PaleopathV1, Ncbi, Merge, bibRecord, 000D08

Did Tutankhamun suffer from hypophosphatasia?--A hypothetical approach.

Identifieur interne : 000D08 ( Ncbi/Merge ); précédent : 000D07; suivant : 000D09

Did Tutankhamun suffer from hypophosphatasia?--A hypothetical approach.

Auteurs : Gerald Brandt

Source :

Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur [ 0003-5548 ] ; 2013.

RBID : pubmed:24466636

Descripteurs français

Wicri :
- geographic : Égypte.

English descriptors

KwdEn :
- Adolescent, Alkaline Phosphatase (genetics), Child, Child, Preschool, Egypt, Female, Femoral Fractures (history), Femoral Fractures (pathology), History, Ancient, Humans, Hypophosphatasia (history), Hypophosphatasia (pathology), Male, Middle Aged, Mummies (history), Mummies (pathology), Necrosis, Paleopathology.
MESH :
- chemical , genetics : Alkaline Phosphatase.
- geographic : Egypt.
- history : Femoral Fractures, Hypophosphatasia, Mummies.
- pathology : Femoral Fractures, Hypophosphatasia, Mummies.
- Adolescent, Child, Child, Preschool, Female, History, Ancient, Humans, Male, Middle Aged, Necrosis, Paleopathology.

Abstract

Between 2005 and 2010 new efforts have been undertaken to shed light on the life and death of Tutankhamun--for the first time with the aid of modern scientific methods like CT scans and DNA analysis. The publication of a paper in the Journal of the American Medical Association in February 2010, that stated the famous pharaoh died of a combination of Malaria and Köhler's disease II, provoked objections from various sides. Based on new and existing findings, the author has developed the theory that Tutankhamun might, instead, have suffered from hypophosphatasia, an inherited metabolic disorder that affects especially the musculo-skeletal system in many ways. Hypophosphatasia (HPP) can be highly variable in its clinical manifestations and can be difficult to diagnose. The author has compiled both medical and archaeological findings to support his theory and suggests that existing DNA samples of Tutankhamun and other members of his family should be tested for defects on the ALPL gene.

PubMed: 24466636

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pubmed:24466636

Le document en format XML

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<front><div type="abstract" xml:lang="en">Between 2005 and 2010 new efforts have been undertaken to shed light on the life and death of Tutankhamun--for the first time with the aid of modern scientific methods like CT scans and DNA analysis. The publication of a paper in the Journal of the American Medical Association in February 2010, that stated the famous pharaoh died of a combination of Malaria and Köhler's disease II, provoked objections from various sides. Based on new and existing findings, the author has developed the theory that Tutankhamun might, instead, have suffered from hypophosphatasia, an inherited metabolic disorder that affects especially the musculo-skeletal system in many ways. Hypophosphatasia (HPP) can be highly variable in its clinical manifestations and can be difficult to diagnose. The author has compiled both medical and archaeological findings to support his theory and suggests that existing DNA samples of Tutankhamun and other members of his family should be tested for defects on the ALPL gene.</div>
</front>
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<Month>01</Month>
<Day>28</Day>
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<DateCompleted><Year>2014</Year>
<Month>02</Month>
<Day>18</Day>
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<Title>Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur</Title>
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<QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009336" MajorTopicYN="N">Necrosis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010164" MajorTopicYN="N">Paleopathology</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<PersonalNameSubjectList><PersonalNameSubject><LastName>Tutankhamun</LastName>
</PersonalNameSubject>
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Did Tutankhamun suffer from hypophosphatasia?--A hypothetical approach.

Did Tutankhamun suffer from hypophosphatasia?--A hypothetical approach.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki