Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission
Identifieur interne : 000020 ( PascalFrancis/Corpus ); précédent : 000019; suivant : 000021Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission
Auteurs : J. Rebolledo ; D. Igoe ; J. O'Donnell ; L. Domegan ; M. Boland ; B. Freyne ; A. Mcnamara ; E. Molloy ; M. Callaghan ; A. Ryan ; D. O'FlanaganSource :
- Epidemiology and infection [ 0950-2688 ] ; 2014.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Influenza causes significant morbidity and mortality in children. This study's objectives were to describe influenza A(H1N1)pdm09 during the pandemic, to compare it with circulating influenza in 2010/2011, and to identify risk factors for severe influenza defined as requiring admission to a paediatric intensive care unit (PICU). Children hospitalized with influenza during the pandemic were older, and more likely to have received antiviral therapy than children hospitalized during the 2010/2011 season. In 2010/2011, only one child admitted to a PICU with underlying medical conditions had been vaccinated. The risk of severe illness in the pandemic was higher in females and those with underlying conditions. In 2010/2011, infection with influenza A(H1N1)pdm09 compared to other influenza viruses was a significant risk factor for severe disease. An incremental relationship was found between the number of underlying conditions and PICU admission. These findings highlight the importance of improving low vaccination uptake and increasing the use of antivirals in vulnerable children.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 14-0277467 INIST |
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ET : | Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission |
AU : | REBOLLEDO (J.); IGOE (D.); O'DONNELL (J.); DOMEGAN (L.); BOLAND (M.); FREYNE (B.); MCNAMARA (A.); MOLLOY (E.); CALLAGHAN (M.); RYAN (A.); O'FLANAGAN (D.) |
AF : | Health Protection Surveillance Centre, Health Service Executive/Dublin/Irlande (1 aut., 2 aut., 3 aut., 4 aut., 11 aut.); European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC)/Stockholm/Suède (1 aut.); Department of Public Health, Health Service Executive Dublin/Irlande (5 aut.); National Maternity Hospital, Holies Street/Dublin/Irlande (6 aut., 8 aut.); Department of Public Health, Health Service Executive Tullamore/Irlande (7 aut.); Our Lady's Children's Hospital/Crumlin, Dublin/Irlande (8 aut.); Department of Anaesthesia and Intensive Care Medicine, Our Lady's Children's Hospital/Crumlin, Dublin/Irlande (9 aut.); Department of Public Health, Health Service Executive Sligo/Irlande (10 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Epidemiology and infection; ISSN 0950-2688; Coden EPINEU; Royaume-Uni; Da. 2014; Vol. 142; No. 9; Pp. 1826-1835; Bibl. 37 ref. |
LA : | Anglais |
EA : | Influenza causes significant morbidity and mortality in children. This study's objectives were to describe influenza A(H1N1)pdm09 during the pandemic, to compare it with circulating influenza in 2010/2011, and to identify risk factors for severe influenza defined as requiring admission to a paediatric intensive care unit (PICU). Children hospitalized with influenza during the pandemic were older, and more likely to have received antiviral therapy than children hospitalized during the 2010/2011 season. In 2010/2011, only one child admitted to a PICU with underlying medical conditions had been vaccinated. The risk of severe illness in the pandemic was higher in females and those with underlying conditions. In 2010/2011, infection with influenza A(H1N1)pdm09 compared to other influenza viruses was a significant risk factor for severe disease. An incremental relationship was found between the number of underlying conditions and PICU admission. These findings highlight the importance of improving low vaccination uptake and increasing the use of antivirals in vulnerable children. |
CC : | 002A05 |
FD : | Enfant; Irlande; Facteur risque; Epidémiologie; Grippe |
FG : | Homme; Europe; Europe Ouest; Virose; Infection |
ED : | Child; Ireland; Risk factor; Epidemiology; Influenza |
EG : | Human; Europe; Western Europe; Viral disease; Infection |
SD : | Niño; Irlanda; Factor riesgo; Epidemiología; Gripe |
LO : | INIST-6056.354000150354970050 |
ID : | 14-0277467 |
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Pascal:14-0277467Le document en format XML
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<front><div type="abstract" xml:lang="en">Influenza causes significant morbidity and mortality in children. This study's objectives were to describe influenza A(H1N1)pdm09 during the pandemic, to compare it with circulating influenza in 2010/2011, and to identify risk factors for severe influenza defined as requiring admission to a paediatric intensive care unit (PICU). Children hospitalized with influenza during the pandemic were older, and more likely to have received antiviral therapy than children hospitalized during the 2010/2011 season. In 2010/2011, only one child admitted to a PICU with underlying medical conditions had been vaccinated. The risk of severe illness in the pandemic was higher in females and those with underlying conditions. In 2010/2011, infection with influenza A(H1N1)pdm09 compared to other influenza viruses was a significant risk factor for severe disease. An incremental relationship was found between the number of underlying conditions and PICU admission. These findings highlight the importance of improving low vaccination uptake and increasing the use of antivirals in vulnerable children.</div>
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<s5>06</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Facteur risque</s0>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Risk factor</s0>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Factor riesgo</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Epidémiologie</s0>
<s5>08</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Epidemiology</s0>
<s5>08</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Epidemiología</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Grippe</s0>
<s5>14</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Influenza</s0>
<s5>14</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Gripe</s0>
<s5>14</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Homme</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Human</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Hombre</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Europe</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Europe</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Europa</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Europe Ouest</s0>
<s2>NG</s2>
<s5>13</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Western Europe</s0>
<s2>NG</s2>
<s5>13</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Europa del Oeste</s0>
<s2>NG</s2>
<s5>13</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Virose</s0>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Viral disease</s0>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Virosis</s0>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Infection</s0>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Infection</s0>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Infección</s0>
</fC07>
<fN21><s1>349</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
<server><NO>PASCAL 14-0277467 INIST</NO>
<ET>Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission</ET>
<AU>REBOLLEDO (J.); IGOE (D.); O'DONNELL (J.); DOMEGAN (L.); BOLAND (M.); FREYNE (B.); MCNAMARA (A.); MOLLOY (E.); CALLAGHAN (M.); RYAN (A.); O'FLANAGAN (D.)</AU>
<AF>Health Protection Surveillance Centre, Health Service Executive/Dublin/Irlande (1 aut., 2 aut., 3 aut., 4 aut., 11 aut.); European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC)/Stockholm/Suède (1 aut.); Department of Public Health, Health Service Executive Dublin/Irlande (5 aut.); National Maternity Hospital, Holies Street/Dublin/Irlande (6 aut., 8 aut.); Department of Public Health, Health Service Executive Tullamore/Irlande (7 aut.); Our Lady's Children's Hospital/Crumlin, Dublin/Irlande (8 aut.); Department of Anaesthesia and Intensive Care Medicine, Our Lady's Children's Hospital/Crumlin, Dublin/Irlande (9 aut.); Department of Public Health, Health Service Executive Sligo/Irlande (10 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Epidemiology and infection; ISSN 0950-2688; Coden EPINEU; Royaume-Uni; Da. 2014; Vol. 142; No. 9; Pp. 1826-1835; Bibl. 37 ref.</SO>
<LA>Anglais</LA>
<EA>Influenza causes significant morbidity and mortality in children. This study's objectives were to describe influenza A(H1N1)pdm09 during the pandemic, to compare it with circulating influenza in 2010/2011, and to identify risk factors for severe influenza defined as requiring admission to a paediatric intensive care unit (PICU). Children hospitalized with influenza during the pandemic were older, and more likely to have received antiviral therapy than children hospitalized during the 2010/2011 season. In 2010/2011, only one child admitted to a PICU with underlying medical conditions had been vaccinated. The risk of severe illness in the pandemic was higher in females and those with underlying conditions. In 2010/2011, infection with influenza A(H1N1)pdm09 compared to other influenza viruses was a significant risk factor for severe disease. An incremental relationship was found between the number of underlying conditions and PICU admission. These findings highlight the importance of improving low vaccination uptake and increasing the use of antivirals in vulnerable children.</EA>
<CC>002A05</CC>
<FD>Enfant; Irlande; Facteur risque; Epidémiologie; Grippe</FD>
<FG>Homme; Europe; Europe Ouest; Virose; Infection</FG>
<ED>Child; Ireland; Risk factor; Epidemiology; Influenza</ED>
<EG>Human; Europe; Western Europe; Viral disease; Infection</EG>
<SD>Niño; Irlanda; Factor riesgo; Epidemiología; Gripe</SD>
<LO>INIST-6056.354000150354970050</LO>
<ID>14-0277467</ID>
</server>
</inist>
</record>
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