Trihexyphenidyl for acute life-threatening episodes due to a dystonic movement disorder in Rett syndrome.
Identifieur interne : 001A31 ( PubMed/Curation ); précédent : 001A30; suivant : 001A32Trihexyphenidyl for acute life-threatening episodes due to a dystonic movement disorder in Rett syndrome.
Auteurs : Artemis D. Gika [Royaume-Uni] ; Elaine Hughes ; Sushma Goyal ; Matthew Sparkes ; Jean-Pierre LinSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2010.
English descriptors
- KwdEn :
- Adolescent, Antiparkinson Agents (therapeutic use), Child, Dystonic Disorders (drug therapy), Dystonic Disorders (etiology), Electrocardiography (methods), Electroencephalography (methods), Electromyography (methods), Female, Humans, Rett Syndrome (complications), Trihexyphenidyl (therapeutic use), Video Recording (methods), Young Adult.
- MESH :
- chemical , therapeutic use : Antiparkinson Agents, Trihexyphenidyl.
- complications : Rett Syndrome.
- drug therapy : Dystonic Disorders.
- etiology : Dystonic Disorders.
- methods : Electrocardiography, Electroencephalography, Electromyography, Video Recording.
- Adolescent, Child, Female, Humans, Young Adult.
Abstract
In Rett syndrome (RS), acute life-threatening episodes (ALTEs) are usually attributed to epilepsy or autonomic dysfunction but they can represent a movement disorder (MD). We describe three girls with RS who experienced ALTEs from an early age. These were long considered epileptic until video-EEG in Patients 1 and 3 revealed their non-epileptic nature. A primary dystonic mechanism was suspected and Patients 1 and 2 were treated with Trihexyphenidyl with significantly reduced frequency of the ALTEs. Patient 3 died before Trihexyphenidyl was tried. Trihexyphenidyl in RS patients with similar presentations can modify the dystonia and prevent ALTEs.
DOI: 10.1002/mds.22926
PubMed: 20063434
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001A31
Links to Exploration step
pubmed:20063434Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Trihexyphenidyl for acute life-threatening episodes due to a dystonic movement disorder in Rett syndrome.</title><author><name sortKey="Gika, Artemis D" sort="Gika, Artemis D" uniqKey="Gika A" first="Artemis D" last="Gika">Artemis D. Gika</name><affiliation wicri:level="1"><nlm:affiliation>Department of Paediatric Neurology, Evelina Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK. adgika@doctors.org.uk</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Paediatric Neurology, Evelina Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London</wicri:regionArea></affiliation></author><author><name sortKey="Hughes, Elaine" sort="Hughes, Elaine" uniqKey="Hughes E" first="Elaine" last="Hughes">Elaine Hughes</name></author><author><name sortKey="Goyal, Sushma" sort="Goyal, Sushma" uniqKey="Goyal S" first="Sushma" last="Goyal">Sushma Goyal</name></author><author><name sortKey="Sparkes, Matthew" sort="Sparkes, Matthew" uniqKey="Sparkes M" first="Matthew" last="Sparkes">Matthew Sparkes</name></author><author><name sortKey="Lin, Jean Pierre" sort="Lin, Jean Pierre" uniqKey="Lin J" first="Jean-Pierre" last="Lin">Jean-Pierre Lin</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="doi">10.1002/mds.22926</idno><idno type="RBID">pubmed:20063434</idno><idno type="pmid">20063434</idno><idno type="wicri:Area/PubMed/Corpus">001A31</idno><idno type="wicri:Area/PubMed/Curation">001A31</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Trihexyphenidyl for acute life-threatening episodes due to a dystonic movement disorder in Rett syndrome.</title><author><name sortKey="Gika, Artemis D" sort="Gika, Artemis D" uniqKey="Gika A" first="Artemis D" last="Gika">Artemis D. Gika</name><affiliation wicri:level="1"><nlm:affiliation>Department of Paediatric Neurology, Evelina Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK. adgika@doctors.org.uk</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Paediatric Neurology, Evelina Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London</wicri:regionArea></affiliation></author><author><name sortKey="Hughes, Elaine" sort="Hughes, Elaine" uniqKey="Hughes E" first="Elaine" last="Hughes">Elaine Hughes</name></author><author><name sortKey="Goyal, Sushma" sort="Goyal, Sushma" uniqKey="Goyal S" first="Sushma" last="Goyal">Sushma Goyal</name></author><author><name sortKey="Sparkes, Matthew" sort="Sparkes, Matthew" uniqKey="Sparkes M" first="Matthew" last="Sparkes">Matthew Sparkes</name></author><author><name sortKey="Lin, Jean Pierre" sort="Lin, Jean Pierre" uniqKey="Lin J" first="Jean-Pierre" last="Lin">Jean-Pierre Lin</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Antiparkinson Agents (therapeutic use)</term><term>Child</term><term>Dystonic Disorders (drug therapy)</term><term>Dystonic Disorders (etiology)</term><term>Electrocardiography (methods)</term><term>Electroencephalography (methods)</term><term>Electromyography (methods)</term><term>Female</term><term>Humans</term><term>Rett Syndrome (complications)</term><term>Trihexyphenidyl (therapeutic use)</term><term>Video Recording (methods)</term><term>Young Adult</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term><term>Trihexyphenidyl</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Rett Syndrome</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Dystonic Disorders</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dystonic Disorders</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Electrocardiography</term><term>Electroencephalography</term><term>Electromyography</term><term>Video Recording</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Child</term><term>Female</term><term>Humans</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In Rett syndrome (RS), acute life-threatening episodes (ALTEs) are usually attributed to epilepsy or autonomic dysfunction but they can represent a movement disorder (MD). We describe three girls with RS who experienced ALTEs from an early age. These were long considered epileptic until video-EEG in Patients 1 and 3 revealed their non-epileptic nature. A primary dystonic mechanism was suspected and Patients 1 and 2 were treated with Trihexyphenidyl with significantly reduced frequency of the ALTEs. Patient 3 died before Trihexyphenidyl was tried. Trihexyphenidyl in RS patients with similar presentations can modify the dystonia and prevent ALTEs.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">20063434</PMID><DateCreated><Year>2010</Year><Month>03</Month><Day>03</Day></DateCreated><DateCompleted><Year>2010</Year><Month>06</Month><Day>02</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN><JournalIssue CitedMedium="Internet"><Volume>25</Volume><Issue>3</Issue><PubDate><Year>2010</Year><Month>Feb</Month><Day>15</Day></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Trihexyphenidyl for acute life-threatening episodes due to a dystonic movement disorder in Rett syndrome.</ArticleTitle><Pagination><MedlinePgn>385-9</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.22926</ELocationID><Abstract><AbstractText>In Rett syndrome (RS), acute life-threatening episodes (ALTEs) are usually attributed to epilepsy or autonomic dysfunction but they can represent a movement disorder (MD). We describe three girls with RS who experienced ALTEs from an early age. These were long considered epileptic until video-EEG in Patients 1 and 3 revealed their non-epileptic nature. A primary dystonic mechanism was suspected and Patients 1 and 2 were treated with Trihexyphenidyl with significantly reduced frequency of the ALTEs. Patient 3 died before Trihexyphenidyl was tried. Trihexyphenidyl in RS patients with similar presentations can modify the dystonia and prevent ALTEs.</AbstractText><CopyrightInformation>(c) 2009 Movement Disorder Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gika</LastName><ForeName>Artemis D</ForeName><Initials>AD</Initials><AffiliationInfo><Affiliation>Department of Paediatric Neurology, Evelina Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK. adgika@doctors.org.uk</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hughes</LastName><ForeName>Elaine</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Goyal</LastName><ForeName>Sushma</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Sparkes</LastName><ForeName>Matthew</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Lin</LastName><ForeName>Jean-Pierre</ForeName><Initials>JP</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000978">Antiparkinson Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>6RC5V8B7PO</RegistryNumber><NameOfSubstance UI="D014282">Trihexyphenidyl</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000293">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000978">Antiparkinson Agents</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D002648">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D020821">Dystonic Disorders</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000188">drug therapy</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000209">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004562">Electrocardiography</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004569">Electroencephalography</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004576">Electromyography</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D015518">Rett Syndrome</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000150">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014282">Trihexyphenidyl</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014741">Video Recording</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D055815">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2010</Year><Month>1</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2010</Year><Month>1</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>6</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="doi">10.1002/mds.22926</ArticleId><ArticleId IdType="pubmed">20063434</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001A31 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 001A31 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:20063434
|texte= Trihexyphenidyl for acute life-threatening episodes due to a dystonic movement disorder in Rett syndrome.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:20063434" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |