Paroxysmal dyskinesias in mice.
Identifieur interne : 002437 ( PubMed/Curation ); précédent : 002436; suivant : 002438Paroxysmal dyskinesias in mice.
Auteurs : Thomas L. Shirley [États-Unis] ; Lekha M. Rao ; Ellen J. Hess ; H A JinnahSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2008.
English descriptors
- KwdEn :
- MESH :
- genetics : Chorea.
- physiopathology : Chorea.
- Age Factors, Animals, Behavior, Animal, Disease Models, Animal, Mice, Mice, Inbred C57BL, Mice, Neurologic Mutants, Severity of Illness Index.
Abstract
Animal models of human disease are important tools for revealing the underlying mechanisms of pathophysiology and developing therapeutic strategies. Several unique mouse calcium channel mutants have been identified with nonepileptic, episodic dyskinetic movements that are phenotypically similar to human paroxysmal dyskinesias. In this report, video demonstrations of these motor attacks are provided for two previously described mouse mutants, tottering and lethargic, as well as a new one, rocker. Semiquantitative comparisons using two different rating scales reveal differences in attack morphology, severity, and duration among the strains. These mice provide three independent models of paroxysmal dyskinesia and support for prior proposals that channelopathies may underlie the human disorders.
DOI: 10.1002/mds.21829
PubMed: 17999434
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002437
Links to Exploration step
pubmed:17999434Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Paroxysmal dyskinesias in mice.</title>
<author><name sortKey="Shirley, Thomas L" sort="Shirley, Thomas L" uniqKey="Shirley T" first="Thomas L" last="Shirley">Thomas L. Shirley</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Johns Hopkins University, Baltimore, Maryland, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Johns Hopkins University, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rao, Lekha M" sort="Rao, Lekha M" uniqKey="Rao L" first="Lekha M" last="Rao">Lekha M. Rao</name>
</author>
<author><name sortKey="Hess, Ellen J" sort="Hess, Ellen J" uniqKey="Hess E" first="Ellen J" last="Hess">Ellen J. Hess</name>
</author>
<author><name sortKey="Jinnah, H A" sort="Jinnah, H A" uniqKey="Jinnah H" first="H A" last="Jinnah">H A Jinnah</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2008">2008</date>
<idno type="doi">10.1002/mds.21829</idno>
<idno type="RBID">pubmed:17999434</idno>
<idno type="pmid">17999434</idno>
<idno type="wicri:Area/PubMed/Corpus">002437</idno>
<idno type="wicri:Area/PubMed/Curation">002437</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Paroxysmal dyskinesias in mice.</title>
<author><name sortKey="Shirley, Thomas L" sort="Shirley, Thomas L" uniqKey="Shirley T" first="Thomas L" last="Shirley">Thomas L. Shirley</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Johns Hopkins University, Baltimore, Maryland, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Johns Hopkins University, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rao, Lekha M" sort="Rao, Lekha M" uniqKey="Rao L" first="Lekha M" last="Rao">Lekha M. Rao</name>
</author>
<author><name sortKey="Hess, Ellen J" sort="Hess, Ellen J" uniqKey="Hess E" first="Ellen J" last="Hess">Ellen J. Hess</name>
</author>
<author><name sortKey="Jinnah, H A" sort="Jinnah, H A" uniqKey="Jinnah H" first="H A" last="Jinnah">H A Jinnah</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2008" type="published">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age Factors</term>
<term>Animals</term>
<term>Behavior, Animal</term>
<term>Chorea (genetics)</term>
<term>Chorea (physiopathology)</term>
<term>Disease Models, Animal</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Mice, Neurologic Mutants</term>
<term>Severity of Illness Index</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Chorea</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Chorea</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Age Factors</term>
<term>Animals</term>
<term>Behavior, Animal</term>
<term>Disease Models, Animal</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Mice, Neurologic Mutants</term>
<term>Severity of Illness Index</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Animal models of human disease are important tools for revealing the underlying mechanisms of pathophysiology and developing therapeutic strategies. Several unique mouse calcium channel mutants have been identified with nonepileptic, episodic dyskinetic movements that are phenotypically similar to human paroxysmal dyskinesias. In this report, video demonstrations of these motor attacks are provided for two previously described mouse mutants, tottering and lethargic, as well as a new one, rocker. Semiquantitative comparisons using two different rating scales reveal differences in attack morphology, severity, and duration among the strains. These mice provide three independent models of paroxysmal dyskinesia and support for prior proposals that channelopathies may underlie the human disorders.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">17999434</PMID>
<DateCreated><Year>2008</Year>
<Month>02</Month>
<Day>04</Day>
</DateCreated>
<DateCompleted><Year>2008</Year>
<Month>05</Month>
<Day>08</Day>
</DateCompleted>
<DateRevised><Year>2014</Year>
<Month>09</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>23</Volume>
<Issue>2</Issue>
<PubDate><Year>2008</Year>
<Month>Jan</Month>
<Day>30</Day>
</PubDate>
</JournalIssue>
<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
</Journal>
<ArticleTitle>Paroxysmal dyskinesias in mice.</ArticleTitle>
<Pagination><MedlinePgn>259-64</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Animal models of human disease are important tools for revealing the underlying mechanisms of pathophysiology and developing therapeutic strategies. Several unique mouse calcium channel mutants have been identified with nonepileptic, episodic dyskinetic movements that are phenotypically similar to human paroxysmal dyskinesias. In this report, video demonstrations of these motor attacks are provided for two previously described mouse mutants, tottering and lethargic, as well as a new one, rocker. Semiquantitative comparisons using two different rating scales reveal differences in attack morphology, severity, and duration among the strains. These mice provide three independent models of paroxysmal dyskinesia and support for prior proposals that channelopathies may underlie the human disorders.</AbstractText>
<CopyrightInformation>2007 Movement Disorder Society</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Shirley</LastName>
<ForeName>Thomas L</ForeName>
<Initials>TL</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, Johns Hopkins University, Baltimore, Maryland, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rao</LastName>
<ForeName>Lekha M</ForeName>
<Initials>LM</Initials>
</Author>
<Author ValidYN="Y"><LastName>Hess</LastName>
<ForeName>Ellen J</ForeName>
<Initials>EJ</Initials>
</Author>
<Author ValidYN="Y"><LastName>Jinnah</LastName>
<ForeName>H A</ForeName>
<Initials>HA</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>F32 NS52040</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R01 NS033592</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R01 NS033592-12</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R01 NS040470</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R01 NS040470-08</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R01 NS33592</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R01 NS40470</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R21 NS061349</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R21 NS061349-01A2</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Mov Disord</MedlineTA>
<NlmUniqueID>8610688</NlmUniqueID>
<ISSNLinking>0885-3185</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Dev Med Child Neurol. 2002 Jul;44(7):490-3</RefSource>
<PMID Version="1">12162387</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Pharmacol Biochem Behav. 2002 Oct;73(3):631-7</RefSource>
<PMID Version="1">12151038</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Cell Mol Neurobiol. 2002 Apr;22(2):103-20</RefSource>
<PMID Version="1">12363194</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2003 Mar;18(3):303-12</RefSource>
<PMID Version="1">12621634</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Brain Dev. 2003 Sep;25(6):401-5</RefSource>
<PMID Version="1">12907273</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Neuroscience. 2004;127(3):785-96</RefSource>
<PMID Version="1">15283975</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Exp Neurol. 1979 Dec;66(3):577-86</RefSource>
<PMID Version="1">488238</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann Neurol. 1995 Oct;38(4):571-9</RefSource>
<PMID Version="1">7574453</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Cell. 1996 Nov 1;87(3):543-52</RefSource>
<PMID Version="1">8898206</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Cell. 1996 Nov 15;87(4):607-17</RefSource>
<PMID Version="1">8929530</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Cell. 1997 Feb 7;88(3):385-92</RefSource>
<PMID Version="1">9039265</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mamm Genome. 1997 Feb;8(2):113-20</RefSource>
<PMID Version="1">9060410</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 1997 Oct;61(4):889-98</RefSource>
<PMID Version="1">9382100</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Hum Mol Genet. 1997 Oct;6(11):1973-8</RefSource>
<PMID Version="1">9302278</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mol Pharmacol. 1999 Jan;55(1):23-31</RefSource>
<PMID Version="1">9882694</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann Neurol. 1999 Mar;45(3):344-52</RefSource>
<PMID Version="1">10072049</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Neurol. 1999 Feb;246(2):120-6</RefSource>
<PMID Version="1">10195407</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Neurol. 1999 Mar;246(3):149-55</RefSource>
<PMID Version="1">10323309</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 1999 May;14(3):448-55</RefSource>
<PMID Version="1">10348468</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Neurology. 1999 Jul 13;53(1):3-4</RefSource>
<PMID Version="1">10408526</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Arch Neurol. 2005 Feb;62(2):314-6</RefSource>
<PMID Version="1">15710862</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Neurosci. 2005 Apr 20;25(16):4141-5</RefSource>
<PMID Version="1">15843617</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Neurobiol Dis. 2005 Nov;20(2):227-32</RefSource>
<PMID Version="1">16242631</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Brain Res. 2007 Feb 16;1133(1):168-77</RefSource>
<PMID Version="1">17196942</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Neurobiol Dis. 2007 Sep;27(3):249-57</RefSource>
<PMID Version="1">17561408</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Genes Brain Behav. 2007 Nov;6(8):717-27</RefSource>
<PMID Version="1">17376154</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Neurobiol Aging. 2008 Nov;29(11):1733-43</RefSource>
<PMID Version="1">17513018</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):15245-50</RefSource>
<PMID Version="1">10611370</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2000 May;15(3):429-33</RefSource>
<PMID Version="1">10830404</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2000 May;15(3):542-51</RefSource>
<PMID Version="1">10830422</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Neurosci. 2001 Feb 15;21(4):1169-78</RefSource>
<PMID Version="1">11160387</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>FASEB J. 2001 May;15(7):1288-90</RefSource>
<PMID Version="1">11344116</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Epilepsia. 2001;42 Suppl 3:36-41</RefSource>
<PMID Version="1">11520321</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2001 Sep 8;358(9284):801-7</RefSource>
<PMID Version="1">11564488</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Neurosci. 2002 Sep 15;22(18):8193-200</RefSource>
<PMID Version="1">12223573</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000367">Age Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001522">Behavior, Animal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002819">Chorea</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D004195">Disease Models, Animal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D051379">Mice</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008810">Mice, Inbred C57BL</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008818">Mice, Neurologic Mutants</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012720">Severity of Illness Index</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<OtherID Source="NLM">NIHMS132080</OtherID>
<OtherID Source="NLM">PMC2887756</OtherID>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2007</Year>
<Month>11</Month>
<Day>14</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2008</Year>
<Month>5</Month>
<Day>9</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2007</Year>
<Month>11</Month>
<Day>14</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="doi">10.1002/mds.21829</ArticleId>
<ArticleId IdType="pubmed">17999434</ArticleId>
<ArticleId IdType="pmc">PMC2887756</ArticleId>
<ArticleId IdType="mid">NIHMS132080</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002437 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 002437 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= PubMed |étape= Curation |type= RBID |clé= pubmed:17999434 |texte= Paroxysmal dyskinesias in mice. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:17999434" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \ | NlmPubMed2Wicri -a MovDisordV3
![]() | This area was generated with Dilib version V0.6.23. | ![]() |