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Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission

Identifieur interne : 000020 ( PascalFrancis/Corpus ); précédent : 000019; suivant : 000021

Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission

Auteurs : J. Rebolledo ; D. Igoe ; J. O'Donnell ; L. Domegan ; M. Boland ; B. Freyne ; A. Mcnamara ; E. Molloy ; M. Callaghan ; A. Ryan ; D. O'Flanagan

Source :

RBID : Pascal:14-0277467

Descripteurs français

English descriptors

Abstract

Influenza causes significant morbidity and mortality in children. This study's objectives were to describe influenza A(H1N1)pdm09 during the pandemic, to compare it with circulating influenza in 2010/2011, and to identify risk factors for severe influenza defined as requiring admission to a paediatric intensive care unit (PICU). Children hospitalized with influenza during the pandemic were older, and more likely to have received antiviral therapy than children hospitalized during the 2010/2011 season. In 2010/2011, only one child admitted to a PICU with underlying medical conditions had been vaccinated. The risk of severe illness in the pandemic was higher in females and those with underlying conditions. In 2010/2011, infection with influenza A(H1N1)pdm09 compared to other influenza viruses was a significant risk factor for severe disease. An incremental relationship was found between the number of underlying conditions and PICU admission. These findings highlight the importance of improving low vaccination uptake and increasing the use of antivirals in vulnerable children.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0950-2688
A02 01      @0 EPINEU
A03   1    @0 Epidemiol. infect.
A05       @2 142
A06       @2 9
A08 01  1  ENG  @1 Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission
A11 01  1    @1 REBOLLEDO (J.)
A11 02  1    @1 IGOE (D.)
A11 03  1    @1 O'DONNELL (J.)
A11 04  1    @1 DOMEGAN (L.)
A11 05  1    @1 BOLAND (M.)
A11 06  1    @1 FREYNE (B.)
A11 07  1    @1 MCNAMARA (A.)
A11 08  1    @1 MOLLOY (E.)
A11 09  1    @1 CALLAGHAN (M.)
A11 10  1    @1 RYAN (A.)
A11 11  1    @1 O'FLANAGAN (D.)
A14 01      @1 Health Protection Surveillance Centre, Health Service Executive @2 Dublin @3 IRL @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 11 aut.
A14 02      @1 European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC) @2 Stockholm @3 SWE @Z 1 aut.
A14 03      @1 Department of Public Health, Health Service Executive Dublin @3 IRL @Z 5 aut.
A14 04      @1 National Maternity Hospital, Holies Street @2 Dublin @3 IRL @Z 6 aut. @Z 8 aut.
A14 05      @1 Department of Public Health, Health Service Executive Tullamore @3 IRL @Z 7 aut.
A14 06      @1 Our Lady's Children's Hospital @2 Crumlin, Dublin @3 IRL @Z 8 aut.
A14 07      @1 Department of Anaesthesia and Intensive Care Medicine, Our Lady's Children's Hospital @2 Crumlin, Dublin @3 IRL @Z 9 aut.
A14 08      @1 Department of Public Health, Health Service Executive Sligo @3 IRL @Z 10 aut.
A20       @1 1826-1835
A21       @1 2014
A23 01      @0 ENG
A43 01      @1 INIST @2 6056 @5 354000150354970050
A44       @0 0000 @1 © 2014 INIST-CNRS. All rights reserved.
A45       @0 37 ref.
A47 01  1    @0 14-0277467
A60       @1 P
A61       @0 A
A64 01  1    @0 Epidemiology and infection
A66 01      @0 GBR
C01 01    ENG  @0 Influenza causes significant morbidity and mortality in children. This study's objectives were to describe influenza A(H1N1)pdm09 during the pandemic, to compare it with circulating influenza in 2010/2011, and to identify risk factors for severe influenza defined as requiring admission to a paediatric intensive care unit (PICU). Children hospitalized with influenza during the pandemic were older, and more likely to have received antiviral therapy than children hospitalized during the 2010/2011 season. In 2010/2011, only one child admitted to a PICU with underlying medical conditions had been vaccinated. The risk of severe illness in the pandemic was higher in females and those with underlying conditions. In 2010/2011, infection with influenza A(H1N1)pdm09 compared to other influenza viruses was a significant risk factor for severe disease. An incremental relationship was found between the number of underlying conditions and PICU admission. These findings highlight the importance of improving low vaccination uptake and increasing the use of antivirals in vulnerable children.
