Plant Natural Products as a Potential Source of Antimicrobial Agents: An Overview and a Glimpse on Recent Developments
Identifieur interne : 001452 ( Istex/Corpus ); précédent : 001451; suivant : 001453Plant Natural Products as a Potential Source of Antimicrobial Agents: An Overview and a Glimpse on Recent Developments
Auteurs : Mohd. Shahid ; Fazal K. Dar ; Abdulrahman Y. Ismaeel ; Ali Al-Mahmeed ; Khalid Al Sindi ; Abida Malik ; Haris M. KhanSource :
Abstract
Abstract: Natural products of plant origin are being used to cure infections since ancient times. However, the real breakthrough in the field of antimicrobial agents was after the advent of a chemical substance produced by a strain of the mold Penicillium, by Alexander Fleming, that he named penicillin in 1928. Since that time, the fungi and higher plants have been searched for antibacterial compounds, including cephalosporins and aminoglycosides. In some of our previous articles published during years 2009–2010 we reviewed the literature on plant natural products harboring the antibacterial and antifungal properties. In this article we will explore the very recent developments in the said field with an emphasis on antibacterial, antifungal, anti-parasitic and antiviral potentials (especially against Human Immunodeficiency virus and Influenza virus) and some of the other interesting recent developments.
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DOI: 10.1007/978-94-007-6603-7_5
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Shahid</name><affiliation><mods:affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Pathology, Blood Bank and Laboratory Medicine, King Hamad University Hospital, Busaiteen, Kingdom of Bahrain</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: shahidsahar@yahoo.co.in</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: mohammeds@agu.edu.bh</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: mohammad.shahid@khuh.org.bh</mods:affiliation></affiliation></author><author><name sortKey="Dar, Fazal K" sort="Dar, Fazal K" uniqKey="Dar F" first="Fazal K." last="Dar">Fazal K. 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Ismaeel</name><affiliation><mods:affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</mods:affiliation></affiliation></author><author><name sortKey="Al Mahmeed, Ali" sort="Al Mahmeed, Ali" uniqKey="Al Mahmeed A" first="Ali" last="Al-Mahmeed">Ali Al-Mahmeed</name><affiliation><mods:affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</mods:affiliation></affiliation></author><author><name sortKey="Sindi, Khalid Al" sort="Sindi, Khalid Al" uniqKey="Sindi K" first="Khalid Al" last="Sindi">Khalid Al Sindi</name><affiliation><mods:affiliation>Department of Pathology, Blood Bank and Laboratory Medicine, King Hamad University Hospital, Busaiteen, Kingdom of Bahrain</mods:affiliation></affiliation></author><author><name sortKey="Malik, Abida" sort="Malik, Abida" uniqKey="Malik A" first="Abida" last="Malik">Abida Malik</name><affiliation><mods:affiliation>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</mods:affiliation></affiliation></author><author><name sortKey="Khan, Haris M" sort="Khan, Haris M" uniqKey="Khan H" first="Haris M." last="Khan">Haris M. 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Shahid</name><affiliation><mods:affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Pathology, Blood Bank and Laboratory Medicine, King Hamad University Hospital, Busaiteen, Kingdom of Bahrain</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: shahidsahar@yahoo.co.in</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: mohammeds@agu.edu.bh</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: mohammad.shahid@khuh.org.bh</mods:affiliation></affiliation></author><author><name sortKey="Dar, Fazal K" sort="Dar, Fazal K" uniqKey="Dar F" first="Fazal K." last="Dar">Fazal K. Dar</name><affiliation><mods:affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</mods:affiliation></affiliation></author><author><name sortKey="Ismaeel, Abdulrahman Y" sort="Ismaeel, Abdulrahman Y" uniqKey="Ismaeel A" first="Abdulrahman Y." last="Ismaeel">Abdulrahman Y. Ismaeel</name><affiliation><mods:affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</mods:affiliation></affiliation></author><author><name sortKey="Al Mahmeed, Ali" sort="Al Mahmeed, Ali" uniqKey="Al Mahmeed A" first="Ali" last="Al-Mahmeed">Ali Al-Mahmeed</name><affiliation><mods:affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</mods:affiliation></affiliation></author><author><name sortKey="Sindi, Khalid Al" sort="Sindi, Khalid Al" uniqKey="Sindi K" first="Khalid Al" last="Sindi">Khalid Al Sindi</name><affiliation><mods:affiliation>Department of Pathology, Blood Bank and Laboratory Medicine, King Hamad University Hospital, Busaiteen, Kingdom of Bahrain</mods:affiliation></affiliation></author><author><name sortKey="Malik, Abida" sort="Malik, Abida" uniqKey="Malik A" first="Abida" last="Malik">Abida Malik</name><affiliation><mods:affiliation>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</mods:affiliation></affiliation></author><author><name sortKey="Khan, Haris M" sort="Khan, Haris M" uniqKey="Khan H" first="Haris M." last="Khan">Haris M. Khan</name><affiliation><mods:affiliation>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</mods:affiliation></affiliation></author></analytic><monogr></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Natural products of plant origin are being used to cure infections since ancient times. However, the real breakthrough in the field of antimicrobial agents was after the advent of a chemical substance produced by a strain of the mold Penicillium, by Alexander Fleming, that he named penicillin in 1928. Since that time, the fungi and higher plants have been searched for antibacterial compounds, including cephalosporins and aminoglycosides. In some of our previous articles published during years 2009–2010 we reviewed the literature on plant natural products harboring the antibacterial and antifungal properties. In this article we will explore the very recent developments in the said field with an emphasis on antibacterial, antifungal, anti-parasitic and antiviral potentials (especially against Human Immunodeficiency virus and Influenza virus) and some of the other interesting recent developments.</div></front></TEI><istex><corpusName>springer-ebooks</corpusName><editor><json:item><name>Mohd. Shahid</name><affiliations><json:string>Arabian Gulf University, Department Of Medical Microbiology, College of Medicine & Medical Sciences, Manama, Bahrain</json:string><json:string>E-mail: shahidsahar@yahoo.co.in</json:string></affiliations></json:item><json:item><name>Anwar Shahzad</name><affiliations><json:string>, Department of Botany, Aligarh Muslim University, 202002, Aligarh, Uttar Pradesh, India</json:string><json:string>E-mail: ashahzad.bt@amu.ac.in</json:string></affiliations></json:item><json:item><name>Abida Malik</name><affiliations><json:string>, Department of Microbiology, Aligarh Muslim University, J. N. Medical College & Hospital, 202002, Aligarh, Uttar Pradesh, India</json:string><json:string>E-mail: abidamalik2k@yahoo.com</json:string></affiliations></json:item><json:item><name>Aastha Sahai</name><affiliations><json:string>, Department of Botany, Aligarh Muslim University, 202002, Aligarh, Uttar Pradesh, India</json:string><json:string>E-mail: aasthasahai@rediffmail.com</json:string></affiliations></json:item></editor><author><json:item><name>Mohd. Shahid M.B.B.S., M.D., Ph.D., FNZIMLS</name><affiliations><json:string>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</json:string><json:string>Department of Pathology, Blood Bank and Laboratory Medicine, King Hamad University Hospital, Busaiteen, Kingdom of Bahrain</json:string><json:string>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</json:string><json:string>E-mail: shahidsahar@yahoo.co.in</json:string><json:string>E-mail: mohammeds@agu.edu.bh</json:string><json:string>E-mail: mohammad.shahid@khuh.org.bh</json:string></affiliations></json:item><json:item><name>Fazal K. Dar</name><affiliations><json:string>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</json:string></affiliations></json:item><json:item><name>Abdulrahman Y. Ismaeel</name><affiliations><json:string>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</json:string></affiliations></json:item><json:item><name>Ali Al-Mahmeed</name><affiliations><json:string>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</json:string></affiliations></json:item><json:item><name>Khalid Al Sindi</name><affiliations><json:string>Department of Pathology, Blood Bank and Laboratory Medicine, King Hamad University