Benefit of Conjugate Pneumococcal Vaccination in Preventing Influenza Hospitalization in Children: A Case-control Study
Identifieur interne : 000313 ( PascalFrancis/Corpus ); précédent : 000312; suivant : 000314Benefit of Conjugate Pneumococcal Vaccination in Preventing Influenza Hospitalization in Children: A Case-control Study
Auteurs : Angela Dominguez ; Jesús Castilla ; Pere Godoy ; Miguel Delgado-Rodriguez ; Marc Saez ; Núria Soldevila ; Jenaro Astray ; José María Mayoral ; Vicente Martin ; José María Quintana ; Fernando Gonzalez-Candelas ; Juan Carlos Galan ; Sonia Tamames ; Ady Castro Acosta ; Maretva Baricot ; Olatz Garin ; Juan Jose Garcia ; Fernando Moraga ; Tomás PumarolaSource :
- The Pediatric infectious disease journal [ 0891-3668 ] ; 2013.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Background: The pneumococcal conjugate vaccine (PCV) might prevent hospitalizations in children because of the role of Streptococcus pneumoniae in the complications of influenza infection. We investigated the benefit of PCV vaccination in preventing influenza hospitalization in children <5 years of age during the 2009 to 2010 pandemic wave and the 2010 to 2011 influenza epidemic in Spain. Methods: A multicenter matched case-control study was undertaken in 27 hospitals from 7 Spanish regions between July 2009 and April 2011. A case was defined as a hospitalized patient between 6 months and 5 years of age with influenza virus infection confirmed by real-time reverse-transcription polymerase chain reaction. We selected 2 matched controls for each case from patients with unplanned hospital admission for reasons other than acute respiratory infection or influenza-like illness. Cases and controls were matched according to age, date of hospitalization and province of residence. Crude and adjusted odds ratios were calculated for associations between influenza hospitalization and PCV vaccination. Results: One hundred ninety-four cases and 342 controls were included in the study. In the 2009 to 2010 pandemic wave, the adjusted benefit in preventing hospitalization was 48% (95% confidence interval: 1 to 76) in fully vaccinated children compared with -79% (95% confidence interval: -341 to 27) in the 2010 to 2011 influenza season. Conclusions: The results obtained suggest that, in children <5 years of age, PCV vaccination reduced hospitalization during the 2009 to 2010 pandemic wave. By contrast, there was no observed benefit of vaccination in the 2010 to 2011 influenza season.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
| pA |
|
|---|
Format Inist (serveur)
| NO : | PASCAL 13-0152004 INIST |
|---|---|
| ET : | Benefit of Conjugate Pneumococcal Vaccination in Preventing Influenza Hospitalization in Children: A Case-control Study |
| AU : | DOMINGUEZ (Angela); CASTILLA (Jesús); GODOY (Pere); DELGADO-RODRIGUEZ (Miguel); SAEZ (Marc); SOLDEVILA (Núria); ASTRAY (Jenaro); MAYORAL (José María); MARTIN (Vicente); QUINTANA (José María); GONZALEZ-CANDELAS (Fernando); CARLOS GALAN (Juan); TAMAMES (Sonia); CASTRO ACOSTA (Ady); BARICOT (Maretva); GARIN (Olatz); JOSE GARCIA (Juan); MORAGA (Fernando); PUMAROLA (Tomás) |
| AF : | Department de Salut Publica, Universitat de Barcelona/Barcelona/Espagne (1 aut.); CIBER Epidemiologia y Salud Pública/Madrid/Espagne (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut., 9 aut., 10 aut., 11 aut., 12 aut., 15 aut., 16 aut.); Instituto de Salud Publica de Navarra/Pamplona/Espagne (2 aut.); Department de Salut, Generalitat de Catalunya/Barcelona/Espagne (3 aut.); Universidad de Jaen, Jaen; IIGRECS, Universitat de Girona/Girona/Espagne (4 aut.); Area de Epidemiologia, Comunidad de Madrid/Madrid/Espagne (7 aut.); Servicio de Vigilancia de Andalucia/Espagne (8 aut.); Instituto de Biomedicina, Universidad de Leon/León/Espagne (9 aut.); Unidad de Investigación, Hospital Galdakao-Usansolo/San Sebastian/Espagne (10 aut.); Centro Superior de Investigación en Salud Pública, Universidad de Valencia/Espagne (11 aut.); Hospital Universitario Ramón y Cajal/Madrid/Espagne (12 aut.); Dirección General de Salud Pública e Investigación, Desarrollo e Innovación, Junta de Castilla y León/Espagne (13 aut.); CIBER Enfermedades Respiratorias/Espagne (14 aut.); Institut Municipal d' Investigació Mèdica/Barcelona/Espagne (16 aut.); Hospital Universitari San Joan de Déu/Esplugues/Espagne (17 aut.); Hospital Universitari Vall d' Hebrón/Espagne (18 aut.); Red Española de Investigación en Patologia Infecciosa/Espagne (19 aut.) |
| DT : | Publication en série; Niveau analytique |
| SO : | The Pediatric infectious disease journal; ISSN 0891-3668; Coden PIDJEV; Etats-Unis; Da. 2013; Vol. 32; No. 4; Pp. 330-334; Bibl. 36 ref. |
