Safety of inactivated monovalent pandemic (H1N1) 2009 vaccination during pregnancy: A population-based study in Taiwan
Identifieur interne : 001D98 ( PascalFrancis/Curation ); précédent : 001D97; suivant : 001D99Safety of inactivated monovalent pandemic (H1N1) 2009 vaccination during pregnancy: A population-based study in Taiwan
Auteurs : Wan-Ting Huang [Taïwan] ; Fa-Wei Tang [Taïwan] ; Shu-Er Yang [Taïwan] ; Yi-Chien Chih [Taïwan] ; Jen-Hsiang Chuang [Taïwan]Source :
- Vaccine [ 0264-410X ] ; 2014.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Vaccination, Vaccin.
English descriptors
- KwdEn :
Abstract
Background: Pregnant women were prioritized for H1N1 vaccination during the 2009-2010 pandemic. Safety concerns exist with vaccinating pregnant women, particularly in their first trimesters. Methods: We linked computerized data on H1N1 vaccination, National Health Insurance, and Taiwan Birth Registry and identified events of spontaneous abortions (SABs) and all singleton births that occurred/delivered during November 1, 2009-September 30, 2010. The observation period for each case of SAB (6-19 weeks gestation) was divided into period at risk (1-28 days after vaccination) and control periods (the remaining person-days until SAB). The self-controlled case series method for truncated observational periods assessed the incidence rate ratio (IRR) of SAB during the 1-28 days compared with those in the control period. The case-control design matched each case of adverse fetal outcomes to up to 10 controls on fetal sex and year/month of pregnancy onset, and calculated matched odds ratio (OR) on H1N1 vaccination at <14 or ≥ 14 weeks gestation. Results: Sixty-five women with SAB had received H1N1 vaccination at 6-19 weeks gestation. The IRR of SAB for the risk period 1-28 days was 1.03 (95% confidence interval [CI] 0.55-1.93). Among the 147,294 live births and 1354 stillbirths, maternal H1N1 vaccine receipt at <14 weeks gestation was associated with significantly reduced likelihood of small for gestational age (SGA) birth (OR 0.72, 95% CI 0.61-0.84) and birth defect (OR 0.46,95% CI 0.22-1.00), whereas receipt at ≥14 weeks gestation was associated with significantly reduced likelihood of stillbirth (OR 0.63, 95% CI 0.46-0.86), prematurity (OR 0.90, 95% CI 0.83-0.97), low birth weight (OR 0.81, 95% CI 0.74-0.88), and SGA birth (OR 0.90, 95% CI 0.84-0.97). Conclusions: H1N1 vaccination during pregnancy did not increase risk of SAB or adverse fetal outcomes.
| pA |
|
|---|
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000021
Links to Exploration step
Pascal:14-0276947Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Safety of inactivated monovalent pandemic (H1N1) 2009 vaccination during pregnancy: A population-based study in Taiwan</title><author><name sortKey="Huang, Wan Ting" sort="Huang, Wan Ting" uniqKey="Huang W" first="Wan-Ting" last="Huang">Wan-Ting Huang</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation></author><author><name sortKey="Tang, Fa Wei" sort="Tang, Fa Wei" uniqKey="Tang F" first="Fa-Wei" last="Tang">Fa-Wei Tang</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation></author><author><name sortKey="Yang, Shu Er" sort="Yang, Shu Er" uniqKey="Yang S" first="Shu-Er" last="Yang">Shu-Er Yang</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation></author><author><name sortKey="Chih, Yi Chien" sort="Chih, Yi Chien" uniqKey="Chih Y" first="Yi-Chien" last="Chih">Yi-Chien Chih</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation></author><author><name sortKey="Chuang, Jen Hsiang" sort="Chuang, Jen Hsiang" uniqKey="Chuang J" first="Jen-Hsiang" last="Chuang">Jen-Hsiang Chuang</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Institute of Biomedical Informatics & Institute of Public Health, National Yang-Ming University, 155 Section 2, Linong Street</s1><s2>Taipei 11221</s2><s3>TWN</s3><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">14-0276947</idno><date when="2014">2014</date><idno type="stanalyst">PASCAL 14-0276947 INIST</idno><idno type="RBID">Pascal:14-0276947</idno><idno type="wicri:Area/PascalFrancis/Corpus">000021</idno><idno type="wicri:Area/PascalFrancis/Curation">001D98</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Safety of inactivated monovalent pandemic (H1N1) 2009 vaccination during pregnancy: A population-based study in Taiwan</title><author><name sortKey="Huang, Wan Ting" sort="Huang, Wan Ting" uniqKey="Huang W" first="Wan-Ting" last="Huang">Wan-Ting Huang</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation></author><author><name sortKey="Tang, Fa Wei" sort="Tang, Fa Wei" uniqKey="Tang F" first="Fa-Wei" last="Tang">Fa-Wei Tang</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation></author><author><name sortKey="Yang, Shu Er" sort="Yang, Shu Er" uniqKey="Yang S" first="Shu-Er" last="Yang">Shu-Er Yang</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation></author><author><name sortKey="Chih, Yi Chien" sort="Chih, Yi Chien" uniqKey="Chih Y" first="Yi-Chien" last="Chih">Yi-Chien Chih</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation></author><author><name sortKey="Chuang, Jen Hsiang" sort="Chuang, Jen Hsiang" uniqKey="Chuang J" first="Jen-Hsiang" last="Chuang">Jen-Hsiang Chuang</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Institute of Biomedical Informatics & Institute of Public Health, National Yang-Ming University, 155 Section 2, Linong Street</s1><s2>Taipei 11221</s2><s3>TWN</s3><sZ>5 aut.