Mitochondrial diversity of Iñupiat people from the Alaskan North Slope provides evidence for the origins of the Paleo‐ and Neo‐Eskimo peoples
Identifieur interne : 000988 ( Istex/Curation ); précédent : 000987; suivant : 000989Mitochondrial diversity of Iñupiat people from the Alaskan North Slope provides evidence for the origins of the Paleo‐ and Neo‐Eskimo peoples
Auteurs : Jennifer A. Raff [États-Unis] ; Margarita Rzhetskaya [États-Unis] ; Justin Tackney ; M. Geoffrey Hayes [États-Unis]Source :
- American Journal of Physical Anthropology [ 0002-9483 ] ; 2015-08.
Abstract
Objectives:: All modern Iñupiaq speakers share a common origin, the result of a recent (∼800 YBP) and rapid trans‐Arctic migration by the Neo‐Eskimo Thule, who replaced the previous Paleo‐Eskimo inhabitants of the region. Reduced mitochondrial haplogroup diversity in the eastern Arctic supports the archaeological hypothesis that the migration occurred in an eastward direction. We tested the hypothesis that the Alaskan North Slope served as the origin of the Neo‐ and Paleo‐Eskimo populations further east. Materials and Methods:: We sequenced HVR I and HVR II of the mitochondrial D‐loop from 151 individuals in eight Alaska North Slope communities, and compared genetic diversity and phylogenetic relationships between the North Slope Inupiat and other Arctic populations from Siberia, the Aleutian Islands, Canada, and Greenland. Results:: Mitochondrial lineages from the North Slope villages had a low frequency (2%) of non‐Arctic maternal admixture, and all haplogroups (A2, A2a, A2b, D2a, and D4b1a–formerly known as D3) found in previously sequenced Neo‐ and Paleo‐Eskimos and living Inuit and Eskimo peoples from across the North American Arctic. Lineages basal for each haplogroup were present in the North Slope. We also found the first occurrence of two haplogroups in contemporary North American Arctic populations: D2a, previously identified only in Aleuts and Paleo‐Eskimos, and the pan‐American C4. Discussion:: Our results yield insight into the maternal population history of the Alaskan North Slope and support the hypothesis that this region served as an ancestral pool for eastward movements to Canada and Greenland, for both the Paleo‐Eskimo and Neo‐Eskimo populations. Am J Phys Anthropol 157:603–614, 2015. © 2015 Wiley Periodicals, Inc.
Url:
DOI: 10.1002/ajpa.22750
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000988
Links to Exploration step
ISTEX:9F212EC388DD58A31710560F5C8EBE03EC714F3ACuration
No country items
Justin Tackney<affiliation><mods:affiliation>Department of Anthropology, University of Utah, UT, 84112, Salt Lake City</mods:affiliation>
<wicri:noCountry code="subField">City</wicri:noCountry>
</affiliation>
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mitochondrial diversity of Iñupiat people from the Alaskan North Slope provides evidence for the origins of the Paleo‐ and Neo‐Eskimo peoples</title>
<author><name sortKey="Raff, Jennifer A" sort="Raff, Jennifer A" uniqKey="Raff J" first="Jennifer A." last="Raff">Jennifer A. Raff</name>
<affiliation wicri:level="3"><mods:affiliation>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, IL, 60611, Chicago</mods:affiliation>
<country>États-Unis</country>
<placeName><settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
<wicri:orgArea>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, IL, 60611</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Rzhetskaya, Margarita" sort="Rzhetskaya, Margarita" uniqKey="Rzhetskaya M" first="Margarita" last="Rzhetskaya">Margarita Rzhetskaya</name>
<affiliation wicri:level="3"><mods:affiliation>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, IL, 60611, Chicago</mods:affiliation>
<country>États-Unis</country>
<placeName><settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
<wicri:orgArea>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, IL, 60611</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Tackney, Justin" sort="Tackney, Justin" uniqKey="Tackney J" first="Justin" last="Tackney">Justin Tackney</name>
<affiliation><mods:affiliation>Department of Anthropology, University of Utah, UT, 84112, Salt Lake City</mods:affiliation>
<wicri:noCountry code="subField">City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Hayes, M Geoffrey" sort="Hayes, M Geoffrey" uniqKey="Hayes M" first="M. Geoffrey" last="Hayes">M. Geoffrey Hayes</name>
<affiliation wicri:level="2"><mods:affiliation>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 60611, Chicago, IL</mods:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Illinois</region>
</placeName>
<wicri:cityArea>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 60611, Chicago</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><mods:affiliation>Department of Anthropology, Northwestern University, 60208, Evanston, IL</mods:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Illinois</region>
</placeName>
<wicri:cityArea>Department of Anthropology, Northwestern University, 60208, Evanston</wicri:cityArea>
</affiliation>
<affiliation wicri:level="3"><mods:affiliation>Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, IL, 60611, Chicago</mods:affiliation>
<country>États-Unis</country>
<placeName><settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
<wicri:orgArea>Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, IL, 60611</wicri:orgArea>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>E-mail: ghayes@northwestern.edu</mods:affiliation>
<country wicri:rule="url">États-Unis</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:9F212EC388DD58A31710560F5C8EBE03EC714F3A</idno>
<date when="2015" year="2015">2015</date>
<idno type="doi">10.1002/ajpa.22750</idno>
<idno type="url">https://api.istex.fr/ark:/67375/WNG-BMNFXT2X-4/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000988</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000988</idno>
