Rapidly progressive diffuse Lewy body disease.
Identifieur interne : 001302 ( PubMed/Curation ); précédent : 001301; suivant : 001303Rapidly progressive diffuse Lewy body disease.
Auteurs : Carles Gaig [Espagne] ; Francesc Valldeoriola ; Ellen Gelpi ; Mario Ezquerra ; Sara Llufriu ; Mariateresa Buongiorno ; Maria Jesús Rey ; Maria Jose Martí ; Francesc Graus ; Eduardo TolosaSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2011.
English descriptors
- KwdEn :
- Aged, Brain (pathology), Delirium (etiology), Delirium (pathology), Delirium (physiopathology), Disease Progression, Fatal Outcome, Female, Hallucinations (etiology), Hallucinations (pathology), Hallucinations (physiopathology), Humans, Lewy Body Disease (complications), Lewy Body Disease (pathology), Lewy Body Disease (physiopathology), Male, Medical Records, Myoclonus (etiology), Myoclonus (pathology), Myoclonus (physiopathology), Parkinsonian Disorders (etiology), Parkinsonian Disorders (pathology), Parkinsonian Disorders (physiopathology), Severity of Illness Index.
- MESH :
- complications : Lewy Body Disease.
- etiology : Delirium, Hallucinations, Myoclonus, Parkinsonian Disorders.
- pathology : Brain, Delirium, Hallucinations, Lewy Body Disease, Myoclonus, Parkinsonian Disorders.
- physiopathology : Delirium, Hallucinations, Lewy Body Disease, Myoclonus, Parkinsonian Disorders.
- Aged, Disease Progression, Fatal Outcome, Female, Humans, Male, Medical Records, Severity of Illness Index.
Abstract
Lewy body syndromes (mainly Parkinson's disease and dementia with Lewy bodies) share many clinical features and usually have a slowly progressive course. Some patients may show rapid symptoms progression.
DOI: 10.1002/mds.23506
PubMed: 21484863
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sortKey="Llufriu, Sara" sort="Llufriu, Sara" uniqKey="Llufriu S" first="Sara" last="Llufriu">Sara Llufriu</name></author><author><name sortKey="Buongiorno, Mariateresa" sort="Buongiorno, Mariateresa" uniqKey="Buongiorno M" first="Mariateresa" last="Buongiorno">Mariateresa Buongiorno</name></author><author><name sortKey="Rey, Maria Jesus" sort="Rey, Maria Jesus" uniqKey="Rey M" first="Maria Jesús" last="Rey">Maria Jesús Rey</name></author><author><name sortKey="Marti, Maria Jose" sort="Marti, Maria Jose" uniqKey="Marti M" first="Maria Jose" last="Martí">Maria Jose Martí</name></author><author><name sortKey="Graus, Francesc" sort="Graus, Francesc" uniqKey="Graus F" first="Francesc" last="Graus">Francesc Graus</name></author><author><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2011">2011</date><idno type="doi">10.1002/mds.23506</idno><idno type="RBID">pubmed:21484863</idno><idno type="pmid">21484863</idno><idno type="wicri:Area/PubMed/Corpus">001302</idno><idno type="wicri:Area/PubMed/Curation">001302</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Rapidly progressive diffuse Lewy body disease.</title><author><name sortKey="Gaig, Carles" sort="Gaig, Carles" uniqKey="Gaig C" first="Carles" last="Gaig">Carles Gaig</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Service, Hospital Clínic of Barcelona, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Neurology Service, Hospital Clínic of Barcelona, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Valldeoriola, Francesc" sort="Valldeoriola, Francesc" uniqKey="Valldeoriola F" first="Francesc" last="Valldeoriola">Francesc Valldeoriola</name></author><author><name sortKey="Gelpi, Ellen" sort="Gelpi, Ellen" uniqKey="Gelpi E" first="Ellen" last="Gelpi">Ellen Gelpi</name></author><author><name sortKey="Ezquerra, Mario" sort="Ezquerra, Mario" uniqKey="Ezquerra M" first="Mario" last="Ezquerra">Mario Ezquerra</name></author><author><name sortKey="Llufriu, Sara" sort="Llufriu, Sara" uniqKey="Llufriu S" first="Sara" last="Llufriu">Sara Llufriu</name></author><author><name sortKey="Buongiorno, Mariateresa" sort="Buongiorno, Mariateresa" uniqKey="Buongiorno M" first="Mariateresa" last="Buongiorno">Mariateresa Buongiorno</name></author><author><name sortKey="Rey, Maria Jesus" sort="Rey, Maria Jesus" uniqKey="Rey M" first="Maria Jesús" last="Rey">Maria Jesús Rey</name></author><author><name sortKey="Marti, Maria Jose" sort="Marti, Maria Jose" uniqKey="Marti M" first="Maria Jose" last="Martí">Maria Jose Martí</name></author><author><name sortKey="Graus, Francesc" sort="Graus, Francesc" uniqKey="Graus F" first="Francesc" last="Graus">Francesc Graus</name></author><author><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2011" type="published">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Brain (pathology)</term><term>Delirium (etiology)</term><term>Delirium (pathology)</term><term>Delirium (physiopathology)</term><term>Disease Progression</term><term>Fatal Outcome</term><term>Female</term><term>Hallucinations (etiology)</term><term>Hallucinations (pathology)</term><term>Hallucinations (physiopathology)</term><term>Humans</term><term>Lewy Body Disease (complications)</term><term>Lewy Body Disease (pathology)</term><term>Lewy Body Disease (physiopathology)</term><term>Male</term><term>Medical Records</term><term>Myoclonus (etiology)</term><term>Myoclonus (pathology)</term><term>Myoclonus (physiopathology)</term><term>Parkinsonian Disorders (etiology)</term><term>Parkinsonian Disorders (pathology)</term><term>Parkinsonian Disorders (physiopathology)</term><term>Severity of Illness Index</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Lewy Body Disease</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Delirium</term><term>Hallucinations</term><term>Myoclonus</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term><term>Delirium</term><term>Hallucinations</term><term>Lewy Body Disease</term><term>Myoclonus</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Delirium</term><term>Hallucinations</term><term>Lewy Body Disease</term><term>Myoclonus</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Disease Progression</term><term>Fatal Outcome</term><term>Female</term><term>Humans</term><term>Male</term><term>Medical Records</term><term>Severity of Illness Index</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lewy body syndromes (mainly Parkinson's disease and dementia with Lewy bodies) share many clinical features and usually have a slowly progressive course. Some patients may show rapid symptoms progression.