Children under 10 years of age were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic in Canada: possible cohort effect following the 2009 influenza pandemic
Identifieur interne : 001F38 ( Ncbi/Checkpoint ); précédent : 001F37; suivant : 001F39Children under 10 years of age were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic in Canada: possible cohort effect following the 2009 influenza pandemic
Auteurs : Danuta M. Skowronski [Canada] ; Siobhan Leir [Canada] ; Gaston De Serres [Canada] ; Michelle Murti [Canada] ; James A. Dickinson [Canada] ; Anne-Luise Winter [Canada] ; Romy Olsha [Canada] ; Matthew A. Croxen [Canada] ; Steven J. Drews [Canada] ; Hugues Charest [Canada] ; Christine Martineau [Canada] ; Suzana Sabaiduc [Canada] ; Nathalie Bastien [Canada] ; Yan Li [Canada] ; Martin Petric [Canada] ; Agatha Jassem [Canada] ; Mel Krajden [Canada] ; Jonathan B. Gubbay [Canada]Source :
- Eurosurveillance [ 1025-496X ] ; 2019.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Canada (épidémiologie), Effet de cohorte, Enfant, Enfant d'âge préscolaire, Femelle, Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains, Jeune adulte, Mâle, Répartition par âge, Saisons, Sous-type H1N1 du virus de la grippe A (isolement et purification), Sujet âgé, Surveillance sentinelle, Épidémies.
- MESH :
- isolement et purification : Sous-type H1N1 du virus de la grippe A.
- virologie : Grippe humaine.
- épidémiologie : Canada, Grippe humaine.
- Adolescent, Adulte, Adulte d'âge moyen, Effet de cohorte, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Jeune adulte, Mâle, Répartition par âge, Saisons, Sujet âgé, Surveillance sentinelle, Épidémies.
- Wicri :
- geographic : Canada.
English descriptors
- KwdEn :
- Adolescent, Adult, Age Distribution, Aged, Canada (epidemiology), Child, Child, Preschool, Cohort Effect, Epidemics, Female, Humans, Influenza A Virus, H1N1 Subtype (isolation & purification), Influenza, Human (epidemiology), Influenza, Human (virology), Male, Middle Aged, Seasons, Sentinel Surveillance, Young Adult.
- MESH :
- geographic , epidemiology : Canada.
- epidemiology : Influenza, Human.
- isolation & purification : Influenza A Virus, H1N1 Subtype.
- virology : Influenza, Human.
- Adolescent, Adult, Age Distribution, Aged, Child, Child, Preschool, Cohort Effect, Epidemics, Female, Humans, Male, Middle Aged, Seasons, Sentinel Surveillance, Young Adult.
Abstract
Findings from the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN) suggest children were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic.
To compare the age distribution of A(H1N1)pdm09 cases in 2018/19 to prior seasonal influenza epidemics in Canada.
The age distribution of unvaccinated influenza A(H1N1)pdm09 cases and test-negative controls were compared across A(H1N1)pdm09-dominant epidemics in 2018/19, 2015/16 and 2013/14 and with the general population of SPSN provinces. Similar comparisons were undertaken for influenza A(H3N2)-dominant epidemics.
In 2018/19, more influenza A(H1N1)pdm09 cases were under 10 years old than controls (29% vs 16%; p < 0.001). In particular, children aged 5–9 years comprised 14% of cases, greater than their contribution to controls (4%) or the general population (5%) and at least twice their contribution in 2015/16 (7%; p < 0.001) or 2013/14 (5%; p < 0.001). Conversely, children aged 10–19 years (11% of the population) were under-represented among A(H1N1)pdm09 cases versus controls in 2018/19 (7% vs 12%; p < 0.001), 2015/16 (7% vs 13%; p < 0.001) and 2013/14 (9% vs 12%; p = 0.12).
Children under 10 years old contributed more to outpatient A(H1N1)pdm09 medical visits in 2018/19 than prior seasonal epidemics in Canada. In 2018/19, all children under 10 years old were born after the 2009 A(H1N1)pdm09 pandemic and therefore lacked pandemic-induced immunity. In addition, more than half those born after 2009 now attend school (i.e. 5–9-year-olds), a socio-behavioural context that may enhance transmission and did not apply during prior A(H1N1)pdm09 epidemics.