Hospital, Busaiteen, Kingdom of Bahrain</json:string></affiliations></json:item><json:item><name>Abida Malik</name><affiliations><json:string>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</json:string></affiliations></json:item><json:item><name>Haris M. Khan</name><affiliations><json:string>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</json:string></affiliations></json:item></author><arkIstex>ark:/67375/HCB-2RK65TH1-Q</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>chapter</json:string></originalGenre><abstract>Abstract: Natural products of plant origin are being used to cure infections since ancient times. However, the real breakthrough in the field of antimicrobial agents was after the advent of a chemical substance produced by a strain of the mold Penicillium, by Alexander Fleming, that he named penicillin in 1928. Since that time, the fungi and higher plants have been searched for antibacterial compounds, including cephalosporins and aminoglycosides. In some of our previous articles published during years 2009–2010 we reviewed the literature on plant natural products harboring the antibacterial and antifungal properties. In this article we will explore the very recent developments in the said field with an emphasis on antibacterial, antifungal, anti-parasitic and antiviral potentials (especially against Human Immunodeficiency virus and Influenza virus) and some of the other interesting recent developments.</abstract><qualityIndicators><score>8.464</score><pdfWordCount>4880</pdfWordCount><pdfCharCount>34338</pdfCharCount><pdfVersion>1.4</pdfVersion><pdfPageCount>15</pdfPageCount><pdfPageSize>439.37 x 666.14 pts</pdfPageSize><refBibsNative>false</refBibsNative><abstractWordCount>132</abstractWordCount><abstractCharCount>916</abstractCharCount><keywordCount>0</keywordCount></qualityIndicators><title>Plant Natural Products as a Potential Source of Antimicrobial Agents: An Overview and a Glimpse on Recent Developments</title><chapterId><json:string>5</json:string><json:string>b978-94-007-6603-7_5</json:string></chapterId><genre><json:string>chapter</json:string></genre><host><title>Recent Trends in Biotechnology and Therapeutic Applications of Medicinal Plants</title><language><json:string>unknown</json:string></language><copyrightDate>2013</copyrightDate><doi><json:string>10.1007/978-94-007-6603-7</json:string></doi><eisbn><json:string>978-94-007-6603-7</json:string></eisbn><bookId><json:string>978-94-007-6603-7</json:string></bookId><isbn><json:string>978-94-007-6602-0</json:string></isbn><pages><first>93</first><last>107</last></pages><genre><json:string>book</json:string></genre><editor><json:item><name>Mohd. Shahid</name><affiliations><json:string>Arabian Gulf University, Department Of Medical Microbiology, College of Medicine & Medical Sciences, Manama, Bahrain</json:string><json:string>E-mail: shahidsahar@yahoo.co.in</json:string></affiliations></json:item><json:item><name>Anwar Shahzad</name><affiliations><json:string>, Department of Botany, Aligarh Muslim University, 202002, Aligarh, Uttar Pradesh, India</json:string><json:string>E-mail: ashahzad.bt@amu.ac.in</json:string></affiliations></json:item><json:item><name>Abida Malik</name><affiliations><json:string>, Department of Microbiology, Aligarh Muslim University, J. N. Medical College & Hospital, 202002, Aligarh, Uttar Pradesh, India</json:string><json:string>E-mail: abidamalik2k@yahoo.com</json:string></affiliations></json:item><json:item><name>Aastha Sahai</name><affiliations><json:string>, Department of Botany, Aligarh Muslim University, 202002, Aligarh, Uttar Pradesh, India</json:string><json:string>E-mail: aasthasahai@rediffmail.com</json:string></affiliations></json:item></editor><subject><json:item><value>Chemistry and Materials Science</value></json:item><json:item><value>Chemistry</value></json:item><json:item><value>Biotechnology</value></json:item><json:item><value>Plant Breeding/Biotechnology</value></json:item><json:item><value>Pharmaceutical Sciences/Technology</value></json:item><json:item><value>Primary Care Medicine</value></json:item><json:item><value>Conservation Biology/Ecology</value></json:item><json:item><value>Popular Science in Medicine and 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type="first">Ali</forename><surname>Al-Mahmeed</surname></persName><affiliation><orgName