| LA : | Anglais |
| EA : | Background: The pneumococcal conjugate vaccine (PCV) might prevent hospitalizations in children because of the role of Streptococcus pneumoniae in the complications of influenza infection. We investigated the benefit of PCV vaccination in preventing influenza hospitalization in children <5 years of age during the 2009 to 2010 pandemic wave and the 2010 to 2011 influenza epidemic in Spain. Methods: A multicenter matched case-control study was undertaken in 27 hospitals from 7 Spanish regions between July 2009 and April 2011. A case was defined as a hospitalized patient between 6 months and 5 years of age with influenza virus infection confirmed by real-time reverse-transcription polymerase chain reaction. We selected 2 matched controls for each case from patients with unplanned hospital admission for reasons other than acute respiratory infection or influenza-like illness. Cases and controls were matched according to age, date of hospitalization and province of residence. Crude and adjusted odds ratios were calculated for associations between influenza hospitalization and PCV vaccination. Results: One hundred ninety-four cases and 342 controls were included in the study. In the 2009 to 2010 pandemic wave, the adjusted benefit in preventing hospitalization was 48% (95% confidence interval: 1 to 76) in fully vaccinated children compared with -79% (95% confidence interval: -341 to 27) in the 2010 to 2011 influenza season. Conclusions: The results obtained suggest that, in children <5 years of age, PCV vaccination reduced hospitalization during the 2009 to 2010 pandemic wave. By contrast, there was no observed benefit of vaccination in the 2010 to 2011 influenza season. |
| CC : | 002B05B02N; 002B05C02C |
| FD : | Pneumococcie; Grippe A; Immunoprophylaxie; Vaccination; Prévention; Hospitalisation; Streptococcus pneumoniae; Enfant; Etude cas témoin; Vaccin associé; Variation saisonnière; Pédiatrie; Pandémie |
| FG : | Streptococcie; Bactériose; Infection; Virose; Streptococcaceae; Micrococcales; Bactérie; Homme; Epidémiologie |
| ED : | Pneumococcal infection; Influenza A; Immunoprophylaxis; Vaccination; Prevention; Hospitalization; Streptococcus pneumoniae; Child; Case control study; Mixed vaccine; Seasonal variation; Pediatrics |
| EG : | Streptococcal infection; Bacteriosis; Infection; Viral disease; Streptococcaceae; Micrococcales; Bacteria; Human; Epidemiology |
| SD : | Neumococia; Gripe A; Inmunoprofilaxia; Vacunación; Prevención; Hospitalización; Streptococcus pneumoniae; Niño; Estudio caso control; Vacuna mixta; Variación estacional; Pediatría |
| LO : | INIST-20356.354000503744960050 |
| ID : | 13-0152004 |
Links to Exploration step
Pascal:13-0152004Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Benefit of Conjugate Pneumococcal Vaccination in Preventing Influenza Hospitalization in Children: A Case-control Study</title><author><name sortKey="Dominguez, Angela" sort="Dominguez, Angela" uniqKey="Dominguez A" first="Angela" last="Dominguez">Angela Dominguez</name><affiliation><inist:fA14 i1="01"><s1>Department de Salut Publica, Universitat de Barcelona</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>1 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Castilla, Jesus" sort="Castilla, Jesus" uniqKey="Castilla J" first="Jesús" last="Castilla">Jesús Castilla</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="03"><s1>Instituto de Salud Publica de Navarra</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>2 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Godoy, Pere" sort="Godoy, Pere" uniqKey="Godoy P" first="Pere" last="Godoy">Pere Godoy</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="04"><s1>Department de Salut, Generalitat de Catalunya</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>3 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Delgado Rodriguez, Miguel" sort="Delgado Rodriguez, Miguel" uniqKey="Delgado Rodriguez M" first="Miguel" last="Delgado-Rodriguez">Miguel Delgado-Rodriguez</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="05"><s1>Universidad de Jaen, Jaen; IIGRECS, Universitat de Girona</s1><s2>Girona</s2><s3>ESP</s3><sZ>4 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Saez, Marc" sort="Saez, Marc" uniqKey="Saez M" first="Marc" last="Saez">Marc Saez</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Soldevila, Nuria" sort="Soldevila, Nuria" uniqKey="Soldevila N" first="Núria" last="Soldevila">Núria Soldevila</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Astray, Jenaro" sort="Astray, Jenaro" uniqKey="Astray J" first="Jenaro" last="Astray">Jenaro