</sZ></inist:fA14><country>Taïwan</country></affiliation></author></analytic><series><title level="j" type="main">Vaccine</title><title level="j" type="abbreviated">Vaccine</title><idno type="ISSN">0264-410X</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Vaccine</title><title level="j" type="abbreviated">Vaccine</title><idno type="ISSN">0264-410X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Immunological adjuvant</term><term>Influenza A virus</term><term>Influenzavirus A(H1N1)</term><term>Pregnancy</term><term>Taiwan</term><term>Vaccination</term><term>Vaccine</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Virus grippal A</term><term>Vaccination</term><term>Gestation</term><term>Taiwan</term><term>Adjuvant immunologique</term><term>Vaccin</term><term>Virus grippal A(H1N1)</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Vaccination</term><term>Vaccin</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Pregnant women were prioritized for H1N1 vaccination during the 2009-2010 pandemic. Safety concerns exist with vaccinating pregnant women, particularly in their first trimesters. Methods: We linked computerized data on H1N1 vaccination, National Health Insurance, and Taiwan Birth Registry and identified events of spontaneous abortions (SABs) and all singleton births that occurred/delivered during November 1, 2009-September 30, 2010. The observation period for each case of SAB (6-19 weeks gestation) was divided into period at risk (1-28 days after vaccination) and control periods (the remaining person-days until SAB). The self-controlled case series method for truncated observational periods assessed the incidence rate ratio (IRR) of SAB during the 1-28 days compared with those in the control period. The case-control design matched each case of adverse fetal outcomes to up to 10 controls on fetal sex and year/month of pregnancy onset, and calculated matched odds ratio (OR) on H1N1 vaccination at <14 or ≥ 14 weeks gestation. Results: Sixty-five women with SAB had received H1N1 vaccination at 6-19 weeks gestation. The IRR of SAB for the risk period 1-28 days was 1.03 (95% confidence interval [CI] 0.55-1.93). Among the 147,294 live births and 1354 stillbirths, maternal H1N1 vaccine receipt at <14 weeks gestation was associated with significantly reduced likelihood of small for gestational age (SGA) birth (OR 0.72, 95% CI 0.61-0.84) and birth defect (OR 0.46,95% CI 0.22-1.00), whereas receipt at ≥14 weeks gestation was associated with significantly reduced likelihood of stillbirth (OR 0.63, 95% CI 0.46-0.86), prematurity (OR 0.90, 95% CI 0.83-0.97), low birth weight (OR 0.81, 95% CI 0.74-0.88), and SGA birth (OR 0.90, 95% CI 0.84-0.97). Conclusions: H1N1 vaccination during pregnancy did not increase risk of SAB or adverse fetal outcomes.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0264-410X</s0></fA01><fA02 i1="01"><s0>VACCDE</s0></fA02><fA03 i2="1"><s0>Vaccine</s0></fA03><fA05><s2>32</s2></fA05><fA06><s2>48</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Safety of inactivated monovalent pandemic (H1N1) 2009 vaccination during pregnancy: A population-based study in Taiwan</s1></fA08><fA11 i1="01" i2="1"><s1>HUANG (Wan-Ting)</s1></fA11><fA11 i1="02" i2="1"><s1>TANG (Fa-Wei)</s1></fA11><fA11 i1="03" i2="1"><s1>YANG (Shu-Er)</s1></fA11><fA11 i1="04" i2="1"><s1>CHIH (Yi-Chien)</s1></fA11><fA11 i1="05" i2="1"><s1>CHUANG (Jen-Hsiang)</s1></fA11><fA14 i1="01"><s1>Taiwan Centers for Disease Control, 6 Linsen S. Road</s1><s2>Taipei 10050</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></fA14><fA14 i1="02"><s1>Institute of Biomedical Informatics & Institute of Public Health, National Yang-Ming University, 155 Section 2, Linong Street</s1><s2>Taipei 11221</s2><s3>TWN</s3><sZ>5 aut.</sZ></fA14><fA20><s1>6463-6468</s1></fA20><fA21><s1>2014</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>20289</s2><s5>354000502696130230</s5></fA43><fA44><s0>0000</s0><s1>© 2014 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>35 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>14-0276947</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Vaccine</s0></fA64><fA66 i1="01"><s0>GBR</s0></fA66><fC01 i1="01" l="ENG"><s0>Background: Pregnant women were prioritized for H1N1 vaccination during the 2009-2010 pandemic. Safety concerns exist with vaccinating pregnant women, particularly in their first trimesters. Methods: We linked computerized data on H1N1 vaccination, National Health Insurance, and Taiwan Birth Registry and identified events of spontaneous abortions (SABs) and all singleton births that occurred/delivered during November 1, 2009-September 30, 2010. The observation period for each case of SAB (6-19 weeks