C02 01  X    @0 002A05
C03 01  X  FRE  @0 Enfant @5 05
C03 01  X  ENG  @0 Child @5 05
C03 01  X  SPA  @0 Niño @5 05
C03 02  X  FRE  @0 Irlande @2 NG @5 06
C03 02  X  ENG  @0 Ireland @2 NG @5 06
C03 02  X  SPA  @0 Irlanda @2 NG @5 06
C03 03  X  FRE  @0 Facteur risque @5 07
C03 03  X  ENG  @0 Risk factor @5 07
C03 03  X  SPA  @0 Factor riesgo @5 07
C03 04  X  FRE  @0 Epidémiologie @5 08
C03 04  X  ENG  @0 Epidemiology @5 08
C03 04  X  SPA  @0 Epidemiología @5 08
C03 05  X  FRE  @0 Grippe @5 14
C03 05  X  ENG  @0 Influenza @5 14
C03 05  X  SPA  @0 Gripe @5 14
C07 01  X  FRE  @0 Homme
C07 01  X  ENG  @0 Human
C07 01  X  SPA  @0 Hombre
C07 02  X  FRE  @0 Europe @2 NG
C07 02  X  ENG  @0 Europe @2 NG
C07 02  X  SPA  @0 Europa @2 NG
C07 03  X  FRE  @0 Europe Ouest @2 NG @5 13
C07 03  X  ENG  @0 Western Europe @2 NG @5 13
C07 03  X  SPA  @0 Europa del Oeste @2 NG @5 13
C07 04  X  FRE  @0 Virose
C07 04  X  ENG  @0 Viral disease
C07 04  X  SPA  @0 Virosis
C07 05  X  FRE  @0 Infection
C07 05  X  ENG  @0 Infection
C07 05  X  SPA  @0 Infección
N21       @1 349
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 14-0277467 INIST
ET : Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission
AU : REBOLLEDO (J.); IGOE (D.); O'DONNELL (J.); DOMEGAN (L.); BOLAND (M.); FREYNE (B.); MCNAMARA (A.); MOLLOY (E.); CALLAGHAN (M.); RYAN (A.); O'FLANAGAN (D.)
AF : Health Protection Surveillance Centre, Health Service Executive/Dublin/Irlande (1 aut., 2 aut., 3 aut., 4 aut., 11 aut.); European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC)/Stockholm/Suède (1 aut.); Department of Public Health, Health Service Executive Dublin/Irlande (5 aut.); National Maternity Hospital, Holies Street/Dublin/Irlande (6 aut., 8 aut.); Department of Public Health, Health Service Executive Tullamore/Irlande (7 aut.); Our Lady's Children's Hospital/Crumlin, Dublin/Irlande (8 aut.); Department of Anaesthesia and Intensive Care Medicine, Our Lady's Children's Hospital/Crumlin, Dublin/Irlande (9 aut.); Department of Public Health, Health Service Executive Sligo/Irlande (10 aut.)
DT : Publication en série; Niveau analytique
SO : Epidemiology and infection; ISSN 0950-2688; Coden EPINEU; Royaume-Uni; Da. 2014; Vol. 142; No. 9; Pp. 1826-1835; Bibl. 37 ref.
LA : Anglais
EA : Influenza causes significant morbidity and mortality in children. This study's objectives were to describe influenza A(H1N1)pdm09 during the pandemic, to compare it with circulating influenza in 2010/2011, and to identify risk factors for severe influenza defined as requiring admission to a paediatric intensive care unit (PICU). Children hospitalized with influenza during the pandemic were older, and more likely to have received antiviral therapy than children hospitalized during the 2010/2011 season. In 2010/2011, only one child admitted to a PICU with underlying medical conditions had been vaccinated. The risk of severe illness in the pandemic was higher in females and those with underlying conditions. In 2010/2011, infection with influenza A(H1N1)pdm09 compared to other influenza viruses was a significant risk factor for severe disease. An incremental relationship was found between the number of underlying conditions and PICU admission. These findings highlight the importance of improving low vaccination uptake and increasing the use of antivirals in vulnerable children.
CC : 002A05
FD : Enfant; Irlande; Facteur risque; Epidémiologie; Grippe
FG : Homme; Europe; Europe Ouest; Virose; Infection
ED : Child; Ireland; Risk factor; Epidemiology; Influenza
EG : Human; Europe; Western Europe; Viral disease; Infection
SD : Niño; Irlanda; Factor riesgo; Epidemiología; Gripe
LO : INIST-6056.354000150354970050
ID : 14-0277467

Links to Exploration step

Pascal:14-0277467

Le document en format XML

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<div type="abstract" xml:lang="en">Influenza causes significant morbidity and mortality in children. This study's objectives were to describe influenza A(H1N1)pdm09 during the pandemic, to compare it with circulating influenza in 2010/2011, and to identify risk factors for severe influenza defined as requiring admission to a paediatric intensive care unit (PICU). Children hospitalized with influenza during the pandemic were older, and more likely to have received antiviral therapy than children hospitalized during the 2010/2011 season. In 2010/2011, only one child admitted to a PICU with underlying medical conditions had been vaccinated. The risk of severe illness in the pandemic was higher in females and those with underlying conditions. In 2010/2011, infection with influenza A(H1N1)pdm09 compared to other influenza viruses was a significant risk factor for severe disease. An incremental relationship was found between the number of underlying conditions and PICU admission. These findings highlight the importance of improving low vaccination uptake and increasing the use of antivirals in vulnerable children.</div>
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<s0>Influenza causes significant morbidity and mortality in children. This study's objectives were to describe influenza A(H1N1)pdm09 during the pandemic, to compare it with circulating influenza in 2010/2011, and to identify risk factors for severe influenza defined as requiring admission to a paediatric intensive care unit (PICU). Children hospitalized with influenza during the pandemic were older, and more likely to have received antiviral therapy than children hospitalized during the 2010/2011 season. In 2010/2011, only one child admitted to a PICU with underlying medical conditions had been vaccinated. The risk of severe illness in the pandemic was higher in females and those with underlying conditions. In 2010/2011, infection with influenza A(H1N1)pdm09 compared to other influenza viruses was a significant risk factor for severe disease. An incremental relationship was found between the number of underlying conditions and PICU admission. These findings highlight the importance of improving low vaccination uptake and increasing the use of antivirals in vulnerable children.</s0>
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<s5>05</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG">
<s0>Child</s0>
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<s5>07</s5>
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<s5>08</s5>
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<s5>14</s5>
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<s0>Europe</s0>
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<fC07 i1="02" i2="X" l="SPA">
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<s2>NG</s2>
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<s2>NG</s2>
<s5>13</s5>
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<s5>13</s5>
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<fC07 i1="04" i2="X" l="ENG">
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<ET>Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission</ET>
<AU>REBOLLEDO (J.); IGOE (D.); O'DONNELL (J.); DOMEGAN (L.); BOLAND (M.); FREYNE (B.); MCNAMARA (A.); MOLLOY (E.); CALLAGHAN (M.); RYAN (A.); O'FLANAGAN (D.)</AU>
<AF>Health Protection Surveillance Centre, Health Service Executive/Dublin/Irlande (1 aut., 2 aut., 3 aut., 4 aut., 11 aut.); European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC)/Stockholm/Suède (1 aut.); Department of Public Health, Health Service Executive Dublin/Irlande (5 aut.); National Maternity Hospital, Holies Street/Dublin/Irlande (6 aut., 8 aut.); Department of Public Health, Health Service Executive Tullamore/Irlande (7 aut.); Our Lady's Children's Hospital/Crumlin, Dublin/Irlande (8 aut.); Department of Anaesthesia and Intensive Care Medicine, Our Lady's Children's Hospital/Crumlin, Dublin/Irlande (9 aut.); Department of Public Health, Health Service Executive Sligo/Irlande (10 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Epidemiology and infection; ISSN 0950-2688; Coden EPINEU; Royaume-Uni; Da. 2014; Vol. 142; No. 9; Pp. 1826-1835; Bibl. 37 ref.</SO>
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<EA>Influenza causes significant morbidity and mortality in children. This study's objectives were to describe influenza A(H1N1)pdm09 during the pandemic, to compare it with circulating influenza in 2010/2011, and to identify risk factors for severe influenza defined as requiring admission to a paediatric intensive care unit (PICU). Children hospitalized with influenza during the pandemic were older, and more likely to have received antiviral therapy than children hospitalized during the 2010/2011 season. In 2010/2011, only one child admitted to a PICU with underlying medical conditions had been vaccinated. The risk of severe illness in the pandemic was higher in females and those with underlying conditions. In 2010/2011, infection with influenza A(H1N1)pdm09 compared to other influenza viruses was a significant risk factor for severe disease. An incremental relationship was found between the number of underlying conditions and PICU admission. These findings highlight the importance of improving low vaccination uptake and increasing the use of antivirals in vulnerable children.</EA>
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