.</Affiliation>
</AffiliationInfo>
</Author>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
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<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
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<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>09</Month>
<Day>14</Day>
</ArticleDate>
</Article>
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<MedlineTA>Hum Vaccin Immunother</MedlineTA>
<NlmUniqueID>101572652</NlmUniqueID>
<ISSNLinking>2164-5515</ISSNLinking>
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<NameOfSubstance UI="D000276">Adjuvants, Immunologic</NameOfSubstance>
</Chemical>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000071497" MajorTopicYN="N">Immunogenicity, Vaccine</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D064766" MajorTopicYN="Y">Influenza A Virus, H7N9 Subtype</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007252" MajorTopicYN="N">Influenza Vaccines</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
<QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016032" MajorTopicYN="N">Randomized Controlled Trials as Topic</DescriptorName>
</MeshHeading>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">H7N9 vaccine</Keyword>
<Keyword MajorTopicYN="Y">adjuvant</Keyword>
<Keyword MajorTopicYN="Y">immunogenicity</Keyword>
<Keyword MajorTopicYN="Y">meta-analysis</Keyword>
<Keyword MajorTopicYN="Y">safety</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2018</Year>
<Month>8</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>2</Month>
<Day>19</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2018</Year>
<Month>8</Month>
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<name sortKey="Chen, Ze" sort="Chen, Ze" uniqKey="Chen Z" first="Ze" last="Chen">Ze Chen</name>
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Comparative effectiveness of H7N9 vaccines in healthy individuals.

Comparative effectiveness of H7N9 vaccines in healthy individuals.

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