AI-based multi-modal integration of clinical characteristics, lab tests and chest CTs improves COVID-19 outcome prediction of hospitalized patients
Identifieur interne : 000023 ( Main/Merge ); précédent : 000022; suivant : 000024AI-based multi-modal integration of clinical characteristics, lab tests and chest CTs improves COVID-19 outcome prediction of hospitalized patients
Auteurs : Nathalie Lassau [France] ; Samy Ammari [France] ; Emilie Chouzenoux [France] ; Hugo Gortais [France] ; Paul Herent [États-Unis] ; Matthieu Devilder [France] ; Samer Soliman [France] ; Olivier Meyrignac [France] ; Marie-Pauline Talabard [France] ; Jean-Philippe Lamarque [France] ; Rémy Dubois [États-Unis] ; Nicolas Loiseau [États-Unis] ; Paul Trichelair [États-Unis] ; Etienne Bendjebbar [États-Unis] ; Gabriel Garcia [France] ; Corinne Balleyguier [France] ; Mansouria Merad [France] ; Annabelle Stoclin [France] ; Simon Jegou [États-Unis] ; Franck Griscelli [France] ; Nicolas Tetelboum [France] ; Yingping Li [France] ; Sagar Verma [France] ; Matthieu Terris [France] ; Tasnim Dardouri [France] ; Kavya Gupta [France] ; Ana Neacsu [France] ; Frank Chemouni [France] ; Meriem Sefta [États-Unis] ; Paul Jehanno [États-Unis] ; Imad Bousaid [France] ; Yannick Boursin [France] ; Emmanuel Planchet [France] ; Mikael Azoulay [France] ; Jocelyn Dachary [États-Unis] ; Fabien Brulport [États-Unis] ; Adrián González [États-Unis] ; Olivier Dehaene [États-Unis] ; Jean-Baptiste Schiratti [États-Unis] ; Kathryn Schutte [États-Unis] ; Jean-Christophe Pesquet [France] ; Hugues Talbot [France] ; Elodie Pronier [États-Unis] ; Gilles Wainrib [États-Unis] ; Thomas Clozel [États-Unis] ; Fabrice Barlesi [France] ; Marie-France Bellin [France] ; Michael Blum [États-Unis]Source :
Abstract
With 15% of severe cases among hospitalized patients, the SARS-COV-2 pandemic has put tremendous pressure on Intensive Care Units, and made the identification of early predictors of future severity a public health priority. We collected clinical and biological data, as well as CT scan images and radiology reports from 1,003 coronavirus-infected patients from two French hospitals. Radiologists' manual CT annotations were also available. We first identified 11 clinical variables and 3 types of radiologist-reported features significantly associated with prognosis. Next, focusing on the CT images, we trained deep learning models to automatically segment the scans and reproduce radiologists' annotations. We also built CT image-based deep learning models that predicted future severity better than models based on the radiologists' scan reports. Finally, we showed that including CT scan features alongside the clinical and biological data yielded more accurate predictions than using clinical and biological data alone. These findings show that CT scans provide insightful early predictors of future severity.
Url:
Links toward previous steps (curation, corpus...)
- to stream Hal, to step Corpus: 000034
- to stream Hal, to step Curation: 000034
- to stream Hal, to step Checkpoint: 000023
Links to Exploration step
Hal:hal-02586111Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">AI-based multi-modal integration of clinical characteristics, lab tests and chest CTs improves COVID-19 outcome prediction of hospitalized patients</title>
<author><name sortKey="Lassau, Nathalie" sort="Lassau, Nathalie" uniqKey="Lassau N" first="Nathalie" last="Lassau">Nathalie Lassau</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Ammari, Samy" sort="Ammari, Samy" uniqKey="Ammari S" first="Samy" last="Ammari">Samy Ammari</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Chouzenoux, Emilie" sort="Chouzenoux, Emilie" uniqKey="Chouzenoux E" first="Emilie" last="Chouzenoux">Emilie Chouzenoux</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Gortais, Hugo" sort="Gortais, Hugo" uniqKey="Gortais H" first="Hugo" last="Gortais">Hugo Gortais</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-312432" status="VALID"> <orgName>AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)</orgName>
<desc> <address> <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
<country key="FR"></country>
</address>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Herent, Paul" sort="Herent, Paul" uniqKey="Herent P" first="Paul" last="Herent">Paul Herent</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Devilder, Matthieu" sort="Devilder, Matthieu" uniqKey="Devilder M" first="Matthieu" last="Devilder">Matthieu Devilder</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-312432" status="VALID"> <orgName>AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)</orgName>
<desc> <address> <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
<country key="FR"></country>
</address>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Soliman, Samer" sort="Soliman, Samer" uniqKey="Soliman S" first="Samer" last="Soliman">Samer Soliman</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-312432" status="VALID"> <orgName>AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)</orgName>
<desc> <address> <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
<country key="FR"></country>
</address>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Meyrignac, Olivier" sort="Meyrignac, Olivier" uniqKey="Meyrignac O" first="Olivier" last="Meyrignac">Olivier Meyrignac</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-312432" status="VALID"> <orgName>AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)</orgName>
<desc> <address> <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
<country key="FR"></country>
</address>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Talabard, Marie Pauline" sort="Talabard, Marie Pauline" uniqKey="Talabard M" first="Marie-Pauline" last="Talabard">Marie-Pauline Talabard</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-312432" status="VALID"> <orgName>AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)</orgName>
<desc> <address> <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
<country key="FR"></country>
</address>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Lamarque, Jean Philippe" sort="Lamarque, Jean Philippe" uniqKey="Lamarque J" first="Jean-Philippe" last="Lamarque">Jean-Philippe Lamarque</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Dubois, Remy" sort="Dubois, Remy" uniqKey="Dubois R" first="Rémy" last="Dubois">Rémy Dubois</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Loiseau, Nicolas" sort="Loiseau, Nicolas" uniqKey="Loiseau N" first="Nicolas" last="Loiseau">Nicolas Loiseau</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Trichelair, Paul" sort="Trichelair, Paul" uniqKey="Trichelair P" first="Paul" last="Trichelair">Paul Trichelair</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Bendjebbar, Etienne" sort="Bendjebbar, Etienne" uniqKey="Bendjebbar E" first="Etienne" last="Bendjebbar">Etienne Bendjebbar</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Garcia, Gabriel" sort="Garcia, Gabriel" uniqKey="Garcia G" first="Gabriel" last="Garcia">Gabriel Garcia</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-456741" status="VALID"> <orgName>Département d'imagerie médicale [Gustave Roussy]</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-156104" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-156104" type="direct"><org type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Balleyguier, Corinne" sort="Balleyguier, Corinne" uniqKey="Balleyguier