type="department">Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences</orgName><orgName type="institution">Arabian Gulf University</orgName><address><postBox>26671</postBox><settlement>Manama</settlement><country key=""></country></address></affiliation></author><author><persName><forename type="first">Khalid</forename><forename type="first">Al</forename><surname>Sindi</surname></persName><affiliation><orgName type="department">Department of Pathology, Blood Bank and Laboratory Medicine</orgName><orgName type="institution">King Hamad University Hospital</orgName><address><settlement>Busaiteen</settlement><country key=""></country></address></affiliation></author><author><persName><forename type="first">Abida</forename><surname>Malik</surname></persName><affiliation><orgName type="department">Department of Microbiology, Jawaharlal Nehru 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type="DOI">10.1007/978-94-007-6603-7</idno><idno type="book-id">978-94-007-6603-7</idno><idno type="ISBN">978-94-007-6602-0</idno><idno type="eISBN">978-94-007-6603-7</idno><idno type="chapter-id">b978-94-007-6603-7_5</idno><editor><persName><forename type="first">Mohd.</forename><surname>Shahid</surname></persName><email>shahidsahar@yahoo.co.in</email><affiliation><orgName type="department">Arabian Gulf University, Department Of Medical Microbiology</orgName><orgName type="institution">College of Medicine & Medical Sciences</orgName><address><settlement>Manama</settlement><country key="BH">BAHRAIN</country></address></affiliation></editor><editor><persName><forename type="first">Anwar</forename><surname>Shahzad</surname></persName><email>ashahzad.bt@amu.ac.in</email><affiliation><orgName type="department">, Department of Botany</orgName><orgName type="institution">Aligarh Muslim University</orgName><address><settlement>Aligarh</settlement><postCode>202002</postCode><region>Uttar Pradesh</region><country key="IN">INDIA</country></address></affiliation></editor><editor><persName><forename type="first">Abida</forename><surname>Malik</surname></persName><email>abidamalik2k@yahoo.com</email><affiliation><orgName type="department">, Department of Microbiology</orgName><orgName type="institution">Aligarh Muslim University</orgName><address><street>J. N. Medical College & Hospital</street><settlement>Aligarh</settlement><postCode>202002</postCode><region>Uttar Pradesh</region><country key="IN">INDIA</country></address></affiliation></editor><editor><persName><forename type="first">Aastha</forename><surname>Sahai</surname></persName><email>aasthasahai@rediffmail.com</email><affiliation><orgName type="department">, Department of Botany</orgName><orgName type="institution">Aligarh Muslim University</orgName><address><settlement>Aligarh</settlement><postCode>202002</postCode><region>Uttar Pradesh</region><country key="IN">INDIA</country></address></affiliation></editor><imprint><biblScope unit="page" from="93">93</biblScope><biblScope unit="page" to="107">107</biblScope><biblScope unit="chapter-count">15</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en"><head>Abstract</head><p>Natural products of plant origin are being used to cure infections since ancient times. However, the real breakthrough in the field of antimicrobial agents was after the advent of a chemical substance produced by a strain of the mold <hi rend="italic">Penicillium</hi>, by Alexander Fleming, that he named penicillin in 1928. Since that time, the fungi and higher plants have been searched for antibacterial compounds, including cephalosporins and aminoglycosides. In some of our previous articles published during years 2009–2010 we reviewed the literature on plant natural products harboring the antibacterial and antifungal properties. In this article we will explore the very recent developments in the said field with an emphasis on antibacterial, antifungal, anti-parasitic and antiviral potentials (especially against Human Immunodeficiency virus and Influenza virus) and some of the other interesting recent developments.