<idno type="wicri:Area/Istex/Curation">000988</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main">Mitochondrial diversity of Iñupiat people from the Alaskan North Slope provides evidence for the origins of the Paleo‐ and Neo‐Eskimo peoples</title>
<author><name sortKey="Raff, Jennifer A" sort="Raff, Jennifer A" uniqKey="Raff J" first="Jennifer A." last="Raff">Jennifer A. Raff</name>
<affiliation wicri:level="3"><mods:affiliation>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, IL, 60611, Chicago</mods:affiliation>
<country>États-Unis</country>
<placeName><settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
<wicri:orgArea>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, IL, 60611</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Rzhetskaya, Margarita" sort="Rzhetskaya, Margarita" uniqKey="Rzhetskaya M" first="Margarita" last="Rzhetskaya">Margarita Rzhetskaya</name>
<affiliation wicri:level="3"><mods:affiliation>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, IL, 60611, Chicago</mods:affiliation>
<country>États-Unis</country>
<placeName><settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
<wicri:orgArea>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, IL, 60611</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Tackney, Justin" sort="Tackney, Justin" uniqKey="Tackney J" first="Justin" last="Tackney">Justin Tackney</name>
<affiliation><mods:affiliation>Department of Anthropology, University of Utah, UT, 84112, Salt Lake City</mods:affiliation>
<wicri:noCountry code="subField">City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Hayes, M Geoffrey" sort="Hayes, M Geoffrey" uniqKey="Hayes M" first="M. Geoffrey" last="Hayes">M. Geoffrey Hayes</name>
<affiliation wicri:level="2"><mods:affiliation>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 60611, Chicago, IL</mods:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Illinois</region>
</placeName>
<wicri:cityArea>Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 60611, Chicago</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><mods:affiliation>Department of Anthropology, Northwestern University, 60208, Evanston, IL</mods:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Illinois</region>
</placeName>
<wicri:cityArea>Department of Anthropology, Northwestern University, 60208, Evanston</wicri:cityArea>
</affiliation>
<affiliation wicri:level="3"><mods:affiliation>Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, IL, 60611, Chicago</mods:affiliation>
<country>États-Unis</country>
<placeName><settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
<wicri:orgArea>Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, IL, 60611</wicri:orgArea>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>E-mail: ghayes@northwestern.edu</mods:affiliation>
<country wicri:rule="url">États-Unis</country>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">American Journal of Physical Anthropology</title>
<title level="j" type="alt">AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY</title>
<idno type="ISSN">0002-9483</idno>
<idno type="eISSN">1096-8644</idno>
<imprint><biblScope unit="vol">157</biblScope>
<biblScope unit="issue">4</biblScope>
<biblScope unit="page" from="603">603</biblScope>
<biblScope unit="page" to="614">614</biblScope>
<biblScope unit="page-count">12</biblScope>
<date type="published" when="2015-08">2015-08</date>
</imprint>
<idno type="ISSN">0002-9483</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0002-9483</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract">Objectives:: All modern Iñupiaq speakers share a common origin, the result of a recent (∼800 YBP) and rapid trans‐Arctic migration by the Neo‐Eskimo Thule, who replaced the previous Paleo‐Eskimo inhabitants of the region. Reduced mitochondrial haplogroup diversity in the eastern Arctic supports the archaeological hypothesis that the migration occurred in an eastward direction. We tested the hypothesis that the Alaskan North Slope served as the origin of the Neo‐ and Paleo‐Eskimo populations further east. Materials and Methods:: We sequenced HVR I and HVR II of the mitochondrial D‐loop from 151 individuals in eight Alaska North Slope communities, and compared genetic diversity and phylogenetic relationships between the North Slope Inupiat and other Arctic populations from Siberia, the Aleutian Islands, Canada, and Greenland. Results:: Mitochondrial lineages from the North Slope villages had a low frequency (2%) of non‐Arctic maternal admixture, and all haplogroups (A2, A2a, A2b, D2a, and D4b1a–formerly known as D3) found in previously sequenced Neo‐ and Paleo‐Eskimos and living Inuit and Eskimo peoples from across the North American Arctic. Lineages basal for each haplogroup were present in the North Slope. We also found the first occurrence of two haplogroups in contemporary North American Arctic populations: D2a, previously identified only in Aleuts and Paleo‐Eskimos, and the pan‐American C4. Discussion:: Our results yield insight into the maternal population history of the Alaskan North Slope and support the hypothesis that this region served as an ancestral pool for eastward movements to Canada and Greenland, for both the Paleo‐Eskimo and Neo‐Eskimo populations. Am J Phys Anthropol 157:603–614, 2015. © 2015 Wiley Periodicals, Inc.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000988 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 000988 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= PandemieGrippaleV1 |flux= Istex |étape= Curation |type= RBID |clé= ISTEX:9F212EC388DD58A31710560F5C8EBE03EC714F3A |texte= Mitochondrial diversity of Iñupiat people from the Alaskan North Slope provides evidence for the origins of the Paleo‐ and Neo‐Eskimo peoples }}
![]() | This area was generated with Dilib version V0.6.34. | ![]() |