PandemieGrippaleV1, Ncbi, Merge, bibRecord, 001F61

Meeting report narcolepsy and pandemic influenza vaccination: What we know and what we need to know before the next pandemic? A report from the 2nd IABS meeting.

Identifieur interne : 001F61 ( Ncbi/Merge ); précédent : 001F60; suivant : 001F62

Meeting report narcolepsy and pandemic influenza vaccination: What we know and what we need to know before the next pandemic? A report from the 2nd IABS meeting.

Auteurs : Kathryn Edwards [États-Unis] ; Germaine Hanquet [Belgique] ; Steve Black [États-Unis] ; Emmanuel Mignot [États-Unis] ; Christopher Jankosky [États-Unis] ; Tom Shimabukuro [États-Unis] ; Elizabeth Miller [Royaume-Uni] ; Hanna Nohynek [Finlande] ; Pieter Neels [Suisse]

Source :

Biologicals : journal of the International Association of Biological Standardization [ 1095-8320 ] ; 2019.

RBID : pubmed:31130313

Descripteurs français

KwdFr :
- Congrès comme sujet, Disciplines des sciences biologiques, Femelle, Grippe humaine (), Grippe humaine (immunologie), Grippe humaine (épidémiologie), Humains, Mâle, Narcolepsie (), Narcolepsie (immunologie), Narcolepsie (épidémiologie), Pandémies, Sociétés savantes, Sous-type H1N1 du virus de la grippe A (immunologie), Vaccination, Vaccins antigrippaux (administration et posologie), Vaccins antigrippaux (effets indésirables).
MESH :
- administration et posologie : Vaccins antigrippaux.
- effets indésirables : Vaccins antigrippaux.
- immunologie : Grippe humaine, Narcolepsie, Sous-type H1N1 du virus de la grippe A.
- épidémiologie : Grippe humaine, Narcolepsie.
- Congrès comme sujet, Disciplines des sciences biologiques, Femelle, Grippe humaine, Humains, Mâle, Narcolepsie, Pandémies, Sociétés savantes, Vaccination.

English descriptors

KwdEn :
- Biological Science Disciplines, Congresses as Topic, Female, Humans, Influenza A Virus, H1N1 Subtype (immunology), Influenza Vaccines (administration & dosage), Influenza Vaccines (adverse effects), Influenza, Human (epidemiology), Influenza, Human (immunology), Influenza, Human (prevention & control), Male, Narcolepsy (chemically induced), Narcolepsy (epidemiology), Narcolepsy (immunology), Pandemics, Societies, Scientific, Vaccination.
MESH :
- chemical , administration & dosage : Influenza Vaccines.
- chemical , adverse effects : Influenza Vaccines.
- chemically induced : Narcolepsy.
- epidemiology : Influenza, Human, Narcolepsy.
- immunology : Influenza A Virus, H1N1 Subtype, Influenza, Human, Narcolepsy.
- prevention & control : Influenza, Human.
- Biological Science Disciplines, Congresses as Topic, Female, Humans, Male, Pandemics, Societies, Scientific, Vaccination.

Abstract

A group of scientific and public health experts and key stakeholders convened to discuss the state of knowledge on the relationship between adjuvanted monovalent inactivated 2009 influenza A H1N1 vaccines used during the 2009 influenza pandemic and narcolepsy. There was consensus that an increased risk of narcolepsy was consistently observed after Pandemrix (AS03-adjuvanted) vaccine, but similar associations following Arepanrix (AS03-adjuvanted) or Focetria (MF59-adjuvanted) vaccines were not observed. Whether the differences are due to vaccine composition or other factors such as the timing of large-scale vaccination programs relative to H1N1pdm09 wild-type virus circulation in different geographic regions is not clear. The limitations of retrospective observational methodologies could also be contributing to some of the differences across studies. More basic and epidemiologic research is needed to further elucidate the association between adjuvanted influenza vaccine and narcolepsy and its mechanism and to inform planning and preparation for vaccination programs in advance of the next influenza pandemic.

DOI: 10.1016/j.biologicals.2019.05.005
PubMed: 31130313

Links toward previous steps (curation, corpus...)

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pubmed:31130313

Le document en format XML

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<front><div type="abstract" xml:lang="en">A group of scientific and public health experts and key stakeholders convened to discuss the state of knowledge on the relationship between adjuvanted monovalent inactivated 2009 influenza A H1N1 vaccines used during the 2009 influenza pandemic and narcolepsy. There was consensus that an increased risk of narcolepsy was consistently observed after Pandemrix (AS03-adjuvanted) vaccine, but similar associations following Arepanrix (AS03-adjuvanted) or Focetria (MF59-adjuvanted) vaccines were not observed. Whether the differences are due to vaccine composition or other factors such as the timing of large-scale vaccination programs relative to H1N1pdm09 wild-type virus circulation in different geographic regions is not clear. The limitations of retrospective observational methodologies could also be contributing to some of the differences across studies. More basic and epidemiologic research is needed to further elucidate the association between adjuvanted influenza vaccine and narcolepsy and its mechanism and to inform planning and preparation for vaccination programs in advance of the next influenza pandemic.</div>
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<Abstract><AbstractText>A group of scientific and public health experts and key stakeholders convened to discuss the state of knowledge on the relationship between adjuvanted monovalent inactivated 2009 influenza A H1N1 vaccines used during the 2009 influenza pandemic and narcolepsy. There was consensus that an increased risk of narcolepsy was consistently observed after Pandemrix (AS03-adjuvanted) vaccine, but similar associations following Arepanrix (AS03-adjuvanted) or Focetria (MF59-adjuvanted) vaccines were not observed. Whether the differences are due to vaccine composition or other factors such as the timing of large-scale vaccination programs relative to H1N1pdm09 wild-type virus circulation in different geographic regions is not clear. The limitations of retrospective observational methodologies could also be contributing to some of the differences across studies. More basic and epidemiologic research is needed to further elucidate the association between adjuvanted influenza vaccine and narcolepsy and its mechanism and to inform planning and preparation for vaccination programs in advance of the next influenza pandemic.</AbstractText>
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<ForeName>Christopher</ForeName>
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Meeting report narcolepsy and pandemic influenza vaccination: What we know and what we need to know before the next pandemic? A report from the 2nd IABS meeting.

Meeting report narcolepsy and pandemic influenza vaccination: What we know and what we need to know before the next pandemic? A report from the 2nd IABS meeting.

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