C" first="Corinne" last="Balleyguier">Corinne Balleyguier</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Merad, Mansouria" sort="Merad, Mansouria" uniqKey="Merad M" first="Mansouria" last="Merad">Mansouria Merad</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Stoclin, Annabelle" sort="Stoclin, Annabelle" uniqKey="Stoclin A" first="Annabelle" last="Stoclin">Annabelle Stoclin</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Jegou, Simon" sort="Jegou, Simon" uniqKey="Jegou S" first="Simon" last="Jegou">Simon Jegou</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Griscelli, Franck" sort="Griscelli, Franck" uniqKey="Griscelli F" first="Franck" last="Griscelli">Franck Griscelli</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Tetelboum, Nicolas" sort="Tetelboum, Nicolas" uniqKey="Tetelboum N" first="Nicolas" last="Tetelboum">Nicolas Tetelboum</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-456741" status="VALID"> <orgName>Département d'imagerie médicale [Gustave Roussy]</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-156104" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-156104" type="direct"><org type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Li, Yingping" sort="Li, Yingping" uniqKey="Li Y" first="Yingping" last="Li">Yingping Li</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Verma, Sagar" sort="Verma, Sagar" uniqKey="Verma S" first="Sagar" last="Verma">Sagar Verma</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Terris, Matthieu" sort="Terris, Matthieu" uniqKey="Terris M" first="Matthieu" last="Terris">Matthieu Terris</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Dardouri, Tasnim" sort="Dardouri, Tasnim" uniqKey="Dardouri T" first="Tasnim" last="Dardouri">Tasnim Dardouri</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Gupta, Kavya" sort="Gupta, Kavya" uniqKey="Gupta K" first="Kavya" last="Gupta">Kavya Gupta</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Neacsu, Ana" sort="Neacsu, Ana" uniqKey="Neacsu A" first="Ana" last="Neacsu">Ana Neacsu</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Chemouni, Frank" sort="Chemouni, Frank" uniqKey="Chemouni F" first="Frank" last="Chemouni">Frank Chemouni</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Sefta, Meriem" sort="Sefta, Meriem" uniqKey="Sefta M" first="Meriem" last="Sefta">Meriem Sefta</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Jehanno, Paul" sort="Jehanno, Paul" uniqKey="Jehanno P" first="Paul" last="Jehanno">Paul Jehanno</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Bousaid, Imad" sort="Bousaid, Imad" uniqKey="Bousaid I" first="Imad" last="Bousaid">Imad Bousaid</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Boursin, Yannick" sort="Boursin, Yannick" uniqKey="Boursin Y" first="Yannick" last="Boursin">Yannick Boursin</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Planchet, Emmanuel" sort="Planchet, Emmanuel" uniqKey="Planchet E" first="Emmanuel" last="Planchet">Emmanuel Planchet</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Azoulay, Mikael" sort="Azoulay, Mikael" uniqKey="Azoulay M" first="Mikael" last="Azoulay">Mikael Azoulay</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Dachary, Jocelyn" sort="Dachary, Jocelyn" uniqKey="Dachary J" first="Jocelyn" last="Dachary">Jocelyn Dachary</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Brulport, Fabien" sort="Brulport, Fabien" uniqKey="Brulport F" first="Fabien" last="Brulport">Fabien Brulport</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Gonzalez, Adrian" sort="Gonzalez, Adrian" uniqKey="Gonzalez A" first="Adrián" last="González">Adrián González</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Dehaene, Olivier" sort="Dehaene, Olivier" uniqKey="Dehaene O" first="Olivier" last="Dehaene">Olivier Dehaene</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Schiratti, Jean Baptiste" sort="Schiratti, Jean Baptiste" uniqKey="Schiratti J" first="Jean-Baptiste" last="Schiratti">Jean-Baptiste Schiratti</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Schutte, Kathryn" sort="Schutte, Kathryn" uniqKey="Schutte K" first="Kathryn" last="Schutte">Kathryn Schutte</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Pesquet, Jean Christophe" sort="Pesquet, Jean Christophe" uniqKey="Pesquet J" first="Jean-Christophe" last="Pesquet">Jean-Christophe Pesquet</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Talbot, Hugues" sort="Talbot, Hugues" uniqKey="Talbot H" first="Hugues" last="Talbot">Hugues