Astray</name><affiliation><inist:fA14 i1="06"><s1>Area de Epidemiologia, Comunidad de Madrid</s1><s2>Madrid</s2><s3>ESP</s3><sZ>7 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Mayoral, Jose Maria" sort="Mayoral, Jose Maria" uniqKey="Mayoral J" first="José María" last="Mayoral">José María Mayoral</name><affiliation><inist:fA14 i1="07"><s1>Servicio de Vigilancia de Andalucia</s1><s3>ESP</s3><sZ>8 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Martin, Vicente" sort="Martin, Vicente" uniqKey="Martin V" first="Vicente" last="Martin">Vicente Martin</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="08"><s1>Instituto de Biomedicina, Universidad de Leon</s1><s2>León</s2><s3>ESP</s3><sZ>9 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Quintana, Jose Maria" sort="Quintana, Jose Maria" uniqKey="Quintana J" first="José María" last="Quintana">José María Quintana</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="09"><s1>Unidad de Investigación, Hospital Galdakao-Usansolo</s1><s2>San Sebastian</s2><s3>ESP</s3><sZ>10 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Gonzalez Candelas, Fernando" sort="Gonzalez Candelas, Fernando" uniqKey="Gonzalez Candelas F" first="Fernando" last="Gonzalez-Candelas">Fernando Gonzalez-Candelas</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="10"><s1>Centro Superior de Investigación en Salud Pública, Universidad de Valencia</s1><s3>ESP</s3><sZ>11 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Carlos Galan, Juan" sort="Carlos Galan, Juan" uniqKey="Carlos Galan J" first="Juan" last="Carlos Galan">Juan Carlos Galan</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="11"><s1>Hospital Universitario Ramón y Cajal</s1><s2>Madrid</s2><s3>ESP</s3><sZ>12 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Tamames, Sonia" sort="Tamames, Sonia" uniqKey="Tamames S" first="Sonia" last="Tamames">Sonia Tamames</name><affiliation><inist:fA14 i1="12"><s1>Dirección General de Salud Pública e Investigación, Desarrollo e Innovación, Junta de Castilla y León</s1><s3>ESP</s3><sZ>13 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Castro Acosta, Ady" sort="Castro Acosta, Ady" uniqKey="Castro Acosta A" first="Ady" last="Castro Acosta">Ady Castro Acosta</name><affiliation><inist:fA14 i1="13"><s1>CIBER Enfermedades Respiratorias</s1><s3>ESP</s3><sZ>14 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Baricot, Maretva" sort="Baricot, Maretva" uniqKey="Baricot M" first="Maretva" last="Baricot">Maretva Baricot</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Garin, Olatz" sort="Garin, Olatz" uniqKey="Garin O" first="Olatz" last="Garin">Olatz Garin</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="14"><s1>Institut Municipal d' Investigació Mèdica</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>16 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Jose Garcia, Juan" sort="Jose Garcia, Juan" uniqKey="Jose Garcia J" first="Juan" last="Jose Garcia">Juan Jose Garcia</name><affiliation><inist:fA14 i1="15"><s1>Hospital Universitari San Joan de Déu</s1><s2>Esplugues</s2><s3>ESP</s3><sZ>17 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Moraga, Fernando" sort="Moraga, Fernando" uniqKey="Moraga F" first="Fernando" last="Moraga">Fernando Moraga</name><affiliation><inist:fA14 i1="16"><s1>Hospital Universitari Vall d' Hebrón</s1><s3>ESP</s3><sZ>18 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Pumarola, Tomas" sort="Pumarola, Tomas" uniqKey="Pumarola T" first="Tomás" last="Pumarola">Tomás Pumarola</name><affiliation><inist:fA14 i1="17"><s1>Red Española de Investigación en Patologia Infecciosa</s1><s3>ESP</s3><sZ>19 aut.</sZ></inist:fA14></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">13-0152004</idno><date when="2013">2013</date><idno type="stanalyst">PASCAL 13-0152004 INIST</idno><idno type="RBID">Pascal:13-0152004</idno><idno type="wicri:Area/PascalFrancis/Corpus">000313</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Benefit of Conjugate Pneumococcal Vaccination in Preventing Influenza Hospitalization in Children: A Case-control Study</title><author><name sortKey="Dominguez, Angela" sort="Dominguez, Angela" uniqKey="Dominguez A" first="Angela" last="Dominguez">Angela Dominguez</name><affiliation><inist:fA14 i1="01"><s1>Department de Salut Publica, Universitat de Barcelona</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>1 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Castilla, Jesus" sort="Castilla, Jesus" uniqKey="Castilla J" first="Jesús" last="Castilla">Jesús Castilla</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="03"><s1>Instituto de Salud Publica de Navarra</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>2 