Toward Effective Vaccine Deployment: A Systematic Study
Identifieur interne : 001068 ( Istex/Corpus ); précédent : 001067; suivant : 001069Toward Effective Vaccine Deployment: A Systematic Study
Auteurs : Jiming Liu ; Shang XiaSource :
- Journal of Medical Systems [ 0148-5598 ] ; 2011.
Abstract
Abstract: Vaccination is a commonly-used epidemic control strategy based on direct antiviral immunization and indirect reduction of virus transmissibility. There exist three factors related to the efficacy of vaccine deployment; they are: (1) vaccine coverage, (2) releasing time, and (3) deployment method. Yet, the exact impacts of these factors still remain to be systematically studied. In our work, we examine the effectiveness of vaccination-based epidemic control in adjusting the composition of susceptible and infectious individuals (referred to as composite structure) in a host population. We develop a modified compartmental infection model for characterizing virus spreading dynamics in several age-specific host populations (one host population for each age group). We consider vaccine deployment schedules that correspond to different settings of the three deployment factors. Based on our simulation-based experiments, we evaluate the impacts of deployment factors on virus spreading dynamics as well as their implications for an effective vaccination strategy.
Url:
DOI: 10.1007/s10916-011-9734-x
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ISTEX:2EEAB5D445DB91B4CD5BD7C3C1BA8848ECA805D7Le document en format XML
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CorrespondingAffiliationID="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Jiming</GivenName><FamilyName>Liu</FamilyName></AuthorName><Contact><Email>jiming@comp.hkbu.edu.hk</Email></Contact></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Shang</GivenName><FamilyName>Xia</FamilyName></AuthorName><Contact><Email>sxia@comp.hkbu.edu.hk</Email></Contact></Author><Affiliation ID="Aff1"><OrgDivision>Department of Computer Science</OrgDivision><OrgName>Hong Kong Baptist University</OrgName><OrgAddress><City>Kowloon Tong</City><Country Code="HK">Hong Kong</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading><Para>Vaccination is a commonly-used epidemic control strategy based on direct antiviral immunization and indirect reduction of virus transmissibility. There exist three factors related to the efficacy of vaccine deployment; they are: (1) vaccine coverage, (2) releasing time, and (3) deployment method. Yet, the exact impacts of these factors still remain to be systematically studied. In our work, we examine the effectiveness of vaccination-based epidemic control in adjusting the composition of susceptible and infectious individuals (referred to as composite structure) in a host population. We develop a modified compartmental infection model for characterizing virus spreading dynamics in several age-specific host populations (one host population for each age group). We consider vaccine deployment schedules that correspond to different settings of the three deployment factors. Based on our simulation-based experiments, we evaluate the impacts of deployment factors on virus spreading dynamics as well as their implications for an effective vaccination strategy.</Para></Abstract><KeywordGroup Language="En"><Heading>Keywords</Heading><Keyword>Epidemic control</Keyword><Keyword>H1N1 influenza</Keyword><Keyword>Vaccine deployment strategy</Keyword><Keyword>Age-specific compartmental model</Keyword></KeywordGroup><ArticleNote Type="Misc"><SimplePara>A preliminary version of this paper was presented at the 1st ACM International Health Informatics Symposium (IHI’10), November 11–12, 2010, Arlington, VA, USA.</SimplePara></ArticleNote></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Toward Effective Vaccine Deployment: A Systematic Study</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Toward Effective Vaccine Deployment: A Systematic Study</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">Jiming</namePart><namePart type="family">Liu</namePart><affiliation>Department of Computer Science, Hong Kong Baptist University, Kowloon Tong, Hong Kong</affiliation><affiliation>E-mail: jiming@comp.hkbu.edu.hk</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Shang</namePart><namePart type="family">Xia</namePart><affiliation>Department of Computer Science, Hong Kong Baptist University, Kowloon Tong, Hong Kong</affiliation><affiliation>E-mail: sxia@comp.hkbu.edu.hk</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>Springer US; http://www.springer-ny.com</publisher><place><placeTerm type="text">Boston</placeTerm></place><dateCreated encoding="w3cdtf">2011-01-28</dateCreated><dateIssued encoding="w3cdtf">2011-10-01</dateIssued><copyrightDate encoding="w3cdtf">2011</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: Vaccination is a commonly-used epidemic control strategy based on direct antiviral immunization and indirect reduction of virus transmissibility. There exist three factors related to the efficacy of vaccine deployment; they are: (1) vaccine coverage, (2) releasing time, and (3) deployment method. Yet, the exact impacts of these factors still remain to be systematically studied. In our work, we examine the effectiveness of vaccination-based epidemic control in adjusting the composition of susceptible and infectious individuals (referred to as composite structure) in a host population. We develop a modified compartmental infection model for characterizing virus spreading dynamics in several age-specific host populations (one host population for each age group). We consider vaccine deployment schedules that correspond to different settings of the three deployment factors. Based on our simulation-based experiments, we evaluate the impacts of deployment factors on virus spreading dynamics as well as their implications for an effective vaccination strategy.</abstract><note>Original Paper</note><subject lang="en"><genre>Keywords</genre><topic>Epidemic control</topic><topic>H1N1 influenza</topic><topic>Vaccine deployment strategy</topic><topic>Age-specific compartmental model</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Medical Systems</title></titleInfo><titleInfo type="abbreviated"><title>J Med Syst</title></titleInfo><name type="personal"><namePart type="given">Ali</namePart><namePart type="family">Emrouznejad</namePart><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Prasanta</namePart><namePart type="family">Dey</namePart><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Jasjit</namePart><namePart type="family">Suri</namePart><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Sana</namePart><namePart type="family">Ullah</namePart><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Henrique</namePart><namePart type="family">Andrade</namePart><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Neil</namePart><namePart type="family">Smalheiser</namePart><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Eddie YK</namePart><namePart type="family">Ng</namePart><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Rajendra</namePart><namePart type="family">Achara U</namePart><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Riyi</namePart><namePart type="family">Shi</namePart><role><roleTerm type="text">editor</roleTerm></role></name><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>Springer</publisher><dateIssued encoding="w3cdtf">2011</dateIssued><copyrightDate encoding="w3cdtf">2011</copyrightDate></originInfo><subject><genre>Statistics</genre><topic>Statistics for Life Sciences, Medicine, Health Sciences</topic><topic>Health Informatics</topic></subject><identifier type="ISSN">0148-5598</identifier><identifier type="eISSN">1573-689X</identifier><identifier type="JournalID">10916</identifier><identifier type="IssueArticleCount">57</identifier><identifier type="VolumeIssueCount">6</identifier><part><date>2011</date><detail type="issue"><title>Special Issue on Proceedings of the Second International Conference on Biomedical Engineering and Informatics, Special Issue on Distributed Diagnosis and Home Healthcare, Special Issue on ACM International Health Informatics 2010, Special Issue on Performance Measurement in the Health Sector and Special Issue on Ban on Healthcare Applications</title></detail><detail type="volume"><number>35</number><caption>vol.</caption></detail><detail type="issue"><number>5</number><caption>no.</caption></detail><extent unit="pages"><start>1153</start><end>1164</end></extent></part><recordInfo><recordOrigin>Springer Science+Business Media, LLC, 2011</recordOrigin></recordInfo></relatedItem><identifier type="istex">2EEAB5D445DB91B4CD5BD7C3C1BA8848ECA805D7</identifier><identifier type="ark">ark:/67375/VQC-8Z0M3W4F-H</identifier><identifier type="DOI">10.1007/s10916-011-9734-x</identifier><identifier type="ArticleID">9734</identifier><identifier type="ArticleID">s10916-011-9734-x</identifier><accessCondition type="use and reproduction" contentType="copyright">Springer Science+Business Media, LLC, 2011</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</recordContentSource><recordOrigin>Converted from (version 1.2.14) to MODS version 3.6.</recordOrigin><recordCreationDate encoding="w3cdtf">2020-05-30</recordCreationDate></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-8Z0M3W4F-H/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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