Seasonal Influenza Vaccination during Pregnancy and the Risks of Preterm Delivery and Small for Gestational Age Birth
Identifieur interne : 000F28 ( Main/Exploration ); précédent : 000F27; suivant : 000F29Seasonal Influenza Vaccination during Pregnancy and the Risks of Preterm Delivery and Small for Gestational Age Birth
Auteurs : Katherine A. Ahrens [États-Unis] ; Carol Louik [États-Unis] ; Stephen Kerr [États-Unis] ; Allen A. Mitchell [États-Unis] ; Martha M. Werler [États-Unis]Source :
- Paediatric and Perinatal Epidemiology [ 0269-5022 ] ; 2014-11.
Abstract
Background: Influenza vaccination is routinely recommended for pregnant women, yet information on perinatal outcomes is sparse. Methods: We investigated the associations between trivalent (seasonal) influenza vaccination during pregnancy and the risks of preterm delivery (PTD, live birth <37 weeks gestation) and small for gestational age birth (SGA, <10th percentile in weight for sex‐specific gestational age) during the influenza seasons 2006–07 through 2009–10. The study population included 1619 mothers of live‐born, non‐malformed singleton infants interviewed as part of the Slone Epidemiology Center's Birth Defects Study. Associations between influenza vaccination and PTD and SGA were assessed using Cox and logistic regression models, respectively, with propensity scores used to adjust for confounding. Women vaccinated against pandemic H1N1 were excluded from the analysis. Results: Influenza vaccination during pregnancy showed a near null association with PTD for influenza seasons 2006–07 through 2008–09 compared with unvaccinated women [adjusted hazard ratios (aHR) ranged from 0.79 [95% confidence interval (CI) 0.28, 2.21] in 2007–08 to 1.08 [95% CI: 0.40, 2.95] in 2008–09]. For 2009–10, the risk of PTD was higher in vaccinated women (aHR, 7.81 [95% CI: 2.66, 23.0]). Influenza vaccination was not associated with appreciable risks for SGA for all seasons with sufficient numbers of exposed SGA. Conclusion: Though limited by study size, these findings add support to previous observations of little or no increased risk of PTD or SGA associated with seasonal influenza vaccination for three of the four influenza seasons in our study. The increased risk of PTD observed for the 2009–10 influenza season warrants further investigation.
Url:
DOI: 10.1111/ppe.12152
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001E26
- to stream Istex, to step Curation: 001E26
- to stream Istex, to step Checkpoint: 000217
- to stream Main, to step Merge: 000F35
- to stream Main, to step Curation: 000F28
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Seasonal Influenza Vaccination during Pregnancy and the Risks of Preterm Delivery and Small for Gestational Age Birth</title><author><name sortKey="Ahrens, Katherine A" sort="Ahrens, Katherine A" uniqKey="Ahrens K" first="Katherine A." last="Ahrens">Katherine A. Ahrens</name></author><author><name sortKey="Louik, Carol" sort="Louik, Carol" uniqKey="Louik C" first="Carol" last="Louik">Carol Louik</name></author><author><name sortKey="Kerr, Stephen" sort="Kerr, Stephen" uniqKey="Kerr S" first="Stephen" last="Kerr">Stephen Kerr</name></author><author><name sortKey="Mitchell, Allen A" sort="Mitchell, Allen A" uniqKey="Mitchell A" first="Allen A." last="Mitchell">Allen A. Mitchell</name></author><author><name sortKey="Werler, Martha M" sort="Werler, Martha M" uniqKey="Werler M" first="Martha M." last="Werler">Martha M. Werler</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:9251FB44B4FDC4A4A52ACAEC84B61D84C4A163B0</idno><date when="2014" year="2014">2014</date><idno type="doi">10.1111/ppe.12152</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-M1FHL5M2-1/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001E26</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001E26</idno><idno type="wicri:Area/Istex/Curation">001E26</idno><idno type="wicri:Area/Istex/Checkpoint">000217</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000217</idno><idno type="wicri:doubleKey">0269-5022:2014:Ahrens K:seasonal:influenza:vaccination</idno><idno type="wicri:Area/Main/Merge">000F35</idno><idno type="wicri:Area/Main/Curation">000F28</idno><idno type="wicri:Area/Main/Exploration">000F28</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Seasonal Influenza Vaccination during Pregnancy and the Risks of Preterm Delivery and Small for Gestational Age Birth</title><author><name sortKey="Ahrens, Katherine A" sort="Ahrens, Katherine A" uniqKey="Ahrens K" first="Katherine A." last="Ahrens">Katherine A. Ahrens</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Slone Epidemiology Center, Boston University, Boston</wicri:cityArea></affiliation><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Epidemiology Department, School of Public Health, Boston University, MA</wicri:orgArea></affiliation></author><author><name sortKey="Louik, Carol" sort="Louik, Carol" uniqKey="Louik C" first="Carol" last="Louik">Carol Louik</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Slone Epidemiology Center, Boston University, Boston</wicri:cityArea></affiliation><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Epidemiology Department, School of Public Health, Boston University, MA</wicri:orgArea></affiliation></author><author><name sortKey="Kerr, Stephen" sort="Kerr, Stephen" uniqKey="Kerr S" first="Stephen" last="Kerr">Stephen