Talbot</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Pronier, Elodie" sort="Pronier, Elodie" uniqKey="Pronier E" first="Elodie" last="Pronier">Elodie Pronier</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Wainrib, Gilles" sort="Wainrib, Gilles" uniqKey="Wainrib G" first="Gilles" last="Wainrib">Gilles Wainrib</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Clozel, Thomas" sort="Clozel, Thomas" uniqKey="Clozel T" first="Thomas" last="Clozel">Thomas Clozel</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Barlesi, Fabrice" sort="Barlesi, Fabrice" uniqKey="Barlesi F" first="Fabrice" last="Barlesi">Fabrice Barlesi</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Bellin, Marie France" sort="Bellin, Marie France" uniqKey="Bellin M" first="Marie-France" last="Bellin">Marie-France Bellin</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Blum, Michael" sort="Blum, Michael" uniqKey="Blum M" first="Michael" last="Blum">Michael Blum</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-02586111</idno>
<idno type="halId">hal-02586111</idno>
<idno type="halUri">https://hal.archives-ouvertes.fr/hal-02586111</idno>
<idno type="url">https://hal.archives-ouvertes.fr/hal-02586111</idno>
<date when="2020-05-15">2020-05-15</date>
<idno type="wicri:Area/Hal/Corpus">000034</idno>
<idno type="wicri:Area/Hal/Curation">000034</idno>
<idno type="wicri:Area/Hal/Checkpoint">000023</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000023</idno>
<idno type="wicri:Area/Main/Merge">000023</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">AI-based multi-modal integration of clinical characteristics, lab tests and chest CTs improves COVID-19 outcome prediction of hospitalized patients</title>
<author><name sortKey="Lassau, Nathalie" sort="Lassau, Nathalie" uniqKey="Lassau N" first="Nathalie" last="Lassau">Nathalie Lassau</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Ammari, Samy" sort="Ammari, Samy" uniqKey="Ammari S" first="Samy" last="Ammari">Samy Ammari</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Chouzenoux, Emilie" sort="Chouzenoux, Emilie" uniqKey="Chouzenoux E" first="Emilie" last="Chouzenoux">Emilie Chouzenoux</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Gortais, Hugo" sort="Gortais, Hugo" uniqKey="Gortais H" first="Hugo" last="Gortais">Hugo Gortais</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-312432" status="VALID"> <orgName>AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)</orgName>
<desc> <address> <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
<country key="FR"></country>
</address>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Herent, Paul" sort="Herent, Paul" uniqKey="Herent P" first="Paul" last="Herent">Paul Herent</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Devilder, Matthieu" sort="Devilder, Matthieu" uniqKey="Devilder M" first="Matthieu" last="Devilder">Matthieu Devilder</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-312432" status="VALID"> <orgName>AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)</orgName>
<desc> <address> <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
<country key="FR"></country>
</address>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Soliman, Samer" sort="Soliman, Samer" uniqKey="Soliman S" first="Samer" last="Soliman">Samer Soliman</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-312432" status="VALID"> <orgName>AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)</orgName>
<desc> <address> <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
<country key="FR"></country>
</address>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Meyrignac, Olivier" sort="Meyrignac, Olivier" uniqKey="Meyrignac O" first="Olivier" last="Meyrignac">Olivier Meyrignac</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-312432" status="VALID"> <orgName>AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)</orgName>
<desc> <address> <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
<country key="FR"></country>
</address>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Talabard, Marie Pauline" sort="Talabard, Marie Pauline" uniqKey="Talabard M" first="Marie-Pauline" last="Talabard">Marie-Pauline Talabard</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-312432" status="VALID"> <orgName>AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)</orgName>
<desc> <address> <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
<country key="FR"></country>