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Godoy, Pere" sort="Godoy, Pere" uniqKey="Godoy P" first="Pere" last="Godoy">Pere Godoy</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="04"><s1>Department de Salut, Generalitat de Catalunya</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>3 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Delgado Rodriguez, Miguel" sort="Delgado Rodriguez, Miguel" uniqKey="Delgado Rodriguez M" first="Miguel" last="Delgado-Rodriguez">Miguel Delgado-Rodriguez</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="05"><s1>Universidad de Jaen, Jaen; IIGRECS, Universitat de Girona</s1><s2>Girona</s2><s3>ESP</s3><sZ>4 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Saez, Marc" sort="Saez, Marc" uniqKey="Saez M" first="Marc" last="Saez">Marc Saez</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Soldevila, Nuria" sort="Soldevila, Nuria" uniqKey="Soldevila N" first="Núria" last="Soldevila">Núria Soldevila</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Astray, Jenaro" sort="Astray, Jenaro" uniqKey="Astray J" first="Jenaro" last="Astray">Jenaro Astray</name><affiliation><inist:fA14 i1="06"><s1>Area de Epidemiologia, Comunidad de Madrid</s1><s2>Madrid</s2><s3>ESP</s3><sZ>7 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Mayoral, Jose Maria" sort="Mayoral, Jose Maria" uniqKey="Mayoral J" first="José María" last="Mayoral">José María Mayoral</name><affiliation><inist:fA14 i1="07"><s1>Servicio de Vigilancia de Andalucia</s1><s3>ESP</s3><sZ>8 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Martin, Vicente" sort="Martin, Vicente" uniqKey="Martin V" first="Vicente" last="Martin">Vicente Martin</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="08"><s1>Instituto de Biomedicina, Universidad de Leon</s1><s2>León</s2><s3>ESP</s3><sZ>9 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Quintana, Jose Maria" sort="Quintana, Jose Maria" uniqKey="Quintana J" first="José María" last="Quintana">José María Quintana</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="09"><s1>Unidad de Investigación, Hospital Galdakao-Usansolo</s1><s2>San Sebastian</s2><s3>ESP</s3><sZ>10 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Gonzalez Candelas, Fernando" sort="Gonzalez Candelas, Fernando" uniqKey="Gonzalez Candelas F" first="Fernando" last="Gonzalez-Candelas">Fernando Gonzalez-Candelas</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="10"><s1>Centro Superior de Investigación en Salud Pública, Universidad de Valencia</s1><s3>ESP</s3><sZ>11 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Carlos Galan, Juan" sort="Carlos Galan, Juan" uniqKey="Carlos Galan J" first="Juan" last="Carlos Galan">Juan Carlos Galan</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="11"><s1>Hospital Universitario Ramón y Cajal</s1><s2>Madrid</s2><s3>ESP</s3><sZ>12 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Tamames, Sonia" sort="Tamames, Sonia" uniqKey="Tamames S" first="Sonia" last="Tamames">Sonia Tamames</name><affiliation><inist:fA14 i1="12"><s1>Dirección General de Salud Pública e Investigación, Desarrollo e Innovación, Junta de Castilla y León</s1><s3>ESP</s3><sZ>13 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Castro Acosta, Ady" sort="Castro Acosta, Ady" uniqKey="Castro Acosta A" first="Ady" last="Castro Acosta">Ady Castro Acosta</name><affiliation><inist:fA14 i1="13"><s1>CIBER Enfermedades Respiratorias</s1><s3>ESP</s3><sZ>14 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Baricot, Maretva" sort="Baricot, Maretva" uniqKey="Baricot M" first="Maretva" last="Baricot">Maretva Baricot</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Garin, Olatz" sort="Garin, Olatz" uniqKey="Garin O" first="Olatz" last="Garin">Olatz Garin</name><affiliation><inist:fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="14"><s1>Institut Municipal d' Investigació Mèdica</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>16 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Jose Garcia, Juan" sort="Jose Garcia, Juan" uniqKey="Jose Garcia J" first="Juan" last="Jose Garcia">Juan Jose Garcia</name><affiliation><inist:fA14 i1="15"><s1>Hospital Universitari San Joan de Déu</s1><s2>Esplugues</s2><s3>ESP</s3><sZ>17 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Moraga, Fernando" sort="Moraga, Fernando" uniqKey="Moraga F" first="Fernando" last="Moraga">Fernando Moraga</name><affiliation><inist:fA14 i1="16"><s1>Hospital Universitari Vall d' Hebrón</s1><s3>ESP</s3><sZ>18 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Pumarola, Tomas" sort="Pumarola, Tomas" uniqKey="Pumarola T" first="Tomás" last="Pumarola">Tomás Pumarola</name><affiliation><inist:fA14 i1="17"><s1>Red Española de Investigación en Patologia Infecciosa</s1><s3>ESP</s3><sZ>19 aut.</sZ></inist:fA14></affiliation></author></analytic><series><title level="j" type="main">The Pediatric infectious disease journal</title><title level="j" type="abbreviated">Pediatr. infect. dis. j.</title><idno type="ISSN">0891-3668</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">The Pediatric infectious disease journal</title><title level="j" type="abbreviated">Pediatr. infect. dis. j.</title><idno type="ISSN">0891-3668</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Case control study</term><term>Child</term><term>Hospitalization</term><term>Immunoprophylaxis</term><term>Influenza A</term><term>Mixed vaccine</term><term>Pediatrics</term><term>Pneumococcal infection</term><term>Prevention</term><term>Seasonal variation</term><term>Streptococcus pneumoniae</term><term>Vaccination</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Pneumococcie</term><term>Grippe A</term><term>Immunoprophylaxie</term><term>Vaccination</term><term>Prévention</term><term>Hospitalisation</term><term>Streptococcus pneumoniae</term><term>Enfant</term><term>Etude cas témoin</term><term>Vaccin associé</term><term>Variation saisonnière</term><term>Pédiatrie</term><term>Pandémie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: The pneumococcal conjugate vaccine (PCV) might prevent hospitalizations in children because of the role of Streptococcus pneumoniae in the complications of influenza infection. We investigated the benefit of PCV vaccination in preventing influenza hospitalization in children <5 years of age during the 2009 to 2010 pandemic wave and the 2010 to 2011 influenza epidemic in Spain. Methods: A multicenter matched case-control study was undertaken in 27 hospitals from 7 Spanish regions between July 2009 and April 2011. A case was defined as a hospitalized patient between 6 months and 5 years of age with influenza virus infection confirmed by real-time reverse-transcription polymerase chain reaction. We selected 2 matched controls for each case from patients with unplanned hospital admission for reasons other than acute respiratory infection or influenza-like illness. Cases and controls were matched according to age, date of hospitalization and province of residence. Crude and adjusted odds ratios were calculated for associations between influenza hospitalization and PCV vaccination. Results: One hundred ninety-four cases and 342 controls were included in the study. In the 2009 to 2010 pandemic wave, the adjusted benefit in preventing hospitalization was 48% (95% confidence interval: 1 to 76) in fully vaccinated children compared with -79% (95% confidence interval: -341 to 27) in the 2010 to 2011 influenza season. Conclusions: The results obtained suggest that, in children <5 years of age, PCV vaccination reduced hospitalization during the 2009 to 2010 pandemic wave. By contrast, there was no observed benefit of vaccination in the 2010 to 2011 influenza season.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0891-3668</s0></fA01><fA02 i1="01"><s0>PIDJEV</s0></fA02><fA03 i2="1"><s0>Pediatr. infect. dis. j.</s0></fA03><fA05><s2>32</s2></fA05><fA06><s2>4</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Benefit of Conjugate Pneumococcal Vaccination in Preventing Influenza Hospitalization in Children: A Case-control Study</s1></fA08><fA11 i1="01" i2="1"><s1>DOMINGUEZ (Angela)</s1></fA11><fA11 i1="02" i2="1"><s1>CASTILLA (Jesús)</s1></fA11><fA11 i1="03" i2="1"><s1>GODOY (Pere)</s1></fA11><fA11 i1="04" i2="1"><s1>DELGADO-RODRIGUEZ (Miguel)</s1></fA11><fA11 i1="05" i2="1"><s1>SAEZ (Marc)</s1></fA11><fA11 i1="06" i2="1"><s1>SOLDEVILA (Núria)</s1></fA11><fA11 i1="07" i2="1"><s1>ASTRAY (Jenaro)</s1></fA11><fA11 i1="08" i2="1"><s1>MAYORAL (José María)</s1></fA11><fA11 i1="09" i2="1"><s1>MARTIN (Vicente)</s1></fA11><fA11 i1="10" i2="1"><s1>QUINTANA (José María)</s1></fA11><fA11 i1="11" i2="1"><s1>GONZALEZ-CANDELAS (Fernando)</s1></fA11><fA11 i1="12" i2="1"><s1>CARLOS GALAN (Juan)</s1></fA11><fA11 i1="13" i2="1"><s1>TAMAMES (Sonia)</s1></fA11><fA11 i1="14" i2="1"><s1>CASTRO ACOSTA (Ady)</s1></fA11><fA11 i1="15" i2="1"><s1>BARICOT (Maretva)</s1></fA11><fA11 i1="16" i2="1"><s1>GARIN (Olatz)</s1></fA11><fA11 i1="17" i2="1"><s1>JOSE GARCIA (Juan)</s1></fA11><fA11 i1="18" i2="1"><s1>MORAGA (Fernando)</s1></fA11><fA11 i1="19" i2="1"><s1>PUMAROLA (Tomás)</s1></fA11><fA14 i1="01"><s1>Department de Salut Publica, Universitat de Barcelona</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>1 aut.