Url:
DOI: 10.2807/1560-7917.ES.2019.24.15.1900104
PubMed: 30994107
PubMed Central: 6470369
Affiliations:
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Skowronski</name><affiliation wicri:level="1"><nlm:aff id="aff1">British Columbia Centre for Disease Control, Vancouver, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>British Columbia Centre for Disease Control, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">University of British Columbia, Vancouver, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation></author><author><name sortKey="Leir, Siobhan" sort="Leir, Siobhan" uniqKey="Leir S" first="Siobhan" last="Leir">Siobhan Leir</name><affiliation wicri:level="1"><nlm:aff id="aff1">British Columbia Centre for Disease Control, Vancouver, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>British Columbia Centre for Disease Control, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation></author><author><name sortKey="De Serres, Gaston" sort="De Serres, Gaston" uniqKey="De Serres G" first="Gaston" last="De Serres">Gaston De Serres</name><affiliation wicri:level="1"><nlm:aff id="aff3">Institut National de Santé Publique du Québec, Quebec, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Institut National de Santé Publique du Québec, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4">Laval University, Quebec, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Laval University, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5">Centre Hospitalier Universitaire de Québec, Quebec, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Centre Hospitalier Universitaire de Québec, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Murti, Michelle" sort="Murti, Michelle" uniqKey="Murti M" first="Michelle" last="Murti">Michelle Murti</name><affiliation wicri:level="1"><nlm:aff id="aff6">Public Health Ontario, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Ontario, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="aff7">University of Toronto, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Dickinson, James A" sort="Dickinson, James A" uniqKey="Dickinson J" first="James A" last="Dickinson">James A. Dickinson</name><affiliation wicri:level="4"><nlm:aff id="aff8">University of Calgary, Calgary, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>University of Calgary, Calgary</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Winter, Anne Luise" sort="Winter, Anne Luise" uniqKey="Winter A" first="Anne-Luise" last="Winter">Anne-Luise Winter</name><affiliation wicri:level="1"><nlm:aff id="aff6">Public Health Ontario, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Ontario, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Olsha, Romy" sort="Olsha, Romy" uniqKey="Olsha R" first="Romy" last="Olsha">Romy Olsha</name><affiliation wicri:level="1"><nlm:aff id="aff6">Public Health Ontario, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Ontario, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Croxen, Matthew A" sort="Croxen, Matthew A" uniqKey="Croxen M" first="Matthew A" last="Croxen">Matthew A. Croxen</name><affiliation wicri:level="1"><nlm:aff id="aff9">Provincial Laboratory for Public Health, Edmonton, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Provincial Laboratory for Public Health, Edmonton</wicri:regionArea><wicri:noRegion>Edmonton</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff10">University of Alberta, Edmonton, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>University of Alberta, Edmonton</wicri:regionArea><wicri:noRegion>Edmonton</wicri:noRegion></affiliation></author><author><name sortKey="Drews, Steven J" sort="Drews, Steven J" uniqKey="Drews S" first="Steven J" last="Drews">Steven J. Drews</name><affiliation wicri:level="1"><nlm:aff id="aff9">Provincial Laboratory for Public Health, Edmonton, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Provincial Laboratory for Public Health, Edmonton</wicri:regionArea><wicri:noRegion>Edmonton</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff10">University of Alberta, Edmonton, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>University of Alberta, Edmonton</wicri:regionArea><wicri:noRegion>Edmonton</wicri:noRegion></affiliation></author><author><name sortKey="Charest, Hugues" sort="Charest, Hugues" uniqKey="Charest H" first="Hugues" last="Charest">Hugues Charest</name><affiliation wicri:level="1"><nlm:aff id="aff3">Institut National de Santé Publique du