PandemieGrippaleV1, Main, Exploration, bibRecordById, pubmed:26383585

1918 pandemic influenza virus and Streptococcus pneumoniae co‐infection results in activation of coagulation and widespread pulmonary thrombosis in mice and humans

Identifieur interne : 000A20 ( Main/Exploration ); précédent : 000A19; suivant : 000A21

1918 pandemic influenza virus and Streptococcus pneumoniae co‐infection results in activation of coagulation and widespread pulmonary thrombosis in mice and humans

Auteurs : Kathie-Anne Walters [États-Unis] ; Felice D'Agnillo [États-Unis] ; Zong-Mei Sheng [États-Unis] ; Jason Kindrachuk [États-Unis] ; Louis M. Schwartzman [États-Unis] ; Rolf E. Kuestner [États-Unis] ; Daniel S. Chertow [États-Unis] ; Basil T. Golding [États-Unis] ; Jeffery K. Taubenberger [États-Unis] ; John C. Kash [États-Unis]

Source :

The Journal of Pathology [ 0022-3417 ] ; 2016-01.

RBID : ISTEX:4C548F5BB3A7535ABCBF0447BCE8050DFD3CA12E

Descripteurs français

English descriptors

Abstract

To study bacterial co‐infection following 1918 H1N1 influenza virus infection, mice were inoculated with the 1918 influenza virus, followed by Streptococcus pneumoniae (SP) 72 h later. Co‐infected mice exhibited markedly more severe disease, shortened survival time and more severe lung pathology, including widespread thrombi. Transcriptional profiling revealed activation of coagulation only in co‐infected mice, consistent with the extensive thrombogenesis observed. Immunohistochemistry showed extensive expression of tissue factor (F3) and prominent deposition of neutrophil elastase on endothelial and epithelial cells in co‐infected mice. Lung sections of SP‐positive 1918 autopsy cases showed extensive thrombi and prominent staining for F3 in alveolar macrophages, monocytes, neutrophils, endothelial and epithelial cells, in contrast to co‐infection‐positive 2009 pandemic H1N1 autopsy cases. This study reveals that a distinctive feature of 1918 influenza virus and SP co‐infection in mice and humans is extensive expression of tissue factor and activation of the extrinsic coagulation pathway leading to widespread pulmonary thrombosis. Copyright © 2015 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

Url:

https://api.istex.fr/ark:/67375/WNG-W642W3HK-K/fulltext.pdf

DOI: 10.1002/path.4638

Affiliations:

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">1918 pandemic influenza virus and Streptococcus pneumoniae co‐infection results in activation of coagulation and widespread pulmonary thrombosis in mice and humans</title>
<author><name sortKey="Walters, Kathie Nne" sort="Walters, Kathie Nne" uniqKey="Walters K" first="Kathie-Anne" last="Walters">Kathie-Anne Walters</name>
</author>
<author><name sortKey="D Agnillo, Felice" sort="D Agnillo, Felice" uniqKey="D Agnillo F" first="Felice" last="D'Agnillo">Felice D'Agnillo</name>
</author>
<author><name sortKey="Sheng, Zong Ei" sort="Sheng, Zong Ei" uniqKey="Sheng Z" first="Zong-Mei" last="Sheng">Zong-Mei Sheng</name>
</author>
<author><name sortKey="Kindrachuk, Jason" sort="Kindrachuk, Jason" uniqKey="Kindrachuk J" first="Jason" last="Kindrachuk">Jason Kindrachuk</name>
</author>
<author><name sortKey="Schwartzman, Louis M" sort="Schwartzman, Louis M" uniqKey="Schwartzman L" first="Louis M" last="Schwartzman">Louis M. Schwartzman</name>
</author>
<author><name sortKey="Kuestner, Rolf E" sort="Kuestner, Rolf E" uniqKey="Kuestner R" first="Rolf E" last="Kuestner">Rolf E. Kuestner</name>
</author>
<author><name sortKey="Chertow, Daniel S" sort="Chertow, Daniel S" uniqKey="Chertow D" first="Daniel S" last="Chertow">Daniel S. Chertow</name>
</author>
<author><name sortKey="Golding, Basil T" sort="Golding, Basil T" uniqKey="Golding B" first="Basil T" last="Golding">Basil T. Golding</name>
</author>
<author><name sortKey="Taubenberger, Jeffery K" sort="Taubenberger, Jeffery K" uniqKey="Taubenberger J" first="Jeffery K" last="Taubenberger">Jeffery K. Taubenberger</name>
</author>
<author><name sortKey="Kash, John C" sort="Kash, John C" uniqKey="Kash J" first="John C" last="Kash">John C. Kash</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:4C548F5BB3A7535ABCBF0447BCE8050DFD3CA12E</idno>
<date when="2016" year="2016">2016</date>
<idno type="doi">10.1002/path.4638</idno>
<idno type="url">https://api.istex.fr/ark:/67375/WNG-W642W3HK-K/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000488</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000488</idno>
<idno type="wicri:Area/Istex/Curation">000488</idno>
<idno type="wicri:Area/Istex/Checkpoint">000104</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000104</idno>
<idno type="wicri:doubleKey">0022-3417:2016:Walters K:pandemic:influenza:virus</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:26383585</idno>
<idno type="wicri:Area/PubMed/Corpus">000603</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000603</idno>
<idno type="wicri:Area/PubMed/Curation">000603</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000603</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000543</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000543</idno>
<idno type="wicri:Area/Ncbi/Merge">001A85</idno>
<idno type="wicri:Area/Ncbi/Curation">001A85</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001A85</idno>
<idno type="wicri:Area/Main/Merge">000A23</idno>
<idno type="wicri:Area/Main/Curation">000A20</idno>
<idno type="wicri:Area/Main/Exploration">000A20</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main">1918 pandemic influenza virus and Streptococcus pneumoniae co‐infection results in activation of coagulation and widespread pulmonary thrombosis in mice and humans</title>
<author><name sortKey="Walters, Kathie Nne" sort="Walters, Kathie Nne" uniqKey="Walters K" first="Kathie-Anne" last="Walters">Kathie-Anne Walters</name>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Institute for Systems Biology, WA, Seattle</wicri:regionArea>
<wicri:noRegion>Seattle</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="D Agnillo, Felice" sort="D Agnillo, Felice" uniqKey="D Agnillo F" first="Felice" last="D'Agnillo">Felice D'Agnillo</name>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Laboratory of Biochemistry and Vascular Biology, Division of Hematology Research and Review, Center for Biologics Evaluation and Research, Office of Blood Research and Review, Food and Drug Administration, MD, Silver Spring</wicri:regionArea>
<wicri:noRegion>Silver Spring</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sheng, Zong Ei" sort="Sheng, Zong Ei" uniqKey="Sheng Z" first="Zong-Mei" last="Sheng">Zong-Mei Sheng</name>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), MD, 20892, NIH, Bethesda</wicri:regionArea>
<wicri:noRegion>Bethesda</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kindrachuk, Jason" sort="Kindrachuk, Jason" uniqKey="Kindrachuk J" first="Jason" last="Kindrachuk">Jason Kindrachuk</name>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Critical Care Medicine Department, National Institutes of Health (NIH), MD, Bethesda</wicri:regionArea>
<wicri:noRegion>Bethesda</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schwartzman, Louis M" sort="Schwartzman, Louis M" uniqKey="Schwartzman L" first="Louis M" last="Schwartzman">Louis M. Schwartzman</name>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), MD, 20892, NIH, Bethesda</wicri:regionArea>
