Movement Disorders (revue)

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Modulation of dysarthropneumophonia by low-frequency STN DBS in advanced Parkinson's disease.

Identifieur interne : 001275 ( PubMed/Curation ); précédent : 001274; suivant : 001276

Modulation of dysarthropneumophonia by low-frequency STN DBS in advanced Parkinson's disease.

Auteurs : Caroline Moreau [France] ; Odile Pennel-Ployart ; Serge Pinto ; Audrey Plachez ; Agnes Annic ; François Viallet ; Alain Destée ; Luc Defebvre

Source :

RBID : pubmed:21506146

English descriptors

Abstract

Parkinsonian dysarthria (as typically characterized by hypophonia, monotony of pitch, and rhythm abnormalities) is often accompanied by gait disturbances. The long-term effect of subthalamic nucleus deep brain stimulation (STN DBS) on dysarthria remains unclear.

DOI: 10.1002/mds.23538
PubMed: 21506146

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Le document en format XML

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<title xml:lang="en">Modulation of dysarthropneumophonia by low-frequency STN DBS in advanced Parkinson's disease.</title>
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<name sortKey="Moreau, Caroline" sort="Moreau, Caroline" uniqKey="Moreau C" first="Caroline" last="Moreau">Caroline Moreau</name>
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<nlm:affiliation>Service de neurologie et pathologie du mouvement, Université Lille Nord de France, France. caroline.moreau@chru-lille.fr</nlm:affiliation>
<country xml:lang="fr">France</country>
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<name sortKey="Pennel Ployart, Odile" sort="Pennel Ployart, Odile" uniqKey="Pennel Ployart O" first="Odile" last="Pennel-Ployart">Odile Pennel-Ployart</name>
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<name sortKey="Pinto, Serge" sort="Pinto, Serge" uniqKey="Pinto S" first="Serge" last="Pinto">Serge Pinto</name>
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<name sortKey="Plachez, Audrey" sort="Plachez, Audrey" uniqKey="Plachez A" first="Audrey" last="Plachez">Audrey Plachez</name>
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<name sortKey="Annic, Agnes" sort="Annic, Agnes" uniqKey="Annic A" first="Agnes" last="Annic">Agnes Annic</name>
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<name sortKey="Viallet, Francois" sort="Viallet, Francois" uniqKey="Viallet F" first="François" last="Viallet">François Viallet</name>
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<name sortKey="Destee, Alain" sort="Destee, Alain" uniqKey="Destee A" first="Alain" last="Destée">Alain Destée</name>
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<name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name>
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<title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Male</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (therapy)</term>
<term>Severity of Illness Index</term>
<term>Speech Disorders (etiology)</term>
<term>Speech Disorders (therapy)</term>
<term>Subthalamic Nucleus (physiology)</term>
<term>Voice Disorders (etiology)</term>
<term>Voice Disorders (therapy)</term>
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<term>Parkinson Disease</term>
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<term>Voice Disorders</term>
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<div type="abstract" xml:lang="en">Parkinsonian dysarthria (as typically characterized by hypophonia, monotony of pitch, and rhythm abnormalities) is often accompanied by gait disturbances. The long-term effect of subthalamic nucleus deep brain stimulation (STN DBS) on dysarthria remains unclear.</div>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Parkinsonian dysarthria (as typically characterized by hypophonia, monotony of pitch, and rhythm abnormalities) is often accompanied by gait disturbances. The long-term effect of subthalamic nucleus deep brain stimulation (STN DBS) on dysarthria remains unclear.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Given STN DBS's known improvement of gait disorders, we analyzed speech intelligibility and aerodynamic and acoustic parameters in 11 advanced PD patients in three double-blind, randomized conditions: "defined Off," 60 Hz STN DBS and 130 Hz STN DBS.</AbstractText>
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<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Chronic treatment with low-frequency STN DBS may have a beneficial impact on dysarthropneumophonia, even in advanced PD patients.</AbstractText>
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