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Cleaning of filtering facepiece respirators contaminated with mucin and Staphylococcus aureus

Identifieur interne : 000134 ( PascalFrancis/Corpus ); précédent : 000133; suivant : 000135

Cleaning of filtering facepiece respirators contaminated with mucin and Staphylococcus aureus

Auteurs : Brian K. Heimbuch ; Kimberly Kinney ; April E. Lumley ; Delbert A. Harnish ; Michael Bergman ; Joseph D. Wander

Source :

RBID : Pascal:14-0092839

Descripteurs français

English descriptors

Abstract

Background: Decontamination, cleaning, and reuse of filtering facepiece respirators (FFRs) has been proposed to mitigate an acute FFR shortage during a public health emergency. Our study evaluates the ability of commercially available wipe products to clean FFRs contaminated with either infectious or noninfectious aerosols. Methods: Three models of surgical N95 FFRs were contaminated with aerosols of mucin or viable Staphylococcus aureus then cleaned with hypochlorite, benzalkonium chloride, or nonantimicrobial wipes. After cleaning, FFRs were separated into components (nose pad, fabrics, and perforated strip), and contaminants were extracted and quantified. Filtration performance was assessed for cleaned FFRs. Results: Mucin removal was <1 log for all wipe products on all components. Inert wipes achieved ∼ 1-log attenuation in viable S aureus on fabrics from all FFR models-removal was less effective from nose pads and perforated edges. Both antimicrobial wipes achieved 3-5-log attenuation on most components, with smaller reductions on nose pads and greater reductions on perforated strips. Particle penetration following cleaning yielded mean values <5%. The highest penetrations were observed in FFRs cleaned with benzalkonium chloride wipes. Conclusions: FFRs can be disinfected using antimicrobial wipe products, but not effectively cleaned with the wipes evaluated in this study. This study provides informative data for the development of better FFRs and applicable cleaning products.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0196-6553
A03   1    @0 Am. j. infect. control
A05       @2 42
A06       @2 3
A08 01  1  ENG  @1 Cleaning of filtering facepiece respirators contaminated with mucin and Staphylococcus aureus
A11 01  1    @1 HEIMBUCH (Brian K.)
A11 02  1    @1 KINNEY (Kimberly)
A11 03  1    @1 LUMLEY (April E.)
A11 04  1    @1 HARNISH (Delbert A.)
A11 05  1    @1 BERGMAN (Michael)
A11 06  1    @1 WANDER (Joseph D.)
A14 01      @1 Applied Research Associates @2 Panama City, FL @3 USA @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut.
A14 02      @1 National Institute for Occupational Safety and Health @2 Pittsburgh, PA @3 USA @Z 5 aut.
A14 03      @1 Air Force Research Laboratory @2 Tyndall Air Force Base, FL @3 USA @Z 6 aut.
A20       @1 265-270
A21       @1 2014
A23 01      @0 ENG
A43 01      @1 INIST @2 19097 @5 354000506157160090
A44       @0 0000 @1 © 2014 INIST-CNRS. All rights reserved.
A45       @0 22 ref.
A47 01  1    @0 14-0092839
A60       @1 P
A61       @0 A
A64 01  1    @0 American journal of infection control
A66 01      @0 USA
C01 01    ENG  @0 Background: Decontamination, cleaning, and reuse of filtering facepiece respirators (FFRs) has been proposed to mitigate an acute FFR shortage during a public health emergency. Our study evaluates the ability of commercially available wipe products to clean FFRs contaminated with either infectious or noninfectious aerosols. Methods: Three models of surgical N95 FFRs were contaminated with aerosols of mucin or viable Staphylococcus aureus then cleaned with hypochlorite, benzalkonium chloride, or nonantimicrobial wipes. After cleaning, FFRs were separated into components (nose pad, fabrics, and perforated strip), and contaminants were extracted and quantified. Filtration performance was assessed for cleaned FFRs. Results: Mucin removal was <1 log for all wipe products on all components. Inert wipes achieved ∼ 1-log attenuation in viable S aureus on fabrics from all FFR models-removal was less effective from nose pads and perforated edges. Both antimicrobial wipes achieved 3-5-log attenuation on most components, with smaller reductions on nose pads and greater reductions on perforated strips. Particle penetration following cleaning yielded mean values <5%. The highest penetrations were observed in FFRs cleaned with benzalkonium chloride wipes. Conclusions: FFRs can be disinfected using antimicrobial wipe products, but not effectively cleaned with the wipes evaluated in this study. This study provides informative data for the development of better FFRs and applicable cleaning products.
C02 01  X    @0 002B05A02
C02 02  X    @0 002B05B02N
C02 03  X    @0 002B05C02C
C03 01  X  FRE  @0 Staphylococcie @5 01
