First introduction of pandemic influenza A/H1N1 and detection of respiratory viruses in pediatric patients in Central African Republic.
Identifieur interne : 000503 ( Hal/Checkpoint ); précédent : 000502; suivant : 000504First introduction of pandemic influenza A/H1N1 and detection of respiratory viruses in pediatric patients in Central African Republic.
Auteurs : Emmanuel Nakouné [République centrafricaine] ; Vianney Tricou [République centrafricaine] ; Alexandre Manirakiza [République centrafricaine] ; Francis Komoyo [République centrafricaine] ; Benjamin Selekon [République centrafricaine] ; Jean Chrysostome Gody [République centrafricaine] ; Kathleen Victoir [France] ; Philippe Buchy [Cambodge] ; Mirdad Kazanji [République centrafricaine]Source :
- Virology Journal [ 1743-422X ] ; 2013.
Abstract
BACKGROUND: Acute viral respiratory illnesses in children in sub-Saharan Africa have received relatively little attention, although they are much more frequent causes of morbidity and mortality than in developed countries. Active surveillance is essential to identify the causative agents and to improve clinical management, especially in the context of possible circulation of pandemic viruses. FINDINGS: A prospective study was conducted in the Central African Republic (CAR) between January and December 2010 among infants and children aged 0-15 years attending sentinel sites for influenza-like illness or acute respiratory illness. Nasopharyngeal swabs were collected, and one-step real-time and multiplex reverse transcription-polymerase chain reaction were used to detect respiratory viruses. Respiratory viruses were detected in 49 of the 329 (14.9%) nasopharyngeal samples: 29 (8.8%) contained influenza viruses (5 (1.5%) had pandemic influenza A/H1N1 virus and 24 (7.3%) had influenza B viruses), 11 (3.3%) contained parainfluenza viruses types 1 and 3 and 9 (2.7%) contained human respiratory syncytial virus. Most cases were detected during the rainy season in the CAR. Analysis of the amplicon sequences confirmed the identity of each detected virus. CONCLUSIONS: The influenza surveillance system in the CAR has provided valuable data on the seasonality of influenza and the circulation of other respiratory viruses. Our network could therefore play a valuable role in the prevention and control of influenza epidemics in the CAR.
Url:
DOI: 10.1186/1743-422X-10-49
Links toward previous steps (curation, corpus...)
Links to Exploration step
Hal:pasteur-00863484Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">First introduction of pandemic influenza A/H1N1 and detection of respiratory viruses in pediatric patients in Central African Republic.</title>
<author><name sortKey="Nakoune, Emmanuel" sort="Nakoune, Emmanuel" uniqKey="Nakoune E" first="Emmanuel" last="Nakouné">Emmanuel Nakouné</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Tricou, Vianney" sort="Tricou, Vianney" uniqKey="Tricou V" first="Vianney" last="Tricou">Vianney Tricou</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Manirakiza, Alexandre" sort="Manirakiza, Alexandre" uniqKey="Manirakiza A" first="Alexandre" last="Manirakiza">Alexandre Manirakiza</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Komoyo, Francis" sort="Komoyo, Francis" uniqKey="Komoyo F" first="Francis" last="Komoyo">Francis Komoyo</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Selekon, Benjamin" sort="Selekon, Benjamin" uniqKey="Selekon B" first="Benjamin" last="Selekon">Benjamin Selekon</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Gody, Jean Chrysostome" sort="Gody, Jean Chrysostome" uniqKey="Gody J" first="Jean Chrysostome" last="Gody">Jean Chrysostome Gody</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-135171" status="INCOMING"> <orgName>Complexe pédiatrique</orgName>
<desc> <address> <addrLine>Bangui</addrLine>
<country key="CF"></country>
</address>
</desc>
<listRelation> <relation active="#struct-332784" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-332784" type="direct"><org type="institution" xml:id="struct-332784" status="INCOMING"> <orgName>Complexe pédiatrique</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Victoir, Kathleen" sort="Victoir, Kathleen" uniqKey="Victoir K" first="Kathleen" last="Victoir">Kathleen Victoir</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-189141" status="VALID"> <orgName>Division International</orgName>
<desc> <address> <addrLine>25-28 rue du Docteur Roux, 75015 Paris</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-300027" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300027" type="direct"><org type="institution" xml:id="struct-300027" status="VALID"> <idno type="IdRef">027936643</idno>
<idno type="ISNI">0000 0001 2353 6535</idno>
<orgName>Institut Pasteur [Paris]</orgName>
<date type="start">1887-06-04</date>
<desc> <address> <addrLine>25-28, rue du docteur Roux, 75724 Paris cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.pasteur.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Buchy, Philippe" sort="Buchy, Philippe" uniqKey="Buchy P" first="Philippe" last="Buchy">Philippe Buchy</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-54022" status="VALID"> <orgName>Institut Pasteur du Cambodge</orgName>
<desc> <address> <addrLine>BP 983 - 5 , Boulevard Monivong, Phnom Penh</addrLine>
<country key="KH"></country>
</address>
<ref type="url">http://www.pasteur-kh.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Cambodge</country>
</affiliation>
</author>
<author><name sortKey="Kazanji, Mirdad" sort="Kazanji, Mirdad" uniqKey="Kazanji M" first="Mirdad" last="Kazanji">Mirdad Kazanji</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:pasteur-00863484</idno>
<idno type="halId">pasteur-00863484</idno>
<idno type="halUri">https://hal-riip.archives-ouvertes.fr/pasteur-00863484</idno>
<idno type="url">https://hal-riip.archives-ouvertes.fr/pasteur-00863484</idno>
<idno type="doi">10.1186/1743-422X-10-49</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Hal/Corpus">000232</idno>
<idno type="wicri:Area/Hal/Curation">000232</idno>
<idno type="wicri:Area/Hal/Checkpoint">000503</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000503</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">First introduction of pandemic influenza A/H1N1 and detection of respiratory viruses in pediatric patients in Central African Republic.</title>
<author><name sortKey="Nakoune, Emmanuel" sort="Nakoune, Emmanuel" uniqKey="Nakoune E" first="Emmanuel" last="Nakouné">Emmanuel Nakouné</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Tricou, Vianney" sort="Tricou, Vianney" uniqKey="Tricou V" first="Vianney" last="Tricou">Vianney Tricou</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Manirakiza, Alexandre" sort="Manirakiza, Alexandre" uniqKey="Manirakiza A" first="Alexandre" last="Manirakiza">Alexandre Manirakiza</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Komoyo, Francis" sort="Komoyo, Francis" uniqKey="Komoyo F" first="Francis" last="Komoyo">Francis Komoyo</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Selekon, Benjamin" sort="Selekon, Benjamin" uniqKey="Selekon B" first="Benjamin" last="Selekon">Benjamin Selekon</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Gody, Jean Chrysostome" sort="Gody, Jean Chrysostome" uniqKey="Gody J" first="Jean Chrysostome" last="Gody">Jean Chrysostome Gody</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-135171" status="INCOMING"> <orgName>Complexe pédiatrique</orgName>
<desc> <address> <addrLine>Bangui</addrLine>
<country key="CF"></country>
</address>
</desc>
<listRelation> <relation active="#struct-332784" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-332784" type="direct"><org type="institution" xml:id="struct-332784" status="INCOMING"> <orgName>Complexe pédiatrique</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
<author><name sortKey="Victoir, Kathleen" sort="Victoir, Kathleen" uniqKey="Victoir K" first="Kathleen" last="Victoir">Kathleen Victoir</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-189141" status="VALID"> <orgName>Division International</orgName>
<desc> <address> <addrLine>25-28 rue du Docteur Roux, 75015 Paris</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-300027" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300027" type="direct"><org type="institution" xml:id="struct-300027" status="VALID"> <idno type="IdRef">027936643</idno>
<idno type="ISNI">0000 0001 2353 6535</idno>
<orgName>Institut Pasteur [Paris]</orgName>
<date type="start">1887-06-04</date>
<desc> <address> <addrLine>25-28, rue du docteur Roux, 75724 Paris cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://www.pasteur.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Buchy, Philippe" sort="Buchy, Philippe" uniqKey="Buchy P" first="Philippe" last="Buchy">Philippe Buchy</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-54022" status="VALID"> <orgName>Institut Pasteur du Cambodge</orgName>
<desc> <address> <addrLine>BP 983 - 5 , Boulevard Monivong, Phnom Penh</addrLine>
<country key="KH"></country>
</address>
<ref type="url">http://www.pasteur-kh.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Cambodge</country>
</affiliation>
</author>
<author><name sortKey="Kazanji, Mirdad" sort="Kazanji, Mirdad" uniqKey="Kazanji M" first="Mirdad" last="Kazanji">Mirdad Kazanji</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-55916" status="VALID"> <orgName>Institut Pasteur de Bangui</orgName>
<desc> <address> <addrLine>B.P. 983 Bangui</addrLine>
<country key="CF"></country>
</address>
<ref type="url">http://pasteur-bangui.org/</ref>
</desc>
<listRelation> <relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-301247" type="direct"><org type="regroupinstitution" xml:id="struct-301247" status="VALID"> <orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc> <address> <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>République centrafricaine</country>
</affiliation>
</author>
</analytic>
<idno type="DOI">10.1186/1743-422X-10-49</idno>
<series><title level="j">Virology Journal</title>
<idno type="ISSN">1743-422X</idno>
<imprint><date type="datePub">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="mix" xml:lang="it"><term>Acute respiratory illness</term>
<term>Influenza B</term>
<term>Molecular diagnosis</term>
<term>Pandemic influenza A/H1N1 2009</term>
<term>Parainfluenza virus</term>
<term>Pediatric patients</term>
<term>Respiratory syncytial virus</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"> <p>BACKGROUND: Acute viral respiratory illnesses in children in sub-Saharan Africa have received relatively little attention, although they are much more frequent causes of morbidity and mortality than in developed countries. Active surveillance is essential to identify the causative agents and to improve clinical management, especially in the context of possible circulation of pandemic viruses. FINDINGS: A prospective study was conducted in the Central African Republic (CAR) between January and December 2010 among infants and children aged 0-15 years attending sentinel sites for influenza-like illness or acute respiratory illness. Nasopharyngeal swabs were collected, and one-step real-time and multiplex reverse transcription-polymerase chain reaction were used to detect respiratory viruses. Respiratory viruses were detected in 49 of the 329 (14.9%) nasopharyngeal samples: 29 (8.8%) contained influenza viruses (5 (1.5%) had pandemic influenza A/H1N1 virus and 24 (7.3%) had influenza B viruses), 11 (3.3%) contained parainfluenza viruses types 1 and 3 and 9 (2.7%) contained human respiratory syncytial virus. Most cases were detected during the rainy season in the CAR. Analysis of the amplicon sequences confirmed the identity of each detected virus. CONCLUSIONS: The influenza surveillance system in the CAR has provided valuable data on the seasonality of influenza and the circulation of other respiratory viruses. Our network could therefore play a valuable role in the prevention and control of influenza epidemics in the CAR.</p>
</div>
</front>
</TEI>
<hal api="V3"> <titleStmt> <title xml:lang="en">First introduction of pandemic influenza A/H1N1 and detection of respiratory viruses in pediatric patients in Central African Republic.</title>
<author role="aut"> <persName> <forename type="first">Emmanuel</forename>
<surname>Nakouné</surname>
</persName>
<idno type="halauthorid">764271</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Vianney</forename>
<surname>Tricou</surname>
</persName>
<idno type="halauthorid">889334</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Alexandre</forename>
<surname>Manirakiza</surname>
</persName>
<idno type="halauthorid">551909</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Francis</forename>
<surname>Komoyo</surname>
</persName>
<idno type="halauthorid">889335</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Benjamin</forename>
<surname>Selekon</surname>
</persName>
<idno type="halauthorid">764273</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Jean Chrysostome</forename>
<surname>Gody</surname>
</persName>
<idno type="halauthorid">853565</idno>
<affiliation ref="#struct-135171"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Kathleen</forename>
<surname>Victoir</surname>
</persName>
<idno type="halauthorid">709990</idno>
<affiliation ref="#struct-189141"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Philippe</forename>
<surname>Buchy</surname>
</persName>
<email type="md5">3eb2e424c733e6c3dbc756ecb79b6cd9</email>
<email type="domain">pasteur-kh.org</email>
<idno type="halauthorid">397584</idno>
<affiliation ref="#struct-54022"></affiliation>
</author>
<author role="crp"> <persName> <forename type="first">Mirdad</forename>
<surname>Kazanji</surname>
</persName>
<email type="md5">64e6d26af9ef892dbd23b24ceeeeba9d</email>
<email type="domain">pasteur.fr</email>
<idno type="halauthorid">551710</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<editor role="depositor"> <persName> <forename>Philippe</forename>
<surname>Buchy</surname>
</persName>
<email type="md5">3eb2e424c733e6c3dbc756ecb79b6cd9</email>
<email type="domain">pasteur-kh.org</email>
</editor>
<funder>This work was supported by the French Ministry of Health and the Office of the Assistant Secretary for Preparedness and Response within the US Department of Health and Human Services (grant number 6 IDESP060001-01-01) through the International Network of Pasteur Institutes</funder>
</titleStmt>
<editionStmt> <edition n="v1" type="current"> <date type="whenSubmitted">2013-09-19 05:26:14</date>
<date type="whenModified">2020-01-13 17:08:15</date>
<date type="whenReleased">2014-01-09 15:31:46</date>
<date type="whenProduced">2013</date>
<date type="whenEndEmbargoed">2013-09-19</date>
<ref type="file" target="https://hal-riip.archives-ouvertes.fr/pasteur-00863484/document"> <date notBefore="2013-09-19"></date>
</ref>
<ref type="file" subtype="greenPublisher" n="1" target="https://hal-riip.archives-ouvertes.fr/pasteur-00863484/file/First_introduction_of_pandemic_influenza_A_H1N1_and_detection_of_respiratory_viruses_in_pediatric_patients_in_Central_African_Republic_NakounA_E_2013_.pdf"> <date notBefore="2013-09-19"></date>
</ref>
<ref type="externalLink" target="https://virologyj.biomedcentral.com/track/pdf/10.1186/1743-422X-10-49"></ref>
</edition>
<respStmt> <resp>contributor</resp>
<name key="177006"> <persName> <forename>Philippe</forename>
<surname>Buchy</surname>
</persName>
<email type="md5">3eb2e424c733e6c3dbc756ecb79b6cd9</email>
<email type="domain">pasteur-kh.org</email>
</name>
</respStmt>
</editionStmt>
<publicationStmt> <distributor>CCSD</distributor>
<idno type="halId">pasteur-00863484</idno>
<idno type="halUri">https://hal-riip.archives-ouvertes.fr/pasteur-00863484</idno>
<idno type="halBibtex">nakoune:pasteur-00863484</idno>
<idno type="halRefHtml">Virology Journal, BioMed Central, 2013, 10 (49), pp.49. ⟨10.1186/1743-422X-10-49⟩</idno>
<idno type="halRef">Virology Journal, BioMed Central, 2013, 10 (49), pp.49. ⟨10.1186/1743-422X-10-49⟩</idno>
</publicationStmt>
<seriesStmt> <idno type="stamp" n="PASTEUR">Institut Pasteur</idno>
<idno type="stamp" n="RIIP_PARIS">Institut Pasteur de Paris</idno>
<idno type="stamp" n="RIIP_CAMBODGE" corresp="RIIP">Institut Pasteur du Cambodge</idno>
<idno type="stamp" n="RIIP">Institut Pasteur RIIP (Réseau International)</idno>
<idno type="stamp" n="RIIP_BANGUI" corresp="RIIP">Institut Pasteur de Bangui</idno>
</seriesStmt>
<notesStmt> <note type="audience" n="2">International</note>
<note type="popular" n="0">No</note>
<note type="peer" n="1">Yes</note>
</notesStmt>
<sourceDesc> <biblStruct> <analytic> <title xml:lang="en">First introduction of pandemic influenza A/H1N1 and detection of respiratory viruses in pediatric patients in Central African Republic.</title>
<author role="aut"> <persName> <forename type="first">Emmanuel</forename>
<surname>Nakouné</surname>
</persName>
<idno type="halauthorid">764271</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Vianney</forename>
<surname>Tricou</surname>
</persName>
<idno type="halauthorid">889334</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Alexandre</forename>
<surname>Manirakiza</surname>
</persName>
<idno type="halauthorid">551909</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Francis</forename>
<surname>Komoyo</surname>
</persName>
<idno type="halauthorid">889335</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Benjamin</forename>
<surname>Selekon</surname>
</persName>
<idno type="halauthorid">764273</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Jean Chrysostome</forename>
<surname>Gody</surname>
</persName>
<idno type="halauthorid">853565</idno>
<affiliation ref="#struct-135171"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Kathleen</forename>
<surname>Victoir</surname>
</persName>
<idno type="halauthorid">709990</idno>
<affiliation ref="#struct-189141"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Philippe</forename>
<surname>Buchy</surname>
</persName>
<email type="md5">3eb2e424c733e6c3dbc756ecb79b6cd9</email>
<email type="domain">pasteur-kh.org</email>
<idno type="halauthorid">397584</idno>
<affiliation ref="#struct-54022"></affiliation>
</author>
<author role="crp"> <persName> <forename type="first">Mirdad</forename>
<surname>Kazanji</surname>
</persName>
<email type="md5">64e6d26af9ef892dbd23b24ceeeeba9d</email>
<email type="domain">pasteur.fr</email>
<idno type="halauthorid">551710</idno>
<affiliation ref="#struct-55916"></affiliation>
</author>
</analytic>
<monogr> <idno type="halJournalId" status="VALID">2506</idno>
<idno type="issn">1743-422X</idno>
<title level="j">Virology Journal</title>
<imprint> <publisher>BioMed Central</publisher>
<biblScope unit="volume">10</biblScope>
<biblScope unit="issue">49</biblScope>
<biblScope unit="pp">49</biblScope>
<date type="datePub">2013</date>
<date type="dateEpub">2013-02-08</date>
</imprint>
</monogr>
<idno type="doi">10.1186/1743-422X-10-49</idno>
<idno type="pubmed">23391188</idno>
</biblStruct>
</sourceDesc>
<profileDesc> <langUsage> <language ident="en">English</language>
</langUsage>
<textClass> <keywords scheme="author"> <term xml:lang="it">Molecular diagnosis</term>
<term xml:lang="it">Acute respiratory illness</term>
<term xml:lang="it">Pandemic influenza A/H1N1 2009</term>
<term xml:lang="it">Influenza B</term>
<term xml:lang="it">Respiratory syncytial virus</term>
<term xml:lang="it">Parainfluenza virus</term>
<term xml:lang="it">Pediatric patients</term>
</keywords>
<classCode scheme="halDomain" n="sdv.mp.vir">Life Sciences [q-bio]/Microbiology and Parasitology/Virology</classCode>
<classCode scheme="halTypology" n="ART">Journal articles</classCode>
</textClass>
<abstract xml:lang="en"> <p>BACKGROUND: Acute viral respiratory illnesses in children in sub-Saharan Africa have received relatively little attention, although they are much more frequent causes of morbidity and mortality than in developed countries. Active surveillance is essential to identify the causative agents and to improve clinical management, especially in the context of possible circulation of pandemic viruses. FINDINGS: A prospective study was conducted in the Central African Republic (CAR) between January and December 2010 among infants and children aged 0-15 years attending sentinel sites for influenza-like illness or acute respiratory illness. Nasopharyngeal swabs were collected, and one-step real-time and multiplex reverse transcription-polymerase chain reaction were used to detect respiratory viruses. Respiratory viruses were detected in 49 of the 329 (14.9%) nasopharyngeal samples: 29 (8.8%) contained influenza viruses (5 (1.5%) had pandemic influenza A/H1N1 virus and 24 (7.3%) had influenza B viruses), 11 (3.3%) contained parainfluenza viruses types 1 and 3 and 9 (2.7%) contained human respiratory syncytial virus. Most cases were detected during the rainy season in the CAR. Analysis of the amplicon sequences confirmed the identity of each detected virus. CONCLUSIONS: The influenza surveillance system in the CAR has provided valuable data on the seasonality of influenza and the circulation of other respiratory viruses. Our network could therefore play a valuable role in the prevention and control of influenza epidemics in the CAR.</p>
</abstract>
<particDesc> <org type="consortium">Nakouné E</org>
<org type="consortium">Tricou V</org>
<org type="consortium">Manirakiza A</org>
<org type="consortium">Komoyo F</org>
<org type="consortium">Selekon B</org>
<org type="consortium">Gody JC</org>
<org type="consortium">Victoir K</org>
<org type="consortium">Buchy P</org>
<org type="consortium">Kazanji M.</org>
</particDesc>
</profileDesc>
</hal>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/Hal/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000503 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Hal/Checkpoint/biblio.hfd -nk 000503 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= PandemieGrippaleV1 |flux= Hal |étape= Checkpoint |type= RBID |clé= Hal:pasteur-00863484 |texte= First introduction of pandemic influenza A/H1N1 and detection of respiratory viruses in pediatric patients in Central African Republic. }}
![]() | This area was generated with Dilib version V0.6.34. | ![]() |