Movement Disorders (revue)

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Postneuroleptic laryngeal dyskinesias: a cause of upper airway obstructive syndrome improved by local injections of botulinum toxin.

Identifieur interne : 004C44 ( PubMed/Corpus ); précédent : 004C43; suivant : 004C45

Postneuroleptic laryngeal dyskinesias: a cause of upper airway obstructive syndrome improved by local injections of botulinum toxin.

Auteurs : A. Fève ; B. Angelard ; G. Fénelon ; M. Logak ; A. Guillard ; J. Lacau Saint-Guily

Source :

RBID : pubmed:8474494

English descriptors

Abstract

We report a case of laryngeal dyskinesia resulting in severe rest and exercise dyspnea. A 51-year-old man treated for 2 years with flupentixol, an incisive neuroleptic, developed severe dyspnea due to intermittent, rhythmic, and dystonic movements of the vocal cords and upper airway. Local injections of botulinum toxin resulted in spectacular regression of laryngeal spasms and major improvement in breathing. This case emphasizes the risk of upper respiratory dyskinesias associated with neuroleptic treatment and shows the feasibility of a new local treatment in this life-threatening disorder.

DOI: 10.1002/mds.870080220
PubMed: 8474494

Links to Exploration step

pubmed:8474494

Le document en format XML

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<name sortKey="Fenelon, G" sort="Fenelon, G" uniqKey="Fenelon G" first="G" last="Fénelon">G. Fénelon</name>
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<name sortKey="Logak, M" sort="Logak, M" uniqKey="Logak M" first="M" last="Logak">M. Logak</name>
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<term>Dyskinesia, Drug-Induced (drug therapy)</term>
<term>Electromyography (drug effects)</term>
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<term>Laryngeal Diseases (chemically induced)</term>
<term>Laryngeal Diseases (drug therapy)</term>
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<term>Neurologic Examination (drug effects)</term>
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<term>Laryngeal Muscles</term>
<term>Neurologic Examination</term>
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<term>Airway Obstruction</term>
<term>Dyskinesia, Drug-Induced</term>
<term>Laryngeal Diseases</term>
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<div type="abstract" xml:lang="en">We report a case of laryngeal dyskinesia resulting in severe rest and exercise dyspnea. A 51-year-old man treated for 2 years with flupentixol, an incisive neuroleptic, developed severe dyspnea due to intermittent, rhythmic, and dystonic movements of the vocal cords and upper airway. Local injections of botulinum toxin resulted in spectacular regression of laryngeal spasms and major improvement in breathing. This case emphasizes the risk of upper respiratory dyskinesias associated with neuroleptic treatment and shows the feasibility of a new local treatment in this life-threatening disorder.</div>
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