Movement Disorders (revue)

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The prevalence and clinical characteristics of punding in Parkinson's disease.

Identifieur interne : 001146 ( PubMed/Curation ); précédent : 001145; suivant : 001147

The prevalence and clinical characteristics of punding in Parkinson's disease.

Auteurs : Ashley H. Spencer [Royaume-Uni] ; Hugh Rickards ; Alfonso Fasano ; Andrea E. Cavanna

Source :

RBID : pubmed:21648123

English descriptors

Abstract

Punding (the display of stereotyped, repetitive behaviors) is a relatively recently discovered feature of Parkinson's disease (PD). Little is known about the prevalence and clinical characteristics of punding in PD.

PubMed: 21648123

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pubmed:21648123

Le document en format XML

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<nlm:affiliation>Department of Neuropsychiatry, University of Birmingham and BSMHFT, Birmingham, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Neuropsychiatry, University of Birmingham and BSMHFT, Birmingham</wicri:regionArea>
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<name sortKey="Rickards, Hugh" sort="Rickards, Hugh" uniqKey="Rickards H" first="Hugh" last="Rickards">Hugh Rickards</name>
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<name sortKey="Fasano, Alfonso" sort="Fasano, Alfonso" uniqKey="Fasano A" first="Alfonso" last="Fasano">Alfonso Fasano</name>
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<name sortKey="Cavanna, Andrea E" sort="Cavanna, Andrea E" uniqKey="Cavanna A" first="Andrea E" last="Cavanna">Andrea E. Cavanna</name>
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<title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Dopamine Agents (therapeutic use)</term>
<term>Female</term>
<term>Humans</term>
<term>Impulse Control Disorders (drug therapy)</term>
<term>Impulse Control Disorders (epidemiology)</term>
<term>Impulse Control Disorders (etiology)</term>
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<term>Parkinson Disease (complications)</term>
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<div type="abstract" xml:lang="en">Punding (the display of stereotyped, repetitive behaviors) is a relatively recently discovered feature of Parkinson's disease (PD). Little is known about the prevalence and clinical characteristics of punding in PD.</div>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Punding (the display of stereotyped, repetitive behaviors) is a relatively recently discovered feature of Parkinson's disease (PD). Little is known about the prevalence and clinical characteristics of punding in PD.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">In this review, four large scientific databases were comprehensively searched for literature in relation to punding prevalence and clinical correlates in the context of PD.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Prevalence was found to vary greatly (between 0.34 to 14%), although there were large disparities in study populations, assessment methods, and criteria. We observed an association between punding, dopaminergic medications, and impulse control disorder. Other characteristics, which may be more common among punders, include a higher severity of dyskinesia, younger age of disease onset, longer disease duration, and male gender.</AbstractText>
<AbstractText Label="DISCUSSION" NlmCategory="CONCLUSIONS">More research in large clinical datasets is required in many areas before conclusions are drawn. The pathophysiology behind the punding phenomenon is also poorly understood at present, rendering it difficult to develop targeted therapy. The current mainstay of treatment is the reduction in the dose of dopaminergic medications, the evidence for other suggested therapies being purely empirical.</AbstractText>
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