</sZ></fA14><fA14 i1="02"><s1>CIBER Epidemiologia y Salud Pública</s1><s2>Madrid</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></fA14><fA14 i1="03"><s1>Instituto de Salud Publica de Navarra</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>2 aut.</sZ></fA14><fA14 i1="04"><s1>Department de Salut, Generalitat de Catalunya</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>3 aut.</sZ></fA14><fA14 i1="05"><s1>Universidad de Jaen, Jaen; IIGRECS, Universitat de Girona</s1><s2>Girona</s2><s3>ESP</s3><sZ>4 aut.</sZ></fA14><fA14 i1="06"><s1>Area de Epidemiologia, Comunidad de Madrid</s1><s2>Madrid</s2><s3>ESP</s3><sZ>7 aut.</sZ></fA14><fA14 i1="07"><s1>Servicio de Vigilancia de Andalucia</s1><s3>ESP</s3><sZ>8 aut.</sZ></fA14><fA14 i1="08"><s1>Instituto de Biomedicina, Universidad de Leon</s1><s2>León</s2><s3>ESP</s3><sZ>9 aut.</sZ></fA14><fA14 i1="09"><s1>Unidad de Investigación, Hospital Galdakao-Usansolo</s1><s2>San Sebastian</s2><s3>ESP</s3><sZ>10 aut.</sZ></fA14><fA14 i1="10"><s1>Centro Superior de Investigación en Salud Pública, Universidad de Valencia</s1><s3>ESP</s3><sZ>11 aut.</sZ></fA14><fA14 i1="11"><s1>Hospital Universitario Ramón y Cajal</s1><s2>Madrid</s2><s3>ESP</s3><sZ>12 aut.</sZ></fA14><fA14 i1="12"><s1>Dirección General de Salud Pública e Investigación, Desarrollo e Innovación, Junta de Castilla y León</s1><s3>ESP</s3><sZ>13 aut.</sZ></fA14><fA14 i1="13"><s1>CIBER Enfermedades Respiratorias</s1><s3>ESP</s3><sZ>14 aut.</sZ></fA14><fA14 i1="14"><s1>Institut Municipal d' Investigació Mèdica</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>16 aut.</sZ></fA14><fA14 i1="15"><s1>Hospital Universitari San Joan de Déu</s1><s2>Esplugues</s2><s3>ESP</s3><sZ>17 aut.</sZ></fA14><fA14 i1="16"><s1>Hospital Universitari Vall d' Hebrón</s1><s3>ESP</s3><sZ>18 aut.</sZ></fA14><fA14 i1="17"><s1>Red Española de Investigación en Patologia Infecciosa</s1><s3>ESP</s3><sZ>19 aut.</sZ></fA14><fA17 i1="01" i2="1"><s1>CIBERESP Cases and Controls in Pandemic Influenza Working Group</s1><s3>ESP</s3></fA17><fA20><s1>330-334</s1></fA20><fA21><s1>2013</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>20356</s2><s5>354000503744960050</s5></fA43><fA44><s0>0000</s0><s1>© 2013 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>36 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>13-0152004</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>The Pediatric infectious disease journal</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>Background: The pneumococcal conjugate vaccine (PCV) might prevent hospitalizations in children because of the role of Streptococcus pneumoniae in the complications of influenza infection. We investigated the benefit of PCV vaccination in preventing influenza hospitalization in children <5 years of age during the 2009 to 2010 pandemic wave and the 2010 to 2011 influenza epidemic in Spain. Methods: A multicenter matched case-control study was undertaken in 27 hospitals from 7 Spanish regions between July 2009 and April 2011. A case was defined as a hospitalized patient between 6 months and 5 years of age with influenza virus infection confirmed by real-time reverse-transcription polymerase chain reaction. We selected 2 matched controls for each case from patients with unplanned hospital admission for reasons other than acute respiratory infection or influenza-like illness. Cases and controls were matched according to age, date of hospitalization and province of residence. Crude and adjusted odds ratios were calculated for associations between influenza hospitalization and PCV vaccination. Results: One hundred ninety-four cases and 342 controls were included in the study. In the 2009 to 2010 pandemic wave, the adjusted benefit in preventing hospitalization was 48% (95% confidence interval: 1 to 76) in fully vaccinated children compared with -79% (95% confidence interval: -341 to 27) in the 2010 to 2011 influenza season. Conclusions: The results obtained suggest that, in children <5 years of age, PCV vaccination reduced hospitalization during the 2009 to 2010 pandemic wave. By contrast, there was no observed benefit of vaccination in the 2010 to 2011 influenza season.