</p></abstract><textClass ana="subject"><keywords scheme="book-subject-collection"><list><label>SUCO11644</label><item><term>Chemistry and Materials Science</term></item></list></keywords></textClass><textClass ana="subject"><keywords scheme="book-subject"><list><label>SCC</label><item><term type="Primary">Chemistry</term></item><label>SCC12002</label><item><term type="Secondary" subtype="priority-1">Biotechnology</term></item><label>SCL24060</label><item><term type="Secondary" subtype="priority-2">Plant Breeding/Biotechnology</term></item><label>SCB21010</label><item><term type="Secondary" subtype="priority-3">Pharmaceutical Sciences/Technology</term></item><label>SCH51000</label><item><term 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name="istex:docType"></istex:docType><istex:document><Publisher><PublisherInfo><PublisherName>Springer Netherlands</PublisherName><PublisherLocation>Dordrecht</PublisherLocation><PublisherImprintName>Springer</PublisherImprintName></PublisherInfo><Book Language="En" OutputMedium="All"><BookInfo BookProductType="Contributed volume" ContainsESM="No" Language="En" MediaType="eBook" NumberingDepth="3" NumberingStyle="ChapterContent" OutputMedium="All" TocLevels="0"><BookID>978-94-007-6603-7</BookID><BookTitle>Recent Trends in Biotechnology and Therapeutic Applications of Medicinal Plants</BookTitle><BookDOI>10.1007/978-94-007-6603-7</BookDOI><BookTitleID>307860</BookTitleID><BookPrintISBN>978-94-007-6602-0</BookPrintISBN><BookElectronicISBN>978-94-007-6603-7</BookElectronicISBN><BookEdition>2013</BookEdition><BookChapterCount>15</BookChapterCount><BookCopyright><CopyrightHolderName>Springer Science+Business Media Dordrecht</CopyrightHolderName><CopyrightYear>2013</CopyrightYear></BookCopyright><BookSubjectGroup><BookSubject Code="SCC" Type="Primary">Chemistry</BookSubject><BookSubject Code="SCC12002" Priority="1" Type="Secondary">Biotechnology</BookSubject><BookSubject Code="SCL24060" Priority="2" Type="Secondary">Plant Breeding/Biotechnology</BookSubject><BookSubject Code="SCB21010" Priority="3" Type="Secondary">Pharmaceutical Sciences/Technology</BookSubject><BookSubject Code="SCH51000" Priority="4" Type="Secondary">Primary Care Medicine</BookSubject><BookSubject Code="SCL19150" Priority="5" Type="Secondary">Conservation Biology/Ecology</BookSubject><BookSubject Code="SCQ14008" Priority="6" Type="Secondary">Popular Science in Medicine and Health</BookSubject><SubjectCollection Code="SUCO11644">Chemistry and Materials Science</SubjectCollection></BookSubjectGroup><BookstoreLocation>Chemistry</BookstoreLocation></BookInfo><BookHeader><EditorGroup><Editor AffiliationIDS="Aff54"><EditorName DisplayOrder="Western"><GivenName>Mohd.</GivenName><FamilyName>Shahid</FamilyName></EditorName><Contact><Phone>+973-36402742</Phone><Email>shahidsahar@yahoo.co.in</Email></Contact></Editor><Editor AffiliationIDS="Aff55"><EditorName DisplayOrder="Western"><GivenName>Anwar</GivenName><FamilyName>Shahzad</FamilyName></EditorName><Contact><Email>ashahzad.bt@amu.ac.in</Email></Contact></Editor><Editor AffiliationIDS="Aff56"><EditorName DisplayOrder="Western"><GivenName>Abida</GivenName><FamilyName>Malik</FamilyName></EditorName><Contact><Email>abidamalik2k@yahoo.com</Email></Contact></Editor><Editor AffiliationIDS="Aff57"><EditorName DisplayOrder="Western"><GivenName>Aastha</GivenName><FamilyName>Sahai</FamilyName></EditorName><Contact><Email>aasthasahai@rediffmail.com</Email></Contact></Editor><Affiliation ID="Aff54"><OrgDivision>Arabian Gulf University, Department Of Medical Microbiology</OrgDivision><OrgName>College of Medicine & Medical Sciences</OrgName><OrgAddress><City>Manama</City><Country>Bahrain</Country></OrgAddress></Affiliation><Affiliation ID="Aff55"><OrgDivision>, Department of Botany</OrgDivision><OrgName>Aligarh Muslim University</OrgName><OrgAddress><City>Aligarh</City><Postcode>202002</Postcode><State>Uttar Pradesh</State><Country>India</Country></OrgAddress></Affiliation><Affiliation ID="Aff56"><OrgDivision>, Department of Microbiology</OrgDivision><OrgName>Aligarh Muslim University</OrgName><OrgAddress><Street>J. N. Medical College & Hospital</Street><City>Aligarh</City><Postcode>202002</Postcode><State>Uttar Pradesh</State><Country>India</Country></OrgAddress></Affiliation><Affiliation ID="Aff57"><OrgDivision>, Department of Botany</OrgDivision><OrgName>Aligarh Muslim University</OrgName><OrgAddress><City>Aligarh</City><Postcode>202002</Postcode><State>Uttar Pradesh</State><Country>India</Country></OrgAddress></Affiliation></EditorGroup></BookHeader><Chapter ID="b978-94-007-6603-7_5" Language="En" OutputMedium="All"><ChapterInfo ChapterType="OriginalPaper" ContainsESM="No" Language="En" NumberingDepth="3" NumberingStyle="ChapterContent" OutputMedium="All" TocLevels="0"><ChapterID>5</ChapterID><ChapterNumber>Chapter 5</ChapterNumber><ChapterDOI>10.1007/978-94-007-6603-7_5</ChapterDOI><ChapterSequenceNumber>5</ChapterSequenceNumber><ChapterTitle Language="En">Plant Natural Products as a Potential Source of Antimicrobial Agents: An Overview and a Glimpse on Recent Developments</ChapterTitle><ChapterFirstPage>93</ChapterFirstPage><ChapterLastPage>107</ChapterLastPage><ChapterCopyright><CopyrightHolderName>Springer Science+Business Media Dordrecht</CopyrightHolderName><CopyrightYear>2013</CopyrightYear></ChapterCopyright><ChapterHistory><RegistrationDate><Year>2013</Year><Month>2</Month><Day>19</Day></RegistrationDate><OnlineDate><Year>2013</Year><Month>4</Month><Day>15</Day></OnlineDate></ChapterHistory><ChapterContext><BookID>978-94-007-6603-7</BookID><BookTitle>Recent Trends in Biotechnology and Therapeutic Applications of Medicinal Plants</BookTitle></ChapterContext></ChapterInfo><ChapterHeader><AuthorGroup><Author AffiliationIDS="Aff00051 Aff00052 Aff00053" CorrespondingAffiliationID="Aff00051"><AuthorName DisplayOrder="Western"><GivenName>Mohd.</GivenName><FamilyName>Shahid</FamilyName><Degrees>M.B.B.S., M.D., Ph.D., FNZIMLS</Degrees></AuthorName><Contact><Email>shahidsahar@yahoo.co.in</Email><Email>mohammeds@agu.edu.bh</Email><Email>mohammad.shahid@khuh.org.bh</Email></Contact></Author><Author AffiliationIDS="Aff00051"><AuthorName DisplayOrder="Western"><GivenName>Fazal</GivenName><GivenName>K.</GivenName><FamilyName>Dar</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff00051"><AuthorName DisplayOrder="Western"><GivenName>Abdulrahman</GivenName><GivenName>Y.</GivenName><FamilyName>Ismaeel</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff00051"><AuthorName DisplayOrder="Western"><GivenName>Ali</GivenName><FamilyName>Al-Mahmeed</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff00052"><AuthorName DisplayOrder="Western"><GivenName>Khalid</GivenName><GivenName>Al</GivenName><FamilyName>Sindi</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff00053"><AuthorName DisplayOrder="Western"><GivenName>Abida</GivenName><FamilyName>Malik</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff00053"><AuthorName DisplayOrder="Western"><GivenName>Haris</GivenName><GivenName>M.</GivenName><FamilyName>Khan</FamilyName></AuthorName></Author><Affiliation ID="Aff00051"><OrgDivision>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences</OrgDivision><OrgName>Arabian Gulf University</OrgName><OrgAddress><Postbox>26671</Postbox><City>Manama</City><Country>Kingdom of Bahrain</Country></OrgAddress></Affiliation><Affiliation ID="Aff00052"><OrgDivision>Department of Pathology, Blood Bank and Laboratory Medicine</OrgDivision><OrgName>King Hamad University Hospital</OrgName><OrgAddress><City>Busaiteen</City><Country>Kingdom of Bahrain</Country></OrgAddress></Affiliation><Affiliation ID="Aff00053"><OrgDivision>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital</OrgDivision><OrgName>Aligarh Muslim University</OrgName><OrgAddress><City>Aligarh</City><State>Uttar Pradesh</State><Country>India</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs00051" Language="En" OutputMedium="Online"><Heading>Abstract</Heading><Para>Natural products of plant origin are being used to cure infections since ancient times. However, the real breakthrough in the field of antimicrobial agents was after the advent of a chemical substance produced by a strain of the mold <Emphasis Type="Italic">Penicillium</Emphasis>, by Alexander Fleming, that he named penicillin in 1928. Since that time, the fungi and higher plants have been searched for antibacterial compounds, including cephalosporins and aminoglycosides. In some of our previous articles published during years 2009–2010 we reviewed the literature on plant natural products harboring the antibacterial and antifungal properties. In this article we will explore the very recent developments in the said field with an emphasis on antibacterial, antifungal, anti-parasitic and antiviral potentials (especially against Human Immunodeficiency virus and Influenza virus) and some of the other interesting recent developments.