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Antigenic and genomic characterization of human influenza A and B viruses circulating in Argentina after the introduction of influenza A(H1N1)pdm09

Identifieur interne : 000005 ( PascalFrancis/Corpus ); précédent : 000004; suivant : 000006

Antigenic and genomic characterization of human influenza A and B viruses circulating in Argentina after the introduction of influenza A(H1N1)pdm09

Auteurs : Mara L. Russo ; Andrea V. Pontoriero ; Estefania Benedetti ; Andrea Czech ; Martin Avaro ; Natalia Periolo ; Ana M. Campos ; Vilma L. Savy ; Elsa G. Baumeister

Source :

RBID : Pascal:15-0021923

Descripteurs français

English descriptors

Abstract

This study was conducted as part of the Argentinean Influenza and other Respiratory Viruses Surveillance Network, in the context of the Global Influenza Surveillance carried out by the World Health Organization (WHO). The objective was to study the activity and the antigenic and genomic characteristics of circulating viruses for three consecutive seasons (2010, 2011 and 2012) in order to investigate the emergence of influenza viral variants. During the study period, influenza virus circulation was detected from January to December. Influenza A and B, and all current subtypes of human influenza viruses, were present each year. Throughout the 2010 post-pandemic season, influenza A(H1N1)pdm09, unexpectedly, almost disappeared. The haemagglutinin (HA) of the A(H1N1)pdm09 viruses studied were segregated in a different genetic group to those identified during the 2009 pandemic, although they were still antigenically closely related to the vaccine strain A/California/07/2009. Influenza A(H3N2) viruses were the predominant strains circulating during the 2011 season, accounting for nearly 76% of influenza viruses identified. That year, all HA sequences of the A(H3N2) viruses tested fell into the A/ Victoria/208/2009 genetic clade, but remained antigenically related to A/Perth/16/2009 (reference vaccine recommended for this three-year period). A(H3N2) viruses isolated in 2012 were antigenically closely related to A/Victoria/361/2011, recommended by the WHO as the H3 component for the 2013 Southern Hemisphere formulation. B viruses belonging to the B/Victoria lineage circulated in 2010. A mixed circulation of viral variants of both B/Victoria and B/Yamagata lineages was detected in 2012, with the former being predominant. A(H1N1)pdm09 viruses remained antigenically closely related to the vaccine virus A/California/7/2009; A(H3N2) viruses continually evolved into new antigenic clusters and both B lineages, B/Victoria/2/87-like and B/ Yamagata/16/88-like viruses, were observed during the study period. The virological surveillance showed that the majority of the circulating strains during the study period were antigenically related to the corresponding Southern Hemisphere vaccine strains except for the 2012 A(H3N2) viruses.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A08 01  1  ENG  @1 Antigenic and genomic characterization of human influenza A and B viruses circulating in Argentina after the introduction of influenza A(H1N1)pdm09
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A11 02  1    @1 PONTORIERO (Andrea V.)
A11 03  1    @1 BENEDETTI (Estefania)
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A11 05  1    @1 AVARO (Martin)
A11 06  1    @1 PERIOLO (Natalia)
A11 07  1    @1 CAMPOS (Ana M.)
A11 08  1    @1 SAVY (Vilma L.)
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A14 01      @1 National Influenza Centre PAHO/WHO, Servicio Virosis Respiratorias, Departamento Virologia, Instituto Nacional de Enfermedades Infecciosas, ANLIS 'Carlos G. Malbran' @2 Buenos Aires @3 ARG @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut. @Z 7 aut. @Z 8 aut. @Z 9 aut.
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C01 01    ENG  @0 This study was conducted as part of the Argentinean Influenza and other Respiratory Viruses Surveillance Network, in the context of the Global Influenza Surveillance carried out by the World Health Organization (WHO). The objective was to study the activity and the antigenic and genomic characteristics of circulating viruses for three consecutive seasons (2010, 2011 and 2012) in order to investigate the emergence of influenza viral variants. During the study period, influenza virus circulation was detected from January to December. Influenza A and B, and all current subtypes of human influenza viruses, were present each year. Throughout the 2010 post-pandemic season, influenza A(H1N1)pdm09, unexpectedly, almost disappeared. The haemagglutinin (HA) of the A(H1N1)pdm09 viruses studied were segregated in a different genetic group to those identified during the 2009 pandemic, although they were still antigenically closely related to the vaccine strain A/California/07/2009. Influenza A(H3N2) viruses were the predominant strains circulating during the 2011 season, accounting for nearly 76% of influenza viruses identified. That year, all HA sequences of the A(H3N2) viruses tested fell into the A/ Victoria/208/2009 genetic clade, but remained antigenically related to A/Perth/16/2009 (reference vaccine recommended for this three-year period). A(H3N2) viruses isolated in 2012 were antigenically closely related to A/Victoria/361/2011, recommended by the WHO as the H3 component for the 2013 Southern Hemisphere formulation. B viruses belonging to the B/Victoria lineage circulated in 2010. A mixed circulation of viral variants of both B/Victoria and B/Yamagata lineages was detected in 2012, with the former being predominant. A(H1N1)pdm09 viruses remained antigenically closely related to the vaccine virus A/California/7/2009; A(H3N2) viruses continually evolved into new antigenic clusters and both B lineages, B/Victoria/2/87-like and B/ Yamagata/16/88-like viruses, were observed during the study period. The virological surveillance showed that the majority of the circulating strains during the study period were antigenically related to the corresponding Southern Hemisphere vaccine strains except for the 2012 A(H3N2) viruses.
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Format Inist (serveur)

NO : PASCAL 15-0021923 INIST
ET : Antigenic and genomic characterization of human influenza A and B viruses circulating in Argentina after the introduction of influenza A(H1N1)pdm09
AU : RUSSO (Mara L.); PONTORIERO (Andrea V.); BENEDETTI (Estefania); CZECH (Andrea); AVARO (Martin); PERIOLO (Natalia); CAMPOS (Ana M.); SAVY (Vilma L.); BAUMEISTER (Elsa G.)
AF : National Influenza Centre PAHO/WHO, Servicio Virosis Respiratorias, Departamento Virologia, Instituto Nacional de Enfermedades Infecciosas, ANLIS 'Carlos G. Malbran'/Buenos Aires/Argentine (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut., 8 aut., 9 aut.)
DT : Publication en série; Niveau analytique
SO : Journal of medical microbiology; ISSN 0022-2615; Coden JMMIAV; Royaume-Uni; Da. 2014; Vol. 63; No. 12; Pp. 1626-1637; Bibl. 1 p.1/4
LA : Anglais
EA : This study was conducted as part of the Argentinean Influenza and other Respiratory Viruses Surveillance Network, in the context of the Global Influenza Surveillance carried out by the World Health Organization (WHO). The objective was to study the activity and the antigenic and genomic characteristics of circulating viruses for three consecutive seasons (2010, 2011 and 2012) in order to investigate the emergence of influenza viral variants. During the study period, influenza virus circulation was detected from January to December. Influenza A and B, and all current subtypes of human influenza viruses, were present each year. Throughout the 2010 post-pandemic season, influenza A(H1N1)pdm09, unexpectedly, almost disappeared. The haemagglutinin (HA) of the A(H1N1)pdm09 viruses studied were segregated in a different genetic group to those identified during the 2009 pandemic, although they were still antigenically closely related to the vaccine strain A/California/07/2009. Influenza A(H3N2) viruses were the predominant strains circulating during the 2011 season, accounting for nearly 76% of influenza viruses identified. That year, all HA sequences of the A(H3N2) viruses tested fell into the A/ Victoria/208/2009 genetic clade, but remained antigenically related to A/Perth/16/2009 (reference vaccine recommended for this three-year period). A(H3N2) viruses isolated in 2012 were antigenically closely related to A/Victoria/361/2011, recommended by the WHO as the H3 component for the 2013 Southern Hemisphere formulation. B viruses belonging to the B/Victoria lineage circulated in 2010. A mixed circulation of viral variants of both B/Victoria and B/Yamagata lineages was detected in 2012, with the former being predominant. A(H1N1)pdm09 viruses remained antigenically closely related to the vaccine virus A/California/7/2009; A(H3N2) viruses continually evolved into new antigenic clusters and both B lineages, B/Victoria/2/87-like and B/ Yamagata/16/88-like viruses, were observed during the study period. The virological surveillance showed that the majority of the circulating strains during the study period were antigenically related to the corresponding Southern Hemisphere vaccine strains except for the 2012 A(H3N2) viruses.
CC : 002A05C10; 002B05
FD : Homme; Virus grippal A; Génomique; Argentine; Grippe A
FG : Influenzavirus A; Orthomyxoviridae; Virus; Amérique du Sud; Amérique; Virose; Infection
ED : Human; Influenza A virus; Genomics; Argentina; Influenza A
EG : Influenzavirus A; Orthomyxoviridae; Virus; South America; America; Viral disease; Infection
SD : Hombre; Influenza A virus; Genómica; Argentina; Gripe A
LO : INIST-988B.354000503593070080
ID : 15-0021923

Links to Exploration step

Pascal:15-0021923

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<ET>Antigenic and genomic characterization of human influenza A and B viruses circulating in Argentina after the introduction of influenza A(H1N1)pdm09</ET>
<AU>RUSSO (Mara L.); PONTORIERO (Andrea V.); BENEDETTI (Estefania); CZECH (Andrea); AVARO (Martin); PERIOLO (Natalia); CAMPOS (Ana M.); SAVY (Vilma L.); BAUMEISTER (Elsa G.)</AU>
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