MovDisordV3, PubMed, Curation, bibRecord, 000481

Changes in motor cortical excitability in patients with Sydenham's chorea.

Identifieur interne : 000481 ( PubMed/Curation ); précédent : 000480; suivant : 000482

Changes in motor cortical excitability in patients with Sydenham's chorea.

Auteurs : Eman M. Khedr [Égypte] ; Mohamed A. Ahmed ; Anwar M. Ali ; Reda Badry ; John C. Rothwell

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.

RBID : pubmed:24909435

English descriptors

KwdEn :
- Adolescent, Adult, Child, Chorea (diagnosis), Chorea (physiopathology), Chorea (therapy), Evoked Potentials, Motor (physiology), Female, Humans, Huntington Disease (complications), Male, Motor Cortex (physiopathology), Psychomotor Agitation (therapy), Transcranial Magnetic Stimulation (methods), Young Adult.
MESH :
- complications : Huntington Disease.
- diagnosis : Chorea.
- methods : Transcranial Magnetic Stimulation.
- physiology : Evoked Potentials, Motor.
- physiopathology : Chorea, Motor Cortex.
- therapy : Chorea, Psychomotor Agitation.
- Adolescent, Adult, Child, Female, Humans, Male, Young Adult.

Abstract

The neurophysiological characteristics of motor cortex have been well characterized in patients with Huntington's disease. We present the first data on cortical excitability in patients with Sydenham's chorea.

DOI: 10.1002/mds.25928
PubMed: 24909435

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Le document en format XML

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<author><name sortKey="Khedr, Eman M" sort="Khedr, Eman M" uniqKey="Khedr E" first="Eman M" last="Khedr">Eman M. Khedr</name>
<affiliation wicri:level="1"><nlm:affiliation>Departments of Neuropsychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Departments of Neuropsychiatry, Faculty of Medicine, Assiut University, Assiut</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ahmed, Mohamed A" sort="Ahmed, Mohamed A" uniqKey="Ahmed M" first="Mohamed A" last="Ahmed">Mohamed A. Ahmed</name>
</author>
<author><name sortKey="Ali, Anwar M" sort="Ali, Anwar M" uniqKey="Ali A" first="Anwar M" last="Ali">Anwar M. Ali</name>
</author>
<author><name sortKey="Badry, Reda" sort="Badry, Reda" uniqKey="Badry R" first="Reda" last="Badry">Reda Badry</name>
</author>
<author><name sortKey="Rothwell, John C" sort="Rothwell, John C" uniqKey="Rothwell J" first="John C" last="Rothwell">John C. Rothwell</name>
</author>
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<date when="2015">2015</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Changes in motor cortical excitability in patients with Sydenham's chorea.</title>
<author><name sortKey="Khedr, Eman M" sort="Khedr, Eman M" uniqKey="Khedr E" first="Eman M" last="Khedr">Eman M. Khedr</name>
<affiliation wicri:level="1"><nlm:affiliation>Departments of Neuropsychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Departments of Neuropsychiatry, Faculty of Medicine, Assiut University, Assiut</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ahmed, Mohamed A" sort="Ahmed, Mohamed A" uniqKey="Ahmed M" first="Mohamed A" last="Ahmed">Mohamed A. Ahmed</name>
</author>
<author><name sortKey="Ali, Anwar M" sort="Ali, Anwar M" uniqKey="Ali A" first="Anwar M" last="Ali">Anwar M. Ali</name>
</author>
<author><name sortKey="Badry, Reda" sort="Badry, Reda" uniqKey="Badry R" first="Reda" last="Badry">Reda Badry</name>
</author>
<author><name sortKey="Rothwell, John C" sort="Rothwell, John C" uniqKey="Rothwell J" first="John C" last="Rothwell">John C. Rothwell</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2015" type="published">2015</date>
</imprint>
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</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Child</term>
<term>Chorea (diagnosis)</term>
<term>Chorea (physiopathology)</term>
<term>Chorea (therapy)</term>
<term>Evoked Potentials, Motor (physiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Huntington Disease (complications)</term>
<term>Male</term>
<term>Motor Cortex (physiopathology)</term>
<term>Psychomotor Agitation (therapy)</term>
<term>Transcranial Magnetic Stimulation (methods)</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Huntington Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Chorea</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Transcranial Magnetic Stimulation</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Evoked Potentials, Motor</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Chorea</term>
<term>Motor Cortex</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Chorea</term>
<term>Psychomotor Agitation</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Child</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Young Adult</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The neurophysiological characteristics of motor cortex have been well characterized in patients with Huntington's disease. We present the first data on cortical excitability in patients with Sydenham's chorea.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">24909435</PMID>
<DateCreated><Year>2015</Year>
<Month>02</Month>
<Day>04</Day>
</DateCreated>
<DateCompleted><Year>2015</Year>
<Month>10</Month>
<Day>22</Day>
</DateCompleted>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>30</Volume>
<Issue>2</Issue>
<PubDate><Year>2015</Year>
<Month>Feb</Month>
</PubDate>
</JournalIssue>
<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
</Journal>
<ArticleTitle>Changes in motor cortical excitability in patients with Sydenham's chorea.</ArticleTitle>
<Pagination><MedlinePgn>259-62</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.25928</ELocationID>
<Abstract><AbstractText Label="BACKGROUND AND PURPOSE" NlmCategory="OBJECTIVE">The neurophysiological characteristics of motor cortex have been well characterized in patients with Huntington's disease. We present the first data on cortical excitability in patients with Sydenham's chorea.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Motor cortex excitability was examined using transcranial magnetic stimulation in 16 patients in the early clinical stages of Sydenham's chorea and in 17 age- and sex-matched control subjects. Investigations included resting and active motor threshold, motor evoked potential, input-output curves, contralateral silent period, and transcallosal inhibition.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Resting and active motor threshold were significantly higher and motor evoked potentials were significantly smaller in patients in comparison with controls. The input-output curves were shallower in both hemispheres of patients with chorea compared with controls. No significant differences were seen in silent period or transcallosal inhibition duration.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Sydenham's chorea is characterized by reduced excitability of corticospinal output similar to that observed in Huntington's disease.</AbstractText>
<CopyrightInformation>© 2014 International Parkinson and Movement Disorder Society.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Khedr</LastName>
<ForeName>Eman M</ForeName>
<Initials>EM</Initials>
<AffiliationInfo><Affiliation>Departments of Neuropsychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ahmed</LastName>
<ForeName>Mohamed A</ForeName>
<Initials>MA</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ali</LastName>
<ForeName>Anwar M</ForeName>
<Initials>AM</Initials>
</Author>
<Author ValidYN="Y"><LastName>Badry</LastName>
<ForeName>Reda</ForeName>
<Initials>R</Initials>
</Author>
<Author ValidYN="Y"><LastName>Rothwell</LastName>
<ForeName>John C</ForeName>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
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<ArticleDate DateType="Electronic"><Year>2014</Year>
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<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Mov Disord</MedlineTA>
<NlmUniqueID>8610688</NlmUniqueID>
<ISSNLinking>0885-3185</ISSNLinking>
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<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000293">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002648">Child</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002819">Chorea</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D019054">Evoked Potentials, Motor</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName>
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<QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011595">Psychomotor Agitation</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000628">therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D050781">Transcranial Magnetic Stimulation</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D055815">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Sydenham's chorea</Keyword>
<Keyword MajorTopicYN="N">cortical excitability</Keyword>
<Keyword MajorTopicYN="N">cortical silent period</Keyword>
<Keyword MajorTopicYN="N">motor threshold</Keyword>
<Keyword MajorTopicYN="N">transcranial magnetic stimulation</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year>
<Month>12</Month>
<Day>23</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2014</Year>
<Month>4</Month>
<Day>10</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2014</Year>
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<PublicationStatus>ppublish</PublicationStatus>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Changes in motor cortical excitability in patients with Sydenham's chorea.

Changes in motor cortical excitability in patients with Sydenham's chorea.

Source :

English descriptors

Abstract

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