<wicri:noRegion>Bethesda</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kuestner, Rolf E" sort="Kuestner, Rolf E" uniqKey="Kuestner R" first="Rolf E" last="Kuestner">Rolf E. Kuestner</name>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Institute for Systems Biology, WA, Seattle</wicri:regionArea>
<wicri:noRegion>Seattle</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chertow, Daniel S" sort="Chertow, Daniel S" uniqKey="Chertow D" first="Daniel S" last="Chertow">Daniel S. Chertow</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Critical Care Medicine Department, National Institutes of Health (NIH), Bethesda, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), MD, 20892, NIH, Bethesda</wicri:regionArea>
<wicri:noRegion>Bethesda</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Golding, Basil T" sort="Golding, Basil T" uniqKey="Golding B" first="Basil T" last="Golding">Basil T. Golding</name>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Laboratory of Biochemistry and Vascular Biology, Division of Hematology Research and Review, Center for Biologics Evaluation and Research, Office of Blood Research and Review, Food and Drug Administration, MD, Silver Spring</wicri:regionArea>
<wicri:noRegion>Silver Spring</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Taubenberger, Jeffery K" sort="Taubenberger, Jeffery K" uniqKey="Taubenberger J" first="Jeffery K" last="Taubenberger">Jeffery K. Taubenberger</name>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), MD, 20892, NIH, Bethesda</wicri:regionArea>
<wicri:noRegion>Bethesda</wicri:noRegion>
</affiliation>
<affiliation></affiliation>
</author>
<author><name sortKey="Kash, John C" sort="Kash, John C" uniqKey="Kash J" first="John C" last="Kash">John C. Kash</name>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), MD, 20892, NIH, Bethesda</wicri:regionArea>
<wicri:noRegion>Bethesda</wicri:noRegion>
</affiliation>
<affiliation></affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">The Journal of Pathology</title>
<title level="j" type="alt">THE JOURNAL OF PATHOLOGY</title>
<idno type="ISSN">0022-3417</idno>
<idno type="eISSN">1096-9896</idno>
<imprint><biblScope unit="vol">238</biblScope>
<biblScope unit="issue">1</biblScope>
<biblScope unit="page" from="85">85</biblScope>
<biblScope unit="page" to="97">97</biblScope>
<biblScope unit="page-count">13</biblScope>
<publisher>John Wiley & Sons, Ltd</publisher>
<pubPlace>Chichester, UK</pubPlace>
<date type="published" when="2016-01">2016-01</date>
</imprint>
<idno type="ISSN">0022-3417</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0022-3417</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Blood Coagulation</term>
<term>Coinfection (complications)</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Humans</term>
<term>Immunohistochemistry</term>
<term>Influenza A Virus, H1N1 Subtype</term>
<term>Influenza Pandemic, 1918-1919</term>
<term>Influenza, Human (complications)</term>
<term>Influenza, Human (microbiology)</term>
<term>Influenza, Human (pathology)</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Oligonucleotide Array Sequence Analysis</term>
<term>Orthomyxoviridae Infections (complications)</term>
<term>Orthomyxoviridae Infections (microbiology)</term>
<term>Orthomyxoviridae Infections (pathology)</term>
<term>Pneumococcal Infections (complications)</term>
<term>Pneumococcal Infections (microbiology)</term>
<term>Pneumococcal Infections (pathology)</term>
<term>Pulmonary Embolism (microbiology)</term>
<term>Pulmonary Embolism (pathology)</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
<term>Streptococcus pneumoniae</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Co-infection ()</term>
<term>Coagulation sanguine</term>
<term>Embolie pulmonaire (anatomopathologie)</term>
<term>Embolie pulmonaire (microbiologie)</term>
<term>Femelle</term>
<term>Grippe humaine ()</term>
<term>Grippe humaine (anatomopathologie)</term>
<term>Grippe humaine (microbiologie)</term>
<term>Humains</term>
<term>Immunohistochimie</term>
<term>Infections à Orthomyxoviridae ()</term>
<term>Infections à Orthomyxoviridae (anatomopathologie)</term>
<term>Infections à Orthomyxoviridae (microbiologie)</term>
<term>Infections à pneumocoques ()</term>
<term>Infections à pneumocoques (anatomopathologie)</term>
<term>Infections à pneumocoques (microbiologie)</term>
<term>Modèles animaux de maladie humaine</term>
<term>Pandémie de grippe de 1918-1919</term>
<term>RT-PCR</term>
<term>Souris</term>
<term>Souris de lignée BALB C</term>
<term>Sous-type H1N1 du virus de la grippe A</term>
<term>Streptococcus pneumoniae</term>
<term>Séquençage par oligonucléotides en batterie</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Embolie pulmonaire</term>
<term>Grippe humaine</term>
<term>Infections à Orthomyxoviridae</term>
<term>Infections à pneumocoques</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coinfection</term>
<term>Influenza, Human</term>
<term>Orthomyxoviridae Infections</term>
<term>Pneumococcal Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Embolie pulmonaire</term>
<term>Grippe humaine</term>
<term>Infections à Orthomyxoviridae</term>
<term>Infections à pneumocoques</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Influenza, Human</term>
<term>Orthomyxoviridae Infections</term>
<term>Pneumococcal Infections</term>
<term>Pulmonary Embolism</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Influenza, Human</term>
<term>Orthomyxoviridae Infections</term>
<term>Pneumococcal Infections</term>
<term>Pulmonary Embolism</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Blood Coagulation</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Humans</term>
<term>Immunohistochemistry</term>
<term>Influenza A Virus, H1N1 Subtype</term>
<term>Influenza Pandemic, 1918-1919</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Oligonucleotide Array Sequence Analysis</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
<term>Streptococcus pneumoniae</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Co-infection</term>
<term>Coagulation sanguine</term>
<term>Femelle</term>
<term>Grippe humaine</term>
<term>Humains</term>
<term>Immunohistochimie</term>
<term>Infections à Orthomyxoviridae</term>
<term>Infections à pneumocoques</term>
<term>Modèles animaux de maladie humaine</term>
<term>Pandémie de grippe de 1918-1919</term>
<term>RT-PCR</term>
<term>Souris</term>
<term>Souris de lignée BALB C</term>
<term>Sous-type H1N1 du virus de la grippe A</term>
<term>Streptococcus pneumoniae</term>
<term>Séquençage par oligonucléotides en batterie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract">To study bacterial co‐infection following 1918 H1N1 influenza virus infection, mice were inoculated with the 1918 influenza virus, followed by Streptococcus pneumoniae (SP) 72 h later. Co‐infected mice exhibited markedly more severe disease, shortened survival time and more severe lung pathology, including widespread thrombi. Transcriptional profiling revealed activation of coagulation only in co‐infected mice, consistent with the extensive thrombogenesis observed. Immunohistochemistry showed extensive expression of tissue factor (F3) and prominent deposition of neutrophil elastase on endothelial and epithelial cells in co‐infected mice. Lung sections of SP‐positive 1918 autopsy cases showed extensive thrombi and prominent staining for F3 in alveolar macrophages, monocytes, neutrophils, endothelial and epithelial cells, in contrast to co‐infection‐positive 2009 pandemic H1N1 autopsy cases. This study reveals that a distinctive feature of 1918 influenza virus and SP co‐infection in mice and humans is extensive expression of tissue factor and activation of the extrinsic coagulation pathway leading to widespread pulmonary thrombosis. Copyright © 2015 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Maryland</li>
</region>
</list>
<tree><country name="États-Unis"><noRegion><name sortKey="Walters, Kathie Nne" sort="Walters, Kathie Nne" uniqKey="Walters K" first="Kathie-Anne" last="Walters">Kathie-Anne Walters</name>
</noRegion>
<name sortKey="Chertow, Daniel S" sort="Chertow, Daniel S" uniqKey="Chertow D" first="Daniel S" last="Chertow">Daniel S. Chertow</name>
<name sortKey="Chertow, Daniel S" sort="Chertow, Daniel S" uniqKey="Chertow D" first="Daniel S" last="Chertow">Daniel S. Chertow</name>
<name sortKey="D Agnillo, Felice" sort="D Agnillo, Felice" uniqKey="D Agnillo F" first="Felice" last="D'Agnillo">Felice D'Agnillo</name>
<name sortKey="Golding, Basil T" sort="Golding, Basil T" uniqKey="Golding B" first="Basil T" last="Golding">Basil T. Golding</name>
<name sortKey="Kash, John C" sort="Kash, John C" uniqKey="Kash J" first="John C" last="Kash">John C. Kash</name>
<name sortKey="Kindrachuk, Jason" sort="Kindrachuk, Jason" uniqKey="Kindrachuk J" first="Jason" last="Kindrachuk">Jason Kindrachuk</name>
<name sortKey="Kuestner, Rolf E" sort="Kuestner, Rolf E" uniqKey="Kuestner R" first="Rolf E" last="Kuestner">Rolf E. Kuestner</name>
<name sortKey="Schwartzman, Louis M" sort="Schwartzman, Louis M" uniqKey="Schwartzman L" first="Louis M" last="Schwartzman">Louis M. Schwartzman</name>
<name sortKey="Sheng, Zong Ei" sort="Sheng, Zong Ei" uniqKey="Sheng Z" first="Zong-Mei" last="Sheng">Zong-Mei Sheng</name>
<name sortKey="Taubenberger, Jeffery K" sort="Taubenberger, Jeffery K" uniqKey="Taubenberger J" first="Jeffery K" last="Taubenberger">Jeffery K. Taubenberger</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A20 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000A20 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    PandemieGrippaleV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:4C548F5BB3A7535ABCBF0447BCE8050DFD3CA12E
   |texte=   1918 pandemic influenza virus and Streptococcus pneumoniae co‐infection results in activation of coagulation and widespread pulmonary thrombosis in mice and humans
}}

This area was generated with Dilib version V0.6.34.
Data generation: Wed Jun 10 11:04:28 2020. Site generation: Sun Mar 28 09:10:28 2021

Serveur d'exploration sur les pandémies grippales

1918 pandemic influenza virus and Streptococcus pneumoniae co‐infection results in activation of coagulation and widespread pulmonary thrombosis in mice and humans

1918 pandemic influenza virus and Streptococcus pneumoniae co‐infection results in activation of coagulation and widespread pulmonary thrombosis in mice and humans

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration sur les pandémies grippales
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.