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Understanding the burden of influenza infection among adults in Canadian hospitals: A comparison of the 2009-2010 pandemic season with the prepandemic and postpandemic seasons

Identifieur interne : 000174 ( PascalFrancis/Corpus ); précédent : 000173; suivant : 000175

Understanding the burden of influenza infection among adults in Canadian hospitals: A comparison of the 2009-2010 pandemic season with the prepandemic and postpandemic seasons

Auteurs : Robyn Mitchell ; Geoffrey Taylor ; Allison Mcgeer ; Charles Frenette ; Kathryn N. Suh ; Alice Wong ; Kevin Katz ; Krista Wilkinson ; Barbara Amihod ; Denise Gravel

Source :

RBID : Pascal:14-0008710

Descripteurs français

English descriptors

Abstract

Background: The degree to which the 2009-2010 influenza pandemic season differed from previous and subsequent influenza seasons in Canadian hospitals has not yet been assessed. Methods: Surveillance for laboratory-confirmed influenza among adults in 51 Canadian Nosocomial Infection Surveillance Program hospitals was conducted between November 1, 2006, and May 31, 2011. Inpatient characteristics, treatment, and outcomes of influenza cases in the pandemic season (2009-2010) were compared with those in the prepandemic (2006-2007 to 2008-2009) and postpandemic (2010-2011) seasons. Results: The incidence of influenza infection was lower in the postpandemic season (1.59/1,000 admissions) compared with the prepandemic seasons (2.00/1,000 admissions; P < .001) and the pandemic season (1.80/1,000 admissions; P < .001). The proportion of cases classified as health care-associated was much smaller during the pandemic season (6.6%) than in either the prepandemic season (23.2%; P < .001) or the postpandemic season (23.6%; P < .001). Inpatients in the pandemic season were significantly younger compared with those in the prepandemic and postpandemic seasons (P < .001). Inpatients in the pandemic season were less likely to have been vaccinated (P < .001), but more likely to be treated with antiviral agents (P < .001), than inpatients in both the prepandemic and postpandemic seasons. Intensive care unit admission was greater during the pandemic season, but there were no significant differences in 30-day mortality among the seasons. Conclusions: Among adult inpatients, the pH1N1 pandemic season differed from seasonal influenza in terms of age, vaccination status, antiviral use, and intensive care unit admission, but not in terms of 30-day mortality.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A03   1    @0 Am. j. infect. control
A05       @2 41
A06       @2 11
A08 01  1  ENG  @1 Understanding the burden of influenza infection among adults in Canadian hospitals: A comparison of the 2009-2010 pandemic season with the prepandemic and postpandemic seasons
A11 01  1    @1 MITCHELL (Robyn)
A11 02  1    @1 TAYLOR (Geoffrey)
A11 03  1    @1 MCGEER (Allison)
A11 04  1    @1 FRENETTE (Charles)
A11 05  1    @1 SUH (Kathryn N.)
A11 06  1    @1 WONG (Alice)
A11 07  1    @1 KATZ (Kevin)
A11 08  1    @1 WILKINSON (Krista)
A11 09  1    @1 AMIHOD (Barbara)
A11 10  1    @1 GRAVEL (Denise)
A14 01      @1 Public Health Agency of Canada, Centre for Communicable Diseases and Infection Control @2 Ottawa, Ontario @3 CAN @Z 1 aut. @Z 8 aut. @Z 10 aut.
A14 02      @1 Department of Medicine, Division of Infectious Diseases, University of Alberta Hospital @2 Edmonton, Alberta @3 CAN @Z 2 aut.
A14 03      @1 Department of Microbiology, Mount Sinai Hospital @2 Toronto, Ontario @3 CAN @Z 3 aut.
A14 04      @1 Division of Infectious Diseases, Infection Control Service, McGill University Health Centre @2 Montreal, Quebec @3 CAN @Z 4 aut.
A14 05      @1 Department of Infection Prevention and Control, The Ottawa Hospital @2 Ottawa, Ontario @3 CAN @Z 5 aut.
A14 06      @1 Infection Prevention and Control Program, Royal University Hospital @2 Saskatoon, Saskatchewan @3 CAN @Z 6 aut.
A14 07      @1 Department of Infection Prevention and Control, North York General Hospital @2 Toronto, Ontario @3 CAN @Z 7 aut.
A14 08      @1 Department of Infection Prevention and Control, Jewish General Hospital @2 Montreal, Quebec @3 CAN @Z 9 aut.
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C01 01    ENG  @0 Background: The degree to which the 2009-2010 influenza pandemic season differed from previous and subsequent influenza seasons in Canadian hospitals has not yet been assessed. Methods: Surveillance for laboratory-confirmed influenza among adults in 51 Canadian Nosocomial Infection Surveillance Program hospitals was conducted between November 1, 2006, and May 31, 2011. Inpatient characteristics, treatment, and outcomes of influenza cases in the pandemic season (2009-2010) were compared with those in the prepandemic (2006-2007 to 2008-2009) and postpandemic (2010-2011) seasons. Results: The incidence of influenza infection was lower in the postpandemic season (1.59/1,000 admissions) compared with the prepandemic seasons (2.00/1,000 admissions; P < .001) and the pandemic season (1.80/1,000 admissions; P < .001). The proportion of cases classified as health care-associated was much smaller during the pandemic season (6.6%) than in either the prepandemic season (23.2%; P < .001) or the postpandemic season (23.6%; P < .001). Inpatients in the pandemic season were significantly younger compared with those in the prepandemic and postpandemic seasons (P < .001). Inpatients in the pandemic season were less likely to have been vaccinated (P < .001), but more likely to be treated with antiviral agents (P < .001), than inpatients in both the prepandemic and postpandemic seasons. Intensive care unit admission was greater during the pandemic season, but there were no significant differences in 30-day mortality among the seasons. Conclusions: Among adult inpatients, the pH1N1 pandemic season differed from seasonal influenza in terms of age, vaccination status, antiviral use, and intensive care unit admission, but not in terms of 30-day mortality.
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Format Inist (serveur)

NO : PASCAL 14-0008710 INIST
ET : Understanding the burden of influenza infection among adults in Canadian hospitals: A comparison of the 2009-2010 pandemic season with the prepandemic and postpandemic seasons
AU : MITCHELL (Robyn); TAYLOR (Geoffrey); MCGEER (Allison); FRENETTE (Charles); SUH (Kathryn N.); WONG (Alice); KATZ (Kevin); WILKINSON (Krista); AMIHOD (Barbara); GRAVEL (Denise)
AF : Public Health Agency of Canada, Centre for Communicable Diseases and Infection Control/Ottawa, Ontario/Canada (1 aut., 8 aut., 10 aut.); Department of Medicine, Division of Infectious Diseases, University of Alberta Hospital/Edmonton, Alberta/Canada (2 aut.); Department of Microbiology, Mount Sinai Hospital/Toronto, Ontario/Canada (3 aut.); Division of Infectious Diseases, Infection Control Service, McGill University Health Centre/Montreal, Quebec/Canada (4 aut.); Department of Infection Prevention and Control, The Ottawa Hospital/Ottawa, Ontario/Canada (5 aut.); Infection Prevention and Control Program, Royal University Hospital/Saskatoon, Saskatchewan/Canada (6 aut.); Department of Infection Prevention and Control, North York General Hospital/Toronto, Ontario/Canada (7 aut.); Department of Infection Prevention and Control, Jewish General Hospital/Montreal, Quebec/Canada (9 aut.)
DT : Publication en série; Niveau analytique
SO : American journal of infection control; ISSN 0196-6553; Etats-Unis; Da. 2013; Vol. 41; No. 11; Pp. 1032-1037; Bibl. 21 ref.
LA : Anglais
EA : Background: The degree to which the 2009-2010 influenza pandemic season differed from previous and subsequent influenza seasons in Canadian hospitals has not yet been assessed. Methods: Surveillance for laboratory-confirmed influenza among adults in 51 Canadian Nosocomial Infection Surveillance Program hospitals was conducted between November 1, 2006, and May 31, 2011. Inpatient characteristics, treatment, and outcomes of influenza cases in the pandemic season (2009-2010) were compared with those in the prepandemic (2006-2007 to 2008-2009) and postpandemic (2010-2011) seasons. Results: The incidence of influenza infection was lower in the postpandemic season (1.59/1,000 admissions) compared with the prepandemic seasons (2.00/1,000 admissions; P < .001) and the pandemic season (1.80/1,000 admissions; P < .001). The proportion of cases classified as health care-associated was much smaller during the pandemic season (6.6%) than in either the prepandemic season (23.2%; P < .001) or the postpandemic season (23.6%; P < .001). Inpatients in the pandemic season were significantly younger compared with those in the prepandemic and postpandemic seasons (P < .001). Inpatients in the pandemic season were less likely to have been vaccinated (P < .001), but more likely to be treated with antiviral agents (P < .001), than inpatients in both the prepandemic and postpandemic seasons. Intensive care unit admission was greater during the pandemic season, but there were no significant differences in 30-day mortality among the seasons. Conclusions: Among adult inpatients, the pH1N1 pandemic season differed from seasonal influenza in terms of age, vaccination status, antiviral use, and intensive care unit admission, but not in terms of 30-day mortality.
CC : 002B05A02; 002B05C02C; 002B05A03
FD : Grippe; Infection nosocomiale; Adulte; Canada; Hôpital; Etude comparative; Surveillance; Hospitalisation; Epidémiologie; Contrôle; Pandémie
FG : Virose; Infection; Homme; Amérique du Nord; Amérique; Prévention
ED : Influenza; Nosocomial infection; Adult; Canada; Hospital; Comparative study; Surveillance; Hospitalization; Epidemiology; Check
EG : Viral disease; Infection; Human; North America; America; Prevention
SD : Gripe; Infección nosocomial; Adulto; Canadá; Hospital; Estudio comparativo; Vigilancia; Hospitalización; Epidemiología; Control
LO : INIST-19097.354000507506040170
ID : 14-0008710

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Pascal:14-0008710

Le document en format XML

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<div type="abstract" xml:lang="en">Background: The degree to which the 2009-2010 influenza pandemic season differed from previous and subsequent influenza seasons in Canadian hospitals has not yet been assessed. Methods: Surveillance for laboratory-confirmed influenza among adults in 51 Canadian Nosocomial Infection Surveillance Program hospitals was conducted between November 1, 2006, and May 31, 2011. Inpatient characteristics, treatment, and outcomes of influenza cases in the pandemic season (2009-2010) were compared with those in the prepandemic (2006-2007 to 2008-2009) and postpandemic (2010-2011) seasons. Results: The incidence of influenza infection was lower in the postpandemic season (1.59/1,000 admissions) compared with the prepandemic seasons (2.00/1,000 admissions; P < .001) and the pandemic season (1.80/1,000 admissions; P < .001). The proportion of cases classified as health care-associated was much smaller during the pandemic season (6.6%) than in either the prepandemic season (23.2%; P < .001) or the postpandemic season (23.6%; P < .001). Inpatients in the pandemic season were significantly younger compared with those in the prepandemic and postpandemic seasons (P < .001). Inpatients in the pandemic season were less likely to have been vaccinated (P < .001), but more likely to be treated with antiviral agents (P < .001), than inpatients in both the prepandemic and postpandemic seasons. Intensive care unit admission was greater during the pandemic season, but there were no significant differences in 30-day mortality among the seasons. Conclusions: Among adult inpatients, the pH1N1 pandemic season differed from seasonal influenza in terms of age, vaccination status, antiviral use, and intensive care unit admission, but not in terms of 30-day mortality.</div>
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<ET>Understanding the burden of influenza infection among adults in Canadian hospitals: A comparison of the 2009-2010 pandemic season with the prepandemic and postpandemic seasons</ET>
<AU>MITCHELL (Robyn); TAYLOR (Geoffrey); MCGEER (Allison); FRENETTE (Charles); SUH (Kathryn N.); WONG (Alice); KATZ (Kevin); WILKINSON (Krista); AMIHOD (Barbara); GRAVEL (Denise)</AU>
<AF>Public Health Agency of Canada, Centre for Communicable Diseases and Infection Control/Ottawa, Ontario/Canada (1 aut., 8 aut., 10 aut.); Department of Medicine, Division of Infectious Diseases, University of Alberta Hospital/Edmonton, Alberta/Canada (2 aut.); Department of Microbiology, Mount Sinai Hospital/Toronto, Ontario/Canada (3 aut.); Division of Infectious Diseases, Infection Control Service, McGill University Health Centre/Montreal, Quebec/Canada (4 aut.); Department of Infection Prevention and Control, The Ottawa Hospital/Ottawa, Ontario/Canada (5 aut.); Infection Prevention and Control Program, Royal University Hospital/Saskatoon, Saskatchewan/Canada (6 aut.); Department of Infection Prevention and Control, North York General Hospital/Toronto, Ontario/Canada (7 aut.); Department of Infection Prevention and Control, Jewish General Hospital/Montreal, Quebec/Canada (9 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>American journal of infection control; ISSN 0196-6553; Etats-Unis; Da. 2013; Vol. 41; No. 11; Pp. 1032-1037; Bibl. 21 ref.</SO>
<LA>Anglais</LA>
<EA>Background: The degree to which the 2009-2010 influenza pandemic season differed from previous and subsequent influenza seasons in Canadian hospitals has not yet been assessed. Methods: Surveillance for laboratory-confirmed influenza among adults in 51 Canadian Nosocomial Infection Surveillance Program hospitals was conducted between November 1, 2006, and May 31, 2011. Inpatient characteristics, treatment, and outcomes of influenza cases in the pandemic season (2009-2010) were compared with those in the prepandemic (2006-2007 to 2008-2009) and postpandemic (2010-2011) seasons. Results: The incidence of influenza infection was lower in the postpandemic season (1.59/1,000 admissions) compared with the prepandemic seasons (2.00/1,000 admissions; P < .001) and the pandemic season (1.80/1,000 admissions; P < .001). The proportion of cases classified as health care-associated was much smaller during the pandemic season (6.6%) than in either the prepandemic season (23.2%; P < .001) or the postpandemic season (23.6%; P < .001). Inpatients in the pandemic season were significantly younger compared with those in the prepandemic and postpandemic seasons (P < .001). Inpatients in the pandemic season were less likely to have been vaccinated (P < .001), but more likely to be treated with antiviral agents (P < .001), than inpatients in both the prepandemic and postpandemic seasons. Intensive care unit admission was greater during the pandemic season, but there were no significant differences in 30-day mortality among the seasons. Conclusions: Among adult inpatients, the pH1N1 pandemic season differed from seasonal influenza in terms of age, vaccination status, antiviral use, and intensive care unit admission, but not in terms of 30-day mortality.</EA>
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<ED>Influenza; Nosocomial infection; Adult; Canada; Hospital; Comparative study; Surveillance; Hospitalization; Epidemiology; Check</ED>
<EG>Viral disease; Infection; Human; North America; America; Prevention</EG>
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