What the Paediatrician Needs to Know When Pandemic Influenza Arrives in Clinical Practice
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Auteurs :Source :
- Hot Topics in Infection and Immunity in Children IV ; 2008.
Abstract
Avian (H5N1) influenza or “bird ‘flu” has received considerable attention in both the medical literature and the mass media in the last few years. Despite the tabloids’ portrayal of an imminent threat, to date there have been relatively few cases in humans in spite of large numbers of infected poultry (Hien et al. 2004). However, this may be falsely reassuring. Most indications suggest that it is just a matter of time until the next influenza pandemic occurs (Osterholm 2005). In the words of the UK Chief Medical Officer: “most experts believe that it is not a question of whether there will be another severe influenza pandemic but when” (Department of Health 2005). Although experts are agreed that a future influenza pandemic is almost inevitable, its timing is unpredictable and it is uncertain whether the virus responsible will be H5N1 or another, novel, influenza strain (Osterholm 2005). A recent editorial described avian influenza as a “predicament of extraordinary proportions” (Anonymous 2006). The next influenza pandemic will have a dramatic impact on all levels of health care including the everyday work of doctors. This chapter focuses on the clinical aspects of pandemic influenza about which paediatricians need to be familiar.
Url:
DOI: 10.1007/978-0-387-73960-1_13
PubMed: 18193665
PubMed Central: 7123866
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<front><div type="abstract" xml:lang="en"><p>Avian (H5N1) influenza or “bird ‘flu” has received considerable attention in both the medical literature and the mass media in the last few years. Despite the tabloids’ portrayal of an imminent threat, to date there have been relatively few cases in humans in spite of large numbers of infected poultry (Hien et al. 2004). However, this may be falsely reassuring. Most indications suggest that it is just a matter of time until the next influenza pandemic occurs (Osterholm 2005). In the words of the UK Chief Medical Officer: “most experts believe that it is not a question of whether there will be another severe influenza pandemic but when” (Department of Health 2005). Although experts are agreed that a future influenza pandemic is almost inevitable, its timing is unpredictable and it is uncertain whether the virus responsible will be H5N1 or another, novel, influenza strain (Osterholm 2005). A recent editorial described avian influenza as a “predicament of extraordinary proportions” (Anonymous 2006). The next influenza pandemic will have a dramatic impact on all levels of health care including the everyday work of doctors. This chapter focuses on the clinical aspects of pandemic influenza about which paediatricians need to be familiar.</p>
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<pmc article-type="chapter-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="publisher-id">978-0-387-73960-1</journal-id>
<journal-id journal-id-type="doi">10.1007/978-0-387-73960-1</journal-id>
<journal-id journal-id-type="nlm-ta">Hot Topics in Infection and Immunity in Children IV</journal-id>
<journal-title-group><journal-title>Hot Topics in Infection and Immunity in Children IV</journal-title>
</journal-title-group>
<isbn publication-format="print">978-0-387-73959-5</isbn>
<isbn publication-format="electronic">978-0-387-73960-1</isbn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">18193665</article-id>
<article-id pub-id-type="pmc">7123866</article-id>
<article-id pub-id-type="publisher-id">13</article-id>
<article-id pub-id-type="doi">10.1007/978-0-387-73960-1_13</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>What the Paediatrician Needs to Know When Pandemic Influenza Arrives in Clinical Practice</article-title>
</title-group>
<contrib-group content-type="book editors"><contrib contrib-type="editor"><name><surname>Finn</surname>
<given-names>Adam</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="editor"><name><surname>Pollard</surname>
<given-names>Andrew J.</given-names>
</name>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<aff id="Aff1"><label>1</label>
<institution-wrap><institution-id institution-id-type="GRID">grid.5337.2</institution-id>
<institution-id institution-id-type="ISNI">0000000419367603</institution-id>
<institution>Institute of Child Life and Health UBHT Education Centre,</institution>
<institution>University of Bristol,</institution>
</institution-wrap>
Upper Maudlin Street, Bristol, BS2 8AE UK</aff>
<aff id="Aff2"><label>2</label>
<institution-wrap><institution-id institution-id-type="GRID">grid.4991.5</institution-id>
<institution-id institution-id-type="ISNI">0000000419368948</institution-id>
<institution>Department of Paediatrics,</institution>
<institution>University of Oxford,</institution>
</institution-wrap>
Level 4, John Radcliffe Hospital, Oxford, OX3 9DU UK</aff>
</contrib-group>
<contrib-group><contrib contrib-type="author"><name><surname>Ritz</surname>
<given-names>Nicole</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Curtis</surname>
<given-names>Nigel</given-names>
</name>
<address><phone>+61 3 9345 4545</phone>
<fax>+61 3 9345 6667</fax>
<email>nigel.curtis@rch.org.au</email>
</address>
<xref ref-type="aff" rid="Aff3"></xref>
</contrib>
<aff id="Aff3">Associate Professor, Department of Paediatrics, University of Melbourne, Head of Paediatric Infectious Diseases Unit, Department of General Medicine, Leader of Microbiology & Infectious Diseases Research Group, Murdoch Children's Research Institute, Royal Children's Hospital Melbourne, 4th Floor Front Building, Flemington Road, Parkville, VIC 3052 Australia</aff>
</contrib-group>
<pub-date pub-type="ppub"><year>2008</year>
</pub-date>
<volume>609</volume>
<fpage>164</fpage>
<lpage>184</lpage>
<permissions><copyright-statement>© Springer 2008</copyright-statement>
<license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p>
</license>
</permissions>
<abstract id="Abs1"><p>Avian (H5N1) influenza or “bird ‘flu” has received considerable attention in both the medical literature and the mass media in the last few years. Despite the tabloids’ portrayal of an imminent threat, to date there have been relatively few cases in humans in spite of large numbers of infected poultry (Hien et al. 2004). However, this may be falsely reassuring. Most indications suggest that it is just a matter of time until the next influenza pandemic occurs (Osterholm 2005). In the words of the UK Chief Medical Officer: “most experts believe that it is not a question of whether there will be another severe influenza pandemic but when” (Department of Health 2005). Although experts are agreed that a future influenza pandemic is almost inevitable, its timing is unpredictable and it is uncertain whether the virus responsible will be H5N1 or another, novel, influenza strain (Osterholm 2005). A recent editorial described avian influenza as a “predicament of extraordinary proportions” (Anonymous 2006). The next influenza pandemic will have a dramatic impact on all levels of health care including the everyday work of doctors. This chapter focuses on the clinical aspects of pandemic influenza about which paediatricians need to be familiar.</p>
</abstract>
<kwd-group xml:lang="en"><title>Keywords</title>
<kwd>Influenza Virus</kwd>
<kwd>Avian Influenza</kwd>
<kwd>Avian Influenza Virus</kwd>
<kwd>Pandemic Influenza</kwd>
<kwd>H5N1 Influenza</kwd>
</kwd-group>
<custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name>
<meta-value>© Springer New York 2008</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>
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