C03 01  X  ENG  @0 Staphylococcal infection @5 01
C03 01  X  SPA  @0 Estafilococia @5 01
C03 02  X  FRE  @0 Grippe @5 02
C03 02  X  ENG  @0 Influenza @5 02
C03 02  X  SPA  @0 Gripe @5 02
C03 03  X  FRE  @0 Nettoyage @5 07
C03 03  X  ENG  @0 Cleaning @5 07
C03 03  X  SPA  @0 Limpieza @5 07
C03 04  X  FRE  @0 Contamination @5 08
C03 04  X  ENG  @0 Contamination @5 08
C03 04  X  SPA  @0 Contaminación @5 08
C03 05  X  FRE  @0 Mucine @5 09
C03 05  X  ENG  @0 Mucin @5 09
C03 05  X  SPA  @0 Mucina @5 09
C03 06  X  FRE  @0 Staphylococcus aureus @2 NS @5 10
C03 06  X  ENG  @0 Staphylococcus aureus @2 NS @5 10
C03 06  X  SPA  @0 Staphylococcus aureus @2 NS @5 10
C03 07  X  FRE  @0 Aérosol @5 13
C03 07  X  ENG  @0 Aerosols @5 13
C03 07  X  SPA  @0 Aerosol @5 13
C03 08  X  FRE  @0 Décontamination @5 14
C03 08  X  ENG  @0 Decontamination @5 14
C03 08  X  SPA  @0 Descontaminación @5 14
C03 09  X  FRE  @0 Salive @5 15
C03 09  X  ENG  @0 Saliva @5 15
C03 09  X  SPA  @0 Saliva @5 15
C03 10  X  FRE  @0 Contrôle @5 30
C03 10  X  ENG  @0 Check @5 30
C03 10  X  SPA  @0 Control @5 30
C03 11  X  FRE  @0 Pandémie @4 INC @5 86
C07 01  X  FRE  @0 Bactériose
C07 01  X  ENG  @0 Bacteriosis
C07 01  X  SPA  @0 Bacteriosis
C07 02  X  FRE  @0 Infection
C07 02  X  ENG  @0 Infection
C07 02  X  SPA  @0 Infección
C07 03  X  FRE  @0 Virose
C07 03  X  ENG  @0 Viral disease
C07 03  X  SPA  @0 Virosis
C07 04  X  FRE  @0 Micrococcaceae @2 NS
C07 04  X  ENG  @0 Micrococcaceae @2 NS
C07 04  X  SPA  @0 Micrococcaceae @2 NS
C07 05  X  FRE  @0 Micrococcales @2 NS
C07 05  X  ENG  @0 Micrococcales @2 NS
C07 05  X  SPA  @0 Micrococcales @2 NS
C07 06  X  FRE  @0 Bactérie
C07 06  X  ENG  @0 Bacteria
C07 06  X  SPA  @0 Bacteria
C07 07  X  FRE  @0 Prévention @5 37
C07 07  X  ENG  @0 Prevention @5 37
C07 07  X  SPA  @0 Prevención @5 37
N21       @1 125
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 14-0092839 INIST
ET : Cleaning of filtering facepiece respirators contaminated with mucin and Staphylococcus aureus
AU : HEIMBUCH (Brian K.); KINNEY (Kimberly); LUMLEY (April E.); HARNISH (Delbert A.); BERGMAN (Michael); WANDER (Joseph D.)
AF : Applied Research Associates/Panama City, FL/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut.); National Institute for Occupational Safety and Health/Pittsburgh, PA/Etats-Unis (5 aut.); Air Force Research Laboratory/Tyndall Air Force Base, FL/Etats-Unis (6 aut.)
DT : Publication en série; Niveau analytique
SO : American journal of infection control; ISSN 0196-6553; Etats-Unis; Da. 2014; Vol. 42; No. 3; Pp. 265-270; Bibl. 22 ref.
LA : Anglais
EA : Background: Decontamination, cleaning, and reuse of filtering facepiece respirators (FFRs) has been proposed to mitigate an acute FFR shortage during a public health emergency. Our study evaluates the ability of commercially available wipe products to clean FFRs contaminated with either infectious or noninfectious aerosols. Methods: Three models of surgical N95 FFRs were contaminated with aerosols of mucin or viable Staphylococcus aureus then cleaned with hypochlorite, benzalkonium chloride, or nonantimicrobial wipes. After cleaning, FFRs were separated into components (nose pad, fabrics, and perforated strip), and contaminants were extracted and quantified. Filtration performance was assessed for cleaned FFRs. Results: Mucin removal was <1 log for all wipe products on all components. Inert wipes achieved ∼ 1-log attenuation in viable S aureus on fabrics from all FFR models-removal was less effective from nose pads and perforated edges. Both antimicrobial wipes achieved 3-5-log attenuation on most components, with smaller reductions on nose pads and greater reductions on perforated strips. Particle penetration following cleaning yielded mean values <5%. The highest penetrations were observed in FFRs cleaned with benzalkonium chloride wipes. Conclusions: FFRs can be disinfected using antimicrobial wipe products, but not effectively cleaned with the wipes evaluated in this study. This study provides informative data for the development of better FFRs and applicable cleaning products.
CC : 002B05A02; 002B05B02N; 002B05C02C
FD : Staphylococcie; Grippe; Nettoyage; Contamination; Mucine; Staphylococcus aureus; Aérosol; Décontamination; Salive; Contrôle; Pandémie
FG : Bactériose; Infection; Virose; Micrococcaceae; Micrococcales; Bactérie; Prévention
ED : Staphylococcal infection; Influenza; Cleaning; Contamination; Mucin; Staphylococcus aureus; Aerosols; Decontamination; Saliva; Check
EG : Bacteriosis; Infection; Viral disease; Micrococcaceae; Micrococcales; Bacteria; Prevention
SD : Estafilococia; Gripe; Limpieza; Contaminación; Mucina; Staphylococcus aureus; Aerosol; Descontaminación; Saliva; Control
LO : INIST-19097.354000506157160090
ID : 14-0092839

