Antiviral medication use in a cohort of pregnant women during the 2009-2010 influenza pandemic.
Identifieur interne : 001949 ( Ncbi/Curation ); précédent : 001948; suivant : 001950Antiviral medication use in a cohort of pregnant women during the 2009-2010 influenza pandemic.
Auteurs : A S Yasseen [Canada] ; D B Fell [Canada] ; A E Sprague [Canada] ; R. Xie [Canada] ; G. Smith [Canada] ; M C Walker [Canada] ; S W Wen [Canada]Source :
- Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology [ 1364-6893 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Antiviraux (administration et posologie), Antiviraux (usage thérapeutique), Comorbidité, Complications de la grossesse et maladies infectieuses (), Complications de la grossesse et maladies infectieuses (traitement médicamenteux), Femelle, Grippe humaine (), Grippe humaine (traitement médicamenteux), Grippe humaine (épidémiologie), Grossesse, Grossesse multiple, Humains, Ontario (épidémiologie), Pandémies, Sous-type H1N1 du virus de la grippe A, Tabagisme, Vaccins antigrippaux (administration et posologie), Émigrants et immigrants, Études de cohortes.
- MESH :
- administration et posologie : Antiviraux, Vaccins antigrippaux.
- traitement médicamenteux : Complications de la grossesse et maladies infectieuses, Grippe humaine.
- usage thérapeutique : Antiviraux.
- épidémiologie : Grippe humaine, Ontario.
- Adulte, Comorbidité, Complications de la grossesse et maladies infectieuses, Femelle, Grippe humaine, Grossesse, Grossesse multiple, Humains, Pandémies, Sous-type H1N1 du virus de la grippe A, Tabagisme, Émigrants et immigrants, Études de cohortes.
English descriptors
- KwdEn :
- Adult, Antiviral Agents (administration & dosage), Antiviral Agents (therapeutic use), Cohort Studies, Comorbidity, Emigrants and Immigrants, Female, Humans, Influenza A Virus, H1N1 Subtype, Influenza Vaccines (administration & dosage), Influenza, Human (drug therapy), Influenza, Human (epidemiology), Influenza, Human (prevention & control), Ontario (epidemiology), Pandemics, Pregnancy, Pregnancy Complications, Infectious (drug therapy), Pregnancy Complications, Infectious (prevention & control), Pregnancy, Multiple, Smoking.
- MESH :
- chemical , administration & dosage : Antiviral Agents, Influenza Vaccines.
- chemical , therapeutic use : Antiviral Agents.
- geographic , epidemiology : Ontario.
- drug therapy : Influenza, Human, Pregnancy Complications, Infectious.
- epidemiology : Influenza, Human.
- prevention & control : Influenza, Human, Pregnancy Complications, Infectious.
- Adult, Cohort Studies, Comorbidity, Emigrants and Immigrants, Female, Humans, Influenza A Virus, H1N1 Subtype, Pandemics, Pregnancy, Pregnancy, Multiple, Smoking.
Abstract
Preventing influenza-like illness (ILI) during pregnancy with antiviral medication use (AVMU) can mitigate serious health risks to mother and foetus. We report on AVMU in pregnant women in Ontario, Canada, and describe characteristics of AVMU during the 2009-2010 H1N1 pandemic. Rates and risk estimates of AVMU were compared across multiple categories and stratified across ILI infection status. Increased AVMU was observed in women with influenza infections, active smokers, those vaccinated against influenza, and those with pre-existing co-morbidities. Decreased AVMU was observed in women with multiple gestations, and those in neighbourhoods of high immigrant concentrations. Our stratified analysis indicated that the observed patterns differed by ILI infection status. We demonstrated that once infected, women across multiple groups were equally likely to use antiviral medications. In this report we also propose possible clinical explanations for the observed differences in AVMU, which will be useful in planning prevention initiatives for future pandemics.
DOI: 10.3109/01443615.2014.978846
PubMed: 25409120
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pubmed:25409120Le document en format XML
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<term>Antiviral Agents (therapeutic use)</term>
<term>Cohort Studies</term>
<term>Comorbidity</term>
<term>Emigrants and Immigrants</term>
<term>Female</term>
<term>Humans</term>
<term>Influenza A Virus, H1N1 Subtype</term>
<term>Influenza Vaccines (administration & dosage)</term>
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<term>Antiviraux (administration et posologie)</term>
<term>Antiviraux (usage thérapeutique)</term>
<term>Comorbidité</term>
<term>Complications de la grossesse et maladies infectieuses ()</term>
<term>Complications de la grossesse et maladies infectieuses (traitement médicamenteux)</term>
<term>Femelle</term>
<term>Grippe humaine ()</term>
<term>Grippe humaine (traitement médicamenteux)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Grossesse</term>
<term>Grossesse multiple</term>
<term>Humains</term>
<term>Ontario (épidémiologie)</term>
<term>Pandémies</term>
<term>Sous-type H1N1 du virus de la grippe A</term>
<term>Tabagisme</term>
<term>Vaccins antigrippaux (administration et posologie)</term>
<term>Émigrants et immigrants</term>
<term>Études de cohortes</term>
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<term>Influenza Vaccines</term>
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<term>Vaccins antigrippaux</term>
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<term>Pregnancy Complications, Infectious</term>
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<term>Emigrants and Immigrants</term>
<term>Female</term>
<term>Humans</term>
<term>Influenza A Virus, H1N1 Subtype</term>
<term>Pandemics</term>
<term>Pregnancy</term>
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<term>Complications de la grossesse et maladies infectieuses</term>
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<term>Grippe humaine</term>
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<term>Grossesse multiple</term>
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<term>Pandémies</term>
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<front><div type="abstract" xml:lang="en">Preventing influenza-like illness (ILI) during pregnancy with antiviral medication use (AVMU) can mitigate serious health risks to mother and foetus. We report on AVMU in pregnant women in Ontario, Canada, and describe characteristics of AVMU during the 2009-2010 H1N1 pandemic. Rates and risk estimates of AVMU were compared across multiple categories and stratified across ILI infection status. Increased AVMU was observed in women with influenza infections, active smokers, those vaccinated against influenza, and those with pre-existing co-morbidities. Decreased AVMU was observed in women with multiple gestations, and those in neighbourhoods of high immigrant concentrations. Our stratified analysis indicated that the observed patterns differed by ILI infection status. We demonstrated that once infected, women across multiple groups were equally likely to use antiviral medications. In this report we also propose possible clinical explanations for the observed differences in AVMU, which will be useful in planning prevention initiatives for future pandemics. </div>
</front>
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