Québec, Quebec, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Institut National de Santé Publique du Québec, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Martineau, Christine" sort="Martineau, Christine" uniqKey="Martineau C" first="Christine" last="Martineau">Christine Martineau</name><affiliation wicri:level="1"><nlm:aff id="aff3">Institut National de Santé Publique du Québec, Quebec, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Institut National de Santé Publique du Québec, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Sabaiduc, Suzana" sort="Sabaiduc, Suzana" uniqKey="Sabaiduc S" first="Suzana" last="Sabaiduc">Suzana Sabaiduc</name><affiliation wicri:level="1"><nlm:aff id="aff1">British Columbia Centre for Disease Control, Vancouver, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>British Columbia Centre for Disease Control, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation></author><author><name sortKey="Bastien, Nathalie" sort="Bastien, Nathalie" uniqKey="Bastien N" first="Nathalie" last="Bastien">Nathalie Bastien</name><affiliation wicri:level="1"><nlm:aff id="aff11">National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg</wicri:regionArea><wicri:noRegion>Winnipeg</wicri:noRegion></affiliation></author><author><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name><affiliation wicri:level="1"><nlm:aff id="aff11">National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg</wicri:regionArea><wicri:noRegion>Winnipeg</wicri:noRegion></affiliation></author><author><name sortKey="Petric, Martin" sort="Petric, Martin" uniqKey="Petric M" first="Martin" last="Petric">Martin Petric</name><affiliation wicri:level="1"><nlm:aff id="aff2">University of British Columbia, Vancouver, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation></author><author><name sortKey="Jassem, Agatha" sort="Jassem, Agatha" uniqKey="Jassem A" first="Agatha" last="Jassem">Agatha Jassem</name><affiliation wicri:level="1"><nlm:aff id="aff1">British Columbia Centre for Disease Control, Vancouver, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>British Columbia Centre for Disease Control, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">University of British Columbia, Vancouver, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation></author><author><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><affiliation wicri:level="1"><nlm:aff id="aff1">British Columbia Centre for Disease Control, Vancouver, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>British Columbia Centre for Disease Control, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">University of British Columbia, Vancouver, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation></author><author><name sortKey="Gubbay, Jonathan B" sort="Gubbay, Jonathan B" uniqKey="Gubbay J" first="Jonathan B" last="Gubbay">Jonathan B. Gubbay</name><affiliation wicri:level="1"><nlm:aff id="aff6">Public Health Ontario, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Ontario, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="aff7">University of Toronto, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author></analytic><series><title level="j">Eurosurveillance</title><idno type="ISSN">1025-496X</idno><idno type="eISSN">1560-7917</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Age Distribution</term><term>Aged</term><term>Canada (epidemiology)</term><term>Child</term><term>Child, Preschool</term><term>Cohort Effect</term><term>Epidemics</term><term>Female</term><term>Humans</term><term>Influenza A Virus, H1N1 Subtype (isolation & purification)</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (virology)</term><term>Male</term><term>Middle Aged</term><term>Seasons</term><term>Sentinel Surveillance</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Canada (épidémiologie)</term><term>Effet de cohorte</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Grippe humaine (virologie)</term><term>Grippe humaine (épidémiologie)</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Répartition par âge</term><term>Saisons</term><term>Sous-type H1N1 du virus de la grippe A (isolement et purification)</term><term>Sujet âgé</term><term>Surveillance sentinelle</term><term>Épidémies</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Canada</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Sous-type H1N1 du virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Canada</term><term>Grippe