Movement Disorders (revue)

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Predictors of response to a cognitive behavioral intervention for impulse control behaviors in Parkinson's disease.

Identifieur interne : 000297 ( PubMed/Curation ); précédent : 000296; suivant : 000298

Predictors of response to a cognitive behavioral intervention for impulse control behaviors in Parkinson's disease.

Auteurs : David Okai [Royaume-Uni] ; Sally Askey-Jones ; Michael Samuel ; Anthony S. David ; Richard G. Brown

Source :

RBID : pubmed:25546340

Abstract

Limited trial evidence suggests that cognitive-behavioral therapy (CBT) may be effective in managing impulse control behavior (ICBs) in Parkinson's disease.

DOI: 10.1002/mds.26108
PubMed: 25546340

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Le document en format XML

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<name sortKey="Okai, David" sort="Okai, David" uniqKey="Okai D" first="David" last="Okai">David Okai</name>
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<nlm:affiliation>King's College London, Institute of Psychiatry, Psychology and Neuroscience, Section of Cognitive Neuropsychiatry, Department of Psychosis studies, London, United Kingdom; Oxford University Hospitals NHS Trust, Oxford, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>King's College London, Institute of Psychiatry, Psychology and Neuroscience, Section of Cognitive Neuropsychiatry, Department of Psychosis studies, London, United Kingdom; Oxford University Hospitals NHS Trust, Oxford</wicri:regionArea>
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<name sortKey="Samuel, Michael" sort="Samuel, Michael" uniqKey="Samuel M" first="Michael" last="Samuel">Michael Samuel</name>
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<title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Limited trial evidence suggests that cognitive-behavioral therapy (CBT) may be effective in managing impulse control behavior (ICBs) in Parkinson's disease.</AbstractText>
<AbstractText Label="AIMS" NlmCategory="OBJECTIVE">To examine predictors of outcome in trial, participants (N=42) receiving treatment immediately or after a waiting time.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Dependent variables were Clinical Global Impression of Change (CGI-C) and the Neuropsychiatric Inventory (NPI). Baseline demographic and clinical variables were independent variables.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Better CGI-C was predicted by fewer ICBs, taking a dopamine agonist, lower levodopa (l-dopa) equivalent dose (LEDD), higher social functioning, and lower NPI severity before treatment. Improvement on the NPI was predicted by lower LEDD, lower anxiety, lower baseline global clinical severity, and higher social functioning.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Patients with lower burden of ICBs and other psychiatric symptomatology, better social functioning, and lower dose of antiparkinsonian medication may benefit more from CBT. However, we cannot yet identify individual patients with sufficient confidence at this stage to target treatment.</AbstractText>
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