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Pascal:14-0092839

Le document en format XML

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<div type="abstract" xml:lang="en">Background: Decontamination, cleaning, and reuse of filtering facepiece respirators (FFRs) has been proposed to mitigate an acute FFR shortage during a public health emergency. Our study evaluates the ability of commercially available wipe products to clean FFRs contaminated with either infectious or noninfectious aerosols. Methods: Three models of surgical N95 FFRs were contaminated with aerosols of mucin or viable Staphylococcus aureus then cleaned with hypochlorite, benzalkonium chloride, or nonantimicrobial wipes. After cleaning, FFRs were separated into components (nose pad, fabrics, and perforated strip), and contaminants were extracted and quantified. Filtration performance was assessed for cleaned FFRs. Results: Mucin removal was <1 log for all wipe products on all components. Inert wipes achieved ∼ 1-log attenuation in viable S aureus on fabrics from all FFR models-removal was less effective from nose pads and perforated edges. Both antimicrobial wipes achieved 3-5-log attenuation on most components, with smaller reductions on nose pads and greater reductions on perforated strips. Particle penetration following cleaning yielded mean values <5%. The highest penetrations were observed in FFRs cleaned with benzalkonium chloride wipes. Conclusions: FFRs can be disinfected using antimicrobial wipe products, but not effectively cleaned with the wipes evaluated in this study. This study provides informative data for the development of better FFRs and applicable cleaning products.</div>
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<s5>01</s5>
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<fC03 i1="01" i2="X" l="SPA">
<s0>Estafilococia</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Grippe</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Influenza</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Gripe</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Nettoyage</s0>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Cleaning</s0>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Limpieza</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Contamination</s0>
<s5>08</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Contamination</s0>
<s5>08</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Contaminación</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Mucine</s0>
<s5>09</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Mucin</s0>
<s5>09</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Mucina</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Staphylococcus aureus</s0>
<s2>NS</s2>
<s5>10</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Staphylococcus aureus</s0>
<s2>NS</s2>
<s5>10</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Staphylococcus aureus</s0>
<s2>NS</s2>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Aérosol</s0>
<s5>13</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Aerosols</s0>
<s5>13</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Aerosol</s0>
<s5>13</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Décontamination</s0>
<s5>14</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Decontamination</s0>
<s5>14</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Descontaminación</s0>
<s5>14</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Salive</s0>
<s5>15</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Saliva</s0>
<s5>15</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Saliva</s0>
<s5>15</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE">
<s0>Contrôle</s0>
<s5>30</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG">
<s0>Check</s0>
<s5>30</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA">
<s0>Control</s0>
<s5>30</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE">
<s0>Pandémie</s0>
<s4>INC</s4>
<s5>86</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Bactériose</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Bacteriosis</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Bacteriosis</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Infection</s0>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Infection</s0>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Infección</s0>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Virose</s0>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Viral disease</s0>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Virosis</s0>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Micrococcaceae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Micrococcaceae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Micrococcaceae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Micrococcales</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Micrococcales</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Micrococcales</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Bactérie</s0>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Bacteria</s0>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Bacteria</s0>
</fC07>
<fC07 i1="07" i2="X" l="FRE">
<s0>Prévention</s0>
<s5>37</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG">
<s0>Prevention</s0>
<s5>37</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA">
<s0>Prevención</s0>
<s5>37</s5>
</fC07>
<fN21>
<s1>125</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
<server>
<NO>PASCAL 14-0092839 INIST</NO>
<ET>Cleaning of filtering facepiece respirators contaminated with mucin and Staphylococcus aureus</ET>
<AU>HEIMBUCH (Brian K.); KINNEY (Kimberly); LUMLEY (April E.); HARNISH (Delbert A.); BERGMAN (Michael); WANDER (Joseph D.)</AU>
<AF>Applied Research Associates/Panama City, FL/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut.); National Institute for Occupational Safety and Health/Pittsburgh, PA/Etats-Unis (5 aut.); Air Force Research Laboratory/Tyndall Air Force Base, FL/Etats-Unis (6 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>American journal of infection control; ISSN 0196-6553; Etats-Unis; Da. 2014; Vol. 42; No. 3; Pp. 265-270; Bibl. 22 ref.</SO>
<LA>Anglais</LA>
<EA>Background: Decontamination, cleaning, and reuse of filtering facepiece respirators (FFRs) has been proposed to mitigate an acute FFR shortage during a public health emergency. Our study evaluates the ability of commercially available wipe products to clean FFRs contaminated with either infectious or noninfectious aerosols. Methods: Three models of surgical N95 FFRs were contaminated with aerosols of mucin or viable Staphylococcus aureus then cleaned with hypochlorite, benzalkonium chloride, or nonantimicrobial wipes. After cleaning, FFRs were separated into components (nose pad, fabrics, and perforated strip), and contaminants were extracted and quantified. Filtration performance was assessed for cleaned FFRs. Results: Mucin removal was <1 log for all wipe products on all components. Inert wipes achieved ∼ 1-log attenuation in viable S aureus on fabrics from all FFR models-removal was less effective from nose pads and perforated edges. Both antimicrobial wipes achieved 3-5-log attenuation on most components, with smaller reductions on nose pads and greater reductions on perforated strips. Particle penetration following cleaning yielded mean values <5%. The highest penetrations were observed in FFRs cleaned with benzalkonium chloride wipes. Conclusions: FFRs can be disinfected using antimicrobial wipe products, but not effectively cleaned with the wipes evaluated in this study. This study provides informative data for the development of better FFRs and applicable cleaning products.</EA>
<CC>002B05A02; 002B05B02N; 002B05C02C</CC>
<FD>Staphylococcie; Grippe; Nettoyage; Contamination; Mucine; Staphylococcus aureus; Aérosol; Décontamination; Salive; Contrôle; Pandémie</FD>
<FG>Bactériose; Infection; Virose; Micrococcaceae; Micrococcales; Bactérie; Prévention</FG>
<ED>Staphylococcal infection; Influenza; Cleaning; Contamination; Mucin; Staphylococcus aureus; Aerosols; Decontamination; Saliva; Check</ED>
<EG>Bacteriosis; Infection; Viral disease; Micrococcaceae; Micrococcales; Bacteria; Prevention</EG>
<SD>Estafilococia; Gripe; Limpieza; Contaminación; Mucina; Staphylococcus aureus; Aerosol; Descontaminación; Saliva; Control</SD>
<LO>INIST-19097.354000506157160090</LO>
<ID>14-0092839</ID>
</server>
</inist>
</record>

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