[The use of antiviral agents during an (impending) influenza pandemic].
Identifieur interne : 004C93 ( Main/Merge ); précédent : 004C92; suivant : 004C94[The use of antiviral agents during an (impending) influenza pandemic].
Auteurs : W. Opstelten ; J E Van Steenbergen ; G A Van Essen ; M A B. Van Der SandeSource :
- Nederlands tijdschrift voor geneeskunde [ 0028-2162 ] ; 2007.
Descripteurs français
- KwdFr :
- MESH :
- antagonistes et inhibiteurs : Sialidase.
- traitement médicamenteux : Grippe humaine.
- usage thérapeutique : Antiviraux.
- épidémiologie : Grippe humaine.
- Flambées de maladies, Grippe humaine, Humains, Vaccins antigrippaux.
English descriptors
- KwdEn :
- MESH :
- chemical , antagonists & inhibitors : Neuraminidase.
- chemical , therapeutic use : Antiviral Agents.
- drug therapy : Influenza, Human.
- epidemiology : Influenza, Human.
- prevention & control : Disease Outbreaks, Influenza, Human.
- Humans, Influenza Vaccines.
Abstract
The preventive and therapeutic principles during an (impending) influenza pandemic differ fundamentally from those prevailing during the annual episodes ofinfluenza. Pending the availability of an effective pandemic vaccine, neuraminidase inhibitors are the only effective agents for the prevention and treatment of infections caused by a pandemic influenza virus. The development of an influenza pandemic has 6 phases: phases 3-5 reflect an increasing threat; phase 6 represents a manifest pandemic. During phases 3-5, a maximum effort is made to prevent or delay a pandemic. Neuraminidase inhibitors should be given not only to patients but also to their close contacts (post-exposure prophylaxis). During phase 6, post-exposure prophylaxis is no longer indicated and neuraminidase inhibitors are prescribed for all patients with symptoms ofpandemic influenza. Prophylaxis without preceding close contact with an influenza patient (primary prophylaxis) is recommended only in exceptional cases. Physicians should not prescribe antiviral drugs on demand to concerned citizens for stockpiling.
PubMed: 17508684
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pubmed:17508684Le document en format XML
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<term>Disease Outbreaks (prevention & control)</term>
<term>Humans</term>
<term>Influenza Vaccines</term>
<term>Influenza, Human (drug therapy)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (prevention & control)</term>
<term>Neuraminidase (antagonists & inhibitors)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Antiviraux (usage thérapeutique)</term>
<term>Flambées de maladies ()</term>
<term>Grippe humaine ()</term>
<term>Grippe humaine (traitement médicamenteux)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Humains</term>
<term>Sialidase (antagonistes et inhibiteurs)</term>
<term>Vaccins antigrippaux</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="antagonists & inhibitors" xml:lang="en"><term>Neuraminidase</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term>
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<keywords scheme="MESH" qualifier="antagonistes et inhibiteurs" xml:lang="fr"><term>Sialidase</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Influenza, Human</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term>
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<term>Grippe humaine</term>
<term>Humains</term>
<term>Vaccins antigrippaux</term>
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<front><div type="abstract" xml:lang="en">The preventive and therapeutic principles during an (impending) influenza pandemic differ fundamentally from those prevailing during the annual episodes ofinfluenza. Pending the availability of an effective pandemic vaccine, neuraminidase inhibitors are the only effective agents for the prevention and treatment of infections caused by a pandemic influenza virus. The development of an influenza pandemic has 6 phases: phases 3-5 reflect an increasing threat; phase 6 represents a manifest pandemic. During phases 3-5, a maximum effort is made to prevent or delay a pandemic. Neuraminidase inhibitors should be given not only to patients but also to their close contacts (post-exposure prophylaxis). During phase 6, post-exposure prophylaxis is no longer indicated and neuraminidase inhibitors are prescribed for all patients with symptoms ofpandemic influenza. Prophylaxis without preceding close contact with an influenza patient (primary prophylaxis) is recommended only in exceptional cases. Physicians should not prescribe antiviral drugs on demand to concerned citizens for stockpiling.</div>
</front>
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