gestation) was divided into period at risk (1-28 days after vaccination) and control periods (the remaining person-days until SAB). The self-controlled case series method for truncated observational periods assessed the incidence rate ratio (IRR) of SAB during the 1-28 days compared with those in the control period. The case-control design matched each case of adverse fetal outcomes to up to 10 controls on fetal sex and year/month of pregnancy onset, and calculated matched odds ratio (OR) on H1N1 vaccination at <14 or ≥ 14 weeks gestation. Results: Sixty-five women with SAB had received H1N1 vaccination at 6-19 weeks gestation. The IRR of SAB for the risk period 1-28 days was 1.03 (95% confidence interval [CI] 0.55-1.93). Among the 147,294 live births and 1354 stillbirths, maternal H1N1 vaccine receipt at <14 weeks gestation was associated with significantly reduced likelihood of small for gestational age (SGA) birth (OR 0.72, 95% CI 0.61-0.84) and birth defect (OR 0.46,95% CI 0.22-1.00), whereas receipt at ≥14 weeks gestation was associated with significantly reduced likelihood of stillbirth (OR 0.63, 95% CI 0.46-0.86), prematurity (OR 0.90, 95% CI 0.83-0.97), low birth weight (OR 0.81, 95% CI 0.74-0.88), and SGA birth (OR 0.90, 95% CI 0.84-0.97). Conclusions: H1N1 vaccination during pregnancy did not increase risk of SAB or adverse fetal outcomes.</s0></fC01><fC02 i1="01" i2="X"><s0>002A05F04</s0></fC02><fC02 i1="02" i2="X"><s0>002A05C10</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Virus grippal A</s0><s2>NW</s2><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Influenza A virus</s0><s2>NW</s2><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Influenza A virus</s0><s2>NW</s2><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Vaccination</s0><s5>05</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Vaccination</s0><s5>05</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Vacunación</s0><s5>05</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Gestation</s0><s5>06</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Pregnancy</s0><s5>06</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Gestación</s0><s5>06</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Taiwan</s0><s2>NG</s2><s5>07</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Taiwan</s0><s2>NG</s2><s5>07</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Taiwan</s0><s2>NG</s2><s5>07</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Adjuvant immunologique</s0><s5>08</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Immunological adjuvant</s0><s5>08</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Coadyuvante inmunológico</s0><s5>08</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Vaccin</s0><s5>09</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Vaccine</s0><s5>09</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Vacuna</s0><s5>09</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Virus grippal A(H1N1)</s0><s4>CD</s4><s5>96</s5></fC03><fC03 i1="07" i2="X" l="ENG"><s0>Influenzavirus A(H1N1)</s0><s4>CD</s4><s5>96</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Influenzavirus A</s0><s2>NW</s2></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Influenzavirus A</s0><s2>NW</s2></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Influenzavirus A</s0><s2>NW</s2></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Orthomyxoviridae</s0><s2>NW</s2></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Orthomyxoviridae</s0><s2>NW</s2></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Orthomyxoviridae</s0><s2>NW</s2></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Virus</s0><s2>NW</s2></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Virus</s0><s2>NW</s2></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Virus</s0><s2>NW</s2></fC07><fC07 i1="04" i2="X" l="FRE"><s0>Asie</s0><s2>NG</s2></fC07><fC07 i1="04" i2="X" l="ENG"><s0>Asia</s0><s2>NG</s2></fC07><fC07 i1="04" i2="X" l="SPA"><s0>Asia</s0><s2>NG</s2></fC07><fC07 i1="05" i2="X" l="FRE"><s0>Extrême Orient</s0><s2>NG</s2><s5>13</s5></fC07><fC07 i1="05" i2="X" l="ENG"><s0>Far east</s0><s2>NG</s2><s5>13</s5></fC07><fC07 i1="05" i2="X" l="SPA"><s0>Extremo Oriente</s0><s2>NG</s2><s5>13</s5></fC07><fC07 i1="06" i2="X" l="FRE"><s0>Zone subtropicale</s0><s5>16</s5></fC07><fC07 i1="06" i2="X" l="ENG"><s0>Subtropical zone</s0><s5>16</s5></fC07><fC07 i1="06" i2="X" l="SPA"><s0>Zona subtropical</s0><s5>16</s5></fC07><fN21><s1>349</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard></inist></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/PascalFrancis/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001D98 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Curation/biblio.hfd -nk 001D98 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= PandemieGrippaleV1
|flux= PascalFrancis
|étape= Curation
|type= RBID
|clé= Pascal:14-0276947
|texte= Safety of inactivated monovalent pandemic (H1N1) 2009 vaccination during pregnancy: A population-based study in Taiwan
}}
| This area was generated with Dilib version V0.6.34. |  |