</address>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Lamarque, Jean Philippe" sort="Lamarque, Jean Philippe" uniqKey="Lamarque J" first="Jean-Philippe" last="Lamarque">Jean-Philippe Lamarque</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Dubois, Remy" sort="Dubois, Remy" uniqKey="Dubois R" first="Rémy" last="Dubois">Rémy Dubois</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Loiseau, Nicolas" sort="Loiseau, Nicolas" uniqKey="Loiseau N" first="Nicolas" last="Loiseau">Nicolas Loiseau</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Trichelair, Paul" sort="Trichelair, Paul" uniqKey="Trichelair P" first="Paul" last="Trichelair">Paul Trichelair</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Bendjebbar, Etienne" sort="Bendjebbar, Etienne" uniqKey="Bendjebbar E" first="Etienne" last="Bendjebbar">Etienne Bendjebbar</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Garcia, Gabriel" sort="Garcia, Gabriel" uniqKey="Garcia G" first="Gabriel" last="Garcia">Gabriel Garcia</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-456741" status="VALID"> <orgName>Département d'imagerie médicale [Gustave Roussy]</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-156104" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-156104" type="direct"><org type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Balleyguier, Corinne" sort="Balleyguier, Corinne" uniqKey="Balleyguier C" first="Corinne" last="Balleyguier">Corinne Balleyguier</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Merad, Mansouria" sort="Merad, Mansouria" uniqKey="Merad M" first="Mansouria" last="Merad">Mansouria Merad</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Stoclin, Annabelle" sort="Stoclin, Annabelle" uniqKey="Stoclin A" first="Annabelle" last="Stoclin">Annabelle Stoclin</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Jegou, Simon" sort="Jegou, Simon" uniqKey="Jegou S" first="Simon" last="Jegou">Simon Jegou</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Griscelli, Franck" sort="Griscelli, Franck" uniqKey="Griscelli F" first="Franck" last="Griscelli">Franck Griscelli</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Tetelboum, Nicolas" sort="Tetelboum, Nicolas" uniqKey="Tetelboum N" first="Nicolas" last="Tetelboum">Nicolas Tetelboum</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-456741" status="VALID"> <orgName>Département d'imagerie médicale [Gustave Roussy]</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-156104" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-156104" type="direct"><org type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Li, Yingping" sort="Li, Yingping" uniqKey="Li Y" first="Yingping" last="Li">Yingping Li</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Verma, Sagar" sort="Verma, Sagar" uniqKey="Verma S" first="Sagar" last="Verma">Sagar Verma</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Terris, Matthieu" sort="Terris, Matthieu" uniqKey="Terris M" first="Matthieu" last="Terris">Matthieu Terris</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Dardouri, Tasnim" sort="Dardouri, Tasnim" uniqKey="Dardouri T" first="Tasnim" last="Dardouri">Tasnim Dardouri</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Gupta, Kavya" sort="Gupta, Kavya" uniqKey="Gupta K" first="Kavya" last="Gupta">Kavya Gupta</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Neacsu, Ana" sort="Neacsu, Ana" uniqKey="Neacsu A" first="Ana" last="Neacsu">Ana Neacsu</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Chemouni, Frank" sort="Chemouni, Frank" uniqKey="Chemouni F" first="Frank" last="Chemouni">Frank Chemouni</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Sefta, Meriem" sort="Sefta, Meriem" uniqKey="Sefta M" first="Meriem" last="Sefta">Meriem Sefta</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Jehanno, Paul" sort="Jehanno, Paul" uniqKey="Jehanno P" first="Paul" last="Jehanno">Paul Jehanno</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Bousaid, Imad" sort="Bousaid, Imad" uniqKey="Bousaid I" first="Imad" last="Bousaid">Imad Bousaid</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Boursin, Yannick" sort="Boursin, Yannick" uniqKey="Boursin Y" first="Yannick" last="Boursin">Yannick Boursin</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Planchet, Emmanuel" sort="Planchet, Emmanuel" uniqKey="Planchet E" first="Emmanuel" last="Planchet">Emmanuel Planchet</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Azoulay, Mikael" sort="Azoulay, Mikael" uniqKey="Azoulay M" first="Mikael" last="Azoulay">Mikael