humaine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Age Distribution</term><term>Aged</term><term>Child</term><term>Child, Preschool</term><term>Cohort Effect</term><term>Epidemics</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Seasons</term><term>Sentinel Surveillance</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Effet de cohorte</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Répartition par âge</term><term>Saisons</term><term>Sujet âgé</term><term>Surveillance sentinelle</term><term>Épidémies</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Canada</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Introduction</title><p>Findings from the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN) suggest children were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic.</p></sec><sec><title>Aim</title><p>To compare the age distribution of A(H1N1)pdm09 cases in 2018/19 to prior seasonal influenza epidemics in Canada.</p></sec><sec><title>Methods</title><p>The age distribution of unvaccinated influenza A(H1N1)pdm09 cases and test-negative controls were compared across A(H1N1)pdm09-dominant epidemics in 2018/19, 2015/16 and 2013/14 and with the general population of SPSN provinces. Similar comparisons were undertaken for influenza A(H3N2)-dominant epidemics.</p></sec><sec><title>Results</title><p>In 2018/19, more influenza A(H1N1)pdm09 cases were under 10 years old than controls (29% vs 16%; p < 0.001). In particular, children aged 5–9 years comprised 14% of cases, greater than their contribution to controls (4%) or the general population (5%) and at least twice their contribution in 2015/16 (7%; p < 0.001) or 2013/14 (5%; p < 0.001). Conversely, children aged 10–19 years (11% of the population) were under-represented among A(H1N1)pdm09 cases versus controls in 2018/19 (7% vs 12%; p < 0.001), 2015/16 (7% vs 13%; p < 0.001) and 2013/14 (9% vs 12%; p = 0.12).</p></sec><sec><title>Conclusion</title><p>Children under 10 years old contributed more to outpatient A(H1N1)pdm09 medical visits in 2018/19 than prior seasonal epidemics in Canada. In 2018/19, all children under 10 years old were born after the 2009 A(H1N1)pdm09 pandemic and therefore lacked pandemic-induced immunity. In addition, more than half those born after 2009 now attend school (i.e. 5–9-year-olds), a socio-behavioural context that may enhance transmission and did not apply during prior A(H1N1)pdm09 epidemics.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Segaloff, H" uniqKey="Segaloff H">H Segaloff</name></author><author><name sortKey="Melidou, A" uniqKey="Melidou A">A Melidou</name></author><author><name sortKey="Adlhoch, C" uniqKey="Adlhoch C">C Adlhoch</name></author><author><name sortKey="Pereyaslov, D" uniqKey="Pereyaslov D">D Pereyaslov</name></author><author><name sortKey="Robesyn, E" uniqKey="Robesyn E">E Robesyn</name></author><author><name sortKey="Penttinen, P" uniqKey="Penttinen P">P Penttinen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skowronski, Dm" uniqKey="Skowronski D">DM 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sortKey="Belongia, Ea" uniqKey="Belongia E">EA Belongia</name></author><author><name sortKey="Simpson, Md" uniqKey="Simpson M">MD Simpson</name></author><author><name sortKey="King, Jp" uniqKey="King J">JP King</name></author><author><name sortKey="Sundaram, Me" uniqKey="Sundaram M">ME Sundaram</name></author><author><name sortKey="Kelley, Ns" uniqKey="Kelley N">NS Kelley</name></author><author><name sortKey="Osterholm, Mt" uniqKey="Osterholm M">MT Osterholm</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Grohskopf, La" uniqKey="Grohskopf L">LA Grohskopf</name></author><author><name sortKey="Sokolow, Lz" uniqKey="Sokolow L">LZ Sokolow</name></author><author><name sortKey="Broder, Kr" uniqKey="Broder K">KR Broder</name></author><author><name sortKey="Olsen, Sj" uniqKey="Olsen S">SJ Olsen</name></author><author><name sortKey="Karron, Ra" uniqKey="Karron R">RA Karron</name></author><author><name sortKey="Jernigan, Db" 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Blanton</name></author><author><name sortKey="Brammer, L" uniqKey="Brammer L">L Brammer</name></author><author><name sortKey="Olsen, Sj" uniqKey="Olsen S">SJ Olsen</name></author><author><name sortKey="Fry, Am" uniqKey="Fry A">AM Fry</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Donaldson, Lj" uniqKey="Donaldson L">LJ Donaldson</name></author><author><name sortKey="Rutter, Pd" uniqKey="Rutter P">PD Rutter</name></author><author><name sortKey="Ellis, Bm" uniqKey="Ellis B">BM Ellis</name></author><author><name sortKey="Greaves, Fe" uniqKey="Greaves F">FE Greaves</name></author><author><name sortKey="Mytton, Ot" uniqKey="Mytton O">OT Mytton</name></author><author><name sortKey="Pebody, Rg" uniqKey="Pebody R">RG Pebody</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kostova, D" uniqKey="Kostova D">D Kostova</name></author><author><name sortKey="Reed, C" uniqKey="Reed C">C Reed</name></author><author><name sortKey="Finelli, L" uniqKey="Finelli L">L Finelli</name></author><author><name sortKey="Cheng, P Y" uniqKey="Cheng P">P-Y Cheng</name></author><author><name sortKey="Gargiullo, Pm" uniqKey="Gargiullo P">PM Gargiullo</name></author><author><name sortKey="Shay, Dk" uniqKey="Shay D">DK Shay</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Canada</li></country><region><li>Alberta</li><li>Ontario</li></region><settlement><li>Calgary</li><li>Toronto</li></settlement><orgName><li>Université de Calgary</li><li>Université de Toronto</li></orgName></list><tree><country name="Canada"><noRegion><name sortKey="Skowronski, Danuta M" sort="Skowronski, Danuta M" uniqKey="Skowronski D" first="Danuta M" last="Skowronski">Danuta M. Skowronski</name></noRegion><name sortKey="Bastien, Nathalie" sort="Bastien, Nathalie" uniqKey="Bastien N" first="Nathalie" last="Bastien">Nathalie Bastien</name><name sortKey="Charest, Hugues" sort="Charest, Hugues" uniqKey="Charest H" first="Hugues" last="Charest">Hugues Charest</name><name sortKey="Croxen, Matthew A" sort="Croxen, Matthew A" uniqKey="Croxen M" first="Matthew A" last="Croxen">Matthew A. Croxen</name><name sortKey="Croxen, Matthew A" sort="Croxen, Matthew A" uniqKey="Croxen M" first="Matthew A" last="Croxen">Matthew A. Croxen</name><name sortKey="De Serres, Gaston" sort="De Serres, Gaston" uniqKey="De Serres G" first="Gaston" last="De Serres">Gaston De Serres</name><name sortKey="De Serres, Gaston" sort="De Serres, Gaston" uniqKey="De Serres G" first="Gaston" last="De Serres">Gaston De Serres</name><name sortKey="De Serres, Gaston" sort="De Serres, Gaston" uniqKey="De Serres G" first="Gaston" last="De Serres">Gaston De Serres</name><name sortKey="Dickinson, James A" sort="Dickinson, James A" uniqKey="Dickinson J" first="James A" last="Dickinson">James A. Dickinson</name><name sortKey="Drews, Steven J" sort="Drews, Steven J" uniqKey="Drews S" first="Steven J" last="Drews">Steven J. Drews</name><name sortKey="Drews, Steven J" sort="Drews, Steven J" uniqKey="Drews S" first="Steven J" last="Drews">Steven J. Drews</name><name sortKey="Gubbay, Jonathan B" sort="Gubbay, Jonathan B" uniqKey="Gubbay J" first="Jonathan B" last="Gubbay">Jonathan B. Gubbay</name><name sortKey="Gubbay, Jonathan B" sort="Gubbay, Jonathan B" uniqKey="Gubbay J" first="Jonathan B" last="Gubbay">Jonathan B. Gubbay</name><name sortKey="Jassem, Agatha" sort="Jassem, Agatha" uniqKey="Jassem A" first="Agatha" last="Jassem">Agatha Jassem</name><name sortKey="Jassem, Agatha" sort="Jassem, Agatha" uniqKey="Jassem A" first="Agatha" last="Jassem">Agatha Jassem</name><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><name sortKey="Leir, Siobhan" sort="Leir, Siobhan" uniqKey="Leir S" first="Siobhan" last="Leir">Siobhan Leir</name><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name><name sortKey="Martineau, Christine" sort="Martineau, Christine" uniqKey="Martineau C" first="Christine" last="Martineau">Christine Martineau</name><name sortKey="Murti, Michelle" sort="Murti, Michelle" uniqKey="Murti M" first="Michelle" last="Murti">Michelle Murti</name><name sortKey="Murti, Michelle" sort="Murti, Michelle" uniqKey="Murti M" first="Michelle" last="Murti">Michelle Murti</name><name sortKey="Olsha, Romy" sort="Olsha, Romy" uniqKey="Olsha R" first="Romy" last="Olsha">Romy Olsha</name><name sortKey="Petric, Martin" sort="Petric, Martin" uniqKey="Petric M" first="Martin" last="Petric">Martin Petric</name><name sortKey="Sabaiduc, Suzana" sort="Sabaiduc, Suzana" uniqKey="Sabaiduc S" first="Suzana" last="Sabaiduc">Suzana Sabaiduc</name><name sortKey="Skowronski, Danuta M" sort="Skowronski, Danuta M" uniqKey="Skowronski D" first="Danuta M" last="Skowronski">Danuta M. Skowronski</name><name sortKey="Winter, Anne Luise" sort="Winter, Anne Luise" uniqKey="Winter A" first="Anne-Luise" last="Winter">Anne-Luise Winter</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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