Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The relationship between encephalitis lethargica and influenza: A critical analysis</title><author><name sortKey="Mccall, Sherman" sort="Mccall, Sherman" uniqKey="Mccall S" first="Sherman" last="Mccall">Sherman Mccall</name><affiliation><nlm:aff id="A1"> Department of Clinical Pathology, US Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Vilensky, Joel A" sort="Vilensky, Joel A" uniqKey="Vilensky J" first="Joel A" last="Vilensky">Joel A. Vilensky</name><affiliation><nlm:aff id="A2"> Department of Anatomy and Cell Biology, Indiana University School of Medicine, Fort Wayne, Indiana, USA</nlm:aff></affiliation></author><author><name sortKey="Gilman, Sid" sort="Gilman, Sid" uniqKey="Gilman S" first="Sid" last="Gilman">Sid Gilman</name><affiliation><nlm:aff id="A3"> Department of Neurology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA</nlm:aff></affiliation></author><author><name sortKey="Taubenberger, Jeffery K" sort="Taubenberger, Jeffery K" uniqKey="Taubenberger J" first="Jeffery K" last="Taubenberger">Jeffery K. Taubenberger</name><affiliation><nlm:aff id="A4"> Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18569452</idno><idno type="pmc">2778472</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778472</idno><idno type="RBID">PMC:2778472</idno><idno type="doi">10.1080/13550280801995445</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">000567</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000567</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The relationship between encephalitis lethargica and influenza: A critical analysis</title><author><name sortKey="Mccall, Sherman" sort="Mccall, Sherman" uniqKey="Mccall S" first="Sherman" last="Mccall">Sherman Mccall</name><affiliation><nlm:aff id="A1"> Department of Clinical Pathology, US Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Vilensky, Joel A" sort="Vilensky, Joel A" uniqKey="Vilensky J" first="Joel A" last="Vilensky">Joel A. Vilensky</name><affiliation><nlm:aff id="A2"> Department of Anatomy and Cell Biology, Indiana University School of Medicine, Fort Wayne, Indiana, USA</nlm:aff></affiliation></author><author><name sortKey="Gilman, Sid" sort="Gilman, Sid" uniqKey="Gilman S" first="Sid" last="Gilman">Sid Gilman</name><affiliation><nlm:aff id="A3"> Department of Neurology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA</nlm:aff></affiliation></author><author><name sortKey="Taubenberger, Jeffery K" sort="Taubenberger, Jeffery K" uniqKey="Taubenberger J" first="Jeffery K" last="Taubenberger">Jeffery K. Taubenberger</name><affiliation><nlm:aff id="A4"> Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff></affiliation></author></analytic><series><title level="j">Journal of neurovirology</title><idno type="ISSN">1355-0284</idno><idno type="eISSN">1538-2443</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Since encephalitis lethargica’s (EL) prevalence in the 1920s, epidemiologic and clinical debate has persisted over whether EL was caused by, potentiated by, or merely coincident with the Spanish influenza pandemic. Epidemiologic analyses generally suggest that the disorders were coincidental. Beginning in the 1970s, modern experiments on archival brain samples mainly failed to confirm a direct relationship between influenza and EL. These experimental studies have technical limitations, e.g., the appropriateness of antibodies, polymerase chain reaction (PCR) primers and controls, and the extreme paucity and age of available material. These factors render the case against influenza less decisive than currently perceived. Nevertheless, there is little direct evidence supporting influenza in the etiology of EL. Almost 100 years after the EL epidemic, its etiology remains enigmatic, raising the possibility of a recurrence of EL in a future influenza pandemic.</p></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9508123</journal-id><journal-id journal-id-type="pubmed-jr-id">20381</journal-id><journal-id journal-id-type="nlm-ta">J Neurovirol</journal-id><journal-title>Journal of neurovirology</journal-title><issn pub-type="ppub">1355-0284</issn><issn pub-type="epub">1538-2443</issn></journal-meta><article-meta><article-id pub-id-type="pmid">18569452</article-id><article-id pub-id-type="pmc">2778472</article-id><article-id pub-id-type="doi">10.1080/13550280801995445</article-id><article-id pub-id-type="manuscript">NIHMS156516</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>The relationship between encephalitis lethargica and influenza: A critical analysis</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>McCall</surname><given-names>Sherman</given-names></name><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Vilensky</surname><given-names>Joel A</given-names></name><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Gilman</surname><given-names>Sid</given-names></name><xref rid="A3" ref-type="aff">3</xref></contrib><contrib contrib-type="author"><name><surname>Taubenberger</surname><given-names>Jeffery K</given-names></name><xref rid="A4" ref-type="aff">4</xref></contrib></contrib-group><aff id="A1"><label>1</label> Department of Clinical Pathology, US Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, USA</aff><aff id="A2"><label>2</label> Department of Anatomy and Cell Biology, Indiana University School of Medicine, Fort Wayne, Indiana, USA</aff><aff id="A3"><label>3</label> Department of Neurology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA</aff><aff id="A4"><label>4</label> Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA</aff><author-notes><corresp id="FN1">Address correspondence to Joel A. Vilensky, Indiana University School of Medicine, 2101 E. Coliseum Boulevard, Fort Wayne, IN 46805, USA. <email>vilensk@ipfw.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>2</day><month>11</month><year>2009</year></pub-date><pub-date pub-type="ppub"><month>5</month><year>2008</year></pub-date><pub-date pub-type="pmc-release"><day>17</day><month>11</month><year>2009</year></pub-date><volume>14</volume><issue>3</issue><fpage>177</fpage><lpage>185</lpage><abstract><p id="P1">Since encephalitis lethargica’s (EL) prevalence in the 1920s, epidemiologic and clinical debate has persisted over whether EL was caused by, potentiated by, or merely coincident with the Spanish influenza pandemic. Epidemiologic analyses generally suggest that the disorders were coincidental. Beginning in the 1970s, modern experiments on archival brain samples mainly failed to confirm a direct relationship between influenza and EL. These experimental studies have technical limitations, e.g., the appropriateness of antibodies, polymerase chain reaction (PCR) primers and controls, and the extreme paucity and age of available material. These factors render the case against influenza less decisive than currently perceived. Nevertheless, there is little direct evidence supporting influenza in the etiology of EL. Almost 100 years after the EL epidemic, its etiology remains enigmatic, raising the possibility of a recurrence of EL in a future influenza pandemic.</p></abstract><kwd-group><kwd>bird flu</kwd><kwd>epidemic encephalitis</kwd><kwd>sleepy sickness</kwd><kwd>von Economo’s disease</kwd></kwd-group><contract-num rid="AI1">ZIA AI000995-03
||AI</contract-num><contract-sponsor id="AI1">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</contract-sponsor></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 0005679 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 0005679 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= PandemieGrippaleV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.34. |  |