Serveur d'exploration sur les pandémies grippales

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Viral Infections of the Lung

Identifieur interne : 002243 ( Ncbi/Merge ); précédent : 002242; suivant : 002244

Viral Infections of the Lung

Auteurs :

Source :

RBID : PMC:7121437

Abstract

The lungs are among the most vulnerable to microbial assault of all organs in the body. From a contemporary vantage, lower respiratory tract infections are the greatest cause of infection-related mortality in the United States, and rank seventh among all causes of deaths in the United States.2,3 From a global and historic perspective, the scope and scale of lower respiratory tract infection is greater than any other infectious syndrome, and viral pneumonias have proven to be some of the most lethal and dramatic of human diseases. The 1918–1919 influenza pandemic, perhaps the most devastating infectious disease pandemic in recorded history, resulted in an estimated 40 million deaths worldwide, including 700,000 deaths in the U.S.4 The global outbreak of severe acute respiratory syndrome (SARS) during 2003, although considerably smaller in scale, resulted in 8098 cases and 774 deaths5 and is a dramatic contemporary example of the ability of viral pneumonias to rapidly disseminate and cause severe disease in human populations.


Url:
DOI: 10.1007/978-0-387-68792-6_11
PubMed: NONE
PubMed Central: 7121437

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PMC:7121437

Le document en format XML

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<p>The lungs are among the most vulnerable to microbial assault of all organs in the body. From a contemporary vantage, lower respiratory tract infections are the greatest cause of infection-related mortality in the United States, and rank seventh among all causes of deaths in the United States.
<xref ref-type="bibr" rid="CR2">2</xref>
,
<xref ref-type="bibr" rid="CR3">3</xref>
From a global and historic perspective, the scope and scale of lower respiratory tract infection is greater than any other infectious syndrome, and viral pneumonias have proven to be some of the most lethal and dramatic of human diseases. The 1918–1919 influenza pandemic, perhaps the most devastating infectious disease pandemic in recorded history, resulted in an estimated 40 million deaths worldwide, including 700,000 deaths in the U.S.
<xref ref-type="bibr" rid="CR4">4</xref>
The global outbreak of severe acute respiratory syndrome (SARS) during 2003, although considerably smaller in scale, resulted in 8098 cases and 774 deaths
<xref ref-type="bibr" rid="CR5">5</xref>
and is a dramatic contemporary example of the ability of viral pneumonias to rapidly disseminate and cause severe disease in human populations.</p>
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<pmc article-type="chapter-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">978-0-387-68792-6</journal-id>
<journal-id journal-id-type="doi">10.1007/978-0-387-68792-6</journal-id>
<journal-id journal-id-type="nlm-ta">Dail and Hammar’s Pulmonary Pathology</journal-id>
<journal-title-group>
<journal-title>Dail and Hammar’s Pulmonary Pathology</journal-title>
<journal-subtitle>Volume I: Nonneoplastic Lung Disease</journal-subtitle>
</journal-title-group>
<isbn publication-format="print">978-0-387-98395-0</isbn>
<isbn publication-format="electronic">978-0-387-68792-6</isbn>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmc">7121437</article-id>
<article-id pub-id-type="publisher-id">11</article-id>
<article-id pub-id-type="doi">10.1007/978-0-387-68792-6_11</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Viral Infections of the Lung</article-title>
</title-group>
<contrib-group content-type="book editors">
<contrib contrib-type="editor">
<name>
<surname>Tomashefski</surname>
<given-names>Joseph F.</given-names>
<suffix>Jr.</suffix>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="Aff1">1</xref>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="editor">
<name>
<surname>Cagle</surname>
<given-names>Philip T.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="Aff3">3</xref>
<xref ref-type="aff" rid="Aff4">4</xref>
</contrib>
<contrib contrib-type="editor">
<name>
<surname>Farver</surname>
<given-names>Carol F.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="Aff5">5</xref>
</contrib>
<contrib contrib-type="editor">
<name>
<surname>Fraire</surname>
<given-names>Armando E.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="Aff6">6</xref>
</contrib>
<aff id="Aff1">
<label>1</label>
<institution-wrap>
<institution-id institution-id-type="GRID">grid.67105.35</institution-id>
<institution-id institution-id-type="ISNI">0000000121643847</institution-id>
<institution>Department of Pathology,</institution>
<institution>Case Western Reserve University School of Medicine,</institution>
</institution-wrap>
Cleveland, OH USA</aff>
<aff id="Aff2">
<label>2</label>
<institution-wrap>
<institution-id institution-id-type="GRID">grid.411931.f</institution-id>
<institution-id institution-id-type="ISNI">0000000100354528</institution-id>
<institution>Department of Pathology,</institution>
<institution>MetroHealth Medical Center,</institution>
</institution-wrap>
Cleveland, OH USA</aff>
<aff id="Aff3">
<label>3</label>
<institution-wrap>
<institution-id institution-id-type="GRID">grid.5386.8</institution-id>
<institution-id institution-id-type="ISNI">000000041936877X</institution-id>
<institution>Department of Pathology,</institution>
<institution>Weill Medical College of Cornell University,</institution>
</institution-wrap>
New York, NY</aff>
<aff id="Aff4">
<label>4</label>
<institution-wrap>
<institution-id institution-id-type="GRID">grid.63368.38</institution-id>
<institution-id institution-id-type="ISNI">0000000404450041</institution-id>
<institution>Pulmonary Pathology, Department of Pathology,</institution>
<institution>The Methodist Hospital,</institution>
</institution-wrap>
Houston, TX USA</aff>
<aff id="Aff5">
<label>5</label>
<institution-wrap>
<institution-id institution-id-type="GRID">grid.239578.2</institution-id>
<institution-id institution-id-type="ISNI">0000000106754725</institution-id>
<institution>Pulmonary Pathology, Department of Anatomic Pathology,</institution>
<institution>The Cleveland Clinic Foundation,</institution>
</institution-wrap>
Cleveland, OH USA</aff>
<aff id="Aff6">
<label>6</label>
<institution-wrap>
<institution-id institution-id-type="GRID">grid.168645.8</institution-id>
<institution-id institution-id-type="ISNI">0000000107420364</institution-id>
<institution>Department of Pathology,</institution>
<institution>University of Massachusetts Medical School,</institution>
</institution-wrap>
Worcester, MA USA</aff>
</contrib-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Zaki</surname>
<given-names>Sherif R.</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="Aff7">7</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Paddock</surname>
<given-names>Christopher D.</given-names>
</name>
<degrees>MD, MS, MPHTM</degrees>
<xref ref-type="aff" rid="Aff8">8</xref>
</contrib>
<aff id="Aff7">
<label>7</label>
<institution-wrap>
<institution-id institution-id-type="GRID">grid.416738.f</institution-id>
<institution-id institution-id-type="ISNI">0000000121630069</institution-id>
<institution>Infectious Disease Pathology Activity, Department of Infectious Disease Pathology Activity,</institution>
<institution>Centers for Disease Control and Prevention,</institution>
</institution-wrap>
Atlanta, GA 30333 USA</aff>
<aff id="Aff8">
<label>8</label>
<institution-wrap>
<institution-id institution-id-type="GRID">grid.416738.f</institution-id>
<institution-id institution-id-type="ISNI">0000000121630069</institution-id>
<institution>Department of Infectious Disease Pathology Activity,</institution>
<institution>Centers for Disease Control and Prevention,</institution>
</institution-wrap>
Atlanta, GA 30333 USA</aff>
</contrib-group>
<pub-date pub-type="ppub">
<year>2008</year>
</pub-date>
<fpage>426</fpage>
<lpage>475</lpage>
<permissions>
<copyright-statement>© Springer Science+Business Media, LLC 2008</copyright-statement>
<license>
<license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p>
</license>
</permissions>
<abstract id="Abs1">
<p>The lungs are among the most vulnerable to microbial assault of all organs in the body. From a contemporary vantage, lower respiratory tract infections are the greatest cause of infection-related mortality in the United States, and rank seventh among all causes of deaths in the United States.
<xref ref-type="bibr" rid="CR2">2</xref>
,
<xref ref-type="bibr" rid="CR3">3</xref>
From a global and historic perspective, the scope and scale of lower respiratory tract infection is greater than any other infectious syndrome, and viral pneumonias have proven to be some of the most lethal and dramatic of human diseases. The 1918–1919 influenza pandemic, perhaps the most devastating infectious disease pandemic in recorded history, resulted in an estimated 40 million deaths worldwide, including 700,000 deaths in the U.S.
<xref ref-type="bibr" rid="CR4">4</xref>
The global outbreak of severe acute respiratory syndrome (SARS) during 2003, although considerably smaller in scale, resulted in 8098 cases and 774 deaths
<xref ref-type="bibr" rid="CR5">5</xref>
and is a dramatic contemporary example of the ability of viral pneumonias to rapidly disseminate and cause severe disease in human populations.</p>
</abstract>
<kwd-group xml:lang="en">
<title>Keywords</title>
<kwd>Respiratory Syncytial Virus</kwd>
<kwd>Severe Acute Respiratory Syndrome</kwd>
<kwd>Measle Virus</kwd>
<kwd>Hemorrhagic Fever</kwd>
<kwd>Hemorrhagic Fever With Renal Syndrome</kwd>
</kwd-group>
<custom-meta-group>
<custom-meta>
<meta-name>issue-copyright-statement</meta-name>
<meta-value>© Springer-Verlag New York 2008</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
<affiliations>
<list></list>
<tree></tree>
</affiliations>
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