Azoulay</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Dachary, Jocelyn" sort="Dachary, Jocelyn" uniqKey="Dachary J" first="Jocelyn" last="Dachary">Jocelyn Dachary</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Brulport, Fabien" sort="Brulport, Fabien" uniqKey="Brulport F" first="Fabien" last="Brulport">Fabien Brulport</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Gonzalez, Adrian" sort="Gonzalez, Adrian" uniqKey="Gonzalez A" first="Adrián" last="González">Adrián González</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Dehaene, Olivier" sort="Dehaene, Olivier" uniqKey="Dehaene O" first="Olivier" last="Dehaene">Olivier Dehaene</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Schiratti, Jean Baptiste" sort="Schiratti, Jean Baptiste" uniqKey="Schiratti J" first="Jean-Baptiste" last="Schiratti">Jean-Baptiste Schiratti</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Schutte, Kathryn" sort="Schutte, Kathryn" uniqKey="Schutte K" first="Kathryn" last="Schutte">Kathryn Schutte</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Pesquet, Jean Christophe" sort="Pesquet, Jean Christophe" uniqKey="Pesquet J" first="Jean-Christophe" last="Pesquet">Jean-Christophe Pesquet</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Talbot, Hugues" sort="Talbot, Hugues" uniqKey="Talbot H" first="Hugues" last="Talbot">Hugues Talbot</name>
<affiliation wicri:level="1"><hal:affiliation type="researchteam" xml:id="struct-563293" status="VALID"> <idno type="RNSR">201923238F</idno>
<orgName>OPtimisation Imagerie et Santé</orgName>
<orgName type="acronym">OPIS</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.inria.fr/equipes/opis</ref>
</desc>
<listRelation> <relation active="#struct-118511" type="direct"></relation>
<relation active="#struct-300009" type="indirect"></relation>
<relation active="#struct-187174" type="direct"></relation>
<relation active="#struct-411575" type="indirect"></relation>
</listRelation>
<tutelles><tutelle active="#struct-118511" type="direct"><org type="laboratory" xml:id="struct-118511" status="VALID"> <idno type="RNSR">200818248E</idno>
<orgName>Inria Saclay - Ile de France</orgName>
<desc> <address> <addrLine>1 rue Honoré d'Estienne d'OrvesBâtiment Alan TuringCampus de l'École Polytechnique91120 Palaiseau</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/centre/saclay</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300009" type="indirect"><org type="institution" xml:id="struct-300009" status="VALID"> <orgName>Institut National de Recherche en Informatique et en Automatique</orgName>
<orgName type="acronym">Inria</orgName>
<desc> <address> <addrLine>Domaine de VoluceauRocquencourt - BP 10578153 Le Chesnay Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inria.fr/en/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-187174" type="direct"><org type="laboratory" xml:id="struct-187174" status="VALID"> <idno type="IdRef">183525272</idno>
<orgName>Centre de vision numérique</orgName>
<orgName type="acronym">CVN</orgName>
<desc> <address> <addrLine>CentraleSupélec - Bâtiment Bouygues - 3 rue Joliot Curie - 91190 GIF-SUR-YVETTE</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://cvn.centralesupelec.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300009" type="direct"></relation>
<relation active="#struct-411575" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-411575" type="indirect"><org type="institution" xml:id="struct-411575" status="VALID"> <idno type="IdRef">184443237</idno>
<orgName>CentraleSupélec</orgName>
<desc> <address> <addrLine>3, rue Joliot Curie,Plateau de Moulon,91192 GIF-SUR-YVETTE Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.centralesupelec.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Pronier, Elodie" sort="Pronier, Elodie" uniqKey="Pronier E" first="Elodie" last="Pronier">Elodie Pronier</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Wainrib, Gilles" sort="Wainrib, Gilles" uniqKey="Wainrib G" first="Gilles" last="Wainrib">Gilles Wainrib</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Clozel, Thomas" sort="Clozel, Thomas" uniqKey="Clozel T" first="Thomas" last="Clozel">Thomas Clozel</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Barlesi, Fabrice" sort="Barlesi, Fabrice" uniqKey="Barlesi F" first="Fabrice" last="Barlesi">Fabrice Barlesi</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-156104" status="VALID"> <orgName>Institut Gustave Roussy</orgName>
<orgName type="acronym">IGR</orgName>
