Hemiballismus from a parietal stroke in a Parkinson patient.
Identifieur interne : 003371 ( PubMed/Corpus ); précédent : 003370; suivant : 003372Hemiballismus from a parietal stroke in a Parkinson patient.
Auteurs : Motasem Al-Yacoub ; Joseph H. Friedman ; Hubert H. FernandezSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2004.
English descriptors
- KwdEn :
- Aged, Antipsychotic Agents (therapeutic use), Clozapine (therapeutic use), Dyskinesias (drug therapy), Dyskinesias (etiology), Dyskinesias (pathology), Humans, Infarction, Anterior Cerebral Artery (pathology), Magnetic Resonance Imaging (methods), Male, Parkinson Disease (complications), Parkinson Disease (pathology), Stroke (complications), Stroke (pathology).
- MESH :
- chemical , therapeutic use : Antipsychotic Agents, Clozapine.
- complications : Parkinson Disease, Stroke.
- drug therapy : Dyskinesias.
- etiology : Dyskinesias.
- methods : Magnetic Resonance Imaging.
- pathology : Dyskinesias, Infarction, Anterior Cerebral Artery, Parkinson Disease, Stroke.
- Aged, Humans, Male.
Abstract
Stroke-induced hemiballismus (HB) has been reported to improve motor function in people with Parkinson's disease (PD). We report on a patient who developed HB from a parietal infarct. The HB was improved by very low-dose clozapine but the HB did not improve the parkinsonism. This suggests that HB itself, whether from a lesion in the subthalamic nucleus or elsewhere, is not what improves motor function in PD; instead, the physiological function of the damaged structure is the determining factor.
DOI: 10.1002/mds.20204
PubMed: 15300673
Links to Exploration step
pubmed:15300673Le document en format XML
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<author><name sortKey="Al Yacoub, Motasem" sort="Al Yacoub, Motasem" uniqKey="Al Yacoub M" first="Motasem" last="Al-Yacoub">Motasem Al-Yacoub</name>
<affiliation><nlm:affiliation>Department of Clinical Neurosciences, Brown University School of Medicine, Providence, RI, USA.</nlm:affiliation>
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<author><name sortKey="Friedman, Joseph H" sort="Friedman, Joseph H" uniqKey="Friedman J" first="Joseph H" last="Friedman">Joseph H. Friedman</name>
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<author><name sortKey="Fernandez, Hubert H" sort="Fernandez, Hubert H" uniqKey="Fernandez H" first="Hubert H" last="Fernandez">Hubert H. Fernandez</name>
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<author><name sortKey="Friedman, Joseph H" sort="Friedman, Joseph H" uniqKey="Friedman J" first="Joseph H" last="Friedman">Joseph H. Friedman</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Antipsychotic Agents (therapeutic use)</term>
<term>Clozapine (therapeutic use)</term>
<term>Dyskinesias (drug therapy)</term>
<term>Dyskinesias (etiology)</term>
<term>Dyskinesias (pathology)</term>
<term>Humans</term>
<term>Infarction, Anterior Cerebral Artery (pathology)</term>
<term>Magnetic Resonance Imaging (methods)</term>
<term>Male</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (pathology)</term>
<term>Stroke (complications)</term>
<term>Stroke (pathology)</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antipsychotic Agents</term>
<term>Clozapine</term>
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<term>Stroke</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Dyskinesias</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dyskinesias</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Magnetic Resonance Imaging</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Dyskinesias</term>
<term>Infarction, Anterior Cerebral Artery</term>
<term>Parkinson Disease</term>
<term>Stroke</term>
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<front><div type="abstract" xml:lang="en">Stroke-induced hemiballismus (HB) has been reported to improve motor function in people with Parkinson's disease (PD). We report on a patient who developed HB from a parietal infarct. The HB was improved by very low-dose clozapine but the HB did not improve the parkinsonism. This suggests that HB itself, whether from a lesion in the subthalamic nucleus or elsewhere, is not what improves motor function in PD; instead, the physiological function of the damaged structure is the determining factor.</div>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<ArticleTitle>Hemiballismus from a parietal stroke in a Parkinson patient.</ArticleTitle>
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<Abstract><AbstractText>Stroke-induced hemiballismus (HB) has been reported to improve motor function in people with Parkinson's disease (PD). We report on a patient who developed HB from a parietal infarct. The HB was improved by very low-dose clozapine but the HB did not improve the parkinsonism. This suggests that HB itself, whether from a lesion in the subthalamic nucleus or elsewhere, is not what improves motor function in PD; instead, the physiological function of the damaged structure is the determining factor.</AbstractText>
<CopyrightInformation>Copyright 2004 Movement Disorder Society</CopyrightInformation>
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