Serveur d'exploration sur les pandémies grippales

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A(H5N1) Virus Evolution in South East Asia

Identifieur interne : 000033 ( Hal/Curation ); précédent : 000032; suivant : 000034

A(H5N1) Virus Evolution in South East Asia

Auteurs : Ramona Gutiérrez [Cambodge] ; Monica Naughtin [Cambodge] ; Srey Viseth Horm [Cambodge] ; Sorn San [Cambodge] ; Philippe Buchy [Cambodge]

Source :

RBID : Hal:hal-00583197

English descriptors

Abstract

Highly Pathogenic Avian Influenza (HPAI) H5N1 virus is an ongoing public health and socio-economic challenge, particularly in South East Asia. H5N1 is now endemic in poultry in many countries, and represents a major pandemic threat. Here, we describe the evolution of H5N1 virus in South East Asia, the reassortment events leading to high genetic diversity in the region, and factors responsible for virus spread. The virus has evolved with genetic variations affecting virulence, drug-resistance, and adaptation to new host species. The constant surveillance of these changes is of primary importance in the global efforts of the scientific community.


Url:
DOI: 10.3390/v1030335

Links toward previous steps (curation, corpus...)


Links to Exploration step

Hal:hal-00583197

Le document en format XML

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<p>Highly Pathogenic Avian Influenza (HPAI) H5N1 virus is an ongoing public health and socio-economic challenge, particularly in South East Asia. H5N1 is now endemic in poultry in many countries, and represents a major pandemic threat. Here, we describe the evolution of H5N1 virus in South East Asia, the reassortment events leading to high genetic diversity in the region, and factors responsible for virus spread. The virus has evolved with genetic variations affecting virulence, drug-resistance, and adaptation to new host species. The constant surveillance of these changes is of primary importance in the global efforts of the scientific community.</p>
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