Kerr</name><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Slone Epidemiology Center, Boston University, MA</wicri:orgArea></affiliation></author><author><name sortKey="Mitchell, Allen A" sort="Mitchell, Allen A" uniqKey="Mitchell A" first="Allen A." last="Mitchell">Allen A. Mitchell</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Slone Epidemiology Center, Boston University, Boston</wicri:cityArea></affiliation><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Epidemiology Department, School of Public Health, Boston University, MA</wicri:orgArea></affiliation></author><author><name sortKey="Werler, Martha M" sort="Werler, Martha M" uniqKey="Werler M" first="Martha M." last="Werler">Martha M. Werler</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Slone Epidemiology Center, Boston University, Boston</wicri:cityArea></affiliation><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Epidemiology Department, School of Public Health, Boston University, MA</wicri:orgArea></affiliation><affiliation></affiliation><affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Paediatric and Perinatal Epidemiology</title><title level="j" type="alt">PAEDIATRIC AND PERINATAL EPIDEMIOLOGY</title><idno type="ISSN">0269-5022</idno><idno type="eISSN">1365-3016</idno><imprint><biblScope unit="vol">28</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="498">498</biblScope><biblScope unit="page" to="509">509</biblScope><biblScope unit="page-count">12</biblScope><date type="published" when="2014-11">2014-11</date></imprint><idno type="ISSN">0269-5022</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0269-5022</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">Background: Influenza vaccination is routinely recommended for pregnant women, yet information on perinatal outcomes is sparse. Methods: We investigated the associations between trivalent (seasonal) influenza vaccination during pregnancy and the risks of preterm delivery (PTD, live birth <37 weeks gestation) and small for gestational age birth (SGA, <10th percentile in weight for sex‐specific gestational age) during the influenza seasons 2006–07 through 2009–10. The study population included 1619 mothers of live‐born, non‐malformed singleton infants interviewed as part of the Slone Epidemiology Center's Birth Defects Study. Associations between influenza vaccination and PTD and SGA were assessed using Cox and logistic regression models, respectively, with propensity scores used to adjust for confounding. Women vaccinated against pandemic H1N1 were excluded from the analysis. Results: Influenza vaccination during pregnancy showed a near null association with PTD for influenza seasons 2006–07 through 2008–09 compared with unvaccinated women [adjusted hazard ratios (aHR) ranged from 0.79 [95% confidence interval (CI) 0.28, 2.21] in 2007–08 to 1.08 [95% CI: 0.40, 2.95] in 2008–09]. For 2009–10, the risk of PTD was higher in vaccinated women (aHR, 7.81 [95% CI: 2.66, 23.0]). Influenza vaccination was not associated with appreciable risks for SGA for all seasons with sufficient numbers of exposed SGA. Conclusion: Though limited by study size, these findings add support to previous observations of little or no increased risk of PTD or SGA associated with seasonal influenza vaccination for three of the four influenza seasons in our study. The increased risk of PTD observed for the 2009–10 influenza season warrants further investigation.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Massachusetts</li></region><settlement><li>Boston</li></settlement></list><tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Ahrens, Katherine A" sort="Ahrens, Katherine A" uniqKey="Ahrens K" first="Katherine A." last="Ahrens">Katherine A. Ahrens</name></region><name sortKey="Ahrens, Katherine A" sort="Ahrens, Katherine A" uniqKey="Ahrens K" first="Katherine A." last="Ahrens">Katherine A. Ahrens</name><name sortKey="Kerr, Stephen" sort="Kerr, Stephen" uniqKey="Kerr S" first="Stephen" last="Kerr">Stephen Kerr</name><name sortKey="Louik, Carol" sort="Louik, Carol" uniqKey="Louik C" first="Carol" last="Louik">Carol Louik</name><name sortKey="Louik, Carol" sort="Louik, Carol" uniqKey="Louik C" first="Carol" last="Louik">Carol Louik</name><name sortKey="Mitchell, Allen A" sort="Mitchell, Allen A" uniqKey="Mitchell A" first="Allen A." last="Mitchell">Allen A. Mitchell</name><name sortKey="Mitchell, Allen A" sort="Mitchell, Allen A" uniqKey="Mitchell A" first="Allen A." last="Mitchell">Allen A. Mitchell</name><name sortKey="Werler, Martha M" sort="Werler, Martha M" uniqKey="Werler M" first="Martha M." last="Werler">Martha M. Werler</name><name sortKey="Werler, Martha M" sort="Werler, Martha M" uniqKey="Werler M" first="Martha M." last="Werler">Martha M. Werler</name><name sortKey="Werler, Martha M" sort="Werler, Martha M" uniqKey="Werler M" first="Martha M." last="Werler">Martha M. Werler</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F28 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000F28 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= PandemieGrippaleV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:9251FB44B4FDC4A4A52ACAEC84B61D84C4A163B0
|texte= Seasonal Influenza Vaccination during Pregnancy and the Risks of Preterm Delivery and Small for Gestational Age Birth
}}
| This area was generated with Dilib version V0.6.34. |  |