ADVANCES IN THE NEUROBIOLOGY OF OBSESSIVE-COMPULSIVE DISORDER
Identifieur interne : 005B58 ( Main/Exploration ); précédent : 005B57; suivant : 005B59ADVANCES IN THE NEUROBIOLOGY OF OBSESSIVE-COMPULSIVE DISORDER
Auteurs : Dan J. SteinSource :
- Psychiatric Clinics of North America [ 0193-953X ] ; 2000.
English descriptors
- Teeft :
- Abnormality, Acad child adolesc psychiatry, Acute administration, Anxiety disorders, Autistic disorder, Autoimmune mechanisms, Basal, Basal ganglia, Basal ganglia abnormalities, Basal ganglia circuits, Basal ganglia dysfunction, Basal ganglia involvement, Basal ganglia volume, Basal ganglia volumes, Behavioral responses, Biol, Biol psychiatry, Brain regions, Canine acral, Cerebral blood flow, Child psycho1 psychiatry, Clin, Clin psychiatry, Clomipramine, Compensatory response, Compr psychiatry, Corticostriatal circuits, Crucial role, Desipramine, Disorder, Dopamine, Dysfunction, Family studies, Family study, Frontal, Frontal activity, Frontal areas, Frontal lesions, Functional studies, Ganglion, Genetic factors, Genetic relationship, Glucose metabolism, Healthy controls, Hollander, Hyperactivity disorder, Imaging, Imaging studies, Impulsive, Impulsive aggression, Impulsive symptoms, Inhibitor, Leckman, Locomotory stereotypies, Lymphocyte antigen, Major depression, Many questions, Mcpp, Medical research council unit, Monozygotic twins, Neurobiology, Neurochemical systems, Neuroendocrine response, Neuroendocrine responses, Neuropsychological studies, Noradrenergic reuptake inhibitors, Obsessive, Obsessivecompulsive, Obsessivecompulsive disorder, Other disorders, Other hand, Preliminary evidence, Procedural strategies, Psychiatric annals, Psychiatry, Psychopharmacol bull, Putative spectrum disorders, Rapoport, Raven press, Receptor, Receptor locus, Repetitive behaviors, Reuptake, Selective efficacy, Serotonergic, Serotonergic function, Serotonergic responsivity, Serotonin, Several disorders, Spectrum disorders, Sris, Streptococcal infection, Streptococcal infections, Such patients, Swedo, Symptom, Syndrome, Tourette syndrome, Trichotillomania.
Abstract
For many decades, obsessive-compulsive disorder (OCD) was considered one of the exemplars of a psychogenic condition.88 In the past 20 years, however, data about the neurobiological underpinnings of OCD have steadily accumulated. Interest in OCD also has encouraged work on a hypothesized spectrum of related disorders that are characterized by an overlapping phenomenology and psychobiology.25,38,64,86,111 Nevertheless, the question of how best to delineate this spectrum remains unanswered,82 perhaps partly because the underlying mechanisms of OCD and putative spectrum disorders remain incompletely understood. This article reviews current advances in the neurochemistry, neuroanatomy, neurogenetics, neuroimmunology, and neuroethology of OCD and then uses this information to consider different approaches toward the concept of an obsessive-compulsive spectrum and its neurobiology.
Url:
DOI: 10.1016/S0193-953X(05)70180-5
Affiliations:
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Interest in OCD also has encouraged work on a hypothesized spectrum of related disorders that are characterized by an overlapping phenomenology and psychobiology.25,38,64,86,111 Nevertheless, the question of how best to delineate this spectrum remains unanswered,82 perhaps partly because the underlying mechanisms of OCD and putative spectrum disorders remain incompletely understood. This article reviews current advances in the neurochemistry, neuroanatomy, neurogenetics, neuroimmunology, and neuroethology of OCD and then uses this information to consider different approaches toward the concept of an obsessive-compulsive spectrum and its neurobiology.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Stein, Dan J" sort="Stein, Dan J" uniqKey="Stein D" first="Dan J." last="Stein">Dan J. Stein</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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