</Para></Abstract></ChapterHeader><NoBody></NoBody></Chapter></Book></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Plant Natural Products as a Potential Source of Antimicrobial Agents: An Overview and a Glimpse on Recent Developments</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Plant Natural Products as a Potential Source of Antimicrobial Agents: An Overview and a Glimpse on Recent Developments</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">Mohd.</namePart><namePart type="family">Shahid</namePart><namePart type="termsOfAddress">M.B.B.S., M.D., Ph.D., FNZIMLS</namePart><affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</affiliation><affiliation>Department of Pathology, Blood Bank and Laboratory Medicine, King Hamad University Hospital, Busaiteen, Kingdom of Bahrain</affiliation><affiliation>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</affiliation><affiliation>E-mail: shahidsahar@yahoo.co.in</affiliation><affiliation>E-mail: mohammeds@agu.edu.bh</affiliation><affiliation>E-mail: mohammad.shahid@khuh.org.bh</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Fazal</namePart><namePart type="given">K.</namePart><namePart type="family">Dar</namePart><affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Abdulrahman</namePart><namePart type="given">Y.</namePart><namePart type="family">Ismaeel</namePart><affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ali</namePart><namePart type="family">Al-Mahmeed</namePart><affiliation>Department of Medical Microbiology, Immunology and Infectious Diseases, College of Medicine and Medical Sciences, Arabian Gulf University, 26671, Manama, Kingdom of Bahrain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Khalid</namePart><namePart type="given">Al</namePart><namePart type="family">Sindi</namePart><affiliation>Department of Pathology, Blood Bank and Laboratory Medicine, King Hamad University Hospital, Busaiteen, Kingdom of Bahrain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Abida</namePart><namePart type="family">Malik</namePart><affiliation>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Haris</namePart><namePart type="given">M.</namePart><namePart type="family">Khan</namePart><affiliation>Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mohd.</namePart><namePart type="family">Shahid</namePart><affiliation>Arabian Gulf University, Department Of Medical Microbiology, College of Medicine & Medical Sciences, Manama, Bahrain</affiliation><affiliation>E-mail: shahidsahar@yahoo.co.in</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Anwar</namePart><namePart type="family">Shahzad</namePart><affiliation>, Department of Botany, Aligarh Muslim University, 202002, Aligarh, Uttar Pradesh, India</affiliation><affiliation>E-mail: ashahzad.bt@amu.ac.in</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Abida</namePart><namePart type="family">Malik</namePart><affiliation>, Department of Microbiology, Aligarh Muslim University, J. N. Medical College & Hospital, 202002, Aligarh, Uttar Pradesh, India</affiliation><affiliation>E-mail: abidamalik2k@yahoo.com</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Aastha</namePart><namePart type="family">Sahai</namePart><affiliation>, Department of Botany, Aligarh Muslim University, 202002, Aligarh, Uttar Pradesh, India</affiliation><affiliation>E-mail: aasthasahai@rediffmail.com</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="chapter" displayLabel="chapter" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-CGT4WMJM-6"></genre><originInfo><publisher>Springer Netherlands</publisher><place><placeTerm type="text">Dordrecht</placeTerm></place><dateIssued encoding="w3cdtf">2013</dateIssued><copyrightDate encoding="w3cdtf">2013</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: Natural products of plant origin are being used to cure infections since ancient times. However, the real breakthrough in the field of antimicrobial agents was after the advent of a chemical substance produced by a strain of the mold Penicillium, by Alexander Fleming, that he named penicillin in 1928. Since that time, the fungi and higher plants have been searched for antibacterial compounds, including cephalosporins and aminoglycosides. In some of our previous articles published during years 2009–2010 we reviewed the literature on plant natural products harboring the antibacterial and antifungal properties. 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