PaleopathV1, PubMed, Corpus, bibRecord, 000214

Hand osteoarthritis and bone loss: is there an inverse relationship?

Identifieur interne : 000214 ( PubMed/Corpus ); précédent : 000213; suivant : 000215

Hand osteoarthritis and bone loss: is there an inverse relationship?

Auteurs : Elizabeth Weiss

Source :

Homo : internationale Zeitschrift fur die vergleichende Forschung am Menschen [ 1618-1301 ] ; 2013.

RBID : pubmed:23830155

English descriptors

KwdEn :
- Adolescent, Adult, California, Female, Fossils, Hand, History, Ancient, Humans, Male, Osteoarthritis (history), Osteoarthritis (pathology), Osteoporosis (history), Osteoporosis (pathology), Paleopathology, Young Adult.
MESH :
- geographic : California.
- history : Osteoarthritis, Osteoporosis.
- pathology : Osteoarthritis, Osteoporosis.
- Adolescent, Adult, Female, Fossils, Hand, History, Ancient, Humans, Male, Paleopathology, Young Adult.

Abstract

An inverse relationship between osteoarthritis (OA) and bone loss has been supported in clinical research, but there has been little research on bioarchaeological skeletal remains. The current study examines 115 adults from a prehistoric hunter-gatherer population to aid in determining whether hand OA and bone loss are negatively correlated. OA lipping is scored on a four-point scale on left and right trapezia, MC1s, and MC2s and then analyzed with regard to their relationships with sex, age, right MC2 cortical index, and left and right MC1 robusticity, midshaft circumference, and midshaft diameter values. With sexes and ages combined, higher OA scores are found in individuals with greater midshaft diameters. However, lower cortical indices were found in individuals with higher right MC2 OA scores. The data presented tenuously support that bone loss is lower in individuals with more severe osteoarthritis, but age-related changes in bone deposition may make cortical index and other external shaft dimensions an unsuitable variable to examine this relationship.

DOI: 10.1016/j.jchb.2013.06.001
PubMed: 23830155

Links to Exploration step

pubmed:23830155

Le document en format XML

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<author><name sortKey="Weiss, Elizabeth" sort="Weiss, Elizabeth" uniqKey="Weiss E" first="Elizabeth" last="Weiss">Elizabeth Weiss</name>
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<front><div type="abstract" xml:lang="en">An inverse relationship between osteoarthritis (OA) and bone loss has been supported in clinical research, but there has been little research on bioarchaeological skeletal remains. The current study examines 115 adults from a prehistoric hunter-gatherer population to aid in determining whether hand OA and bone loss are negatively correlated. OA lipping is scored on a four-point scale on left and right trapezia, MC1s, and MC2s and then analyzed with regard to their relationships with sex, age, right MC2 cortical index, and left and right MC1 robusticity, midshaft circumference, and midshaft diameter values. With sexes and ages combined, higher OA scores are found in individuals with greater midshaft diameters. However, lower cortical indices were found in individuals with higher right MC2 OA scores. The data presented tenuously support that bone loss is lower in individuals with more severe osteoarthritis, but age-related changes in bone deposition may make cortical index and other external shaft dimensions an unsuitable variable to examine this relationship.</div>
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<Abstract><AbstractText>An inverse relationship between osteoarthritis (OA) and bone loss has been supported in clinical research, but there has been little research on bioarchaeological skeletal remains. The current study examines 115 adults from a prehistoric hunter-gatherer population to aid in determining whether hand OA and bone loss are negatively correlated. OA lipping is scored on a four-point scale on left and right trapezia, MC1s, and MC2s and then analyzed with regard to their relationships with sex, age, right MC2 cortical index, and left and right MC1 robusticity, midshaft circumference, and midshaft diameter values. With sexes and ages combined, higher OA scores are found in individuals with greater midshaft diameters. However, lower cortical indices were found in individuals with higher right MC2 OA scores. The data presented tenuously support that bone loss is lower in individuals with more severe osteoarthritis, but age-related changes in bone deposition may make cortical index and other external shaft dimensions an unsuitable variable to examine this relationship.</AbstractText>
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Hand osteoarthritis and bone loss: is there an inverse relationship?

Hand osteoarthritis and bone loss: is there an inverse relationship?

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki