Direct comparison between regional cerebral metabolism in progressive supranuclear palsy and Parkinson's disease.
Identifieur interne : 003055 ( PubMed/Curation ); précédent : 003054; suivant : 003056Direct comparison between regional cerebral metabolism in progressive supranuclear palsy and Parkinson's disease.
Auteurs : Reinoud C. Klein [Pays-Bas] ; Bauke M. De Jong ; Joeke J. De Vries ; Klaus L. LeendersSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2005.
English descriptors
- KwdEn :
- Aged, Blood Glucose (metabolism), Brain Mapping, Cerebral Cortex (metabolism), Cerebral Cortex (radionuclide imaging), Female, Fluorodeoxyglucose F18 (metabolism), Humans, Image Processing, Computer-Assisted (methods), Male, Middle Aged, Parkinson Disease (metabolism), Parkinson Disease (radionuclide imaging), Positron-Emission Tomography (methods), Regional Blood Flow (physiology), Supranuclear Palsy, Progressive (metabolism), Supranuclear Palsy, Progressive (radionuclide imaging).
- MESH :
- chemical , metabolism : Blood Glucose, Fluorodeoxyglucose F18.
- metabolism : Cerebral Cortex, Parkinson Disease, Supranuclear Palsy, Progressive.
- methods : Image Processing, Computer-Assisted, Positron-Emission Tomography.
- physiology : Regional Blood Flow.
- radionuclide imaging : Cerebral Cortex, Parkinson Disease, Supranuclear Palsy, Progressive.
- Aged, Brain Mapping, Female, Humans, Male, Middle Aged.
Abstract
The differentiation between progressive supranuclear palsy (PSP) and Parkinson's disease (PD) may be difficult, especially in the early stages of disease. Positron emission tomography potentially provides a tool for making such a distinction. To identify key features in the spatial distributions of cerebral glucose metabolism, 18F-fluorodeoxyglucose (FDG) measurements of 10 patients with probable or possible PSP were directly compared with those of 9 PD patients. This analysis was done with statistic parametric mapping. After normalization of global brain uptake, in PSP, relative uptake of FDG was reduced in the caudal (motor) part of the anterior cingulate gyrus (Brodmann's area BA 24; P < 0.05, corrected for multiple comparisons). At a lower threshold, an additional decrease was present in the dorsal mesencephalon. In PD, relative hypometabolism was seen in extrastriate visual, ventrolateral temporal, posterior parietal, and orbitofrontal regions. Only reduction in the right fusiform gyrus and the lateral extrastriate visual cortex reached statistical significance. We concluded that particularly the reduction of medial frontal metabolism may be a valuable diagnostic imaging parameter in distinguishing PSP from PD. For PD, a possible association between occipitotemporal FDG decrease and vulnerability to hallucinations is suggested.
DOI: 10.1002/mds.20493
PubMed: 15858809
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :003055
Links to Exploration step
pubmed:15858809Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Direct comparison between regional cerebral metabolism in progressive supranuclear palsy and Parkinson's disease.</title>
<author><name sortKey="Klein, Reinoud C" sort="Klein, Reinoud C" uniqKey="Klein R" first="Reinoud C" last="Klein">Reinoud C. Klein</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University Hospital Groningen, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, University Hospital Groningen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Jong, Bauke M" sort="De Jong, Bauke M" uniqKey="De Jong B" first="Bauke M" last="De Jong">Bauke M. De Jong</name>
</author>
<author><name sortKey="De Vries, Joeke J" sort="De Vries, Joeke J" uniqKey="De Vries J" first="Joeke J" last="De Vries">Joeke J. De Vries</name>
</author>
<author><name sortKey="Leenders, Klaus L" sort="Leenders, Klaus L" uniqKey="Leenders K" first="Klaus L" last="Leenders">Klaus L. Leenders</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2005">2005</date>
<idno type="doi">10.1002/mds.20493</idno>
<idno type="RBID">pubmed:15858809</idno>
<idno type="pmid">15858809</idno>
<idno type="wicri:Area/PubMed/Corpus">003055</idno>
<idno type="wicri:Area/PubMed/Curation">003055</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Direct comparison between regional cerebral metabolism in progressive supranuclear palsy and Parkinson's disease.</title>
<author><name sortKey="Klein, Reinoud C" sort="Klein, Reinoud C" uniqKey="Klein R" first="Reinoud C" last="Klein">Reinoud C. Klein</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University Hospital Groningen, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, University Hospital Groningen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Jong, Bauke M" sort="De Jong, Bauke M" uniqKey="De Jong B" first="Bauke M" last="De Jong">Bauke M. De Jong</name>
</author>
<author><name sortKey="De Vries, Joeke J" sort="De Vries, Joeke J" uniqKey="De Vries J" first="Joeke J" last="De Vries">Joeke J. De Vries</name>
</author>
<author><name sortKey="Leenders, Klaus L" sort="Leenders, Klaus L" uniqKey="Leenders K" first="Klaus L" last="Leenders">Klaus L. Leenders</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2005" type="published">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Blood Glucose (metabolism)</term>
<term>Brain Mapping</term>
<term>Cerebral Cortex (metabolism)</term>
<term>Cerebral Cortex (radionuclide imaging)</term>
<term>Female</term>
<term>Fluorodeoxyglucose F18 (metabolism)</term>
<term>Humans</term>
<term>Image Processing, Computer-Assisted (methods)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (metabolism)</term>
<term>Parkinson Disease (radionuclide imaging)</term>
<term>Positron-Emission Tomography (methods)</term>
<term>Regional Blood Flow (physiology)</term>
<term>Supranuclear Palsy, Progressive (metabolism)</term>
<term>Supranuclear Palsy, Progressive (radionuclide imaging)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Blood Glucose</term>
<term>Fluorodeoxyglucose F18</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Cerebral Cortex</term>
<term>Parkinson Disease</term>
<term>Supranuclear Palsy, Progressive</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Image Processing, Computer-Assisted</term>
<term>Positron-Emission Tomography</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Regional Blood Flow</term>
</keywords>
<keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Cerebral Cortex</term>
<term>Parkinson Disease</term>
<term>Supranuclear Palsy, Progressive</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Brain Mapping</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The differentiation between progressive supranuclear palsy (PSP) and Parkinson's disease (PD) may be difficult, especially in the early stages of disease. Positron emission tomography potentially provides a tool for making such a distinction. To identify key features in the spatial distributions of cerebral glucose metabolism, 18F-fluorodeoxyglucose (FDG) measurements of 10 patients with probable or possible PSP were directly compared with those of 9 PD patients. This analysis was done with statistic parametric mapping. After normalization of global brain uptake, in PSP, relative uptake of FDG was reduced in the caudal (motor) part of the anterior cingulate gyrus (Brodmann's area BA 24; P < 0.05, corrected for multiple comparisons). At a lower threshold, an additional decrease was present in the dorsal mesencephalon. In PD, relative hypometabolism was seen in extrastriate visual, ventrolateral temporal, posterior parietal, and orbitofrontal regions. Only reduction in the right fusiform gyrus and the lateral extrastriate visual cortex reached statistical significance. We concluded that particularly the reduction of medial frontal metabolism may be a valuable diagnostic imaging parameter in distinguishing PSP from PD. For PD, a possible association between occipitotemporal FDG decrease and vulnerability to hallucinations is suggested.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">15858809</PMID>
<DateCreated><Year>2005</Year>
<Month>08</Month>
<Day>04</Day>
</DateCreated>
<DateCompleted><Year>2005</Year>
<Month>10</Month>
<Day>19</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN>
<JournalIssue CitedMedium="Print"><Volume>20</Volume>
<Issue>8</Issue>
<PubDate><Year>2005</Year>
<Month>Aug</Month>
</PubDate>
</JournalIssue>
<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
</Journal>
<ArticleTitle>Direct comparison between regional cerebral metabolism in progressive supranuclear palsy and Parkinson's disease.</ArticleTitle>
<Pagination><MedlinePgn>1021-30</MedlinePgn>
</Pagination>
<Abstract><AbstractText>The differentiation between progressive supranuclear palsy (PSP) and Parkinson's disease (PD) may be difficult, especially in the early stages of disease. Positron emission tomography potentially provides a tool for making such a distinction. To identify key features in the spatial distributions of cerebral glucose metabolism, 18F-fluorodeoxyglucose (FDG) measurements of 10 patients with probable or possible PSP were directly compared with those of 9 PD patients. This analysis was done with statistic parametric mapping. After normalization of global brain uptake, in PSP, relative uptake of FDG was reduced in the caudal (motor) part of the anterior cingulate gyrus (Brodmann's area BA 24; P < 0.05, corrected for multiple comparisons). At a lower threshold, an additional decrease was present in the dorsal mesencephalon. In PD, relative hypometabolism was seen in extrastriate visual, ventrolateral temporal, posterior parietal, and orbitofrontal regions. Only reduction in the right fusiform gyrus and the lateral extrastriate visual cortex reached statistical significance. We concluded that particularly the reduction of medial frontal metabolism may be a valuable diagnostic imaging parameter in distinguishing PSP from PD. For PD, a possible association between occipitotemporal FDG decrease and vulnerability to hallucinations is suggested.</AbstractText>
<CopyrightInformation>Copyright 2005 Movement Disorder Society</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Klein</LastName>
<ForeName>Reinoud C</ForeName>
<Initials>RC</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital Groningen, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>de Jong</LastName>
<ForeName>Bauke M</ForeName>
<Initials>BM</Initials>
</Author>
<Author ValidYN="Y"><LastName>de Vries</LastName>
<ForeName>Joeke J</ForeName>
<Initials>JJ</Initials>
</Author>
<Author ValidYN="Y"><LastName>Leenders</LastName>
<ForeName>Klaus L</ForeName>
<Initials>KL</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Mov Disord</MedlineTA>
<NlmUniqueID>8610688</NlmUniqueID>
<ISSNLinking>0885-3185</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D001786">Blood Glucose</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0Z5B2CJX4D</RegistryNumber>
<NameOfSubstance UI="D019788">Fluorodeoxyglucose F18</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001786">Blood Glucose</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000378">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001931">Brain Mapping</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002540">Cerebral Cortex</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000378">metabolism</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000531">radionuclide imaging</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D019788">Fluorodeoxyglucose F18</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000378">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007091">Image Processing, Computer-Assisted</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000378">metabolism</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000531">radionuclide imaging</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D049268">Positron-Emission Tomography</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012039">Regional Blood Flow</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D013494">Supranuclear Palsy, Progressive</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000378">metabolism</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000531">radionuclide imaging</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2005</Year>
<Month>4</Month>
<Day>29</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2005</Year>
<Month>10</Month>
<Day>20</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2005</Year>
<Month>4</Month>
<Day>29</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="doi">10.1002/mds.20493</ArticleId>
<ArticleId IdType="pubmed">15858809</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003055 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 003055 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= PubMed |étape= Curation |type= RBID |clé= pubmed:15858809 |texte= Direct comparison between regional cerebral metabolism in progressive supranuclear palsy and Parkinson's disease. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:15858809" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \ | NlmPubMed2Wicri -a MovDisordV3
This area was generated with Dilib version V0.6.23. |