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">21484863</PMID><DateCreated><Year>2011</Year><Month>06</Month><Day>21</Day></DateCreated><DateCompleted><Year>2011</Year><Month>11</Month><Day>02</Day></DateCompleted><DateRevised><Year>2012</Year><Month>01</Month><Day>24</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN><JournalIssue CitedMedium="Internet"><Volume>26</Volume><Issue>7</Issue><PubDate><Year>2011</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Rapidly progressive diffuse Lewy body disease.</ArticleTitle><Pagination><MedlinePgn>1316-23</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.23506</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Lewy body syndromes (mainly Parkinson's disease and dementia with Lewy bodies) share many clinical features and usually have a slowly progressive course. Some patients may show rapid symptoms progression.</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate clinical and neuropathological features of patients with a rapidly progressive diffuse Lewy Body disease.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Review clinical records and pathological findings of 6 cases with diffuse Lewy Body disease and rapid disease progression (less than 18 months before death).</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Mean age at disease onset was 72.5 years, and mean disease duration was 9 months. Onset consisted of delirium in 3 patients and rapidly progressive dementia in the other three. All cases presented visual hallucinations and delusions; cognitive symptoms were fluctuating in two, parkinsonism occurred in four, and myoclonus in three. Brain MRI did not show cortical or basal ganglia hyperintensities. Periodic sharp waves were absent on EEG. 14.3.3 protein in CSF was negative. Myocardial (123) I-metaiodo-benzyl-guanidine SPECT showed marked reduction in tracer uptake in the 2 patients tested. Neuropathological studies did not identify any particular feature that could differentiate rapidly progressive diffuse Lewy body disease from classical diffuse Lewy body disease.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Diffuse Lewy body disease is a possible cause of rapidly progressive dementia and should be included in the differential diagnosis of confusional states of undetermined cause. In patients with rapidly progressive dementia, the presence of fluctuating cognition, parkinsonism, hallucinations, delusions, or severe dysautonomia, should raise the suspicion of diffuse Lewy body disease. Neuroimaging studies such as (123) I-metaiodo-benzyl-guanidine myocardial scintigraphy may support the clinical diagnosis of diffuse Lewy body disease. © 2011 Movement Disorder Society.</AbstractText><CopyrightInformation>Copyright © 2011 Movement Disorder Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gaig</LastName><ForeName>Carles</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Neurology Service, Hospital Clínic of Barcelona, Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Valldeoriola</LastName><ForeName>Francesc</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Gelpi</LastName><ForeName>Ellen</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Ezquerra</LastName><ForeName>Mario</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Llufriu</LastName><ForeName>Sara</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Buongiorno</LastName><ForeName>Mariateresa</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Rey</LastName><ForeName>Maria Jesús</ForeName><Initials>MJ</Initials></Author><Author ValidYN="Y"><LastName>Martí</LastName><ForeName>Maria Jose</ForeName><Initials>MJ</Initials></Author><Author ValidYN="Y"><LastName>Graus</LastName><ForeName>Francesc</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Tolosa</LastName><ForeName>Eduardo</ForeName><Initials>E</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2011</Year><Month>04</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Mov Disord. 2011 Dec;26(14):2584-5; author reply 2585</RefSource><PMID Version="1">22038930</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D001921">Brain</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D003693">Delirium</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D018450">Disease Progression</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D017809">Fatal Outcome</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006212">Hallucinations</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D020961">Lewy Body Disease</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008499">Medical Records</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009207">Myoclonus</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D020734">Parkinsonian Disorders</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D012720">Severity of Illness Index</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2010</Year><Month>8</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2010</Year><Month>10</Month><Day>6</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2010</Year><Month>10</Month><Day>7</Day></PubMedPubDate><PubMedPubDate PubStatus="aheadofprint"><Year>2011</Year><Month>4</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2011</Year><Month>4</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2011</Year><Month>4</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2011</Year><Month>11</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="doi">10.1002/mds.23506</ArticleId><ArticleId IdType="pubmed">21484863</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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