<desc> <address> <addrLine>114, rue Édouard-Vaillant 94805 Villejuif Cedex -France</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.gustaveroussy.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Bellin, Marie France" sort="Bellin, Marie France" uniqKey="Bellin M" first="Marie-France" last="Bellin">Marie-France Bellin</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-578126" status="VALID"> <orgName>Unité BioMaps</orgName>
<orgName type="acronym">BIOMAPS</orgName>
<date type="start">2020-01-01</date>
<desc> <address> <addrLine>CEA - Service Hospitalier Frédéric Joliot . 4, place du Général Leclerc 91401 Orsay Cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"></relation>
<relation name="DRF/JOLIOT" active="#struct-465913" type="indirect"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="indirect"></relation>
</listRelation>
<tutelles><tutelle name="DRF/JOLIOT/SHFJ" active="#struct-40418" type="direct"><org type="laboratory" xml:id="struct-40418" status="VALID"> <idno type="RNSR">201722555X</idno>
<orgName>Service Hospitalier Frédéric Joliot</orgName>
<orgName type="acronym">SHFJ</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="DRF/JOLIOT" active="#struct-465913" type="direct"></relation>
<relation active="#struct-300016" type="indirect"></relation>
<relation active="#struct-419361" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle name="DRF/JOLIOT" active="#struct-465913" type="indirect"><org type="regrouplaboratory" xml:id="struct-465913" status="VALID"> <idno type="RNSR">201622496M</idno>
<orgName>Direction de Recherche Fondamentale (CEA)</orgName>
<orgName type="acronym">DRF (CEA)</orgName>
<date type="start">2016-01-01</date>
<desc> <address> <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://ceasciences.fr/</ref>
</desc>
<listRelation> <relation active="#struct-300016" type="direct"></relation>
</listRelation>
</org>
</tutelle>
<tutelle active="#struct-300016" type="indirect"><org type="institution" xml:id="struct-300016" status="VALID"> <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
<orgName type="acronym">CEA</orgName>
<desc> <address> <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.cea.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-419361" type="indirect"><org type="institution" xml:id="struct-419361" status="VALID"> <orgName>Université Paris-Saclay</orgName>
<desc> <address> <addrLine>Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.universite-paris-saclay.fr/fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Blum, Michael" sort="Blum, Michael" uniqKey="Blum M" first="Michael" last="Blum">Michael Blum</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-548107" status="VALID"> <orgName>Owkin France</orgName>
<desc> <address> <addrLine>75 Rue de Turbigo, 75003 Paris</addrLine>
<country key="US"></country>
</address>
<ref type="url">https://owkin.com/</ref>
</desc>
</hal:affiliation>
<country>États-Unis</country>
</affiliation>
</author>
</analytic>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"> <p>With 15% of severe cases among hospitalized patients, the SARS-COV-2 pandemic has put tremendous pressure on Intensive Care Units, and made the identification of early predictors of future severity a public health priority. We collected clinical and biological data, as well as CT scan images and radiology reports from 1,003 coronavirus-infected patients from two French hospitals. Radiologists' manual CT annotations were also available. We first identified 11 clinical variables and 3 types of radiologist-reported features significantly associated with prognosis. Next, focusing on the CT images, we trained deep learning models to automatically segment the scans and reproduce radiologists' annotations. We also built CT image-based deep learning models that predicted future severity better than models based on the radiologists' scan reports. Finally, we showed that including CT scan features alongside the clinical and biological data yielded more accurate predictions than using clinical and biological data alone. These findings show that CT scans provide insightful early predictors of future severity.</p>
</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000023 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 000023 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= PandemieGrippaleV1 |flux= Main |étape= Merge |type= RBID |clé= Hal:hal-02586111 |texte= AI-based multi-modal integration of clinical characteristics, lab tests and chest CTs improves COVID-19 outcome prediction of hospitalized patients }}
![]() | This area was generated with Dilib version V0.6.34. | ![]() |