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Higher serum uric acid associated with decreased Parkinson's disease prevalence in a large community-based survey.

Identifieur interne : 001873 ( PubMed/Curation ); précédent : 001872; suivant : 001874

Higher serum uric acid associated with decreased Parkinson's disease prevalence in a large community-based survey.

Auteurs : Andrea Winquist [États-Unis] ; Kyle Steenland ; Anoop Shankar

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2010.

RBID : pubmed:20310031

English descriptors

KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Parkinson Disease (blood), Parkinson Disease (diagnosis), Parkinson Disease (epidemiology), Prevalence, Questionnaires, Residence Characteristics, Uric Acid (blood), Young Adult.
MESH :
- chemical , blood : Uric Acid.
- blood : Parkinson Disease.
- diagnosis : Parkinson Disease.
- epidemiology : Parkinson Disease.
- Adolescent, Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prevalence, Questionnaires, Residence Characteristics, Young Adult.

Abstract

A large community-based cross-sectional survey provided an opportunity to evaluate a previously reported association between Parkinson's disease (PD) and low serum uric acid (UA) levels in this population. The association between a self-reported PD diagnosis with treatment (n = 59) and serum UA level was examined using logistic and linear regression models, controlling for key covariates. In adjusted models, participants with UA levels at or above the median had a significantly lower odds of reporting PD with treatment compared with those with lower UA levels (OR 0.33, 95% CI 0.19-0.60, P = 0.0002). This association was observed for both men and women. The mean UA level among participants reporting PD with treatment was 0.78 mg/dl lower than the mean UA level among those not reporting PD (P
DOI: 10.1002/mds.23070
PubMed: 20310031

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pubmed:20310031

Le document en format XML

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<author><name sortKey="Winquist, Andrea" sort="Winquist, Andrea" uniqKey="Winquist A" first="Andrea" last="Winquist">Andrea Winquist</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA. awinqui@sph.emory.edu</nlm:affiliation>
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<wicri:regionArea>Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322</wicri:regionArea>
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<author><name sortKey="Steenland, Kyle" sort="Steenland, Kyle" uniqKey="Steenland K" first="Kyle" last="Steenland">Kyle Steenland</name>
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<author><name sortKey="Shankar, Anoop" sort="Shankar, Anoop" uniqKey="Shankar A" first="Anoop" last="Shankar">Anoop Shankar</name>
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<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (blood)</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (epidemiology)</term>
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<term>Questionnaires</term>
<term>Residence Characteristics</term>
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<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Uric Acid</term>
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<front><div type="abstract" xml:lang="en">A large community-based cross-sectional survey provided an opportunity to evaluate a previously reported association between Parkinson's disease (PD) and low serum uric acid (UA) levels in this population. The association between a self-reported PD diagnosis with treatment (n = 59) and serum UA level was examined using logistic and linear regression models, controlling for key covariates. In adjusted models, participants with UA levels at or above the median had a significantly lower odds of reporting PD with treatment compared with those with lower UA levels (OR 0.33, 95% CI 0.19-0.60, P = 0.0002). This association was observed for both men and women. The mean UA level among participants reporting PD with treatment was 0.78 mg/dl lower than the mean UA level among those not reporting PD (P </div>
</front>
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<Month>05</Month>
<Day>12</Day>
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<DateCompleted><Year>2010</Year>
<Month>08</Month>
<Day>17</Day>
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<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<Abstract><AbstractText>A large community-based cross-sectional survey provided an opportunity to evaluate a previously reported association between Parkinson's disease (PD) and low serum uric acid (UA) levels in this population. The association between a self-reported PD diagnosis with treatment (n = 59) and serum UA level was examined using logistic and linear regression models, controlling for key covariates. In adjusted models, participants with UA levels at or above the median had a significantly lower odds of reporting PD with treatment compared with those with lower UA levels (OR 0.33, 95% CI 0.19-0.60, P = 0.0002). This association was observed for both men and women. The mean UA level among participants reporting PD with treatment was 0.78 mg/dl lower than the mean UA level among those not reporting PD (P </AbstractText>
<CopyrightInformation>(c) 2010 Movement Disorder Society.</CopyrightInformation>
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<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D011795">Questionnaires</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012111">Residence Characteristics</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D014527">Uric Acid</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000097">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D055815">Young Adult</DescriptorName>
</MeshHeading>
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Movement Disorders (revue)

Higher serum uric acid associated with decreased Parkinson's disease prevalence in a large community-based survey.

Higher serum uric acid associated with decreased Parkinson's disease prevalence in a large community-based survey.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki