Effect of four neuraminidase inhibitors on influenza in Osaka, Japan: An eight‐year survey
Identifieur interne : 000351 ( Main/Merge ); précédent : 000350; suivant : 000352Effect of four neuraminidase inhibitors on influenza in Osaka, Japan: An eight‐year survey
Auteurs : Yoshihiro Tochino ; Naoko Yoshii ; Masashi Fujioka ; Takashi Hamazaki ; Tomoya Kawaguchi ; Hiroshi Kakeya ; Taichi ShutoSource :
- Journal of General and Family Medicine [ 2189-6577 ] ; 2019.
Abstract
After the A/H1N1 influenza pandemic in 2009, two new drugs against influenza, namely laninamivir and peramivir, were released in 2010 in Japan. We investigated prescription trends of four neuraminidase inhibitors (NAIs), which are laninamivir, peramivir, oseltamivir, and zanamivir, and assessed clinical data related to influenza for 8 years.
Patients living in Osaka Prefecture and diagnosed with influenza responded to a postcard questionnaire that collected data regarding their demographic characteristics, symptoms including fever, prescribed drugs, and influenza type.
Laninamivir was most prescribed to patients aged ≥ 10 years, and oseltamivir was most prescribed to patients aged < 10 years. All four NAIs had similar effects on influenza. Patients with type A influenza experienced fever alleviation earlier than those with type B influenza. Older patients tended to have lower fever. Most seasons had similar results.
Our descriptive epidemiologic study revealed the status of patients with influenza and their medication use.
Url:
DOI: 10.1002/jgf2.286
PubMed: 31911885
PubMed Central: 6942933
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PMC:6942933Le document en format XML
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<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<sec id="jgf2286-sec-0001"><title>Background</title>
<p>After the A/H1N1 influenza pandemic in 2009, two new drugs against influenza, namely laninamivir and peramivir, were released in 2010 in Japan. We investigated prescription trends of four neuraminidase inhibitors (NAIs), which are laninamivir, peramivir, oseltamivir, and zanamivir, and assessed clinical data related to influenza for 8 years.</p>
</sec>
<sec id="jgf2286-sec-0002"><title>Methods</title>
<p>Patients living in Osaka Prefecture and diagnosed with influenza responded to a postcard questionnaire that collected data regarding their demographic characteristics, symptoms including fever, prescribed drugs, and influenza type.</p>
</sec>
<sec id="jgf2286-sec-0003"><title>Results</title>
<p>Laninamivir was most prescribed to patients aged ≥ 10 years, and oseltamivir was most prescribed to patients aged < 10 years. All four NAIs had similar effects on influenza. Patients with type A influenza experienced fever alleviation earlier than those with type B influenza. Older patients tended to have lower fever. Most seasons had similar results.</p>
</sec>
<sec id="jgf2286-sec-0004"><title>Conclusions</title>
<p>Our descriptive epidemiologic study revealed the status of patients with influenza and their medication use.</p>
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