Atypical movement disorders in antiphospholipid syndrome.
Identifieur interne : 002D33 ( PubMed/Curation ); précédent : 002D32; suivant : 002D34Atypical movement disorders in antiphospholipid syndrome.
Auteurs : Davide Martino [Royaume-Uni] ; Nee-Kong Chew ; Pablo Mir ; Mark J. Edwards ; Niall P. Quinn ; Kailash P. BhatiaSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.
English descriptors
- KwdEn :
- Adolescent, Antiphospholipid Syndrome (diagnosis), Antiphospholipid Syndrome (drug therapy), Antiphospholipid Syndrome (physiopathology), Brain (pathology), Brain (physiopathology), Cerebral Infarction (diagnosis), Cerebral Infarction (drug therapy), Cerebral Infarction (physiopathology), Diagnosis, Differential, Dyskinesias (diagnosis), Dyskinesias (drug therapy), Dyskinesias (physiopathology), Electroencephalography (drug effects), Electromyography (drug effects), Female, Follow-Up Studies, Frontal Lobe (pathology), Frontal Lobe (physiopathology), Humans, Lupus Erythematosus, Systemic (diagnosis), Lupus Erythematosus, Systemic (drug therapy), Lupus Erythematosus, Systemic (physiopathology), Magnetic Resonance Imaging, Middle Aged, Movement Disorders (diagnosis), Movement Disorders (drug therapy), Movement Disorders (physiopathology), Myoclonus (diagnosis), Myoclonus (drug therapy), Myoclonus (physiopathology), Neurologic Examination (drug effects), Neuropsychological Tests, Occipital Lobe (pathology), Occipital Lobe (physiopathology), Phenindione (therapeutic use), Phenprocoumon (therapeutic use), Sneddon Syndrome (diagnosis), Sneddon Syndrome (drug therapy), Sneddon Syndrome (physiopathology), Spinocerebellar Degenerations (diagnosis), Spinocerebellar Degenerations (drug therapy), Spinocerebellar Degenerations (physiopathology), Tics (diagnosis), Tics (drug therapy), Tics (physiopathology), Tourette Syndrome (diagnosis), Tourette Syndrome (drug therapy), Tourette Syndrome (physiopathology), Tremor (diagnosis), Tremor (drug therapy), Tremor (physiopathology), Warfarin (therapeutic use).
- MESH :
- chemical , therapeutic use : Phenindione, Phenprocoumon, Warfarin.
- diagnosis : Antiphospholipid Syndrome, Cerebral Infarction, Dyskinesias, Lupus Erythematosus, Systemic, Movement Disorders, Myoclonus, Sneddon Syndrome, Spinocerebellar Degenerations, Tics, Tourette Syndrome, Tremor.
- drug effects : Electroencephalography, Electromyography, Neurologic Examination.
- drug therapy : Antiphospholipid Syndrome, Cerebral Infarction, Dyskinesias, Lupus Erythematosus, Systemic, Movement Disorders, Myoclonus, Sneddon Syndrome, Spinocerebellar Degenerations, Tics, Tourette Syndrome, Tremor.
- pathology : Brain, Frontal Lobe, Occipital Lobe.
- physiopathology : Antiphospholipid Syndrome, Brain, Cerebral Infarction, Dyskinesias, Frontal Lobe, Lupus Erythematosus, Systemic, Movement Disorders, Myoclonus, Occipital Lobe, Sneddon Syndrome, Spinocerebellar Degenerations, Tics, Tourette Syndrome, Tremor.
- Adolescent, Diagnosis, Differential, Female, Follow-Up Studies, Humans, Magnetic Resonance Imaging, Middle Aged, Neuropsychological Tests.
Abstract
Movement disorders have only rarely been reported in association with antiphospholipid syndrome (APS). In such cases, chorea is the most common disorder observed, with occasional reports of hemidystonia, Parkinsonism, and hemiballism. We report here on 3 cases of APS (3 women ages 16, 46, and 56 years) who presented with movement disorders, including tics, tremor, myoclonus, and a corticobasal syndrome, never or rarely reported in association with this disease. Mild executive dysfunction was observed in all 3 patients. We also report the successful treatment of two of these patients with mild oral anticoagulation (INR 2-3). Movement disorders in APS seem more clinically heterogeneous than previously thought. Oral anticoagulation should be considered in the treatment of movement disorders associated with APS.
DOI: 10.1002/mds.20842
PubMed: 16538618
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pubmed:16538618Le document en format XML
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<term>Brain (pathology)</term>
<term>Brain (physiopathology)</term>
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<term>Cerebral Infarction (drug therapy)</term>
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<term>Diagnosis, Differential</term>
<term>Dyskinesias (diagnosis)</term>
<term>Dyskinesias (drug therapy)</term>
<term>Dyskinesias (physiopathology)</term>
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<term>Follow-Up Studies</term>
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<term>Frontal Lobe (physiopathology)</term>
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<term>Lupus Erythematosus, Systemic (diagnosis)</term>
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<term>Lupus Erythematosus, Systemic (physiopathology)</term>
<term>Magnetic Resonance Imaging</term>
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<term>Neurologic Examination (drug effects)</term>
<term>Neuropsychological Tests</term>
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<term>Occipital Lobe (physiopathology)</term>
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<term>Diagnosis, Differential</term>
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<front><div type="abstract" xml:lang="en">Movement disorders have only rarely been reported in association with antiphospholipid syndrome (APS). In such cases, chorea is the most common disorder observed, with occasional reports of hemidystonia, Parkinsonism, and hemiballism. We report here on 3 cases of APS (3 women ages 16, 46, and 56 years) who presented with movement disorders, including tics, tremor, myoclonus, and a corticobasal syndrome, never or rarely reported in association with this disease. Mild executive dysfunction was observed in all 3 patients. We also report the successful treatment of two of these patients with mild oral anticoagulation (INR 2-3). Movement disorders in APS seem more clinically heterogeneous than previously thought. Oral anticoagulation should be considered in the treatment of movement disorders associated with APS.</div>
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<Abstract><AbstractText>Movement disorders have only rarely been reported in association with antiphospholipid syndrome (APS). In such cases, chorea is the most common disorder observed, with occasional reports of hemidystonia, Parkinsonism, and hemiballism. We report here on 3 cases of APS (3 women ages 16, 46, and 56 years) who presented with movement disorders, including tics, tremor, myoclonus, and a corticobasal syndrome, never or rarely reported in association with this disease. Mild executive dysfunction was observed in all 3 patients. We also report the successful treatment of two of these patients with mild oral anticoagulation (INR 2-3). Movement disorders in APS seem more clinically heterogeneous than previously thought. Oral anticoagulation should be considered in the treatment of movement disorders associated with APS.</AbstractText>
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