</s0></fC01><fC02 i1="01" i2="X"><s0>002B05B02N</s0></fC02><fC02 i1="02" i2="X"><s0>002B05C02C</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Pneumococcie</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Pneumococcal infection</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Neumococia</s0><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Grippe A</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Influenza A</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Gripe A</s0><s5>02</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Immunoprophylaxie</s0><s5>04</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Immunoprophylaxis</s0><s5>04</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Inmunoprofilaxia</s0><s5>04</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Vaccination</s0><s5>07</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Vaccination</s0><s5>07</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Vacunación</s0><s5>07</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Prévention</s0><s5>08</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Prevention</s0><s5>08</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Prevención</s0><s5>08</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Hospitalisation</s0><s5>09</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Hospitalization</s0><s5>09</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Hospitalización</s0><s5>09</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Streptococcus pneumoniae</s0><s2>NS</s2><s5>10</s5></fC03><fC03 i1="07" i2="X" l="ENG"><s0>Streptococcus pneumoniae</s0><s2>NS</s2><s5>10</s5></fC03><fC03 i1="07" i2="X" l="SPA"><s0>Streptococcus pneumoniae</s0><s2>NS</s2><s5>10</s5></fC03><fC03 i1="08" i2="X" l="FRE"><s0>Enfant</s0><s5>11</s5></fC03><fC03 i1="08" i2="X" l="ENG"><s0>Child</s0><s5>11</s5></fC03><fC03 i1="08" i2="X" l="SPA"><s0>Niño</s0><s5>11</s5></fC03><fC03 i1="09" i2="X" l="FRE"><s0>Etude cas témoin</s0><s5>13</s5></fC03><fC03 i1="09" i2="X" l="ENG"><s0>Case control study</s0><s5>13</s5></fC03><fC03 i1="09" i2="X" l="SPA"><s0>Estudio caso control</s0><s5>13</s5></fC03><fC03 i1="10" i2="X" l="FRE"><s0>Vaccin associé</s0><s5>14</s5></fC03><fC03 i1="10" i2="X" l="ENG"><s0>Mixed vaccine</s0><s5>14</s5></fC03><fC03 i1="10" i2="X" l="SPA"><s0>Vacuna mixta</s0><s5>14</s5></fC03><fC03 i1="11" i2="X" l="FRE"><s0>Variation saisonnière</s0><s5>15</s5></fC03><fC03 i1="11" i2="X" l="ENG"><s0>Seasonal variation</s0><s5>15</s5></fC03><fC03 i1="11" i2="X" l="SPA"><s0>Variación estacional</s0><s5>15</s5></fC03><fC03 i1="12" i2="X" l="FRE"><s0>Pédiatrie</s0><s5>17</s5></fC03><fC03 i1="12" i2="X" l="ENG"><s0>Pediatrics</s0><s5>17</s5></fC03><fC03 i1="12" i2="X" l="SPA"><s0>Pediatría</s0><s5>17</s5></fC03><fC03 i1="13" i2="X" l="FRE"><s0>Pandémie</s0><s4>INC</s4><s5>86</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Streptococcie</s0></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Streptococcal infection</s0></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Estreptococia</s0></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Bactériose</s0></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Bacteriosis</s0></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Bacteriosis</s0></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Infection</s0></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Infection</s0></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Infección</s0></fC07><fC07 i1="04" i2="X" l="FRE"><s0>Virose</s0></fC07><fC07 i1="04" i2="X" l="ENG"><s0>Viral disease</s0></fC07><fC07 i1="04" i2="X" l="SPA"><s0>Virosis</s0></fC07><fC07 i1="05" i2="X" l="FRE"><s0>Streptococcaceae</s0><s2>NS</s2></fC07><fC07 i1="05" i2="X" l="ENG"><s0>Streptococcaceae</s0><s2>NS</s2></fC07><fC07 i1="05" i2="X" l="SPA"><s0>Streptococcaceae</s0><s2>NS</s2></fC07><fC07 i1="06" i2="X" l="FRE"><s0>Micrococcales</s0><s2>NS</s2></fC07><fC07 i1="06" i2="X" l="ENG"><s0>Micrococcales</s0><s2>NS</s2></fC07><fC07 i1="06" i2="X" l="SPA"><s0>Micrococcales</s0><s2>NS</s2></fC07><fC07 i1="07" i2="X" l="FRE"><s0>Bactérie</s0></fC07><fC07 i1="07" i2="X" l="ENG"><s0>Bacteria</s0></fC07><fC07 i1="07" i2="X" l="SPA"><s0>Bacteria</s0></fC07><fC07 i1="08" i2="X" l="FRE"><s0>Homme</s0></fC07><fC07 i1="08" i2="X" l="ENG"><s0>Human</s0></fC07><fC07 i1="08" i2="X" l="SPA"><s0>Hombre</s0></fC07><fC07 i1="09" i2="X" l="FRE"><s0>Epidémiologie</s0><s5>37</s5></fC07><fC07 i1="09" i2="X" l="ENG"><s0>Epidemiology</s0><s5>37</s5></fC07><fC07 i1="09" i2="X" l="SPA"><s0>Epidemiología</s0><s5>37</s5></fC07><fN21><s1>125</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard><server><NO>PASCAL 13-0152004 INIST</NO><ET>Benefit of Conjugate Pneumococcal Vaccination in Preventing Influenza Hospitalization in Children: A Case-control Study</ET><AU>DOMINGUEZ (Angela); CASTILLA (Jesús); GODOY (Pere); DELGADO-RODRIGUEZ (Miguel); SAEZ (Marc); SOLDEVILA (Núria); ASTRAY (Jenaro); MAYORAL (José María); MARTIN (Vicente); QUINTANA (José María); GONZALEZ-CANDELAS (Fernando); CARLOS GALAN (Juan); TAMAMES (Sonia); CASTRO ACOSTA (Ady); BARICOT (Maretva); GARIN (Olatz); JOSE GARCIA (Juan); MORAGA (Fernando); PUMAROLA (Tomás)</AU><AF>Department de Salut Publica, Universitat de Barcelona/Barcelona/Espagne (1 aut.); CIBER Epidemiologia y Salud Pública/Madrid/Espagne (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut., 9 aut., 10 aut., 11 aut., 12 aut., 15 aut., 16 aut.); Instituto de Salud Publica de Navarra/Pamplona/Espagne (2 aut.); Department de Salut, Generalitat de Catalunya/Barcelona/Espagne (3 aut.); Universidad de Jaen, Jaen; IIGRECS, Universitat de Girona/Girona/Espagne (4 aut.); Area de Epidemiologia, Comunidad de Madrid/Madrid/Espagne (7 aut.); Servicio de Vigilancia de Andalucia/Espagne (8 aut.); Instituto de Biomedicina, Universidad de Leon/León/Espagne (9 aut.); Unidad de Investigación, Hospital Galdakao-Usansolo/San Sebastian/Espagne (10 aut.); Centro Superior de Investigación en Salud Pública, Universidad de Valencia/Espagne (11 aut.); Hospital Universitario Ramón y Cajal/Madrid/Espagne (12 aut.); Dirección General de Salud Pública e Investigación, Desarrollo e Innovación, Junta de Castilla y León/Espagne (13 aut.); CIBER Enfermedades Respiratorias/Espagne (14 aut.); Institut Municipal d' Investigació Mèdica/Barcelona/Espagne (16 aut.); Hospital Universitari San Joan de Déu/Esplugues/Espagne (17 aut.); Hospital Universitari Vall d' Hebrón/Espagne (18 aut.); Red Española de Investigación en Patologia Infecciosa/Espagne (19 aut.)</AF><DT>Publication en série; Niveau analytique</DT><SO>The Pediatric infectious disease journal; ISSN 0891-3668; Coden PIDJEV; Etats-Unis; Da. 2013; Vol. 32; No. 4; Pp. 330-334; Bibl. 36 ref.</SO><LA>Anglais</LA><EA>Background: The pneumococcal conjugate vaccine (PCV) might prevent hospitalizations in children because of the role of Streptococcus pneumoniae in the complications of influenza infection. We investigated the benefit of PCV vaccination in preventing influenza hospitalization in children <5 years of age during the 2009 to 2010 pandemic wave and the 2010 to 2011 influenza epidemic in Spain. Methods: A multicenter matched case-control study was undertaken in 27 hospitals from 7 Spanish regions between July 2009 and April 2011. A case was defined as a hospitalized patient between 6 months and 5 years of age with influenza virus infection confirmed by real-time reverse-transcription polymerase chain reaction. We selected 2 matched controls for each case from patients with unplanned hospital admission for reasons other than acute respiratory infection or influenza-like illness. Cases and controls were matched according to age, date of hospitalization and province of residence. Crude and adjusted odds ratios were calculated for associations between influenza hospitalization and PCV vaccination. Results: One hundred ninety-four cases and 342 controls were included in the study. In the 2009 to 2010 pandemic wave, the adjusted benefit in preventing hospitalization was 48% (95% confidence interval: 1 to 76) in fully vaccinated children compared with -79% (95% confidence interval: -341 to 27) in the 2010 to 2011 influenza season. Conclusions: The results obtained suggest that, in children <5 years of age, PCV vaccination reduced hospitalization during the 2009 to 2010 pandemic wave. By contrast, there was no observed benefit of vaccination in the 2010 to 2011 influenza season.</EA><CC>002B05B02N; 002B05C02C</CC><FD>Pneumococcie; Grippe A; Immunoprophylaxie; Vaccination; Prévention; Hospitalisation; Streptococcus pneumoniae; Enfant; Etude cas témoin; Vaccin associé; Variation saisonnière; Pédiatrie; Pandémie</FD><FG>Streptococcie; Bactériose; Infection; Virose; Streptococcaceae; Micrococcales; Bactérie; Homme; Epidémiologie</FG><ED>Pneumococcal infection; Influenza A; Immunoprophylaxis; Vaccination; Prevention; Hospitalization; Streptococcus pneumoniae; Child; Case control study; Mixed vaccine; Seasonal variation; Pediatrics</ED><EG>Streptococcal infection; Bacteriosis; Infection; Viral disease; Streptococcaceae; Micrococcales; Bacteria; Human; Epidemiology</EG><SD>Neumococia; Gripe A; Inmunoprofilaxia; Vacunación; Prevención; Hospitalización; Streptococcus pneumoniae; Niño; Estudio caso control; Vacuna mixta; Variación estacional; Pediatría</SD><LO>INIST-20356.354000503744960050</LO><ID>13-0152004</ID></server></inist></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/PascalFrancis/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000313 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 000313 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= PandemieGrippaleV1
|flux= PascalFrancis
|étape= Corpus
|type= RBID
|clé= Pascal:13-0152004
|texte= Benefit of Conjugate Pneumococcal Vaccination in Preventing Influenza Hospitalization in Children: A Case-control Study
}}
| This area was generated with Dilib version V0.6.34. |  |